Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_L08
(496 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BXI6|TBC10_HUMAN TBC1 domain family member 10A (EBP50-... 95 8e-20
sp|P58802|TBC10_MOUSE TBC1 domain family member 10A (EBP50-... 95 8e-20
sp|Q60949|TBCD1_MOUSE TBC1 domain family member 1 57 2e-08
sp|O97790|TBCD1_BOVIN TBC1 domain family member 1 (Lyncein) 55 7e-08
sp|O60343|TBCD4_HUMAN TBC1 domain family member 4 (Akt subs... 55 9e-08
sp|Q86TI0|TBCD1_HUMAN TBC1 domain family member 1 55 9e-08
sp|Q8BYJ6|TBCD4_MOUSE TBC1 domain family member 4 (Akt subs... 55 1e-07
sp|Q09830|YAD4_SCHPO Hypothetical protein C4G8.04 in chromo... 48 1e-05
sp|P53258|GYP2_YEAST GTPase-activating protein GYP2 (MAC1-d... 43 4e-04
sp|O95759|TBCD8_HUMAN TBC1 domain family member 8 (Vascular... 43 5e-04
>sp|Q9BXI6|TBC10_HUMAN TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa)
(EPI64 protein)
Length = 508
Score = 95.1 bits (235), Expect = 8e-20
Identities = 43/117 (36%), Positives = 72/117 (61%)
Frame = +3
Query: 9 EVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKRA 188
+++P+ +M +WFMC F+R PW++V+RV DMFFCEG+K+IFR+ L L+K A G+ + +A
Sbjct: 264 KIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKVKA 323
Query: 189 HNSTESIVAFLRNLPPEVTTPEFIVSESLKFANIPAAEFVYEHLKQRRSYADGSSQL 359
+ LR+L P++ F+V E ++ + + EHL Q R + + +L
Sbjct: 324 CQGQYETIERLRSLSPKIMQEAFLVQEVVELP-VTERQIEREHLIQLRRWQETRGEL 379
>sp|P58802|TBC10_MOUSE TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa)
(EPI64 protein)
Length = 500
Score = 95.1 bits (235), Expect = 8e-20
Identities = 43/117 (36%), Positives = 71/117 (60%)
Frame = +3
Query: 9 EVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKRA 188
+++P+ +M +WFMC F R PW++V+RV DMFFCEG+K+IFR+ L L+K A G+ + +A
Sbjct: 264 KIDPLLYMTEWFMCAFARTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLKHALGSPEKLKA 323
Query: 189 HNSTESIVAFLRNLPPEVTTPEFIVSESLKFANIPAAEFVYEHLKQRRSYADGSSQL 359
+ LR+L P++ F+V E ++ + + EHL Q R + + +L
Sbjct: 324 CQGQYETIEQLRSLSPKIMQEAFLVQEVIELP-VTERQIEREHLIQLRRWQETRGEL 379
>sp|Q60949|TBCD1_MOUSE TBC1 domain family member 1
Length = 1255
Score = 57.4 bits (137), Expect = 2e-08
Identities = 28/79 (35%), Positives = 43/79 (54%)
Frame = +3
Query: 6 HEVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKR 185
HE+ P + WF+ +F FP V RV DM F +G +VIF++AL+L+
Sbjct: 1045 HEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLL---GSHKPLIL 1101
Query: 186 AHNSTESIVAFLRNLPPEV 242
H + E+IV F++N P +
Sbjct: 1102 QHENLETIVDFIKNTLPNL 1120
>sp|O97790|TBCD1_BOVIN TBC1 domain family member 1 (Lyncein)
Length = 556
Score = 55.5 bits (132), Expect = 7e-08
Identities = 27/79 (34%), Positives = 43/79 (54%)
Frame = +3
Query: 6 HEVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKR 185
HE+ P + WF+ +F FP V RV DM F +G +VIF++AL+L+
Sbjct: 346 HEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIFKVALSLL---GSHKPLIL 402
Query: 186 AHNSTESIVAFLRNLPPEV 242
H + E+IV F+++ P +
Sbjct: 403 QHENLETIVDFIKSTLPNL 421
>sp|O60343|TBCD4_HUMAN TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160)
Length = 1298
