Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_P09
(737 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9QUM9|PSA6_MOUSE Proteasome subunit alpha type 6 (Prote... 272 6e-73
sp|P60900|PSA6_HUMAN Proteasome subunit alpha type 6 (Prote... 271 1e-72
sp|Q9XZJ4|PSA6_DROME Proteasome subunit alpha type 6 (20S p... 258 2e-68
sp|O81146|PSA6A_ARATH Proteasome subunit alpha type 6-A (Pr... 233 5e-61
sp|O81147|PSA6B_ARATH Proteasome subunit alpha type 6-B (Pr... 232 9e-61
sp|O48551|PSA6_SOYBN Proteasome subunit alpha type 6 (20S p... 224 1e-58
sp|O17586|PSA6_CAEEL Proteasome subunit alpha type 6 (Prote... 224 2e-58
sp|Q9XG77|PSA6_TOBAC Proteasome subunit alpha type 6 (20S p... 224 2e-58
sp|Q9LSU3|PSA6_ORYSA Proteasome subunit alpha type 6 (20S p... 219 6e-57
sp|O94517|PSA6_SCHPO Probable proteasome subunit alpha type 6 215 1e-55
>sp|Q9QUM9|PSA6_MOUSE Proteasome subunit alpha type 6 (Proteasome iota chain) (Macropain
iota chain) (Multicatalytic endopeptidase complex iota
chain)
Length = 246
Score = 272 bits (696), Expect = 6e-73
Identities = 134/239 (56%), Positives = 178/239 (74%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGSS-GFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GSS GFDR++TIFSPEGRL+QVEYAFKAI+ GL SV +RG +C V+ TQ+K+PDK+
Sbjct: 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
++ ++ T LFKITES GCVMTGM D RSQV RA+ EAA GYE+ D +C+ IAD
Sbjct: 61 LDSSTVTHLFKITESIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
I+QVYTQ+AEMRPLGC MI + D E P +YK DP+G+ G +A A G KQ E+ S+L
Sbjct: 121 ISQVYTQNAEMRPLGCCMILIGID-EEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK++K ++T ++ VE AI CLS V S+DFK E+E+G+VT + P FR+L++ +ID +
Sbjct: 180 EKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAH 238
>sp|P60900|PSA6_HUMAN Proteasome subunit alpha type 6 (Proteasome iota chain) (Macropain
iota chain) (Multicatalytic endopeptidase complex iota
chain) (27 kDa prosomal protein) (PROS-27) (p27K)
sp|P60901|PSA6_RAT Proteasome subunit alpha type 6 (Proteasome iota chain) (Macropain
iota chain) (Multicatalytic endopeptidase complex iota
chain)
Length = 246
Score = 271 bits (693), Expect = 1e-72
Identities = 133/239 (55%), Positives = 178/239 (74%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGSS-GFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GSS GFDR++TIFSPEGRL+QVEYAFKAI+ GL SV +RG +C V+ TQ+K+PDK+
Sbjct: 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKL 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
++ ++ T LFKITE+ GCVMTGM D RSQV RA+ EAA GYE+ D +C+ IAD
Sbjct: 61 LDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
I+QVYTQ+AEMRPLGC MI + D E P +YK DP+G+ G +A A G KQ E+ S+L
Sbjct: 121 ISQVYTQNAEMRPLGCCMILIGID-EEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK++K ++T ++ VE AI CLS V S+DFK E+E+G+VT + P FR+L++ +ID +
Sbjct: 180 EKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAH 238
>sp|Q9XZJ4|PSA6_DROME Proteasome subunit alpha type 6 (20S proteasome subunit alpha-1)
Length = 244
Score = 258 bits (658), Expect = 2e-68
Identities = 129/239 (53%), Positives = 178/239 (74%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGSS-GFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GSS GFDR++TIFSPEGRL+QVEYAFKAI+ + + +V ++ +C VVATQ+K+ +K
Sbjct: 1 MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEKN 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
I + T LF+IT+ GC MTG I D RSQV +A+ EAA GYEM D +CR IAD
Sbjct: 61 IVPETVTHLFRITKDIGCAMTGRIADSRSQVQKARYEAANFRYKYGYEMPVDVLCRRIAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
INQVYTQ+AEMRPLGCSM+ ++YD E P +YKTDP+G+ +G +A +VGAK LEA SYL
Sbjct: 121 INQVYTQNAEMRPLGCSMVLIAYDNEIG-PSVYKTDPAGYFSGFKACSVGAKTLEANSYL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK + N + ++A+++AI+CLS V ++DFK +EIG+V++ P FR+L + +I+E+
