Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_K10
(942 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Corta... 207 3e-53
sp|Q60598|SRC8_MOUSE Src substrate cortactin 204 2e-52
sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (On... 202 9e-52
sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific p... 182 1e-45
sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific p... 176 9e-44
sp|Q925Q9|SH3K1_RAT SH3-domain kinase binding protein 1 (SH... 67 7e-11
sp|Q8R550|SH3K1_MOUSE SH3-domain kinase binding protein 1 (... 66 1e-10
sp|Q14847|LASP1_HUMAN LIM and SH3 domain protein 1 (LASP-1)... 66 2e-10
sp|Q99MZ8|LASP1_RAT LIM and SH3 domain protein 1 (LASP-1) 65 2e-10
sp|Q61792|LASP1_MOUSE LIM and SH3 domain protein 1 (LASP-1)... 65 4e-10
>sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Cortactin)
Length = 563
Score = 207 bits (528), Expect = 3e-53
Identities = 126/326 (38%), Positives = 172/326 (52%), Gaps = 59/326 (18%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGK+GVQTDRQDKCA+GW+H+E++ H SQ+DY GFGGKFGVQ ERQD SAVG+++
Sbjct: 239 KGFGGKFGVQTDRQDKCALGWDHQEKVQLHESQKDYKSGFGGKFGVQTERQDPSAVGFDY 298
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE------------------------ 289
KE+ KH SQQDYSKGFGGKYGVQ DR DK+A +E
Sbjct: 299 KEKLAKHESQQDYSKGFGGKYGVQKDRMDKNAATFEDIEKPTSTYQKTKPVERVANKTSS 358
Query: 290 ---HKEEVGKHSSQTDQSKGFGGKFG-VQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTA 457
+ E + K Q D+ K + + ++Q++ E+ +K Q P PT
Sbjct: 359 IRANLENLAKEKEQEDRRKAEAERAQRMAREKQEQEEARRKLEEQAK-AKKQTPPPSPTT 417
Query: 458 ------TVTKKIEQLSVKEDIRIEEQSSNDPV----EPVAGYG------EEHHSHDIEET 589
T + + Q +V D ++S+ EP +GY +E S E
Sbjct: 418 QPAEPKTPSSPVYQDAVSYDAESAYKNSSTTYSAEHEPESGYKTTGSDYQEAVSQREAEY 477
Query: 590 EPQHNLETNQSSDE---------------GLIAVALFDFDGEEEDEVNFAAGDTITHIEK 724
EP+ E + D G+ A+AL+D+ +DE++F D IT+IE
Sbjct: 478 EPETVYEVAGAGDHYQAEENTYDEYENELGITAIALYDYQAAGDDEISFDPDDIITNIEM 537
Query: 725 IDSGWWVGVINGRKGMFPSNYVEINE 802
ID GWW GV GR G+FP+NYVE+ +
Sbjct: 538 IDDGWWRGVCKGRYGLFPANYVELRQ 563
Score = 197 bits (501), Expect = 4e-50
Identities = 94/148 (63%), Positives = 120/148 (81%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGK+GVQTDR D+ AVG+E++ + KHASQ+DYS GFGGK+GVQ +R DKSAVG+++
Sbjct: 128 KGFGGKFGVQTDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDY 187
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGV 361
+ +TEKH SQ+DYSKGFGGKYGV D+ DKSAVG+E++ + KH SQ D KGFGGKFGV
Sbjct: 188 QGKTEKHESQKDYSKGFGGKYGVDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGV 247
Query: 362 QSDRQDKSALGWDTEQVSKNVSHQNEPD 445
Q+DRQDK ALGWD ++ K H+++ D
Sbjct: 248 QTDRQDKCALGWDHQE--KVQLHESQKD 273
Score = 195 bits (496), Expect = 1e-49
Identities = 91/145 (62%), Positives = 120/145 (82%), Gaps = 1/145 (0%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
GFGGKYGVQ DR DK AVG++++ + KH SQ+DYS+GFGGK+GV K++ DKSAVG+E++
Sbjct: 166 GFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGVDKDKVDKSAVGFEYQ 225
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
