Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_M20
(892 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9DGM7|MVP_ICTPU Major vault protein (MVP) 285 9e-77
sp|Q14764|MVP_HUMAN Major vault protein (MVP) (Lung resista... 285 2e-76
sp|Q90405|MVP_DISOM Major vault protein (MVP100) (P100) 283 3e-76
sp|Q9EQK5|MVP_MOUSE Major vault protein (MVP) 282 1e-75
sp|Q62667|MVP_RAT Major vault protein (MVP) 281 2e-75
sp|P34118|MVPA_DICDI Major vault protein alpha (MVP-alpha) 275 2e-73
sp|P54659|MVPB_DICDI Major vault protein beta (MVP-beta) 228 2e-59
sp|P19934|TOLA_ECOLI Protein tolA 59 1e-08
sp|P30427|PLEC1_RAT Plectin 1 (PLTN) (PCN) 52 2e-06
sp|Q9JI55|PLEC1_CRIGR Plectin 1 (PLTN) (PCN) (300-kDa inter... 52 2e-06
>sp|Q9DGM7|MVP_ICTPU Major vault protein (MVP)
Length = 871
Score = 285 bits (730), Expect = 9e-77
Identities = 152/241 (63%), Positives = 189/241 (78%)
Frame = +3
Query: 3 IRSSVFGVDANNKVREEFVFPQNNLCITSIDIQSVEPVDQRTRESLQKSVQLAIEITTKS 182
I S+VFG D VR F QN L I+S+DIQSVEPVDQRTR++LQKSVQLAIEITT S
Sbjct: 624 ICSAVFGFDEKLAVRSSLRFNQNGLVISSVDIQSVEPVDQRTRDALQKSVQLAIEITTNS 683
Query: 183 QEASARHEADRIEQQAKGRLERQMITDQAEAERTRTELLQLRAASAAVESTGQAKAEAQS 362
QEA+ARHEA+R+EQ+A+G+LERQ ITDQAEAER R ELL+L A SAAVESTG AKAEAQS
Sbjct: 684 QEATARHEAERLEQEARGKLERQKITDQAEAERARKELLELEALSAAVESTGAAKAEAQS 743
Query: 363 RAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNEVAETHTQKMA 542
RAEA+RI+GEA V++AKLK EA IEAE E+ R+ AR E+ Y ++ + + QK+
Sbjct: 744 RAEAARIQGEAAVQEAKLKVEALRIEAEAEMVRLAKAREQELLYKKELDHLEVEKQQKLV 803
Query: 543 DIEIYKFSKMVEAIGPNTLIEIAKAGPDGDVRLLQSMGLKSALITDGSTPINLFQTAHGL 722
IE +F ++VEAIG TL +A+AGP+ V++LQ++GLKS LITDGS+PINLF TA+GL
Sbjct: 804 TIESQRFKQLVEAIGSETLTAMARAGPELQVKMLQALGLKSTLITDGSSPINLFTTANGL 863
Query: 723 I 725
+
Sbjct: 864 L 864
>sp|Q14764|MVP_HUMAN Major vault protein (MVP) (Lung resistance-related protein)
Length = 893
Score = 285 bits (728), Expect = 2e-76
Identities = 149/251 (59%), Positives = 194/251 (77%), Gaps = 10/251 (3%)
Frame = +3
Query: 3 IRSSVFGVDANN----------KVREEFVFPQNNLCITSIDIQSVEPVDQRTRESLQKSV 152
IR++VFG + + + R++ VFPQN L ++S+D+QSVEPVDQRTR++LQ+SV
Sbjct: 599 IRTAVFGFETSEAKGPDGMALPRPRDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSV 658
Query: 153 QLAIEITTKSQEASARHEADRIEQQAKGRLERQMITDQAEAERTRTELLQLRAASAAVES 332
QLAIEITT SQEA+A+HEA R+EQ+A+GRLERQ I DQ+EAE+ R ELL+L A S AVES
Sbjct: 659 QLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEALSMAVES 718
Query: 333 TGQAKAEAQSRAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNE 512
TG AKAEA+SRAEA+RIEGE +V QAKLKA+A IE E EL RV R E+ Y++ E
Sbjct: 719 TGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELQRVQKVRELELVYARAQLE 778
Query: 513 VAETHTQKMADIEIYKFSKMVEAIGPNTLIEIAKAGPDGDVRLLQSMGLKSALITDGSTP 692
