Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_M23
(847 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P08928|LAM0_DROME Lamin Dm0 91 3e-18
sp|P13648|LAMA_CHICK Lamin A 80 5e-15
sp|P14732|LAM2_CHICK Lamin B2 75 2e-13
sp|P21910|LAML2_XENLA Lamin L(II) 75 2e-13
sp|P21619|LAM2_MOUSE Lamin B2 74 7e-13
sp|P09010|LAML1_XENLA Lamin L(I) 72 3e-12
sp|P11048|LAMA_XENLA Lamin A 71 4e-12
sp|P11516|LAMC_MOUSE Lamins C and C2 71 4e-12
sp|P48678|LAMA_MOUSE Lamin A 71 4e-12
sp|P02545|LAMA_HUMAN Lamin A/C (70 kDa lamin) 70 6e-12
>sp|P08928|LAM0_DROME Lamin Dm0
Length = 622
Score = 91.3 bits (225), Expect = 3e-18
Identities = 56/176 (31%), Positives = 89/176 (50%), Gaps = 10/176 (5%)
Frame = +1
Query: 1 FSVLNAGSKRRKVGERGEYVASDGKGNVVTSGRD----SFKVDLSGRGNIEFSSKPDCSG 168
FS S R R A K VV D + V S +GN+E + D G
Sbjct: 424 FSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIK-EIDPEG 482
Query: 169 RFVKLINSTDKDLCIGGWTLRYTADKQ--ETTYKFHHNLHVKAKTDCTVWSSDSNETHNP 342
+FV+L N +++ IGGW L+ +++ TTYKFH ++ ++ TVWS+D+ +H P
Sbjct: 483 KFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEP 542
Query: 343 PTDLVMKGQRFFSGVNIKMSLVNSDNQEEASCS----VVKDHTRTSVYNYNRKIAS 498
P+ LVMK Q++ S N + L+NS+ + A+ +V HT +S + R + +
Sbjct: 543 PSSLVMKSQKWVSADNTRTILLNSEGEAVANLDRIKRIVSQHTSSSRLSRRRSVTA 598
>sp|P13648|LAMA_CHICK Lamin A
Length = 657
Score = 80.5 bits (197), Expect = 5e-15
Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 4/150 (2%)
Frame = +1
Query: 13 NAGSKRRKVGERGEYVASDGKGNVVTSGRDSFK--VDLSGRGNIEFSSKPDCSGRFVKLI 186
++G + G + DG+G GR SF SGR +E + D GRFV+L
Sbjct: 400 SSGLQHSGAGSAKKRRLEDGEGREGREGRTSFSHHARTSGRVGVE---EVDLEGRFVRLR 456
Query: 187 NSTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVMK 363
N +++D +G W + R D TY+F +KA T+W+S + TH+PP+D+V K
Sbjct: 457 NKSNEDQALGNWQVKRQNGDDPPLTYRFPPKFTLKAGQAVTIWASGAGATHSPPSDVVWK 516
Query: 364 GQRFF-SGVNIKMSLVNSDNQEEASCSVVK 450
Q + SG +++ +L+NS+ +E A +V+
Sbjct: 517 AQSSWGSGDSLRTALINSNGEEVAMRKLVR 546
>sp|P14732|LAM2_CHICK Lamin B2
Length = 600
Score = 75.5 bits (184), Expect = 2e-13
Identities = 52/151 (34%), Positives = 82/151 (54%), Gaps = 7/151 (4%)
Frame = +1
Query: 19 GSKRRKVGER--GEYVASDGKGNVV-TSGRDSFKVD--LSGRGNIEFSSKPDCSGRFVKL 183
G +RR E G + G G++ +S SF++ S G+I + D G++V+L
Sbjct: 413 GKRRRIEAEELSGSGTSGIGTGSISGSSSSSSFQMSQQASATGSISIE-EIDLEGKYVQL 471
Query: 184 INSTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVM 360
N+++KD +G W L R D +E YKF ++A T+W +D+ +H+PP+ LV
Sbjct: 472 KNNSEKDQSLGNWRLKRQIGDGEEIAYKFTPKYVLRAGQTVTIWGADAGVSHSPPSVLVW 531
Query: 361 KGQ-RFFSGVNIKMSLVNSDNQEEASCSVVK 450
K Q + +G NI+ LVNSD +E A +V K
