Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_L18
(817 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9MYP6|DHR10_BOVIN Dehydrogenase/reductase SDR family me... 194 2e-49
sp|Q9BPX1|DHR10_HUMAN Dehydrogenase/reductase SDR family me... 192 9e-49
sp|Q8KWT4|BACC2_BACSU Bacilysin biosynthesis oxidoreductase... 138 2e-32
sp|P39640|BACC_BACSU Bacilysin biosynthesis oxidoreductase ... 132 9e-31
sp|Q9WYG0|Y325_THEMA Hypothetical oxidoreductase TM0325 130 6e-30
sp|P46331|YXBG_BACSU Hypothetical oxidoreductase yxbG 126 6e-29
sp|P50198|LINX_PSEPA 2,5-dichloro-2,5-cyclohexadiene-1,4-di... 126 8e-29
sp|Q9X248|FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] reduc... 124 3e-28
sp|P50160|TS2_MAIZE Sex determination protein tasselseed 2 121 2e-27
sp|Q8KWS9|BACC_BACAM Bacilysin biosynthesis oxidoreductase ... 117 3e-26
>sp|Q9MYP6|DHR10_BOVIN Dehydrogenase/reductase SDR family member 10 (Retinal short-chain
dehydrogenase/reductase retSDR3)
Length = 270
Score = 194 bits (493), Expect = 2e-49
Identities = 112/263 (42%), Positives = 158/263 (60%), Gaps = 5/263 (1%)
Frame = +1
Query: 7 FDNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELSGRNVIFLFCNVT 186
+ K++++ GG GIGA V+ F + A VV C D+ G + EL G +FL C+VT
Sbjct: 7 YAGKVVIVTGGGRGIGAGIVRAFVESGAQVVICDKDEARGRAVERELPG--TVFLLCDVT 64
Query: 187 IEDDIKSVINHIENIHG-GKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHFLFC 363
E+D++++++ E I G+LDC++NN G HP + +N+ +
Sbjct: 65 REEDVRTLVS--ETIRRFGRLDCIVNNAGYHPPPQWPEETSAQGFRQLLELNLLGTYTLT 122
Query: 364 KYSMPMLRKYRGCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVRVNCI 543
K ++P LRK RG +IN+SS VG IGQ AV Y TKGA+TAMTK+LALDE++YGVRVNCI
Sbjct: 123 KLALPHLRKSRGNVINISSLVGAIGQSQAVPYVATKGAVTAMTKALALDESQYGVRVNCI 182
Query: 544 SPGIINTPL---LVQNTID-NCRLKGGLSYESEIDKMKKLIPLGDLGDPIDVAHACMFLA 711
SPG I TPL L +T D ++ G + PLG +G P +VA A +FLA
Sbjct: 183 SPGNIWTPLWEELAASTPDPTATIREGTLAQ----------PLGRMGQPAEVAAAAVFLA 232
Query: 712 SDMAKHITGSDIPVSGGAEIGYG 780
S+ A TG+++ V+GGAE+GYG
Sbjct: 233 SE-ATFCTGTELLVTGGAELGYG 254
>sp|Q9BPX1|DHR10_HUMAN Dehydrogenase/reductase SDR family member 10 (Retinal short-chain
dehydrogenase/reductase retSDR3)
Length = 270
Score = 192 bits (488), Expect = 9e-49
Identities = 109/263 (41%), Positives = 155/263 (58%), Gaps = 5/263 (1%)
Frame = +1
Query: 7 FDNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELSGRNVIFLFCNVT 186
+ K++++ GG GIGA V+ F ++ A VV C D+ G L EL G +F+ C+VT
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--AVFILCDVT 64
Query: 187 IEDDIKSVINHIENIHG-GKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHFLFC 363
EDD+K++++ E I G+LDC++NN G HP ++ +N+ +
Sbjct: 65 QEDDVKTLVS--ETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 364 KYSMPMLRKYRGCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVRVNCI 543
K ++P LRK +G +IN+SS VG IGQ AV Y TKGA+TAMTK+LALDE+ YGVRVNCI
Sbjct: 123 KLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182
Query: 544 SPGIINTPLLVQNTI----DNCRLKGGLSYESEIDKMKKLIPLGDLGDPIDVAHACMFLA 711
SPG I TPL + ++ G+ + PLG +G P +V A +FLA
Sbjct: 183 SPGNIWTPLWEELAALMPDPRATIREGMLAQ----------PLGRMGQPAEVGAAAVFLA 232