+TEKH SQ+DY KGFGGK+GVQTDRQDK A+GW+H+E+V H SQ D GFGGKFGVQ
Sbjct: 226 GKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKVQLHESQKDYKSGFGGKFGVQ 285
Query: 365 SDRQDKSALGWD-TEQVSKNVSHQN 436
++RQD SA+G+D E+++K+ S Q+
Sbjct: 286 TERQDPSAVGFDYKEKLAKHESQQD 310
Score = 189 bits (481), Expect = 7e-48
Identities = 96/203 (47%), Positives = 130/203 (64%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGKYGV D+ DK AVG+E++ + KH SQ+DY +GFGGKFGVQ +RQDK A+GW+H
Sbjct: 202 KGFGGKYGVDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDH 261
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGV 361
+E+ + H SQ+DY GFGGK+GVQT+RQD SAVG+++KE++ KH SQ D SKGFGGK+GV
Sbjct: 262 QEKVQLHESQKDYKSGFGGKFGVQTERQDPSAVGFDYKEKLAKHESQQDYSKGFGGKYGV 321
Query: 362 QSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSVKEDIRIEEQSSNDPVEP 541
Q DR DK+A + E + K S + P V K + + +E+ D +
Sbjct: 322 QKDRMDKNAATF--EDIEKPTSTYQKTK-PVERVANKTSSIRANLENLAKEKEQEDRRKA 378
Query: 542 VAGYGEEHHSHDIEETEPQHNLE 610
A + E+ E + LE
Sbjct: 379 EAERAQRMAREKQEQEEARRKLE 401
Score = 181 bits (458), Expect = 3e-45
Identities = 86/147 (58%), Positives = 112/147 (76%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
G+GGK+GV+ DR DK AVG E++ +L KH SQ D +GFGGKFGVQ +R D+SAVG+E++
Sbjct: 92 GYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVKGFGGKFGVQTDRVDQSAVGFEYQ 151
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
+TEKH SQ+DYS GFGGKYGVQ DR DKSAVG++++ + KH SQ D SKGFGGK+GV
Sbjct: 152 GKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGVD 211
Query: 365 SDRQDKSALGWDTEQVSKNVSHQNEPD 445
D+ DKSA+G+ E K H+++ D
Sbjct: 212 KDKVDKSAVGF--EYQGKTEKHESQKD 236
Score = 134 bits (336), Expect = 5e-31
Identities = 64/112 (57%), Positives = 86/112 (76%)
Frame = +2
Query: 110 SQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE 289
S G+GGKFGV+++R DKSAVG E++ + KH SQ D KGFGGK+GVQTDR D+SAVG+E
Sbjct: 90 SHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVKGFGGKFGVQTDRVDQSAVGFE 149
Query: 290 HKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 445
++ + KH+SQ D S GFGGK+GVQ+DR DKSA+G+D + K H+++ D
Sbjct: 150 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQ--GKTEKHESQKD 199
>sp|Q60598|SRC8_MOUSE Src substrate cortactin
Length = 546
Score = 204 bits (520), Expect = 2e-52
Identities = 116/317 (36%), Positives = 164/317 (51%), Gaps = 50/317 (15%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGK+GVQTDRQDKCA+GW+H+E+L H SQ+DY GFGGKFGVQ ERQD SAVG+++
Sbjct: 230 KGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSSAVGFDY 289
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFG- 358
KE KH QQDY+KGFGGKYGVQ DR DK+A +E +V +T + K
Sbjct: 290 KERLAKHEPQQDYAKGFGGKYGVQKDRMDKNASTFEEVVQVPSAYQKTVPIEAVTSKTSN 349
Query: 359 -------VQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATV-----TKKIEQLSVKEDI 502
+ +R+ + + E+ + + E + + KK +
Sbjct: 350 IRANFENLAKEREQEDRRKAEAERAQRMAKERQEQEEARRKLEEQARAKKQTPPASPSPQ 409
Query: 503 RIEEQSSNDPVEPVAGYGEEHHSHDIEETEPQHNLET----------------------- 613
IE++ + P+ A + S+ E EP++++E
Sbjct: 410 PIEDRPPSSPIYEDAAPFKAEPSYRGSEPEPEYSIEAAGIPEAGSQQGLTYTSEPVYETT 469