Sbjct: 532 KNQGSWGTGGNIRTYLVNSDGEEVAVRTVTK 562
>sp|P21910|LAML2_XENLA Lamin L(II)
Length = 623
Score = 75.1 bits (183), Expect = 2e-13
Identities = 48/141 (34%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +1
Query: 61 ASDGKGNVVTSGRDS-----FKVDLSGRGNIEFSSKPDCSGRFVKLINSTDKDLCIGGWT 225
AS+G +TSG+ S S G+I + D G++V L N++DKD +G W
Sbjct: 450 ASEGSSRTITSGQSSTTRFHLSQQASATGSISIE-EIDLEGKYVHLKNNSDKDQSLGNWR 508
Query: 226 L-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVMKGQRFF-SGVNIKM 399
L R +++E YKF +KA ++S+D+ H+PP+ LV K Q + +G NI+
Sbjct: 509 LKRKIGEEEEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSILVWKNQSSWGTGSNIRT 568
Query: 400 SLVNSDNQEEASCSVVKDHTR 462
LVN++ +E A +V K R
Sbjct: 569 YLVNTEEEEVAVRTVTKSVLR 589
>sp|P21619|LAM2_MOUSE Lamin B2
Length = 592
Score = 73.6 bits (179), Expect = 7e-13
Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = +1
Query: 4 SVLNAGSKRRKVGERGEYVASDGKGNVVTSGRDSFKVDLSGRGNIEFSSKPDCSGRFVKL 183
SV G KRR++ + S + + V+SG + +G NI+ + D GRFV+L
Sbjct: 407 SVGQRGGKRRRLEDTS---GSPSRASRVSSGSRLAQTVATGVVNID---EVDPEGRFVRL 460
Query: 184 INSTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVM 360
NS+DKD +G W + R + ++ YKF ++A TVW++ + TH+PP+ LV
Sbjct: 461 KNSSDKDQSLGNWRIKRQVLEGEDIAYKFTPKYVLRAGQTVTVWAAGAGATHSPPSTLVW 520
Query: 361 KGQ-RFFSGVNIKMSLVNSDNQEEA 432
K Q + G + + +LV++D +E A
Sbjct: 521 KSQTNWGPGESFRTALVSADGEEVA 545
>sp|P09010|LAML1_XENLA Lamin L(I)
Length = 583
Score = 71.6 bits (174), Expect = 3e-12
Identities = 50/175 (28%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = +1
Query: 4 SVLNAGSKRRKVGERGEYVASDGKGNVVTSGRDSFKVDLSGRGNIEFS-SKPDCSGRFVK 180
+V A S R +G+ D + + +S S +D S + S + D G++++
Sbjct: 398 TVSRASSSRAVRTTKGKRKRIDVEESEASS---SVSIDHSAAATGDVSIEEVDVDGKYIR 454
Query: 181 LINSTDKDLCIGGWTLRYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVM 360
L N+++KD +GGW L T + +KF +KA+ T+W++D+ +PP+DL+
Sbjct: 455 LKNNSEKDHPLGGWELTRTIGEASVNFKFTSRYVLKAEQTVTIWAADAGVKASPPSDLIW 514
Query: 361 KGQRFF-SGVNIKMSLVNSDNQEEASCSVVKDHTRTSVYNYNRKIASRSVRTGEE 522
K Q + +G ++K +L NS +E A RT++Y N I GEE
Sbjct: 515 KNQNSWGTGEDVKATLKNSQGEEVAQ--------RTTIYTTN--IPEEEFEEGEE 559
>sp|P11048|LAMA_XENLA Lamin A
Length = 665
Score = 70.9 bits (172), Expect = 4e-12
Identities = 46/150 (30%), Positives = 82/150 (54%), Gaps = 2/150 (1%)
Frame = +1
Query: 7 VLNAGSKRRKVGERGEYVASDGKGNVVTSGRDSFKVDLSGRGNIEFSSKPDCSGRFVKLI 186
+ ++ SKRR++ E GE +S + T+G+ S + + D G++V+L
Sbjct: 407 ISSSASKRRRL-EEGESRSSSFTQHARTTGKVSVE-------------EVDPEGKYVRLR 452
Query: 187 NSTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVMK 363
N +++D +G W + R D+ YKF L +KA T+W+S + T++PP+DLV K