+ + Q++A++E+ KF +M EAIGP+T+ ++A AGP+ V+LLQS+GLKS LITDGSTP
Sbjct: 779 LEVSKAQQLAEVEVKKFKQMTEAIGPSTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSTP 838
Query: 693 INLFQTAHGLI 725
INLF TA GL+
Sbjct: 839 INLFNTAFGLL 849
>sp|Q90405|MVP_DISOM Major vault protein (MVP100) (P100)
Length = 852
Score = 283 bits (725), Expect = 3e-76
Identities = 145/241 (60%), Positives = 190/241 (78%)
Frame = +3
Query: 3 IRSSVFGVDANNKVREEFVFPQNNLCITSIDIQSVEPVDQRTRESLQKSVQLAIEITTKS 182
+R++VFG+D +VRE +FPQN+LC+TS+D+ SVEPVDQRTR++LQ+SVQLAIEITTKS
Sbjct: 599 LRAAVFGLDPELRVRERLLFPQNSLCVTSVDVHSVEPVDQRTRDALQRSVQLAIEITTKS 658
Query: 183 QEASARHEADRIEQQAKGRLERQMITDQAEAERTRTELLQLRAASAAVESTGQAKAEAQS 362
QEA+AR EA R+EQ+AKGRLERQ I DQAE+ER R ELL L A S AVES G A+AEA+S
Sbjct: 659 QEAAARQEAARLEQEAKGRLERQRILDQAESERARRELLLLEADSTAVESRGAARAEAES 718
Query: 363 RAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNEVAETHTQKMA 542
RAEASRIEGE +V QAKLKA+A IE E EL R+ AR E++Y + N + T++++
Sbjct: 719 RAEASRIEGEGSVLQAKLKAQALDIETEAELERLTKARERELKYIAEQNRLEVEKTRQLS 778
Query: 543 DIEIYKFSKMVEAIGPNTLIEIAKAGPDGDVRLLQSMGLKSALITDGSTPINLFQTAHGL 722
++E +F +MV+AIG +T+ IA++GP+ V+LLQ +GL S LITDGSTP+NLF A G+
Sbjct: 779 ELESRRFQEMVQAIGADTIRAIAESGPELQVKLLQGLGLNSTLITDGSTPVNLFSAAKGM 838
Query: 723 I 725
+
Sbjct: 839 L 839
>sp|Q9EQK5|MVP_MOUSE Major vault protein (MVP)
Length = 861
Score = 282 bits (721), Expect = 1e-75
Identities = 149/251 (59%), Positives = 190/251 (75%), Gaps = 10/251 (3%)
Frame = +3
Query: 3 IRSSVFGVDANN----------KVREEFVFPQNNLCITSIDIQSVEPVDQRTRESLQKSV 152
IR +VFG + + + R+ VFPQN L ++S+D+QSVEPVDQRTR++LQ+SV
Sbjct: 599 IRMAVFGFEMSEDAGPDGALLPRARDRAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSV 658
Query: 153 QLAIEITTKSQEASARHEADRIEQQAKGRLERQMITDQAEAERTRTELLQLRAASAAVES 332
QLAIEITT SQEA+A+HEA R+EQ+A+GRLERQ I DQ+EAE+ R ELL+L A S AVES
Sbjct: 659 QLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVES 718
Query: 333 TGQAKAEAQSRAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNE 512
TG AKAEA+SRAEA+RIEGE +V QAKLKA+A IE E EL RV R E+ YS+ E
Sbjct: 719 TGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELIYSRAQLE 778
Query: 513 VAETHTQKMADIEIYKFSKMVEAIGPNTLIEIAKAGPDGDVRLLQSMGLKSALITDGSTP 692
+ + Q++AD+E KF +M EA+GP T+ ++A AGP+ V+LLQS+GLKS LITDGS+P
Sbjct: 779 LEVSKAQQLADVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSSP 838
Query: 693 INLFQTAHGLI 725
INLF TA GL+
Sbjct: 839 INLFNTAFGLL 849
>sp|Q62667|MVP_RAT Major vault protein (MVP)
Length = 861
Score = 281 bits (718), Expect = 2e-75
Identities = 148/251 (58%), Positives = 191/251 (76%), Gaps = 10/251 (3%)
Frame = +3
Query: 3 IRSSVFGVDANN----------KVREEFVFPQNNLCITSIDIQSVEPVDQRTRESLQKSV 152
IR +VFG + + K R++ VFPQN L ++S+D+QSVEPVDQRTR++LQ+SV
