Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_O08
(834 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q86YQ8|CPNE8_HUMAN Copine-8 (Copine VIII) 165 2e-40
sp|Q9DC53|CPNE8_MOUSE Copine-8 (Copine VIII) 165 2e-40
sp|Q9HCH3|CPNE5_HUMAN Copine-5 (Copine V) 157 3e-38
sp|Q8JZW4|CPNE5_MOUSE Copine-5 (Copine V) 157 3e-38
sp|Q5RAE1|CPNE3_PONPY Copine-3 (Copine III) 157 4e-38
sp|Q8BT60|CPNE3_MOUSE Copine-3 (Copine III) 155 1e-37
sp|O75131|CPNE3_HUMAN Copine-3 (Copine III) 155 2e-37
sp|Q8C166|CPNE1_MOUSE Copine-1 (Copine I) 154 3e-37
sp|Q99829|CPNE1_HUMAN Copine-1 (Copine I) 152 1e-36
sp|Q96FN4|CPNE2_HUMAN Copine-2 (Copine II) 152 1e-36
>sp|Q86YQ8|CPNE8_HUMAN Copine-8 (Copine VIII)
Length = 564
Score = 165 bits (417), Expect = 2e-40
Identities = 88/191 (46%), Positives = 119/191 (62%)
Frame = +3
Query: 3 NDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCF 182
+D++FPA GFGA++PPD +I HE+ LNG+ +NPYC G EGV++AY ++LK V+L GPT F
Sbjct: 356 SDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNF 415
Query: 183 SPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXK 362
+PVI H++R A + + G YFVLLI+TDG + D +TK+++V S LP +
Sbjct: 416 APVINHVARYASSVKDGSQYFVLLIVTDGIISDMAQTKESIVNASKLPMSIIIVGVGPAE 475
Query: 363 FSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAEL 542
F M LD D + + A RD VQFV R Y+ D S N S LAKDVLAE+
Sbjct: 476 FDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEI 531
Query: 543 PYQVNEYMHRK 575
P Q YM +
Sbjct: 532 PEQFLSYMRAR 542
>sp|Q9DC53|CPNE8_MOUSE Copine-8 (Copine VIII)
Length = 564
Score = 165 bits (417), Expect = 2e-40
Identities = 88/191 (46%), Positives = 119/191 (62%)
Frame = +3
Query: 3 NDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCF 182
+D++FPA GFGA++PPD +I HE+ LNG+ +NPYC G EGV++AY ++LK V+L GPT F
Sbjct: 356 SDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNF 415
Query: 183 SPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXK 362
+PVI H++R A + + G YFVLLI+TDG + D +TK+++V S LP +
Sbjct: 416 APVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAE 475
Query: 363 FSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAEL 542
F M LD D + + A RD VQFV R Y+ D S N S LAKDVLAE+
Sbjct: 476 FDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEI 531
Query: 543 PYQVNEYMHRK 575
P Q YM +
Sbjct: 532 PEQFLSYMRAR 542
>sp|Q9HCH3|CPNE5_HUMAN Copine-5 (Copine V)
Length = 593
Score = 157 bits (398), Expect = 3e-38
Identities = 82/188 (43%), Positives = 118/188 (62%)
Frame = +3
Query: 3 NDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCF 182
+D++FPA GFGA++PPD ++ HE+PLNG+ ENP C G +G+++AY ++L+ V+L GPT F
Sbjct: 375 SDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNF 434
Query: 183 SPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXK 362
+PV+ H++R A A + G Y VLLI+TDG + D +TK+A+V + LP +
Sbjct: 435 APVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAE 494
Query: 363 FSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAEL 542
F M LD D + + A RD VQFV R Y+ D + N S LA+DVLAE+
Sbjct: 495 FDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEI 550
Query: 543 PYQVNEYM 566
P Q+ YM
Sbjct: 551 PDQLVSYM 558
>sp|Q8JZW4|CPNE5_MOUSE Copine-5 (Copine V)
Length = 593
Score = 157 bits (397), Expect = 3e-38
Identities = 82/188 (43%), Positives = 117/188 (62%)
Frame = +3
Query: 3 NDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCF 182
+D++FPA GFGA++PPD ++ HE+PLNG+ ENP C G +G+++AY +L+ V+L GPT F
Sbjct: 375 SDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNF 434
Query: 183 SPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXK 362
+PV+ H++R A A + G Y VLLI+TDG + D +TK+A+V + LP +
Sbjct: 435 APVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAE 494
Query: 363 FSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAEL 542
F M LD D + + A RD VQFV R Y+ D + N S LA+DVLAE+
Sbjct: 495 FDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEI 550
Query: 543 PYQVNEYM 566
P Q+ YM
Sbjct: 551 PDQLVSYM 558
>sp|Q5RAE1|CPNE3_PONPY Copine-3 (Copine III)
Length = 537
Score = 157 bits (396), Expect = 4e-38
Identities = 85/192 (44%), Positives = 118/192 (61%), Gaps = 4/192 (2%)
Frame = +3
Query: 6 DELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCFS 185
D++FPAFGFGA++PP +++ HE+P+N + NPYC G +G+++AY+ L ++KL GPT FS
Sbjct: 339 DKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFS 398
Query: 186 PVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXX 356
P+I H++R A A+ ++ YFVLLI+TDG + D ET++A+V S LP
Sbjct: 399 PIINHVARFAAAAAQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGG 458
Query: 357 XKFSDMETLDQD-FGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVL 533
FS ME LD D GL S E A RD VQFV R++ K ALA+ VL
Sbjct: 459 ADFSAMEFLDGDGGGLRSPSGEVAIRDIVQFVPFRQFQNA----------PKEALAQCVL 508
