Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_L04
(820 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8TCT9|HM13_HUMAN Minor histocompatibility antigen H13 (... 241 2e-63
sp|Q9D8V0|HM13_MOUSE Minor histocompatibility antigen H13 (... 239 5e-63
sp|P49049|YJ95_CAEEL Hypothetical protein T05E11.5 in chrom... 94 3e-19
sp|P34248|YKK0_YEAST Hypothetical 67.5 kDa protein in APE1/... 55 2e-07
sp|Q8TCT6|PSL4_HUMAN Signal peptide peptidase-like 3 (SPP-l... 52 2e-06
sp|Q9CUS9|PSL4_MOUSE Signal peptide peptidase-like 3 (SPP-l... 50 6e-06
sp|Q9JJF9|PSL2_MOUSE Signal peptide peptidase-like 2A (SPP-... 43 0.001
sp|Q8TCT8|PSL2_HUMAN Signal peptide peptidase-like 2A (SPP-... 41 0.005
sp|Q8TCT7|PSL1_HUMAN Signal peptide peptidase-like 2B (SPP-... 38 0.029
sp|O35599|OPSG_MOUSE Green-sensitive opsin (Green cone phot... 31 3.6
>sp|Q8TCT9|HM13_HUMAN Minor histocompatibility antigen H13 (Signal peptide peptidase)
(Presenilin-like protein 3) (hIMP1 protein)
Length = 377
Score = 241 bits (614), Expect = 2e-63
Identities = 128/265 (48%), Positives = 165/265 (62%)
Frame = +2
Query: 26 PQGLVIAYFSLFLMAIVPIYIGAQKSVSRLRDQKKNGDNNVETLSNNDAAMFPLYASCAL 205
P+G+ +AY SL LMA++PI+ GA +SV R KN + ET+++ DAA FP+ ASC L
Sbjct: 29 PEGIALAYGSLLLMALLPIFFGALRSVRCARG--KNASDMPETITSRDAARFPIIASCTL 86
Query: 206 FGLYIFFKIFSKEYINMLLSTYFFFLGVLALSNTLNPLIEKYIPDLFQNCVYHLEIXXXX 385
GLY+FFKIFS+EYIN+LLS YFF LG+LALS+T++P + K+ P F N Y L
Sbjct: 87 LGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFT--- 143
Query: 386 XXXXXXXXXXXXXXXVTPXXXXXXXXXXXXXXEEPSETSAPQSSGDKSNKSSCECLFEYS 565
Q SG+ + + Y
Sbjct: 144 -----------------------------------------QGSGENKEE-----IINYE 157
Query: 566 YKRKEFLGLFIAALVGVWYMMTKHWIANNLFGLAFSISAVELMHLNKVITGCILLGGLFI 745
+ K+ + L ++++VGVWY++ KHWIANNLFGLAFS++ VEL+HLN V TGCILLGGLFI
Sbjct: 158 FDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFI 217
Query: 746 YDIFWVFGTNVMDTVAKSFEAPIKL 820
YD+FWVFGTNVM TVAKSFEAPIKL
Sbjct: 218 YDVFWVFGTNVMVTVAKSFEAPIKL 242
>sp|Q9D8V0|HM13_MOUSE Minor histocompatibility antigen H13 (Signal peptide peptidase)
(Presenilin-like protein 3)
Length = 378
Score = 239 bits (611), Expect = 5e-63
Identities = 130/273 (47%), Positives = 167/273 (61%)
Frame = +2
Query: 2 GTKPTIDDPQGLVIAYFSLFLMAIVPIYIGAQKSVSRLRDQKKNGDNNVETLSNNDAAMF 181
GT P+G+ +AY SL LMA++PI+ GA +SV R K+ + ET+++ DAA F
Sbjct: 21 GTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG--KSSSDMPETITSRDAARF 78
Query: 182 PLYASCALFGLYIFFKIFSKEYINMLLSTYFFFLGVLALSNTLNPLIEKYIPDLFQNCVY 361
P+ ASC L GLY+FFKIFS+EYIN+LLS YFF LG+LALS+T++P + K+ P F N Y
Sbjct: 79 PIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPANFPNRQY 138
Query: 362 HLEIXXXXXXXXXXXXXXXXXXXVTPXXXXXXXXXXXXXXEEPSETSAPQSSGDKSNKSS 541
L Q SG+ +
Sbjct: 139 QLLFT--------------------------------------------QGSGENKEE-- 152