Score = 55.1 bits (131), Expect = 9e-08
Identities = 28/83 (33%), Positives = 46/83 (55%)
Frame = +3
Query: 6 HEVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKR 185
+E+ P + WF+ +F F V RV D+ F +G +VIF++AL+L+ + +
Sbjct: 1076 NEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLL---SSQETLIM 1132
Query: 186 AHNSTESIVAFLRNLPPEVTTPE 254
S E+IV FL+N P++ T E
Sbjct: 1133 ECESFENIVEFLKNTLPDMNTSE 1155
>sp|Q86TI0|TBCD1_HUMAN TBC1 domain family member 1
Length = 1168
Score = 55.1 bits (131), Expect = 9e-08
Identities = 27/79 (34%), Positives = 43/79 (54%)
Frame = +3
Query: 6 HEVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKR 185
HE+ P + WF+ +F FP V RV DM F +G +VIF++AL+L+
Sbjct: 958 HEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLL---GSHKPLIL 1014
Query: 186 AHNSTESIVAFLRNLPPEV 242
H + E+IV F+++ P +
Sbjct: 1015 QHENLETIVDFIKSTLPNL 1033
>sp|Q8BYJ6|TBCD4_MOUSE TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160)
Length = 1307
Score = 54.7 bits (130), Expect = 1e-07
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = +3
Query: 6 HEVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKR 185
+E+ P + WF+ +F FP V RV D+ F +G +VIF++AL+L+ + +
Sbjct: 1085 NEISPSLYAAPWFLTLFASQFPLGFVARVFDIIFLQGTEVIFKVALSLL---SSQEALIM 1141
Query: 186 AHNSTESIVAFLRNLPPEVTTPE 254
+ E+IV FL++ P++ T E
Sbjct: 1142 ECENFENIVEFLKSTLPDMNTTE 1164
>sp|Q09830|YAD4_SCHPO Hypothetical protein C4G8.04 in chromosome I
Length = 772
Score = 47.8 bits (112), Expect = 1e-05
Identities = 24/78 (30%), Positives = 41/78 (52%)
Frame = +3
Query: 39 WFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKRAHNSTESIVAF 218
WF+ ++T P R+ DM FC+G +FR+AL ++K+ A NS+ +I +F
Sbjct: 668 WFLSVYTDTLPTNISFRIFDMLFCDGYVCLFRVALTILKS---LKQQILACNSSSAIYSF 724
Query: 219 LRNLPPEVTTPEFIVSES 272
L +L P+ + E+
Sbjct: 725 LSDLVQYSFQPDSFIKEA 742
>sp|P53258|GYP2_YEAST GTPase-activating protein GYP2 (MAC1-dependent regulator) (MIC1
protein)
Length = 950
Score = 43.1 bits (100), Expect = 4e-04
Identities = 20/61 (32%), Positives = 36/61 (59%)
Frame = +3
Query: 6 HEVEPVYFMIDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAAGTDDAKR 185
H+++ + WF+ +F + P VR++D+FF G +F++ALA++K A DD +
Sbjct: 396 HDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINA--DDILQ 453
Query: 186 A 188
A
Sbjct: 454 A 454
>sp|O95759|TBCD8_HUMAN TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing
protein) (AD 3)
Length = 897
Score = 42.7 bits (99), Expect = 5e-04
Identities = 18/44 (40%), Positives = 29/44 (65%)
Frame = +3
Query: 33 IDWFMCIFTRNFPWATVVRVLDMFFCEGIKVIFRIALALVKAAA 164
+ WF+ +F P + V V+D FF +GIK IF++ LA+++A A
Sbjct: 422 LSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANA 465
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,493,917
Number of Sequences: 369166
Number of extensions: 1045267
Number of successful extensions: 3154
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3052
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3154
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3069744620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)