Query: 614 --------------NQSSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGV 751
SD G+ A+AL+D+ +DE++F D IT+IE ID GWW GV
Sbjct: 470 EAPGHYQAEDDTYDGYESDLGITAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGV 529
Query: 752 INGRKGMFPSNYVEINE 802
GR G+FP+NYVE+ +
Sbjct: 530 CKGRYGLFPANYVELRQ 546
Score = 194 bits (494), Expect = 2e-49
Identities = 92/151 (60%), Positives = 120/151 (79%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
+GFGGK+GVQ DR D+ AVG+E++ + KHASQ+DYS GFGGK+GVQ +R DKSAVG+++
Sbjct: 119 RGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDY 178
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGV 361
+ +TEKH SQ+DYSKGFGGKYG+ D+ DKSAVG+E++ + KH SQ D KGFGGKFGV
Sbjct: 179 QGKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGV 238
Query: 362 QSDRQDKSALGWDTEQVSKNVSHQNEPDVPT 454
Q+DRQDK ALGWD ++ K H+++ D T
Sbjct: 239 QTDRQDKCALGWDHQE--KLQLHESQKDYKT 267
Score = 193 bits (490), Expect = 7e-49
Identities = 89/145 (61%), Positives = 119/145 (82%), Gaps = 1/145 (0%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
GFGGKYGVQ DR DK AVG++++ + KH SQ+DYS+GFGGK+G+ K++ DKSAVG+E++
Sbjct: 157 GFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGIDKDKVDKSAVGFEYQ 216
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
+TEKH SQ+DY KGFGGK+GVQTDRQDK A+GW+H+E++ H SQ D GFGGKFGVQ
Sbjct: 217 GKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQ 276
Query: 365 SDRQDKSALGWD-TEQVSKNVSHQN 436
S+RQD SA+G+D E+++K+ Q+
Sbjct: 277 SERQDSSAVGFDYKERLAKHEPQQD 301
Score = 187 bits (474), Expect = 5e-47
Identities = 93/203 (45%), Positives = 128/203 (63%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGKYG+ D+ DK AVG+E++ + KH SQ+DY +GFGGKFGVQ +RQDK A+GW+H
Sbjct: 193 KGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDH 252
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGV 361
+E+ + H SQ+DY GFGGK+GVQ++RQD SAVG+++KE + KH Q D +KGFGGK+GV
Sbjct: 253 QEKLQLHESQKDYKTGFGGKFGVQSERQDSSAVGFDYKERLAKHEPQQDYAKGFGGKYGV 312
Query: 362 QSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSVKEDIRIEEQSSNDPVEP 541
Q DR DK+A T + V + VP VT K + + +E+ D +
Sbjct: 313 QKDRMDKNA---STFEEVVQVPSAYQKTVPIEAVTSKTSNIRANFENLAKEREQEDRRKA 369
Query: 542 VAGYGEEHHSHDIEETEPQHNLE 610
A + E+ E + LE
Sbjct: 370 EAERAQRMAKERQEQEEARRKLE 392
Score = 179 bits (454), Expect = 1e-44
Identities = 84/147 (57%), Positives = 112/147 (76%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
G+GGK+GV+ DR D+ AVG E++ +L KH SQ D +GFGGKFGVQ +R D+SAVG+E++
Sbjct: 83 GYGGKFGVEQDRMDRSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQ 142
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
+TEKH SQ+DYS GFGGKYGVQ DR DKSAVG++++ + KH SQ D SKGFGGK+G+
Sbjct: 143 GKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQKDYSKGFGGKYGID 202
Query: 365 SDRQDKSALGWDTEQVSKNVSHQNEPD 445
D+ DKSA+G+ E K H+++ D
Sbjct: 203 KDKVDKSAVGF--EYQGKTEKHESQKD 227
Score = 129 bits (324), Expect = 1e-29
Identities = 61/112 (54%), Positives = 85/112 (75%)
Frame = +2