Query: 542 CECLFEYSYKRKEFLGLFIAALVGVWYMMTKHWIANNLFGLAFSISAVELMHLNKVITGC 721
+ Y + K+ + L ++++VGVWY++ KHWIANNLFGLAFS++ VEL+HLN V TGC
Sbjct: 153 ---IINYEFDTKDLVCLGLSSVVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGC 209
Query: 722 ILLGGLFIYDIFWVFGTNVMDTVAKSFEAPIKL 820
ILLGGLFIYDIFWVFGTNVM TVAKSFEAPIKL
Sbjct: 210 ILLGGLFIYDIFWVFGTNVMVTVAKSFEAPIKL 242
>sp|P49049|YJ95_CAEEL Hypothetical protein T05E11.5 in chromosome IV
Length = 468
Score = 94.4 bits (233), Expect = 3e-19
Identities = 42/100 (42%), Positives = 65/100 (65%)
Frame = +2
Query: 521 DKSNKSSCECLFEYSYKRKEFLGLFIAALVGVWYMMTKHWIANNLFGLAFSISAVELMHL 700
+ + K E LF+ + R + + L + + + + +++ +HWI NN+ G++FSI +E +HL
Sbjct: 230 EDAKKKETEYLFKIDFDRYDIIALLMCSPILISHLLKRHWITNNIIGVSFSILGIERLHL 289
Query: 701 NKVITGCILLGGLFIYDIFWVFGTNVMDTVAKSFEAPIKL 820
G +LL GLF YDIFWVFGT+VM +VAK +API L
Sbjct: 290 ASFKAGSLLLVGLFFYDIFWVFGTDVMTSVAKGIDAPILL 329
Score = 39.3 bits (90), Expect = 0.013
Identities = 23/69 (33%), Positives = 43/69 (62%), Gaps = 3/69 (4%)
Frame = +2
Query: 53 SLFLMAIVPIYIGAQKSVSRLR---DQKKNGDNNVETLSNNDAAMFPLYASCALFGLYIF 223
+L+ M+I+ I IG+ +S +R D+K+ + ++ + +A FP+ AS LFGLY+F
Sbjct: 29 ALYGMSILCIIIGSIRSAQYIRTNIDKKRLIEGSI---TMREARKFPISASLVLFGLYLF 85
Query: 224 FKIFSKEYI 250
FK ++ ++
Sbjct: 86 FKPAAERFL 94
>sp|P34248|YKK0_YEAST Hypothetical 67.5 kDa protein in APE1/LAP4-CWP1 intergenic region
Length = 587
Score = 55.1 bits (131), Expect = 2e-07
Identities = 27/87 (31%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +2
Query: 566 YKRKEFLGLFIAALVGV--WYMMTKHWIANNLFGLAFSISAVELMHLNKVITGCILLGGL 739
Y + F+ ++V +Y+ W+ +N + +I ++ + L + +G ++L L
Sbjct: 303 YLNSALIVSFVLSIVSTVYFYLSPNDWLISNAVSMNMAIWSIAQLKLKNLKSGALILIAL 362
Query: 740 FIYDIFWVFGTNVMDTVAKSFEAPIKL 820
F YDI +VFGT+VM TVA + + P+KL
Sbjct: 363 FFYDICFVFGTDVMVTVATNLDIPVKL 389
>sp|Q8TCT6|PSL4_HUMAN Signal peptide peptidase-like 3 (SPP-like 3 protein) (Intramembrane
protease 2) (IMP2) (Presenilin-like protein 4)
Length = 385
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/94 (28%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Frame = +2
Query: 530 NKSSCECLFEYSYKRKEFLGLFIAALVGVWYMMTKHWIANNLFGLAFSISAVELMHLNKV 709
NK S C ++ E L ++ ++ + +++T HW+ + + ++ + + L +
Sbjct: 130 NKISFGCCGRFT--AAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSL 187
Query: 710 ITGCILLGGLFIYDIFWV------FGTNVMDTVA 793
C+LL GL IYD+FWV F +NVM VA
Sbjct: 188 KVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVA 221
>sp|Q9CUS9|PSL4_MOUSE Signal peptide peptidase-like 3 (SPP-like 3 protein) (Intramembrane
protease 2) (IMP2) (Presenilin-like protein 4)
Length = 384
Score = 50.4 bits (119), Expect = 6e-06
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 6/94 (6%)
Frame = +2
Query: 530 NKSSCECLFEYSYKRKEFLGLFIAALVGVWYMMTKHWIANNLFGLAFSISAVELMHLNKV 709
