Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_O09
(851 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13688|CEAM1_HUMAN Carcinoembryonic antigen-related cell... 40 0.008
sp|P52583|VGFR2_COTJA Vascular endothelial growth factor re... 36 0.15
sp|Q16557|PSG3_HUMAN Pregnancy-specific beta-1-glycoprotein... 35 0.20
sp|Q00887|PSG9_HUMAN Pregnancy-specific beta-1-glycoprotein... 35 0.20
sp|P11464|PSG1_HUMAN Pregnancy-specific beta-1-glycoprotein... 35 0.20
sp|Q60625|ICAM5_MOUSE Intercellular adhesion molecule 5 pre... 35 0.26
sp|Q9VN14|CONT_DROME Contactin precursor 35 0.34
sp|Q9UQ72|PSGB_HUMAN Pregnancy-specific beta-1-glycoprotein... 34 0.45
sp|Q9UQ74|PSG8_HUMAN Pregnancy-specific beta-1-glycoprotein... 34 0.45
sp|P20241|NRG_DROME Neuroglian precursor 33 0.77
>sp|P13688|CEAM1_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 1 precursor
(Biliary glycoprotein 1) (BGP-1) (Antigen CD66) (CD66a
antigen)
Length = 526
Score = 40.0 bits (92), Expect = 0.008
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 27/209 (12%)
Frame = +3
Query: 105 IGDITSKDAGTYTLEI--TDGANQLVMTIYTVV--LGAPSLDDPNCLPLVAYVHERESKS 272
I ++T D G YTL++ +D N+ + V L PS+ N P V ++++ +
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNP----VEDKDAVA 164
Query: 273 FSCTFRNLPDSLVLKINSMQIPLTQSLDISR---------INLGKTYPFLGELHFEVSPN 425
F+C + + IN+ +P++ L +S + T P+ E+ VS N
Sbjct: 165 FTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSAN 224
Query: 426 SYSPSEMIKMTYTVSKLTITQGQTSYQDHNVM----FLAKNK--------YGSIGRSSSV 569
P + +TY TI+ T Y+ + + A N G+ +S+
Sbjct: 225 RSDP-VTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQE 283
Query: 570 YVVPNLKENIQSS--PEAYNCTDVCNSDT 650
+PN+ N S A N CN T
Sbjct: 284 LFIPNITVNNSGSYTCHANNSVTGCNRTT 312
>sp|P52583|VGFR2_COTJA Vascular endothelial growth factor receptor 2 precursor (VEGFR-2)
(Endothelial kinase receptor EK1) (Quek 1) (Quek1)
Length = 1348
Score = 35.8 bits (81), Expect = 0.15
Identities = 48/197 (24%), Positives = 84/197 (42%), Gaps = 8/197 (4%)
Frame = +3
Query: 36 WKFNGNPIFQSSNLRVNEYSVQFIGDITSKDAGTYTLEITDGANQLVMT-IYTVVLGAPS 212
W NG I + +++ V I + T KDAG YT+ +T+ N++ +T+++ P
Sbjct: 355 WYKNGKVINANHTVKLGYALV--ITEATEKDAGNYTVVLTNPTNKMQKRHTFTLLVNVPP 412
Query: 213 LDDPNCL--PLVAYVHERESKSFSCTFRNLPDSLVLKINSMQIPLTQSLDISRINLGKTY 386
N L P+ +Y + +++ +CT +P + + Q+ + ++ LG
Sbjct: 413 QIGENALMAPVDSYKY-GSTQALTCTIYAVPPPAAV-LWYWQLEEECTFSPQKVRLGAN- 469
Query: 387 PFLGELHFEVSPNSYSPSEMIKM-TYTVSKLTITQGQTSYQDHNVMFL----AKNKYGSI 551
P+ +S IK T++ T T Q NV L A N+ GS
Sbjct: 470 PYACRKWKVISERKGGNQVEIKQRVVTIAGKTKTVSTLVIQAANVSALYRCMATNRAGSS 529
Query: 552 GRSSSVYVVPNLKENIQ 602
R S +V L+ N+Q
Sbjct: 530 ERVISFHVTRGLEINLQ 546
>sp|Q16557|PSG3_HUMAN Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3)
(Carcinoembryonic antigen SG5)
Length = 428
Score = 35.4 bits (80), Expect = 0.20
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 7/94 (7%)
Frame = +3
Query: 105 IGDITSKDAGTYTLEIT---DG----ANQLVMTIYTVVLGAPSLDDPNCLPLVAYVHERE 263
I ++T +DAG+YTL I DG T+Y + PS+ N P + E
Sbjct: 109 IQNVTREDAGSYTLHIVKRGDGTRGETGHFTFTLY-LETPKPSISSSNLYPR----EDME 163
Query: 264 SKSFSCTFRNLPDSLVLKINSMQIPLTQSLDISR 365
+ S +C S + +N +P+T SL +S+
Sbjct: 164 AVSLTCDPETPDASYLWWMNGQSLPMTHSLQLSK 197
Score = 31.6 bits (70), Expect = 2.9
Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Frame = +3