Query: 110 SQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE 289
S G+GGKFGV+++R D+SAVG E++ + KH SQ D +GFGGK+GVQ DR D+SAVG+E
Sbjct: 81 SHGYGGKFGVEQDRMDRSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE 140
Query: 290 HKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 445
++ + KH+SQ D S GFGGK+GVQ+DR DKSA+G+D + K H+++ D
Sbjct: 141 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQ--GKTEKHESQKD 190
>sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Length = 550
Score = 202 bits (515), Expect = 9e-52
Identities = 126/322 (39%), Positives = 168/322 (52%), Gaps = 55/322 (17%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGK+GVQTDRQDKCA+GW+H+E+L H SQ+DY GFGGKFGVQ ERQD +AVG+++
Sbjct: 230 KGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDY 289
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE------------------------ 289
KE+ KH SQQDYSKGFGGKYGVQ DR DK+A +E
Sbjct: 290 KEKLAKHESQQDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKTVPVEAVTSKTSN 349
Query: 290 ---HKEEVGKHSSQTDQSKGFGGKFG-VQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTA 457
+ E + K Q D+ K + + +RQ++ E+ ++ Q P P
Sbjct: 350 IRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEARRKLEEQAR-AKTQTPPVSPAP 408
Query: 458 TVTKKI--------EQLSVKEDIRIEEQSSNDPVEPV-----AGYGEEHHSHDI------ 580
T++ + S K ++ S EPV A Y E +
Sbjct: 409 QPTEERLPSSPVYEDAASFKAELSYRGPVSGTEPEPVYSMEAADYREASSQQGLAYATEA 468
Query: 581 --EETE-PQHNLETNQSSDE-----GLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSG 736
E E P H + + DE G AVAL+D+ +DE++F D IT+IE ID G
Sbjct: 469 VYESAEAPGHYPAEDSTYDEYENDLGYTAVALYDYQAAGDDEISFDPDDIITNIEMIDDG 528
Query: 737 WWVGVINGRKGMFPSNYVEINE 802
WW GV GR G+FP+NYVE+ +
Sbjct: 529 WWRGVCKGRYGLFPANYVELRQ 550
Score = 194 bits (494), Expect = 2e-49
Identities = 92/151 (60%), Positives = 120/151 (79%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
+GFGGK+GVQ DR D+ AVG+E++ + KHASQ+DYS GFGGK+GVQ +R DKSAVG+++
Sbjct: 119 RGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDY 178
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGV 361
+ +TEKH SQ+DYSKGFGGKYG+ D+ DKSAVG+E++ + KH SQ D KGFGGKFGV
Sbjct: 179 QGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGV 238
Query: 362 QSDRQDKSALGWDTEQVSKNVSHQNEPDVPT 454
Q+DRQDK ALGWD ++ K H+++ D T
Sbjct: 239 QTDRQDKCALGWDHQE--KLQLHESQKDYKT 267
Score = 194 bits (492), Expect = 4e-49
Identities = 89/145 (61%), Positives = 120/145 (82%), Gaps = 1/145 (0%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
GFGGKYGVQ DR DK AVG++++ + KH SQ+DYS+GFGGK+G+ K++ DKSAVG+E++
Sbjct: 157 GFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQ 216
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
+TEKH SQ+DY KGFGGK+GVQTDRQDK A+GW+H+E++ H SQ D GFGGKFGVQ
Sbjct: 217 GKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFGGKFGVQ 276
Query: 365 SDRQDKSALGWD-TEQVSKNVSHQN 436
S+RQD +A+G+D E+++K+ S Q+
Sbjct: 277 SERQDSAAVGFDYKEKLAKHESQQD 301
Score = 191 bits (486), Expect = 2e-48
Identities = 95/203 (46%), Positives = 131/203 (64%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGKYG+ D+ DK AVG+E++ + KH SQ+DY +GFGGKFGVQ +RQDK A+GW+H