Query: 712 SDMAKHITGSDIPVSGGAEIGYG 780
S+ A TG ++ V+GGAE+GYG
Sbjct: 233 SE-ANFCTGIELLVTGGAELGYG 254
>sp|Q8KWT4|BACC2_BACSU Bacilysin biosynthesis oxidoreductase bacC
Length = 253
Score = 138 bits (347), Expect = 2e-32
Identities = 90/256 (35%), Positives = 140/256 (54%), Gaps = 2/256 (0%)
Frame = +1
Query: 1 MNFDNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELSGRNVIFLFCN 180
MN +K +LI GG SGIG A V+ F + A VV D+ G ++ + + + F+ +
Sbjct: 1 MNLTDKTVLITGGASGIGYAAVQAFLNQQANVVVADIDEAQGEAMIRKENNDRLHFVHTD 60
Query: 181 VTIEDDIKSVINHIENIHGGKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHFLF 360
+T E ++ I + GG LD LINN G I N+N+ FL
Sbjct: 61 ITDEPACQNAIRSAVDKFGG-LDVLINNAGIEIV-APIHEMELSNWNKVLNVNLTGMFLM 118
Query: 361 CKYSMP-MLRKYRGCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVRVN 537
K+++ ML+ +G IIN S G + + Y +KG + +T+S+A+D A++ +RVN
Sbjct: 119 SKHALKYMLKSGKGNIINTCSVGGVVAWPDIPAYNASKGGVLQLTRSMAVDYAKHNIRVN 178
Query: 538 CISPGIINTPLLVQNTIDNCRLKGGLSYESEIDKMK-KLIPLGDLGDPIDVAHACMFLAS 714
C+ PGII+TPL ++ ++N +G L EI K K K+ PL LG P ++A+ +FLAS
Sbjct: 179 CVCPGIIDTPLNEKSFLEN--NEGTL---EEIKKEKAKVNPLLRLGKPEEIANVMLFLAS 233
Query: 715 DMAKHITGSDIPVSGG 762
D++ ++TGS I GG
Sbjct: 234 DLSSYMTGSAITADGG 249
>sp|P39640|BACC_BACSU Bacilysin biosynthesis oxidoreductase bacC
Length = 253
Score = 132 bits (333), Expect = 9e-31
Identities = 90/256 (35%), Positives = 136/256 (53%), Gaps = 2/256 (0%)
Frame = +1
Query: 1 MNFDNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELSGRNVIFLFCN 180
MN +K +LI GG SGIG A V+ F A VV D+ G +V + + + F+ +
Sbjct: 1 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTD 60
Query: 181 VTIEDDIKSVINHIENIHGGKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHFLF 360
+T E + + + GG LD LINN G I +N+ FL
Sbjct: 61 ITDEAACQHAVESAVHTFGG-LDVLINNAGIEIV-APIHEMELSDWNKVLQVNLTGMFLM 118
Query: 361 CKYSMP-MLRKYRGCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVRVN 537
K+++ ML +G IIN S G + + Y +KG + +TKS+A+D A++ +RVN
Sbjct: 119 SKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVN 178
Query: 538 CISPGIINTPLLVQNTIDNCRLKGGLSYESEIDKMK-KLIPLGDLGDPIDVAHACMFLAS 714
C+ PGII+TPL ++ ++N +G L EI K K K+ PL LG P ++A+ +FLAS
Sbjct: 179 CVCPGIIDTPLNEKSFLEN--NEGTL---EEIKKEKAKVNPLLRLGKPEEIANVMLFLAS 233
Query: 715 DMAKHITGSDIPVSGG 762
D++ ++TGS I GG
Sbjct: 234 DLSSYMTGSAITADGG 249
>sp|Q9WYG0|Y325_THEMA Hypothetical oxidoreductase TM0325
Length = 251
Score = 130 bits (326), Expect = 6e-30
Identities = 87/258 (33%), Positives = 129/258 (50%), Gaps = 3/258 (1%)
Frame = +1
Query: 1 MNFDNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELS--GRNVIFLF 174
MNF K++LI G SGIG FA A V ++ G E V + G F+F
Sbjct: 1 MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIF 60
Query: 175 CNVTIEDDIKSVINHIENIHGGKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHF 354
+V +D + V +E G+LD L+NN G P I +NVK F
Sbjct: 61 GDVA-KDAEQIVKKTVETF--GRLDILVNNAGIVPYGN-IEETSEEDFDKTMAVNVKGPF 116
Query: 355 LFCKYSMPMLRKYRG-CIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVR 531
L KY++ ++K G I+N+SS+ G IG Y+++K A+ +T+SLA+D +YG+R
Sbjct: 117 LLSKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIR 176