Sbjct: 599 IRMAVFGFEMSEDTGPDGTLLPKARDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSV 658
Query: 153 QLAIEITTKSQEASARHEADRIEQQAKGRLERQMITDQAEAERTRTELLQLRAASAAVES 332
QLAIEITT SQEA+A+HEA R+EQ+A+GRLERQ I DQ+EAE+ R ELL+L A S AVES
Sbjct: 659 QLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVES 718
Query: 333 TGQAKAEAQSRAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNE 512
TG AKAEA+SRAEA+RIEGE +V QAKLKA+A IE E EL RV R E+ Y++ E
Sbjct: 719 TGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELIYARAQLE 778
Query: 513 VAETHTQKMADIEIYKFSKMVEAIGPNTLIEIAKAGPDGDVRLLQSMGLKSALITDGSTP 692
+ + Q++A++E KF +M EA+GP T+ ++A AGP+ V+LLQS+GLKS LITDGS+P
Sbjct: 779 LEVSKAQQLANVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSSP 838
Query: 693 INLFQTAHGLI 725
INLF TA GL+
Sbjct: 839 INLFSTAFGLL 849
>sp|P34118|MVPA_DICDI Major vault protein alpha (MVP-alpha)
Length = 843
Score = 275 bits (702), Expect = 2e-73
Identities = 147/241 (60%), Positives = 188/241 (78%)
Frame = +3
Query: 3 IRSSVFGVDANNKVREEFVFPQNNLCITSIDIQSVEPVDQRTRESLQKSVQLAIEITTKS 182
IR SVFG+D + +VR+ F F NNL IT+IDIQSVEPVDQRTR+SLQKSVQLAIEITTKS
Sbjct: 583 IRQSVFGLDESGEVRKNFSFNSNNLVITNIDIQSVEPVDQRTRDSLQKSVQLAIEITTKS 642
Query: 183 QEASARHEADRIEQQAKGRLERQMITDQAEAERTRTELLQLRAASAAVESTGQAKAEAQS 362
QEA+ARHEA+R+EQ A+GRLERQ I D+A+AE R +LLQL+A SAAVESTGQA AEAQ+
Sbjct: 643 QEAAARHEAERLEQGARGRLERQKIHDEAQAELARKDLLQLQAQSAAVESTGQATAEAQA 702
Query: 363 RAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNEVAETHTQKMA 542
AEA+ I EANV+QA+LKA+AT I +E+E++ + A R E+ Y + +E+ T +A
Sbjct: 703 TAEAANIAAEANVKQAELKAQATKIRSESEISLLKAKRENELSYQKSIDELELTKQSDLA 762
Query: 543 DIEIYKFSKMVEAIGPNTLIEIAKAGPDGDVRLLQSMGLKSALITDGSTPINLFQTAHGL 722
+IE KF +VE+IG +TL IA AG + +LLQ +GLKS +ITDG +P+NLF TA+G+
Sbjct: 763 EIEASKFKAIVESIGRDTLKSIACAGNEMQAKLLQGLGLKSFMITDGKSPLNLFDTANGI 822
Query: 723 I 725
I
Sbjct: 823 I 823
>sp|P54659|MVPB_DICDI Major vault protein beta (MVP-beta)
Length = 846
Score = 228 bits (580), Expect = 2e-59
Identities = 126/241 (52%), Positives = 171/241 (70%)
Frame = +3
Query: 3 IRSSVFGVDANNKVREEFVFPQNNLCITSIDIQSVEPVDQRTRESLQKSVQLAIEITTKS 182
I+ +VFG + + F N L IT+ID+QSVEPVDQRT +SLQKSVQLAIEITTKS
Sbjct: 596 IQQAVFG-STDGSSNDCLYFETNGLVITNIDVQSVEPVDQRTLDSLQKSVQLAIEITTKS 654
Query: 183 QEASARHEADRIEQQAKGRLERQMITDQAEAERTRTELLQLRAASAAVESTGQAKAEAQS 362
QEA+AR EA+R+EQ A+G LERQ I D+A+ E +R++L+QL+A SAAVESTGQA AEA++
Sbjct: 655 QEATARQEAERLEQMARGELERQKIIDEAKNEESRSKLVQLQAQSAAVESTGQAVAEARA 714
Query: 363 RAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNEVAETHTQKMA 542
RAEA+ IE E+ ++QA+L A IEA +E+ + A EI++ + N + ++ A
Sbjct: 715 RAEAAIIEAESEIKQARLSTRAIEIEALSEIENLKAKHIVEIQHIKSLNNLELIKAKESA 774
Query: 543 DIEIYKFSKMVEAIGPNTLIEIAKAGPDGDVRLLQSMGLKSALITDGSTPINLFQTAHGL 722