Sbjct: 193 KGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDH 252
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGV 361
+E+ + H SQ+DY GFGGK+GVQ++RQD +AVG+++KE++ KH SQ D SKGFGGK+GV
Sbjct: 253 QEKLQLHESQKDYKTGFGGKFGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGV 312
Query: 362 QSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSVKEDIRIEEQSSNDPVEP 541
Q DR DK+A T + VS + VP VT K + + +E+ D +
Sbjct: 313 QKDRMDKNA---STFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEKEQEDRRKA 369
Query: 542 VAGYGEEHHSHDIEETEPQHNLE 610
A + E+ E + LE
Sbjct: 370 EAERAQRMAKERQEQEEARRKLE 392
Score = 180 bits (457), Expect = 5e-45
Identities = 85/147 (57%), Positives = 112/147 (76%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
G+GGK+GV+ DR DK AVG E++ +L KH SQ D +GFGGKFGVQ +R D+SAVG+E++
Sbjct: 83 GYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQ 142
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
+TEKH SQ+DYS GFGGKYGVQ DR DKSAVG++++ + KH SQ D SKGFGGK+G+
Sbjct: 143 GKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYGID 202
Query: 365 SDRQDKSALGWDTEQVSKNVSHQNEPD 445
D+ DKSA+G+ E K H+++ D
Sbjct: 203 KDKVDKSAVGF--EYQGKTEKHESQKD 227
Score = 130 bits (326), Expect = 7e-30
Identities = 62/112 (55%), Positives = 85/112 (75%)
Frame = +2
Query: 110 SQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE 289
S G+GGKFGV+++R DKSAVG E++ + KH SQ D +GFGGK+GVQ DR D+SAVG+E
Sbjct: 81 SHGYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFE 140
Query: 290 HKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 445
++ + KH+SQ D S GFGGK+GVQ+DR DKSA+G+D + K H+++ D
Sbjct: 141 YQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQ--GKTEKHESQRD 190
>sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1) (p75)
Length = 486
Score = 182 bits (462), Expect = 1e-45
Identities = 122/370 (32%), Positives = 177/370 (47%), Gaps = 103/370 (27%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
KGFGGKYGV+ DR DK AVG+++K E+ KH SQ+DYS+GFGG++GV+K++ DK+A+G+++
Sbjct: 118 KGFGGKYGVERDRADKSAVGFDYKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDY 177
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKE-------EVGKHSSQTDQSKG 340
K ETEKH SQ+DY+KGFGG+YG+Q DR DKSAVG+ E + + + ++G
Sbjct: 178 KGETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEMEAPTTAYKKTTPIEAASSGARG 237
Query: 341 FGGKFGVQSD-----------------RQDKSALGWDTEQVSKNVSHQNEPDVPTATVTK 469
KF ++ +Q++ A+ + + + V EP VP A + K
Sbjct: 238 LKAKFESMAEEKRKREEEEKAQQVARRQQERKAVTKRSPEAPQPVIAMEEPAVP-APLPK 296
Query: 470 KI---------------------------------------------------EQLSVKE 496
KI E L V+E
Sbjct: 297 KISSEAWPPVGTPPSSESEPVRTSREHPVPLLPIRQTLPEDNEEPPALPPRTLEGLQVEE 356
Query: 497 DIRIEEQSSNDP---VEPVAGYG-----EEHHSHDIEETEPQHNLETNQSSDE------- 631
+ E + +P EP Y + H D E + + LE SS
Sbjct: 357 EPVYEAEPEPEPEPEPEPENDYEDVEEMDRHEQEDEPEGDYEEVLEPEDSSFSSALAGSS 416
Query: 632 -------------GLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGM 772
G+ AVAL+D+ GE DE++F D IT IE +D GWW G +G G+