NK S C ++ E L ++ ++ + +++T HW+ + + ++ + L +
Sbjct: 129 NKISFGCCGRFT--AAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFDRLPSL 186
Query: 710 ITGCILLGGLFIYDIFWV------FGTNVMDTVA 793
C+LL GL IYD+FWV F +NVM VA
Sbjct: 187 KVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVA 220
>sp|Q9JJF9|PSL2_MOUSE Signal peptide peptidase-like 2A (SPP-like 2A protein) (SPPL2a
protein) (Intramembrane protease 3) (IMP3)
(Presenilin-like protein 2)
Length = 523
Score = 43.1 bits (100), Expect = 0.001
Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
Frame = +2
Query: 587 GLFIAALVGVWYMMTKH----WIANNLFGLAFSISAVELMHLNKVITGCILLGGLFIYDI 754
GL I+ V VW + WI ++ G+AF ++ ++ M L ++ ILLG L IYD+
Sbjct: 298 GLCISVAV-VWAVFRNEDRWAWILQDILGIAFCLNLIKTMKLPNFMSCVILLGLLLIYDV 356
Query: 755 FWVFGT 772
F+VF T
Sbjct: 357 FFVFIT 362
>sp|Q8TCT8|PSL2_HUMAN Signal peptide peptidase-like 2A (SPP-like 2A protein) (SPPL2a
protein) (Intramembrane protease 3) (IMP3)
(Presenilin-like protein 2)
Length = 520
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 4/66 (6%)
Frame = +2
Query: 587 GLFIAALVGVWYMMTKH----WIANNLFGLAFSISAVELMHLNKVITGCILLGGLFIYDI 754
GL IA V VW + WI ++ G+AF ++ ++ + L + ILLG L +YD+
Sbjct: 294 GLCIAVAV-VWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDV 352
Query: 755 FWVFGT 772
F+VF T
Sbjct: 353 FFVFIT 358
>sp|Q8TCT7|PSL1_HUMAN Signal peptide peptidase-like 2B (SPP-like 2B protein) (SPPL2b
protein) (Intramembrane protease 4) (IMP4)
(Presenilin-like protein 1)
Length = 564
Score = 38.1 bits (87), Expect = 0.029
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 8/79 (10%)
Frame = +2
Query: 560 YSYKRKE----FLGLFIAALVGVWYMMTKH----WIANNLFGLAFSISAVELMHLNKVIT 715
Y +KR + L LF A+ VW + W+ + G+AF + ++ + L
Sbjct: 260 YFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKA 319
Query: 716 GCILLGGLFIYDIFWVFGT 772
+LL LF+YDIF+VF T
Sbjct: 320 CTLLLLVLFLYDIFFVFIT 338
>sp|O35599|OPSG_MOUSE Green-sensitive opsin (Green cone photoreceptor pigment)
Length = 359
Score = 31.2 bits (69), Expect = 3.6
Identities = 25/105 (23%), Positives = 45/105 (42%), Gaps = 3/105 (2%)
Frame = +2
Query: 62 LMAIVPIYIGAQKSVSRLRDQKKNGDNNVETLSN-NDAAMFPLYASCALFGLYIFFKIFS 238
L IV Y+ ++ + Q+K ++ + + ++A C +G Y FF F+
Sbjct: 227 LSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVFAYCLCWGPYTFFACFA 286
Query: 239 KEYINMLLSTYFFFL-GVLALSNTL-NPLIEKYIPDLFQNCVYHL 367
+ L A S T+ NP+I ++ F+NC+ HL
Sbjct: 287 TAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFRNCILHL 331
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,817,053
Number of Sequences: 369166
Number of extensions: 1686714
Number of successful extensions: 4442
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4260
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4439
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)