IE KF VEA+G +T+ IA+A + +LL +GLKS +ITDG +P+NLF TA+GL
Sbjct: 775 TIETTKFENYVEALGSDTIKSIAQAPEETKAKLLAGLGLKSFMITDGKSPLNLFDTANGL 834
Query: 723 I 725
I
Sbjct: 835 I 835
>sp|P19934|TOLA_ECOLI Protein tolA
Length = 421
Score = 59.3 bits (142), Expect = 1e-08
Identities = 48/158 (30%), Positives = 74/158 (46%)
Frame = +3
Query: 96 IQSVEPVDQRTRESLQKSVQLAIEITTKSQEASARHEADRIEQQAKGRLERQMITDQAEA 275
+QS E +R+ E + Q A E + Q A E +R++Q K RL Q QAE
Sbjct: 67 MQSQESSAKRSDEQRKMKEQQAAEELREKQAA----EQERLKQLEKERLAAQEQKKQAEE 122
Query: 276 ERTRTELLQLRAASAAVESTGQAKAEAQSRAEASRIEGEANVEQAKLKAEATTIEAENEL 455
+ EL Q +A AA ++ AKA+A++ A+A+ + AK KAEA +A E
Sbjct: 123 AAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAAEA 182
Query: 456 ARVIAARNAEIEYSQKHNEVAETHTQKMADIEIYKFSK 569
+ A A ++ + E A +K A E + +K
Sbjct: 183 QKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAK 220
>sp|P30427|PLEC1_RAT Plectin 1 (PLTN) (PCN)
Length = 4687
Score = 52.0 bits (123), Expect = 2e-06
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 17/169 (10%)
Frame = +3
Query: 96 IQSVEPVDQRTRESLQKSVQLAIEITTKSQEASARHEADRIEQQAKGRLERQMITDQAEA 275
++ + +R + + +QLA E K +A + A + QQ + L++ + +Q
Sbjct: 2158 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAF-VVQQREEELQQTLQQEQNML 2216
Query: 276 ERTRTEL-LQLRAASAAVESTGQAKAEA-QSRA---EASRIEGEANVE-----QAKLKAE 425
ER R+E RAA A E+ QA+ EA QSR EA R++ A + QA+ AE
Sbjct: 2217 ERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAE 2276
Query: 426 ATTIEAENELARVIAARNAEIEYSQ-------KHNEVAETHTQKMADIE 551
EAE E AR A A ++ Q KH + AE ++ A +E
Sbjct: 2277 KLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVE 2325
Score = 43.1 bits (100), Expect = 0.001
Identities = 45/167 (26%), Positives = 70/167 (41%), Gaps = 18/167 (10%)
Frame = +3
Query: 114 VDQRTRESLQKSVQLAIEITTKSQEASARHEA----DRIEQQAKGRLERQMITDQAEAER 281
V ++ Q +LA+ + +++ A + A D ++ QA+ E + QAEAER
Sbjct: 1643 VQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAE---EAERWLCQAEAER 1699
Query: 282 TRTELLQLRAA--SAAVESTGQAKAEAQSRAEASRIEGEANVEQAKLKAEA--------- 428
R + L A SA VE + + A+ A+ R E +V +L+ EA
Sbjct: 1700 ARQVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAE 1759
Query: 429 ---TTIEAENELARVIAARNAEIEYSQKHNEVAETHTQKMADIEIYK 560
EAE EL R N + + EVA+ + AD E K
Sbjct: 1760 AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQK 1806
Score = 37.4 bits (85), Expect = 0.057
Identities = 46/175 (26%), Positives = 79/175 (45%), Gaps = 12/175 (6%)
Frame = +3
Query: 123 RTRESLQKSVQLAIEIT--TKSQEASARHEADRIEQQAK-GRLERQMITD-----QAEAE 278
R RE ++ ++ ++T T Q +A E R+ + + G +RQ++ + Q EA
Sbjct: 1825 RQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELARLQHEAT 1884