Sbjct: 417 GCPAGAGAGAVALGISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHGHFGL 476
Query: 773 FPSNYVEINE 802
FP+NYV++ E
Sbjct: 477 FPANYVKLLE 486
Score = 176 bits (446), Expect = 9e-44
Identities = 83/178 (46%), Positives = 129/178 (72%), Gaps = 5/178 (2%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
G+GG++GV+ DR DK AVG E+ E+ KH+SQ D ++GFGGK+GV+++R DKSAVG+++K
Sbjct: 82 GYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKGFGGKYGVERDRADKSAVGFDYK 141
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
E EKH SQ+DYS+GFGG+YGV+ D+ DK+A+G+++K E KH SQ D +KGFGG++G+Q
Sbjct: 142 GEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYKGETEKHESQRDYAKGFGGQYGIQ 201
Query: 365 SDRQDKSALGWDTEQVSKNVSHQNEPDVPTAT-----VTKKIEQLSVKEDIRIEEQSS 523
DR DKSA+G++ E + +++ + A+ + K E ++ ++ R EE+ +
Sbjct: 202 KDRVDKSAVGFN-EMEAPTTAYKKTTPIEAASSGARGLKAKFESMAEEKRKREEEEKA 258
Score = 136 bits (343), Expect = 7e-32
Identities = 63/112 (56%), Positives = 87/112 (77%)
Frame = +2
Query: 110 SQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE 289
S G+GG+FGV+++R DKSAVG E+ E EKH SQ D +KGFGGKYGV+ DR DKSAVG++
Sbjct: 80 SHGYGGRFGVERDRMDKSAVGHEYVAEVEKHSSQTDAAKGFGGKYGVERDRADKSAVGFD 139
Query: 290 HKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 445
+K EV KH+SQ D S+GFGG++GV+ D+ DK+ALG+D + + H+++ D
Sbjct: 140 YKGEVEKHTSQKDYSRGFGGRYGVEKDKWDKAALGYDYK--GETEKHESQRD 189
>sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1)
Length = 486
Score = 176 bits (446), Expect = 9e-44
Identities = 83/178 (46%), Positives = 129/178 (72%), Gaps = 5/178 (2%)
Frame = +2
Query: 5 GFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHK 184
G+GG++GV+ DR DK AVG E+ ++ KH+SQ D ++GFGGK+GV+++R DKSAVG+++K
Sbjct: 82 GYGGQFGVERDRMDKSAVGHEYVADVEKHSSQTDAARGFGGKYGVERDRADKSAVGFDYK 141
Query: 185 EETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQ 364
E EKH SQ+DYS GFGG+YGV+ D++DK+A+G+++K E KH SQ D +KGFGG++G+Q
Sbjct: 142 GEVEKHASQKDYSHGFGGRYGVEKDKRDKAALGYDYKGETEKHESQRDYAKGFGGQYGIQ 201
Query: 365 SDRQDKSALGWDTEQVSKNVSHQNEPDVPTAT-----VTKKIEQLSVKEDIRIEEQSS 523
DR DKSA+G++ E + +++ + A+ + K E L+ ++ R EE+ +
Sbjct: 202 KDRVDKSAVGFN-EMEAPTTAYKKTTPIEAASSGARGLKAKFESLAEEKRKREEEEKA 258
Score = 147 bits (371), Expect = 4e-35
Identities = 71/170 (41%), Positives = 116/170 (68%), Gaps = 7/170 (4%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEH 181
+GFGGKYGV+ DR DK AVG+++K E+ KHASQ+DYS GFGG++GV+K+++DK+A+G+++
Sbjct: 118 RGFGGKYGVERDRADKSAVGFDYKGEVEKHASQKDYSHGFGGRYGVEKDKRDKAALGYDY 177
Query: 182 KEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWEHKE-------EVGKHSSQTDQSKG 340
K ETEKH SQ+DY+KGFGG+YG+Q DR DKSAVG+ E + + + ++G
Sbjct: 178 KGETEKHESQRDYAKGFGGQYGIQKDRVDKSAVGFNEMEAPTTAYKKTTPIEAASSGARG 237
Query: 341 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSV 490
KF ++ + K + E+ ++ ++ Q + ++++++Q S+
Sbjct: 238 LKAKFESLAEEKRKR----EEEEKAQQMARQQQERKAVVKMSREVQQPSM 283
Score = 134 bits (336), Expect = 5e-31
Identities = 61/112 (54%), Positives = 87/112 (77%)
Frame = +2