Query: 534 AELPYQVNEYMH 569
AE+P QV Y +
Sbjct: 509 AEIPQQVVGYFN 520
>sp|Q8BT60|CPNE3_MOUSE Copine-3 (Copine III)
Length = 533
Score = 155 bits (392), Expect = 1e-37
Identities = 84/192 (43%), Positives = 118/192 (61%), Gaps = 4/192 (2%)
Frame = +3
Query: 6 DELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCFS 185
D++FPAFGFGA+VPP +++ HE+P+N + NPYC G +G+++AY+ L +++L GPT FS
Sbjct: 339 DKMFPAFGFGAQVPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRTCLPQIRLYGPTNFS 398
Query: 186 PVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXX 356
P+I H++R A A+ ++ YFVLLI+TDG + D ET++A+V + LP
Sbjct: 399 PIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNAAKLPMSIIIVGVGG 458
Query: 357 XKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVL 533
FS ME LD D G L S E A RD VQFV R++ K ALA+ VL
Sbjct: 459 ADFSAMEFLDGDGGSLRAPSGEVAIRDIVQFVPFRQFQNA----------PKEALAQCVL 508
Query: 534 AELPYQVNEYMH 569
AE+P QV Y +
Sbjct: 509 AEIPQQVVGYFN 520
>sp|O75131|CPNE3_HUMAN Copine-3 (Copine III)
Length = 537
Score = 155 bits (391), Expect = 2e-37
Identities = 84/192 (43%), Positives = 117/192 (60%), Gaps = 4/192 (2%)
Frame = +3
Query: 6 DELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCFS 185
D++FPAFGFGA++PP +++ HE+P+N + NPYC G +G+++AY+ L ++KL GPT FS
Sbjct: 339 DKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGPTNFS 398
Query: 186 PVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXX 356
P+I H++R A A+ ++ YFVLLI+TDG + D ET++A+V S LP
Sbjct: 399 PIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGG 458
Query: 357 XKFSDMETLDQDFGLLMVS-NEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVL 533
FS ME LD D G L E A RD VQFV R++ K ALA+ VL
Sbjct: 459 ADFSAMEFLDGDGGSLRSPLGEVAIRDIVQFVPFRQFQNA----------PKEALAQCVL 508
Query: 534 AELPYQVNEYMH 569
AE+P QV Y +
Sbjct: 509 AEIPQQVVGYFN 520
>sp|Q8C166|CPNE1_MOUSE Copine-1 (Copine I)
Length = 536
Score = 154 bits (389), Expect = 3e-37
Identities = 87/191 (45%), Positives = 114/191 (59%), Gaps = 4/191 (2%)
Frame = +3
Query: 3 NDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCF 182
+D+LFPAFGFGA+VPPD+++ HE+ LN + NPYC G +G++ AY+Q L +V+L GPT F
Sbjct: 331 SDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNF 390
Query: 183 SPVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXX 353
+P+I H++R A + S YFVLL+LTDG+V D T KAVV+ S LP
Sbjct: 391 APIINHVARFAAQAAQQRSASQYFVLLLLTDGAVTDVEATCKAVVDASKLPMSVIIVGVG 450
Query: 354 XXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDV 530
F ME LD D G L S E A RD VQFV RR+ + LA+ V
Sbjct: 451 GADFEVMEQLDADGGPLRTRSGEAAARDIVQFVPYRRFQNApre----------TLAQTV 500
Query: 531 LAELPYQVNEY 563
LAE+P Q+ Y
Sbjct: 501 LAEVPTQMVSY 511
>sp|Q99829|CPNE1_HUMAN Copine-1 (Copine I)
Length = 537
Score = 152 bits (384), Expect = 1e-36
Identities = 86/191 (45%), Positives = 117/191 (61%), Gaps = 4/191 (2%)
Frame = +3
Query: 3 NDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCF 182
+D+LFPAFGFGA+VPPD+++ HE+ LN + NPYC G +G++ AY+Q L +V+L GPT F
Sbjct: 332 SDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNF 391
Query: 183 SPVIRHISRL-AKASESG--KHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXX 353
+P+I H++R A+A+ G YF+LL+LTDG+V D T++AVV S LP
Sbjct: 392 APIINHVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGVG 451
Query: 354 XXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDV 530
F ME LD D G L S + A RD VQFV RR+ + ALA+ V
Sbjct: 452 GADFEAMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNApre----------ALAQTV 501
Query: 531 LAELPYQVNEY 563
LAE+P Q+ Y
Sbjct: 502 LAEVPTQLVSY 512
>sp|Q96FN4|CPNE2_HUMAN Copine-2 (Copine II)
Length = 548
Score = 152 bits (383), Expect = 1e-36
Identities = 82/196 (41%), Positives = 114/196 (58%), Gaps = 4/196 (2%)
Frame = +3
Query: 3 NDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIQAYQQTLKEVKLAGPTCF 182
+D++FPA GFGA++PPD+K+ HE+ +N + NP+C G +G+ QAY L ++ GPT F
Sbjct: 354 SDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNF 413
Query: 183 SPVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXX 353
SP++ H++R A + + YF+LLI+TDG + D ET+ AVV+ S LP
Sbjct: 414 SPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVG 473
Query: 354 XXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDV 530
F+ ME LD D +L + E+A RD VQFV R + A K LAK V
Sbjct: 474 NADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAA----------KETLAKAV 523
Query: 531 LAELPYQVNEYMHRKN 578
LAELP QV +Y KN
Sbjct: 524 LAELPQQVVQYFKHKN 539
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,844,839
Number of Sequences: 369166
Number of extensions: 1886667
Number of successful extensions: 4413
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4254
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4377
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)