Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_P20
(793 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VFC8|GYS_DROME Putative glycogen [starch] synthase 205 1e-52
sp|Q8MJ26|GYS1_MACMU Glycogen [starch] synthase, muscle 201 2e-51
sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle 200 4e-51
sp|P13834|GYS1_RABIT Glycogen [starch] synthase, muscle 197 4e-50
sp|Q9Z1E4|GYS1_MOUSE Glycogen [starch] synthase, muscle 196 5e-50
sp|P54859|GYS3_MOUSE Glycogen [starch] synthase, brain 191 1e-48
sp|P54840|GYS2_HUMAN Glycogen [starch] synthase, liver 187 3e-47
sp|P17625|GYS2_RAT Glycogen [starch] synthase, liver 182 7e-46
sp|O93869|GYS_NEUCR Glycogen [starch] synthase 176 5e-44
sp|P23337|GYS1_YEAST Glycogen [starch] synthase, isoform 1 168 2e-41
>sp|Q9VFC8|GYS_DROME Putative glycogen [starch] synthase
Length = 709
Score = 205 bits (522), Expect = 1e-52
Identities = 106/186 (56%), Positives = 133/186 (71%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFME+H+ DPKSYGIYIVDRR+ E SV
Sbjct: 536 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEEHISDPKSYGIYIVDRRYIGLENSV 595
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
+QL+++M++FS+ +RRQRI+ RNRTERLS+LLDW LG YY+++R+ AL P DY
Sbjct: 596 QQLSSFMMEFSRLNRRQRIIQRNRTERLSDLLDWRTLGIYYRQARVKALQAVYP---DYV 652
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTSLELDNDEIDEDAE 541
+SL S+ + SRP+S P SPT+S +TP + D D +DE+ E
Sbjct: 653 DELSL----YGSKNNLIFSRPHSEPPSPTSSRHTTPAPSVHGSD------DEDSVDEETE 702
Query: 542 RIELGL 559
ELG+
Sbjct: 703 LKELGI 708
>sp|Q8MJ26|GYS1_MACMU Glycogen [starch] synthase, muscle
Length = 737
Score = 201 bits (511), Expect = 2e-51
Identities = 100/182 (54%), Positives = 126/182 (69%), Gaps = 2/182 (1%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPS++TNLSGFGCFME+H+ DP +YGIYI+DRR RS ++S
Sbjct: 505 FPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSC 564
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT+++ F Q SRRQRI+ RNRTERLS+LLDW LG YY +R +AL+K P F Y
Sbjct: 565 SQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTY- 623
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTS--LELDNDEIDED 535
+ S+ + + + RP S P SP+ S S+P Q P + LE D++ DED
Sbjct: 624 -----EPSEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDEEDPRNGPLEEDSERYDED 678
Query: 536 AE 541
E
Sbjct: 679 EE 680
>sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle
Length = 737
Score = 200 bits (508), Expect = 4e-51
Identities = 101/182 (55%), Positives = 126/182 (69%), Gaps = 2/182 (1%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPS++TNLSGFGCFME+H+ DP +YGIYI+DRR RS ++S
Sbjct: 505 FPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSC 564
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT+++ F Q SRRQRI+ RNRTERLS+LLDW LG YY +R +AL+K P F Y
Sbjct: 565 SQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTYE 624
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTS--LELDNDEIDED 535
+E+D + + + RP S P SP+ S S+P Q P + LE D + DED
Sbjct: 625 P----NEAD--AAQGYRYPRPASVPPSPSLSRHSSPHQSEDEEDPRNGPLEEDGERYDED 678
Query: 536 AE 541
E
Sbjct: 679 EE 680
>sp|P13834|GYS1_RABIT Glycogen [starch] synthase, muscle
Length = 735
Score = 197 bits (500), Expect = 4e-50
Identities = 101/182 (55%), Positives = 123/182 (67%), Gaps = 2/182 (1%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPS++TNLSGFGCFME+H+ DP +YGIYI+DRR RS ++S
Sbjct: 505 FPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSC 564
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT+++ F Q SRRQRI+ RNRTERLS+LLDW LG YY +R +ALAK P F Y
Sbjct: 565 SQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALAKAFPDHFTYE 624
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTS--LELDNDEIDED 535
E+D + + + RP S P SP+ S S+P Q P E D + DED
Sbjct: 625 P----HEAD--ATQGYRYPRPASVPPSPSLSRHSSPHQSEDEEEPRDGLPEEDGERYDED 678
Query: 536 AE 541
E
Sbjct: 679 EE 680
>sp|Q9Z1E4|GYS1_MOUSE Glycogen [starch] synthase, muscle
Length = 738
Score = 196 bits (499), Expect = 5e-50
Identities = 100/182 (54%), Positives = 124/182 (68%), Gaps = 2/182 (1%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPS++TNLSGFGCFME+H+ DP +YGIYI+DRR RS ++S
Sbjct: 505 FPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSC 564
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT+++ F Q SRRQRI+ RNRTERLS+LLDW LG YY +R +ALAK P F Y
Sbjct: 565 SQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGRYYMSARHMALAKAFPDHFTYE 624
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTS--LELDNDEIDED 535