Query: 110 SQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQDKSAVGWE 289
S G+GG+FGV+++R DKSAVG E+ + EKH SQ D ++GFGGKYGV+ DR DKSAVG++
Sbjct: 80 SHGYGGQFGVERDRMDKSAVGHEYVADVEKHSSQTDAARGFGGKYGVERDRADKSAVGFD 139
Query: 290 HKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 445
+K EV KH+SQ D S GFGG++GV+ D++DK+ALG+D + + H+++ D
Sbjct: 140 YKGEVEKHASQKDYSHGFGGRYGVEKDKRDKAALGYDYK--GETEKHESQRD 189
Score = 79.0 bits (193), Expect = 2e-14
Identities = 80/306 (26%), Positives = 125/306 (40%), Gaps = 41/306 (13%)
Frame = +2
Query: 2 KGFGGKYGVQTDRQDKCAVGWEHKE-------ELGKHASQQDYSQGFGGKFGVQKERQDK 160
KGFGG+YG+Q DR DK AVG+ E + + ++G KF E + K
Sbjct: 192 KGFGGQYGIQKDRVDKSAVGFNEMEAPTTAYKKTTPIEAASSGARGLKAKFESLAEEKRK 251
Query: 161 SAVGWEHKEETEKHGSQQDYSKGFGGKYGVQTDRQ--------DKSAVGWEHKEEVGKHS 316
E +E+ ++ QQ K V+ R+ ++ A + +++
Sbjct: 252 R----EEEEKAQQMARQQQERKAV-----VKMSREVQQPSMPVEEPAAPAQLPKKISSEV 302
Query: 317 SQTDQSKGFGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSVKE 496
+S V+S R++ T Q S +H + + P A + E L V E
Sbjct: 303 WPPAESHLPPESQPVRS-RREYPVPSLPTRQ-SPLQNHLEDNEEPPALPPRTPEGLQVVE 360
Query: 497 DIRIEEQSSNDPVEPVAGYGEEHHSH---------------------DIEETEPQHNLET 613
+ E +P EP Y E + D+ E E +L
Sbjct: 361 EPVYEAAPELEP-EPEPDYEPEPETEPDYEDVGELDRQDEDAEGDYEDVLEPEDTPSLSY 419
Query: 614 NQ-----SSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFP 778
+ G+ A+AL+D+ GE DE++F D IT IE +D GWW G G G+FP
Sbjct: 420 QAGPSAGAGGAGISAIALYDYQGEGSDELSFDPDDIITDIEMVDEGWWRGQCRGHFGLFP 479
Query: 779 SNYVEI 796
+NYV++
Sbjct: 480 ANYVKL 485
>sp|Q925Q9|SH3K1_RAT SH3-domain kinase binding protein 1 (SH3 containing, expressed in
tumorigenic astrocytes) (Regulator of ubiquitous kinase)
(Ruk)
Length = 709
Score = 67.0 bits (162), Expect = 7e-11
Identities = 31/67 (46%), Positives = 45/67 (67%), Gaps = 1/67 (1%)
Frame = +2
Query: 641 AVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYV-EINE*KNIY 817
A+ FD+ + +DE+ + G+ IT+I K D GWW G INGR+G+FP N+V EI K++
Sbjct: 4 AIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIK--KDVK 61
Query: 818 KHLLINR 838
K LL N+
Sbjct: 62 KDLLSNK 68
Score = 55.8 bits (133), Expect = 2e-07
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +2
Query: 650 LFDFDGEEEDEVNFAAGDTITHIEK--IDSGWWVGVINGRKGMFPSNYVEI 796
+F ++ + +DE+ GD +T I K ID GWW G +NGR+G+FP N+V++
Sbjct: 319 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKL 369
Score = 55.5 bits (132), Expect = 2e-07
Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 488 VKEDIRIEEQSSNDPVEPVAGYGEEHHSHDIEE----TEPQHNLETNQSSDEGLIAVAL- 652
+K+D++ + S+ P +P+ HD+ + L TN+ + +
Sbjct: 56 IKKDVKKDLLSNKAPEKPM---------HDVSSGNSLLSSETILRTNKRGERRRRRCQVA 106
Query: 653 FDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYVE 793
F + + +DE+ GD I + +++ GWW GV+NG+ GMFPSN+++
Sbjct: 107 FSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153
>sp|Q8R550|SH3K1_MOUSE SH3-domain kinase binding protein 1 (SH3 containing, expressed in
tumorigenic astrocytes) (Regulator of ubiquitous kinase)
(Ruk)
Length = 709
Score = 66.2 bits (160), Expect = 1e-10