Query: 21 DAKYLWKFNGN--PIFQSSNLRVNEYSVQFIGDITSKDAGTYTLEITDGANQLVMTIYTV 194
DA YLW NG P+ S L N+ ++ F+ +T AG Y EI + + T+
Sbjct: 175 DASYLWWMNGQSLPMTHSLQLSKNKRTL-FLFGVTKYTAGPYECEIRNPVSASRSDPVTL 233
Query: 195 VLGAPSLDDPNCLPLVAYVHERESK---SFSCTFRNLPDSLVLKINSMQIPLT 344
L P L P + ++ RE+K +F+C ++ + + +N +P++
Sbjct: 234 NL-LPKLPKPYI--TINNLNpreNKDVLAFTCEPKSENYTYIWWLNGQSLPVS 283
>sp|Q00887|PSG9_HUMAN Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9)
(Pregnancy-specific glycoprotein 9) (Pregnancy-specific
beta-1 glycoprotein B) (PS-beta-B) (PS34)
(Pregnancy-specific glycoprotein 7) (PSG7)
Length = 426
Score = 35.4 bits (80), Expect = 0.20
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Frame = +3
Query: 105 IGDITSKDAGTYTLEITDGANQLVMTI----YTVVLGAPS--LDDPNCLPLVAYVHERES 266
I ++T KDAGTYTL I ++ I +T+ L P + N P A E+
Sbjct: 109 IQNVTRKDAGTYTLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNpreA----MEA 164
Query: 267 KSFSCTFRNLPDSLVLKINSMQIPLTQSLDISRIN-----LGKTYPFLGELHFEV-SPNS 428
C L S + +N +P+T L +S+ N G T G E+ +P S
Sbjct: 165 VRLICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVS 224
Query: 429 YSPSEMIKM 455
S S+ + +
Sbjct: 225 ASRSDPVTL 233
>sp|P11464|PSG1_HUMAN Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1)
(Pregnancy-specific beta-1 glycoprotein C/D)
(PS-beta-C/D) (Fetal liver non-specific cross-reactive
antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen)
Length = 419
Score = 35.4 bits (80), Expect = 0.20
Identities = 30/113 (26%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Frame = +3
Query: 105 IGDITSKDAGTYTLEITDG-------ANQLVMTIYTVVLGAPSLDDPNCLPLVAYVHERE 263
I ++T +DAG+YTL I G + T++ + PS+ N P E
Sbjct: 109 IQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLH-LETPKPSISSSNLNPR----ETME 163
Query: 264 SKSFSCTFRNLPDSLVLKINSMQIPLTQSLDISRINLGKTYPFLGELHFEVSP 422
+ S +C S + +N +P+T SL +S N +T LG + P
Sbjct: 164 AVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETN--RTLFLLGVTKYTAGP 214
Score = 33.1 bits (74), Expect = 1.0
Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 4/112 (3%)
Frame = +3
Query: 21 DAKYLWKFNGNPIFQSSNLRVNEYS-VQFIGDITSKDAGTYTLEITDGANQLVMTIYTVV 197
DA YLW NG + + +L+++E + F+ +T AG Y EI + + T+
Sbjct: 175 DASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLN 234
Query: 198 LGAPSLDDPNCLPLVAYVHERESK---SFSCTFRNLPDSLVLKINSMQIPLT 344
L P L P + ++ RE+K +F+C ++ + + +N +P++
Sbjct: 235 L-LPKLPKPYI--TINNLNpreNKDVLNFTCEPKSENYTYIWWLNGQSLPVS 283
>sp|Q60625|ICAM5_MOUSE Intercellular adhesion molecule 5 precursor (ICAM-5)
(Telencephalin)
Length = 917
Score = 35.0 bits (79), Expect = 0.26
Identities = 22/74 (29%), Positives = 33/74 (44%)
Frame = +3
Query: 105 IGDITSKDAGTYTLEITDGANQLVMTIYTVVLGAPSLDDPNCLPLVAYVHERESKSFSCT 284
+G +T AGTY +G Q V + V AP+LD C + ++ E+ S SC
Sbjct: 457 LGPVTRALAGTYRCTAVNGQGQAVKDVTLTVEYAPALDSVGCPEHITWLEGTEA-SLSCV 515
Query: 285 FRNLPDSLVLKINS 326
+P V + S
Sbjct: 516 APGVPPPSVSCVRS 529
>sp|Q9VN14|CONT_DROME Contactin precursor
Length = 1390
Score = 34.7 bits (78), Expect = 0.34
Identities = 47/205 (22%), Positives = 79/205 (38%), Gaps = 9/205 (4%)
Frame = +3
Query: 30 YLWKFNGNPIFQSSNLRVNEYSVQFIGDITSKDAGTYTLEITDGANQLVMTIYTVVLGAP 209
Y W G P+ Q + +N V I + T+ D G Y+ IT+ L+ +IY + P
Sbjct: 603 YNWTRQGLPL-QRNAYTINYGRVLIIQNATTNDNGEYSCTITNPRKTLMKSIYINIQMRP 661
Query: 210 SLDDPNCLPLVAYVHERESK-SFSCTFRNLPDSLVLKINSMQIPLTQSLDISRINLGK-- 380