Query: 532 VNCISPGIINTPLLVQNTIDNCRLKGGLSYESEIDKMKKLIPLGDLGDPIDVAHACMFLA 711
VN + PG + L+ R+K + E + KM IP+ LG ++A A +F A
Sbjct: 177 VNAVCPGTTQSEGLM------ARVKASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAA 230
Query: 712 SDMAKHITGSDIPVSGGA 765
D A +TGS I + GG+
Sbjct: 231 CDEAGFMTGSIINIDGGS 248
>sp|P46331|YXBG_BACSU Hypothetical oxidoreductase yxbG
Length = 273
Score = 126 bits (317), Expect = 6e-29
Identities = 82/253 (32%), Positives = 128/253 (50%), Gaps = 2/253 (0%)
Frame = +1
Query: 10 DNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNEL--SGRNVIFLFCNV 183
+NK +I G +GIG A + FA+ A V+ ++ E V+ + +G +V
Sbjct: 5 ENKTAVITGAATGIGQATAEVFANEGARVIIGDINKDQMEETVDAIRKNGGQAESFHLDV 64
Query: 184 TIEDDIKSVINHIENIHGGKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHFLFC 363
+ E+ +K+ + I++ G +D L NN G E K+ ++++ FL
Sbjct: 65 SDENSVKAFADQIKDACG-TIDILFNNAGVDQEGGKVHEYPVDLFDRIIAVDLRGTFLCS 123
Query: 364 KYSMPMLRKYRGCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVRVNCI 543
KY +P++ + G IIN SS G + Y KG IT +TK++A+D A G+RVN I
Sbjct: 124 KYLIPLMLENGGSIINTSSMSGRAADLDRSGYNAAKGGITNLTKAMAIDYARNGIRVNSI 183
Query: 544 SPGIINTPLLVQNTIDNCRLKGGLSYESEIDKMKKLIPLGDLGDPIDVAHACMFLASDMA 723
SPG I TPL+ + + G E + K + PLG LG P ++A +FLASD +
Sbjct: 184 SPGTIETPLIDKLAGTKEQEMG----EQFREANKWITPLGRLGQPKEMATVALFLASDDS 239
Query: 724 KHITGSDIPVSGG 762
++TG DI GG
Sbjct: 240 SYVTGEDITADGG 252
>sp|P50198|LINX_PSEPA 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (2,5-DDOL
dehydrogenase)
Length = 250
Score = 126 bits (316), Expect = 8e-29
Identities = 92/260 (35%), Positives = 132/260 (50%), Gaps = 7/260 (2%)
Frame = +1
Query: 16 KIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNEL--SGRNVIFLFCNVTI 189
K+ LI GG SG+GAA K+FA A VV +++ +V E+ +G + +F+ +VT
Sbjct: 8 KVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFIRLDVTD 67
Query: 190 EDDIKSVINHIENIHGGKLDCLINNVGT-HP---EDRKIXXXXXXXXXXXXNINVKSHFL 357
+ I + GG L L N G HP E+ I +N + FL
Sbjct: 68 AASWNNAIAAAVDGFGG-LTTLSNTAGIIHPGGFEEESIEGWNKMVA-----VNQTAIFL 121
Query: 358 FCKYSMPMLRKY-RGCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVRV 534
K ++P L K G IIN+SS +G +Y TK A+ M+K+ AL+ + GVRV
Sbjct: 122 GIKAAIPELVKSGNGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAALEFVDRGVRV 181
Query: 535 NCISPGIINTPLLVQNTIDNCRLKGGLSYESEIDKMKKLIPLGDLGDPIDVAHACMFLAS 714
N I PG +NTP+ D + + IP+G LGDPID+A+ +FLAS
Sbjct: 182 NTIVPGGMNTPITANVPPD------------VLKQQTSQIPMGKLGDPIDIANGALFLAS 229
Query: 715 DMAKHITGSDIPVSGGAEIG 774
D AK+ITG D+P+ GG +G
Sbjct: 230 DEAKYITGVDLPIDGGWSVG 249
>sp|Q9X248|FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
protein reductase)
Length = 246
Score = 124 bits (311), Expect = 3e-28
Identities = 86/260 (33%), Positives = 127/260 (48%), Gaps = 3/260 (1%)
Frame = +1
Query: 1 MNFDNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELSGR--NVIFLF 174
M + K+ LI G SGIG A FA ATV+ ++N + LV E G V
Sbjct: 1 MRLEGKVCLITGAASGIGKATTLLFAQEGATVIAGDISKENLDSLVKEAEGLPGKVDPYV 60
Query: 175 CNVTIEDDIKSVINHIENIHGGKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHF 354
NVT D IK V+ + +G ++D L+NN G D + N+N+K F