P +D + + + RP S P SP+ S S+P Q P L D++ DE+
Sbjct: 625 -PHEVD-----ATQGYRYPRPVSVPPSPSLSRHSSPHQSEDEEEPRDGPLGEDSERYDEE 678
Query: 536 AE 541
E
Sbjct: 679 EE 680
>sp|P54859|GYS3_MOUSE Glycogen [starch] synthase, brain
Length = 737
Score = 191 bits (486), Expect = 1e-48
Identities = 98/182 (53%), Positives = 122/182 (67%), Gaps = 2/182 (1%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPS++TNLSGFGCFME+H+ DP +YGIYI+DRR RS ++S
Sbjct: 504 FPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSC 563
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT+++ F Q SRR I+ RNRTERLS+LLDW LG YY +R +ALAK P F Y
Sbjct: 564 SQLTSFLYSFCQQSRRHGIIQRNRTERLSDLLDWKYLGRYYMSARHMALAKAFPDHFTYE 623
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTS--LELDNDEIDED 535
P +D + + + RP S P SP+ S S+P Q P L D++ DE+
Sbjct: 624 -PHEVD-----ATQGYRYPRPASVPPSPSLSRHSSPHQSEDEEEPRDGPLGEDSERYDEE 677
Query: 536 AE 541
E
Sbjct: 678 EE 679
>sp|P54840|GYS2_HUMAN Glycogen [starch] synthase, liver
Length = 703
Score = 187 bits (475), Expect = 3e-47
Identities = 95/180 (52%), Positives = 124/180 (68%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFM++HV DP +YGIYIVDRR RS ++S
Sbjct: 505 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQEHVADPTAYGIYIVDRRFRSPDDSC 564
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT ++ F + SRRQRI+ RNRTERLS+LLDW LG YY+ +R + L++ P F H
Sbjct: 565 NQLTKFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRYYQHARHLTLSRAFPDKF--H 622
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTSLELDNDEIDEDAE 541
++ + + + RP S P SP+ S S+P ++S E++++ DE+ E
Sbjct: 623 VELTSPP----TTEGFKYPRPSSVPPSPSGSQASSP-----QSSDVEDEVEDERYDEEEE 673
>sp|P17625|GYS2_RAT Glycogen [starch] synthase, liver
Length = 703
Score = 182 bits (463), Expect = 7e-46
Identities = 102/189 (53%), Positives = 125/189 (66%), Gaps = 3/189 (1%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFM++HV DP +YGIYIVD RS ++S
Sbjct: 505 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQEHVADPTAYGIYIVD-SVRSPDDSC 563
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT ++ F + SRRQRI+ RNRTERLS+LLDW LG YY+ +R + L++ P F Y
Sbjct: 564 NQLTQFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRYYQHARHLTLSRAFPDKF-YL 622
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSPTASGISTPKQESGRTSPTSLELDNDE---IDE 532
P S +D F RP S P SP+ S S+P ++S E D DE +E
Sbjct: 623 EPTSPPTTDGFK-----YPRPSSVPPSPSGSQTSSP-----QSSDVENEGDEDERYDEEE 672
Query: 533 DAERIELGL 559
+AER L +
Sbjct: 673 EAERDRLNI 681
>sp|O93869|GYS_NEUCR Glycogen [starch] synthase
Length = 706
Score = 176 bits (447), Expect = 5e-44
Identities = 88/157 (56%), Positives = 110/157 (70%), Gaps = 1/157 (0%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVIDPKSYGIYIVDRRHRSGEESV 181
F SYYEPWGYTPAECTVMG+PS+TTNLSGFGC+ME+ + + YGIYIVDRR + ++SV
Sbjct: 495 FASYYEPWGYTPAECTVMGVPSITTNLSGFGCYMEELIENSSDYGIYIVDRRSKGVDDSV 554
Query: 182 EQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFDYH 361
QLT YM +F+Q SRRQRI RNRTERLS+LLDW +G Y K+R +AL + P F+
Sbjct: 555 NQLTQYMFEFTQKSRRQRINQRNRTERLSDLLDWKRMGMEYVKARQLALRRAYPTSFN-- 612
Query: 362 TPISLDESDRFSEKSWHMSRPYSAPGSP-TASGISTP 469
+E D +SRP+S PGSP +G+ TP
Sbjct: 613 ---GEEEEDFIPGVEQKISRPFSVPGSPRDRTGMMTP 646
>sp|P23337|GYS1_YEAST Glycogen [starch] synthase, isoform 1
Length = 708
Score = 168 bits (425), Expect = 2e-41
Identities = 92/197 (46%), Positives = 118/197 (59%), Gaps = 19/197 (9%)
Frame = +2
Query: 2 FPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEDHVI--DPKSYGIYIVDRRHRSGEE 175
FPSYYEPWGYTPAECTVMG+PS+TTN+SGFG +MED + K YGIYIVDRR +S +E
Sbjct: 504 FPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETDQAKDYGIYIVDRRFKSPDE 563
Query: 176 SVEQLTNYMLDFSQYSRRQRIVLRNRTERLSELLDWNNLGFYYKKSRIIALAKQSPHLFD 355
SVEQL +YM +F +RRQRI RNRTERLS+LLDW +G Y K+R + L + P F
Sbjct: 564 SVEQLADYMEEFVNKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLGLRRAYPEQFK 623
Query: 356 YHTPISLDESDR---FSEKSWHMSRPYSAPGSPTASGISTPKQESGRTS----------- 493
++ +++ K + ++RP S PGSP ST G
Sbjct: 624 QLVGETISDANMNTLAGGKKFKIARPLSVPGSPKVRSNSTVYMTPGDLGTLQDANNADDY 683
Query: 494 ---PTSLELDNDEIDED 535
T+ +DND+ D D
Sbjct: 684 FNLSTNGAIDNDDDDND 700
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,601,568
Number of Sequences: 369166
Number of extensions: 1897943
Number of successful extensions: 5254
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5041
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5233
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)