Sbjct: 453 NKSNEDQSLGNWQIKRQIGDETPIVYKFPPRLTLKAGQTVTIWASGAGATNSPPSDLVWK 512
Query: 364 GQRFF-SGVNIKMSLVNSDNQEEASCSVVK 450
Q + +G +I+ +L+ S N+E A +V+
Sbjct: 513 AQSSWGTGDSIRTALLTSSNEEVAMRKLVR 542
>sp|P11516|LAMC_MOUSE Lamins C and C2
Length = 574
Score = 70.9 bits (172), Expect = 4e-12
Identities = 48/143 (33%), Positives = 74/143 (51%), Gaps = 11/143 (7%)
Frame = +1
Query: 64 SDGKGNVV-------TSGRDSFK--VDLSGRGNIEFSSKPDCSGRFVKLINSTDKDLCIG 216
S G G+V + R SF SGR +E + D G+FV+L N +++D +G
Sbjct: 409 SQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVE---EVDEEGKFVRLRNKSNEDQSMG 465
Query: 217 GWTLR-YTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVMKGQRFFS-GVN 390
W +R D TY+F +KA T+W+S + TH+PPTDLV K Q + G +
Sbjct: 466 NWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSS 525
Query: 391 IKMSLVNSDNQEEASCSVVKDHT 459
++ +L+NS +E A +V+ T
Sbjct: 526 LRTALINSTGEEVAMRKLVRSLT 548
>sp|P48678|LAMA_MOUSE Lamin A
Length = 665
Score = 70.9 bits (172), Expect = 4e-12
Identities = 48/143 (33%), Positives = 74/143 (51%), Gaps = 11/143 (7%)
Frame = +1
Query: 64 SDGKGNVV-------TSGRDSFK--VDLSGRGNIEFSSKPDCSGRFVKLINSTDKDLCIG 216
S G G+V + R SF SGR +E + D G+FV+L N +++D +G
Sbjct: 409 SQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVE---EVDEEGKFVRLRNKSNEDQSMG 465
Query: 217 GWTLR-YTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVMKGQRFFS-GVN 390
W +R D TY+F +KA T+W+S + TH+PPTDLV K Q + G +
Sbjct: 466 NWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSS 525
Query: 391 IKMSLVNSDNQEEASCSVVKDHT 459
++ +L+NS +E A +V+ T
Sbjct: 526 LRTALINSTGEEVAMRKLVRSLT 548
>sp|P02545|LAMA_HUMAN Lamin A/C (70 kDa lamin)
Length = 664
Score = 70.5 bits (171), Expect = 6e-12
Identities = 44/128 (34%), Positives = 69/128 (53%), Gaps = 4/128 (3%)
Frame = +1
Query: 88 TSGRDSFK--VDLSGRGNIEFSSKPDCSGRFVKLINSTDKDLCIGGWTL-RYTADKQETT 258
T R SF SGR +E + D G+FV+L N +++D +G W + R D T
Sbjct: 424 TESRSSFSQHARTSGRVAVE---EVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLT 480
Query: 259 YKFHHNLHVKAKTDCTVWSSDSNETHNPPTDLVMKGQRFFS-GVNIKMSLVNSDNQEEAS 435
Y+F +KA T+W++ + TH+PPTDLV K Q + G +++ +L+NS +E A
Sbjct: 481 YRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAM 540
Query: 436 CSVVKDHT 459
+V+ T
Sbjct: 541 RKLVRSVT 548
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,202,830
Number of Sequences: 369166
Number of extensions: 1870045
Number of successful extensions: 5095
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4709
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5073
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)