Sbjct: 180 EKKYKPN--LSEEKAIQLAISCLSSVLAIDFKPNGIEIGVVSKSDPTFRILDEREIEEH 236
>sp|O81146|PSA6A_ARATH Proteasome subunit alpha type 6-A (Proteasome subunit alpha type 1)
(20S proteasome alpha subunit A-1) (Proteasome component
1)
Length = 246
Score = 233 bits (593), Expect = 5e-61
Identities = 119/239 (49%), Positives = 165/239 (69%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGS-SGFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GS +G+DR++TIFSPEGRLFQVEYAFKA+ G+ S+G+RG + V TQ+K+PDK+
Sbjct: 1 MSRGSGAGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKL 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
++++S T LF IT+ G V TG+ D RS V +A+ +AA GYEM D + + IAD
Sbjct: 61 LDQSSVTHLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
+QVYTQ A MRPLG + + D E N PLLYK DP+G GH+A + G K+ EA ++L
Sbjct: 121 KSQVYTQHAYMRPLGVVAMVMGVD-EENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK+++N FT DE V+ AI+ L V DFKA E+E+G+V + P FR L+ E+I+E+
Sbjct: 180 EKKMKENPSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEH 238
>sp|O81147|PSA6B_ARATH Proteasome subunit alpha type 6-B (Proteasome subunit alpha type 1)
(20S proteasome alpha subunit A-2)
Length = 246
Score = 232 bits (591), Expect = 9e-61
Identities = 120/239 (50%), Positives = 163/239 (68%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGS-SGFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GS +G+DR++TIFSPEGRLFQVEYAFKA+ G+ S+G+RG + V TQ+K+PDK+
Sbjct: 1 MSRGSGAGYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKL 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
++++S + LF +T+ G + TGM D RS V +A+ EAA GYEM D + + IAD
Sbjct: 61 LDQSSVSHLFPVTKYLGLLATGMTADSRSLVQQARNEAAEFRFQYGYEMPADILAKWIAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
+QVYTQ A MRPLG + L D E PLLYK DP+G GH+A + G K+ EA ++L
Sbjct: 121 KSQVYTQHAYMRPLGVVAMVLGID-EERGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK+++N FT DE V+ AI+ L V DFKA E+E+G+V D P FR L E+IDE+
Sbjct: 180 EKKMKENPAFTYDETVQTAISALQSVLQEDFKATEIEVGVVRADDPLFRSLRTEEIDEH 238
>sp|O48551|PSA6_SOYBN Proteasome subunit alpha type 6 (20S proteasome alpha subunit A)
(20S proteasome subunit alpha-1) (Proteasome iota
subunit)
Length = 246
Score = 224 bits (572), Expect = 1e-58
Identities = 116/239 (48%), Positives = 160/239 (66%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGSSG-FDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GS G ++R++TIFSPEGRLFQVEYAFKA+ G+ S+G+RG + V T +K+PDK+
Sbjct: 1 MSRGSGGGYNRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSICVVTHKKVPDKL 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
++ S T LF IT+ G + TGM D R+ V +A+ EAA GYEM D + + IAD
Sbjct: 61 LDNTSVTHLFPITKYLGLLATGMTADARTLVQQARNEAAEFRFTYGYEMPVDVLAKWIAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
+QVYTQ A MRPLG + L D E+ P LYK DP+G GH+A + G K EA ++L
Sbjct: 121 KSQVYTQHAYMRPLGVVAMVLGIDDEYG-PQLYKCDPAGHYFGHKATSAGLKDQEAINFL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK++ + FT +E V+ AI+ L V DFKA E+E+G+V +D P FRVL+ ++IDE+
Sbjct: 180 EKKMKNDPSFTYEETVQTAISALQSVLQEDFKATEIEVGVVRKDNPEFRVLTTDEIDEH 238
>sp|O17586|PSA6_CAEEL Proteasome subunit alpha type 6 (Proteasome subunit alpha 1)
Length = 246
Score = 224 bits (571), Expect = 2e-58
Identities = 108/239 (45%), Positives = 167/239 (69%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGSS-GFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GSS GFDR++TIFSPEGR++QVEYAFKAI+ L +V ++G + V+A Q+++PD +
Sbjct: 1 MSRGSSAGFDRHITIFSPEGRVYQVEYAFKAINSTNLTAVAVKGADAAVIAVQKRVPDSL 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
I ++ T +++I++S GC GMIPD + Q+ RAQ EAA GY+M C+ + + +AD
Sbjct: 61 IVADTVTSVYQISQSVGCCAIGMIPDAKFQIKRAQGEAASWKYKNGYDMPCELLAKKMAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
+NQ YTQ+AEMR LGC+++ +SYD E P +Y+ DP+G+ G + V+VG KQL A S+L