Query: 279 RTRTELLQLRAASAAVESTGQAKAEAQSRAEASRIEGEANVEQAKLKAEATTIEAENELA 458
+ +L A A V + + +++RAE E + E++K + EA ELA
Sbjct: 1885 AATQKRQELEAELAKVRAEMEVLLASKARAEE---ESRSTSEKSKQRLEAEAGRFR-ELA 1940
Query: 459 RVIAARNAEIEYSQKHNEVAETHTQKM---AD-IEIYKFSKMVEAIGPNTLIEIA 611
A A E +++H E+AE + AD + K + + EA T EIA
Sbjct: 1941 EEAARLRALAEEARRHRELAEEDAARQRAEADGVLTEKLAAISEATRLKTEAEIA 1995
Score = 36.2 bits (82), Expect = 0.13
Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 10/136 (7%)
Frame = +3
Query: 99 QSVEPVDQRTRESLQKSVQLAIE-ITTKSQEASARHEADRIEQQAKGRLERQMITDQAEA 275
Q +E Q T + Q+ + E I +++ H+ +E++ RL+ + +
Sbjct: 1832 QELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEEL-ARLQHEATAATQKR 1890
Query: 276 ERTRTELLQLRAA-SAAVESTGQAKAEAQSRAEAS--RIEGEAN------VEQAKLKAEA 428
+ EL ++RA + S +A+ E++S +E S R+E EA E A+L+A A
Sbjct: 1891 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1950
Query: 429 TTIEAENELARVIAAR 476
ELA AAR
Sbjct: 1951 EEARRHRELAEEDAAR 1966
Score = 35.0 bits (79), Expect = 0.28
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 2/163 (1%)
Frame = +3
Query: 99 QSVEPVDQRTRESLQKSVQLAIEITTKSQEASARHEADRIEQQAKGRLER-QMITDQAEA 275
+ ++ V + TR L+ +L + +QE + R +AD+ EQ A+ +E Q EA
Sbjct: 2454 EKMQAVQEATR--LKAEAELLQQQKELAQEQARRLQADK-EQMAQQLVEETQGFQRTLEA 2510
Query: 276 ERTRTELLQLRAASAAVESTGQAKAEAQSRAEASRIEGEANVEQAKL-KAEATTIEAENE 452
ER R + A + ++A+A++ +A R +A KL + E T E
Sbjct: 2511 ERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE---- 2566
Query: 453 LARVIAARNAEIEYSQKHNEVAETHTQKMADIEIYKFSKMVEA 581
+V + EI+ Q+ ++ AE + +A++E K EA
Sbjct: 2567 --KVTLVQTLEIQ-RQQSDQDAERLREAIAELEREKEKLKQEA 2606
Score = 31.6 bits (70), Expect = 3.1
Identities = 31/130 (23%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Frame = +3
Query: 183 QEASARHEAD------RIEQQAKGRLERQ--MITDQAEAERTRTELLQLRAASAAVESTG 338
+E +A+H+AD ++ + ++ LERQ ++ D R E ++ A A+ E
Sbjct: 2021 EEQAAQHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEE--EIMALKASFEKAA 2078
Query: 339 QAKAEAQSRAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARNAEI--EYSQKHNE 512
KAE + +E ++++ A ELA AAR ++ E Q+ E
Sbjct: 2079 AGKAELE-------------LELGRIRSNAEDTMRSKELAEQEAARQRQLAAEEEQRRRE 2125
Query: 513 VAETHTQKMA 542
E + +A
Sbjct: 2126 AEERVQRSLA 2135
>sp|Q9JI55|PLEC1_CRIGR Plectin 1 (PLTN) (PCN) (300-kDa intermediate filament-associated
protein) (IFAP300)
Length = 4473
Score = 52.0 bits (123), Expect = 2e-06
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 17/169 (10%)
Frame = +3
Query: 96 IQSVEPVDQRTRESLQKSVQLAIEITTKSQEASARHEADRIEQQAKGRLERQMITDQAEA 275
++ + +R + + +QLA E K +A + A + QQ + L++ + +Q+
Sbjct: 1944 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAF-VVQQREEELQQTLQQEQSML 2002
Query: 276 ERTRTEL-LQLRAASAAVESTGQAKAEA-QSRA---EASRIEGEANVE-----QAKLKAE 425