+PL + + S +F C +PD+ N + LD + IN +
Sbjct: 662 QF----TIPLKDMIKDYNSDVTFICEAFAIPDA-----NYTWYKNAERLDPANINRDRYI 712
Query: 381 ------TYPFLGELHFEVSPNSYSPSEMIKMTYTVSKLTITQGQTSYQDHNVMFLAKNKY 542
T FL E + + +K +++ ++L + + S++ H +
Sbjct: 713 IQDNVLTIKFL-EKDKDDAMYQCGAQNQLKTSFSSAQLRVLSMKPSFKKHPL-------- 763
Query: 543 GSIGRSSSVYVVPNLKENIQSSPEA 617
S VY V N I PEA
Sbjct: 764 -----ESEVYAVYNGNTTIVCDPEA 783
>sp|Q9UQ72|PSGB_HUMAN Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11)
(PSBG-13)
Length = 332
Score = 34.3 bits (77), Expect = 0.45
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Frame = +3
Query: 21 DAKYLWKFNGNPIFQSSNLRVNEYS-VQFIGDITSKDAGTYTLEI-TDGANQLVMTIYTV 194
DA YLW NG + + ++++E + F+ +T AG Y EI G+ +
Sbjct: 175 DASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLN 234
Query: 195 VLGAPSLDDPNCLPLVAYVHERESKSFSC 281
+L P L P P V + E+ SC
Sbjct: 235 LLHGPDL--PRIFPSVTSYYSGENLDLSC 261
Score = 30.4 bits (67), Expect = 6.5
Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 7/96 (7%)
Frame = +3
Query: 105 IGDITSKDAGTYTLEIT---DG----ANQLVMTIYTVVLGAPSLDDPNCLPLVAYVHERE 263
I ++T +DAG+YTL I DG T+Y + PS+ N P A E
Sbjct: 109 IQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLY-LETPKPSISSSNLNpreA----ME 163
Query: 264 SKSFSCTFRNLPDSLVLKINSMQIPLTQSLDISRIN 371
+ +C S + +N +P+T + +S N
Sbjct: 164 TVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETN 199
>sp|Q9UQ74|PSG8_HUMAN Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8)
Length = 426
Score = 34.3 bits (77), Expect = 0.45
Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 4/112 (3%)
Frame = +3
Query: 21 DAKYLWKFNGNPIFQSSNLRVNEYS-VQFIGDITSKDAGTYTLEITDGANQLVMTIYTVV 197
DA YLW NG + S L+++E + F+ +T AG Y EI + + +T+
Sbjct: 175 DASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLN 234
Query: 198 LGAPSLDDPNCLPLVAYVHERESK---SFSCTFRNLPDSLVLKINSMQIPLT 344
L P L P + + RE+K +F+C ++ + + +N +P++
Sbjct: 235 L-LPKLPKPYI--TINNLKpreNKDVLNFTCEPKSENYTYIWWLNGQSLPVS 283
Score = 33.5 bits (75), Expect = 0.77
Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Frame = +3
Query: 105 IGDITSKDAGTYTLEITDGANQ-------LVMTIYTVVLGAPSLDDPNCLPLVAYVHERE 263
I ++T +DAG+YTL I G ++ T+Y + PS+ P A E
Sbjct: 109 IQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLY-LETPKPSISSSKLNpreA----ME 163
Query: 264 SKSFSCTFRNLPDSLVLKINSMQIPLTQSLDISRINLGKTYPFLGELHFEVSP 422
+ S +C S + +N +P++ L +S N +T LG + P
Sbjct: 164 AVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETN--RTLFLLGVTKYTAGP 214
>sp|P20241|NRG_DROME Neuroglian precursor
Length = 1302
Score = 33.5 bits (75), Expect = 0.77
Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 1/107 (0%)
Frame = +3
Query: 33 LWKFNGNPIFQSSNLRVNEYSVQFIGDITS-KDAGTYTLEITDGANQLVMTIYTVVLGAP 209
+W +G I S + Y + T+ DAGTYT ++++G ++++L
Sbjct: 279 VWSKDGQRIQWSDRITQGHYGKSLVIRQTNFDDAGTYTCDVSNGVGN--AQSFSIILNVN 336
Query: 210 SLDDPNCLPLVAYVHERESKSFSCTFRNLPDSLVLKINSMQIPLTQS 350
S+ P +A E E F C +P+ + I++ + P+ QS
Sbjct: 337 SVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGK-PIEQS 382
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,160,703
Number of Sequences: 369166
Number of extensions: 1805092
Number of successful extensions: 4204
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4012
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4204
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)