Sbjct: 121 LNQYYTQNAEMRSLGCALLFISYDDE-KGPEVYRVDPAGYYRGMKGVSVGVKQLPATSFL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK++K E T EA+E+AI L +D ++ +LE+ +VT+D F L+ ++++ +
Sbjct: 180 EKKIKKKSELTSTEAIELAIEALQTSLGIDVRSKDLEVVVVTKDNSKFTKLTSDQVEHH 238
>sp|Q9XG77|PSA6_TOBAC Proteasome subunit alpha type 6 (20S proteasome alpha subunit A)
(20S proteasome subunit alpha-1)
Length = 246
Score = 224 bits (570), Expect = 2e-58
Identities = 115/239 (48%), Positives = 163/239 (68%), Gaps = 1/239 (0%)
Frame = +2
Query: 23 MTSGSSG-FDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKM 199
M+ GS G +DR++TIFSPEGRLFQVEYAFKA+ G+ S+G+RG + V TQ+K+PDK+
Sbjct: 1 MSRGSGGGYDRHITIFSPEGRLFQVEYAFKAVKAAGITSIGVRGKDSVCVVTQKKVPDKL 60
Query: 200 IERNSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIAD 379
+++ S + LF IT+ G + TGM D R+ V +A+ EAA GYEM D + + IAD
Sbjct: 61 LDQTSVSHLFPITKYLGLLATGMTADARTLVQQARNEAAEFRFKYGYEMPVDVLSKWIAD 120
Query: 380 INQVYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYL 559
+QVYTQ A MRPLG + L D E P L+K DP+G GH+A + G+K+ EA ++L
Sbjct: 121 KSQVYTQHAYMRPLGVVAMILGID-EEKGPQLFKCDPAGHFFGHKATSAGSKEQEAINFL 179
Query: 560 EKKLRKNKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
EKK++ + F+ +E V+ AI+ L V DFKA E+E+G+V ++ P FRVL+ E+IDE+
Sbjct: 180 EKKMKNDPAFSYEETVQTAISALQSVLQEDFKASEIEVGVVKKEDPIFRVLTTEEIDEH 238
>sp|Q9LSU3|PSA6_ORYSA Proteasome subunit alpha type 6 (20S proteasome alpha subunit A)
(20S proteasome subunit alpha-1)
Length = 246
Score = 219 bits (558), Expect = 6e-57
Identities = 111/233 (47%), Positives = 158/233 (67%)
Frame = +2
Query: 38 SGFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKMIERNSA 217
+G+DR++TIFSPEGRL+QVEYAFKA+ G+ S+G+RG + V TQ+K+PDK+++ S
Sbjct: 7 AGYDRHITIFSPEGRLYQVEYAFKAVKSAGVTSIGVRGKDSVCVVTQKKVPDKLLDHTSV 66
Query: 218 TRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIADINQVYT 397
T LF IT+ G + TG+ D RS V +A+ EAA GYEM D + + IAD QVYT
Sbjct: 67 THLFPITKYIGLLATGLTADARSLVYQARNEAAEFRFKWGYEMPVDVLAKWIADKAQVYT 126
Query: 398 QSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYLEKKLRK 577
Q A MRPLG + L YD E N L+K DP+G GH+A + G K+ EA ++LEKK++
Sbjct: 127 QHAYMRPLGVVAMVLGYDEEKNAQ-LFKCDPAGHFFGHKATSAGLKEQEAINFLEKKMKD 185
Query: 578 NKEFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
+ +F+ +E V++AI+ L V DFKA E+E+G+V +D FR L+ E+ID++
Sbjct: 186 DPQFSYEETVQIAISALQSVLQEDFKATEIEVGVVRKDDRVFRALTTEEIDQH 238
>sp|O94517|PSA6_SCHPO Probable proteasome subunit alpha type 6
Length = 244
Score = 215 bits (547), Expect = 1e-55
Identities = 115/237 (48%), Positives = 157/237 (66%), Gaps = 1/237 (0%)
Frame = +2
Query: 29 SGSSGFDRYMTIFSPEGRLFQVEYAFKAISLDGLLSVGIRGNNCGVVATQRKIPDKMIER 208
S + GFDR +T+FSPEGRL+QVEYAFKA + G+ SVG+ G NC V +Q+K+PDK+I+
Sbjct: 2 SQARGFDRTITVFSPEGRLYQVEYAFKAFNNAGITSVGVTGKNCACVISQKKVPDKLIDA 61
Query: 209 NSATRLFKITESTGCVMTGMIPDCRSQVSRAQMEAAXXXXXXGYEMSCDNICRCIADINQ 388
++ +F IT+ GCVMTG I D R+QVSRA+ EAA GY M CD + + +A+I Q
Sbjct: 62 STVKHVFPITKGIGCVMTGSIADARAQVSRARSEAAEFEYKNGYPMPCDVLAKRMANIAQ 121
Query: 389 VYTQSAEMRPLGCSMIALSYDIEFNKPLLYKTDPSGFVAGHRAVAVGAKQLEAKSYLEKK 568
V TQ A MRPLG +M ++ D E P L+K DP+GF G++A + G KQ E ++LEK+
Sbjct: 122 VSTQRAAMRPLGVAMTLVAVDDEIG-PSLFKLDPAGFYIGYKATSAGPKQTETINWLEKR 180
Query: 569 LRKNK-EFTLDEAVEVAINCLSHVQSVDFKAGELEIGIVTQDCPYFRVLSDEKIDEY 736
+K+ L + VE I L S DFK+ EL+IG+V D P FRVLS E+I+ +
Sbjct: 181 FKKDGIPSNLTDTVETGIQALMSSLSTDFKSTELQIGVVEDDKP-FRVLSVEEIEAH 236
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,638,536
Number of Sequences: 369166
Number of extensions: 1623643
Number of successful extensions: 4228
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3895
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3984
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6631293200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)