ER R E RAA A E+ QA+ EA QSR EA R++ A + QA+ AE
Sbjct: 2003 ERLRGEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQARAQAQAAAE 2062
Query: 426 ATTIEAENELARVIAARNAEIEYSQ-------KHNEVAETHTQKMADIE 551
EAE E AR A A ++ Q KH + AE ++ A +E
Sbjct: 2063 KLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVE 2111
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/164 (25%), Positives = 67/164 (40%), Gaps = 15/164 (9%)
Frame = +3
Query: 114 VDQRTRESLQKSVQLAIEITTKSQEASARHEA-DRIEQQAKGRLERQMITDQAEAERTRT 290
V ++ Q +LA+ + +++ A + A +E+ E + QA+AER R
Sbjct: 1429 VQDESQRKRQAEAELALRVKAQAEAAQEKQRALQALEELRLQAEEAERRLRQAQAERARQ 1488
Query: 291 ELLQLRAA--SAAVESTGQAKAEAQSRAEASRIEGEANVEQAKLK------------AEA 428
+ L A SA VE + + A+ A+ R E +V +L+ AE
Sbjct: 1489 VQVALETAQRSAEVELQSKRASFAEKTAQLERTLQEEHVTVTQLREKAERRAQQQAEAER 1548
Query: 429 TTIEAENELARVIAARNAEIEYSQKHNEVAETHTQKMADIEIYK 560
EAE EL R N + + EVA+ + AD E K
Sbjct: 1549 AREEAERELERWQLKANEALRLRLQAEEVAQQRSLAQADAEKQK 1592
Score = 34.3 bits (77), Expect = 0.48
Identities = 33/154 (21%), Positives = 67/154 (43%), Gaps = 4/154 (2%)
Frame = +3
Query: 132 ESLQKSVQLAIEITTKSQEASARHEADRIEQQAKGRLERQMITDQAEAERT----RTELL 299
+++Q++ +L E Q+ E R Q+ K ++ +Q++ + +RT R L
Sbjct: 2243 QAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLVEETQGFQRTLEVERQRQL 2302
Query: 300 QLRAASAAVESTGQAKAEAQSRAEASRIEGEANVEQAKLKAEATTIEAENELARVIAARN 479
++ A + ++ + AQ+RAE E+ K T + + +V +
Sbjct: 2303 EMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQE---KVTLVQT 2359
Query: 480 AEIEYSQKHNEVAETHTQKMADIEIYKFSKMVEA 581
EI+ Q ++ AE + +A++E K EA
Sbjct: 2360 LEIQRQQSDHD-AERLREAIAELEREKEKLKQEA 2392
Score = 32.0 bits (71), Expect = 2.4
Identities = 46/187 (24%), Positives = 84/187 (44%), Gaps = 30/187 (16%)
Frame = +3
Query: 81 ITSIDIQSVEPVDQRT--RESLQKSVQLAIEITTKSQEASARHE---ADRIEQQAKGRLE 245
+T++ +Q E Q++ E LQ+ L E+T +++ S E + R++ + G+L+
Sbjct: 2114 LTTLRLQLEETDHQKSILDEELQR---LKAEVTEAARQRSQVEEELFSVRVQMEELGKLK 2170
Query: 246 RQMITD----------------QAEAERTRTELLQLRAASAAVESTGQAK--AE---AQS 362
++ + + EAE+ + + S A + + + AE AQ
Sbjct: 2171 ARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2230
Query: 363 RAEASRIEGE---ANVEQAKLKAEATTIEAENELARVIAARNAEIEYSQKHNEVAETH-T 530
RA A ++ E A E +LKAEA ++ + ELA+ A R E + V ET
Sbjct: 2231 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLVEETQGF 2290
Query: 531 QKMADIE 551
Q+ ++E
Sbjct: 2291 QRTLEVE 2297
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,426,096
Number of Sequences: 369166
Number of extensions: 1422136
Number of successful extensions: 4633
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4298
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4558
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)