Sbjct: 61 LNVTDRDQIKEVVEKVVQKYG-RIDVLVNNAGI-TRDALLVRMKEEDWDAVINVNLKGVF 118
Query: 355 LFCKYSMP-MLRKYRGCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVR 531
+ +P M+++ G I+N+SS VG G YA +K + MTK+ A + A +R
Sbjct: 119 NVTQMVVPYMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGRNIR 178
Query: 532 VNCISPGIINTPLLVQNTIDNCRLKGGLSYESEIDKMKKLIPLGDLGDPIDVAHACMFLA 711
VN ++PG I TP + + + R E+ + + IPLG G P +VA +FLA
Sbjct: 179 VNAVAPGFIETP-MTEKLPEKAR-------ETALSR----IPLGRFGKPEEVAQVILFLA 226
Query: 712 SDMAKHITGSDIPVSGGAEI 771
SD + ++TG I + GG I
Sbjct: 227 SDESSYVTGQVIGIDGGLVI 246
>sp|P50160|TS2_MAIZE Sex determination protein tasselseed 2
Length = 336
Score = 121 bits (304), Expect = 2e-27
Identities = 85/274 (31%), Positives = 133/274 (48%), Gaps = 23/274 (8%)
Frame = +1
Query: 10 DNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELSGRNVIFLFCNVTI 189
D K+ ++ GG GIG A V+ FA A VV D G L + L G V F+ C+V++
Sbjct: 54 DGKVAIVTGGARGIGEAIVRLFAKHGARVVIADIDDAAGEALASAL-GPQVSFVRCDVSV 112
Query: 190 EDDIKSVINHIENIHGGKLDCLINNVGTHPED----RKIXXXXXXXXXXXXNINVKSHFL 357
EDD++ ++ + HGG+LD NN G R I +N L
Sbjct: 113 EDDVRRAVDWALSRHGGRLDVYCNNAGVLGRQTRAARSILSFDAAEFDRVLRVNALGAAL 172
Query: 358 FCKYSMPMLRKYR-GCIINMSSQVGTIGQKNAVTYAITKGAITAMTKSLALDEAEYGVRV 534
K++ + R G I++++S +G Y +K AI +TK+ A + +GVRV
Sbjct: 173 GMKHAARAMAPRRAGSIVSVASVAAVLGGLGPHAYTASKHAIVGLTKNAACELRAHGVRV 232
Query: 535 NCISPGIINTPLLV--------QNTIDNCR-----LKGGLSYESEIDKMKKLIP-----L 660
NC+SP + TP+L+ T D R L + + E++KM++++
Sbjct: 233 NCVSPFGVATPMLINAWRQGHDDATADADRDLDLDLDVTVPSDQEVEKMEEVVRGLATLK 292
Query: 661 GDLGDPIDVAHACMFLASDMAKHITGSDIPVSGG 762
G P D+A A +FLASD A++I+G ++ V GG
Sbjct: 293 GPTLRPRDIAEAVLFLASDEARYISGHNLVVDGG 326
>sp|Q8KWS9|BACC_BACAM Bacilysin biosynthesis oxidoreductase bacC
Length = 254
Score = 117 bits (294), Expect = 3e-26
Identities = 87/259 (33%), Positives = 135/259 (52%), Gaps = 5/259 (1%)
Frame = +1
Query: 1 MNFDNKIILIVGGTSGIGAACVKQFASTNATVVFCSNDQKNGNELVNELSGRNVIFLFCN 180
MN +K +LI GG SGIG A V+ F + A VV D+ G ++ + + + F+ +
Sbjct: 1 MNLTDKTVLITGGASGIGYAAVQAFLNQQANVVVADIDEAQGEAMIRKENNDRLHFVQTD 60
Query: 181 VTIEDDIKSVINHIENIHGGKLDCLINNVGTHPEDRKIXXXXXXXXXXXXNINVKSHFLF 360
+T E ++ I + GG LD LINN G I N+N+ FL
Sbjct: 61 ITNEPACQNAILSAVDKFGG-LDVLINNAGIEIV-APIHEMELSDWNKVLNVNLTGMFLM 118
Query: 361 CKYSMP-MLRKYRGCIINMSSQVGTIGQKNAVTYAITKGAI---TAMTKSLALDEAEYGV 528
K+++ ML+ +G IIN S G + + Y +KG + A + + A++ +
Sbjct: 119 SKHALKYMLKSGKGNIINTCSVGGVVAWPDIPAYNASKGGVLQTDAFYRPSII--AKHNI 176
Query: 529 RVNCISPGIINTPLLVQNTIDNCRLKGGLSYESEIDKMK-KLIPLGDLGDPIDVAHACMF 705
RVNC+ PGII+TPL ++ ++N +G L EI K K K+ PL LG P ++A+ +F
Sbjct: 177 RVNCVCPGIIDTPLNEKSFLEN--NEGTL---EEIKKEKAKVNPLLRLGKPEEIANVMLF 231
Query: 706 LASDMAKHITGSDIPVSGG 762
LASD++ ++TGS I GG
Sbjct: 232 LASDLSSYMTGSAITADGG 250
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,727,841
Number of Sequences: 369166
Number of extensions: 1548692
Number of successful extensions: 4905
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4448
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4577
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)