Identities = 31/67 (46%), Positives = 45/67 (67%), Gaps = 1/67 (1%)
Frame = +2
Query: 641 AVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYV-EINE*KNIY 817
A+ FD+ + +DE+ + G+ IT+I K D GWW G INGR+G+FP N+V EI K++
Sbjct: 4 AIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIK--KDMK 61
Query: 818 KHLLINR 838
K LL N+
Sbjct: 62 KDLLSNK 68
Score = 55.8 bits (133), Expect = 2e-07
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +2
Query: 650 LFDFDGEEEDEVNFAAGDTITHIEK--IDSGWWVGVINGRKGMFPSNYVEI 796
+F ++ + +DE+ GD +T I K ID GWW G +NGR+G+FP N+V++
Sbjct: 319 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKL 369
Score = 54.7 bits (130), Expect = 4e-07
Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 5/107 (4%)
Frame = +2
Query: 488 VKEDIRIEEQSSNDPVEPVAGYGEEHHSHDIEE----TEPQHNLETNQSSDEGLIAVAL- 652
+K+D++ + S+ P +P+ HD+ + L TN+ + +
Sbjct: 56 IKKDMKKDLLSNKAPEKPM---------HDVSSGNALLSSETILRTNKRGERRRRRCQVA 106
Query: 653 FDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYVE 793
F + + +DE+ GD I + +++ GWW GV+NG+ GMFPSN+++
Sbjct: 107 FSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153
>sp|Q14847|LASP1_HUMAN LIM and SH3 domain protein 1 (LASP-1) (MLN 50)
Length = 261
Score = 65.9 bits (159), Expect = 2e-10
Identities = 58/248 (23%), Positives = 96/248 (38%), Gaps = 3/248 (1%)
Frame = +2
Query: 59 GWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGG 238
G+E K H +Q ++ ++ ++Q + +KEE EK+ KG G
Sbjct: 46 GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN-------KGKGF 98
Query: 239 KYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDRQDKSALGWDTEQVSK 418
T + + + H G G G++ +R+D D +
Sbjct: 99 SVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERRDSQ----DGSSYRR 154
Query: 419 NVSHQNEPDVPTATVTKKIEQLSVKEDIRIEEQSSNDPV-EPVAGYGEEHHSHDIEETEP 595
+ Q +PT+ + +Q PV + GY E I+ + P
Sbjct: 155 PLEQQQPHHIPTSAP--------------VYQQPQQQPVAQSYGGYKEPAAPVSIQRSAP 200
Query: 596 QHNLETNQSSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVI--NGRKG 769
G A++D+ +EDEV+F GDTI ++++ID GW G + G G
Sbjct: 201 ---------GGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTG 251
Query: 770 MFPSNYVE 793
M P+NYVE
Sbjct: 252 MLPANYVE 259
>sp|Q99MZ8|LASP1_RAT LIM and SH3 domain protein 1 (LASP-1)
Length = 263
Score = 65.5 bits (158), Expect = 2e-10
Identities = 62/251 (24%), Positives = 97/251 (38%), Gaps = 6/251 (2%)
Frame = +2
Query: 59 GWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGG 238
G+E K H +Q ++ ++ ++Q + +KEE EK+ KG G
Sbjct: 46 GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN-------KGKGF 98
Query: 239 KYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDR---QDKSALGWDTEQ 409
T + + + H G G G++ +R QD S+ TEQ
Sbjct: 99 SVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGIEPERREAQDSSSYRRPTEQ 158
Query: 410 VSKNVSHQNEPDVPTATVTKKIEQLSVKEDIRIEEQSSNDPVEP-VAGYGEEHHSHDIEE 586
H +PT+ + +Q V P GY E I+
Sbjct: 159 QQPQPHH-----IPTSAP--------------VYQQPQQQQVTPSYGGYKEPAAPVSIQR 199
Query: 587 TEPQHNLETNQSSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVI--NG 760
+ P G A++D+ +EDEV+F GDTI ++++ID GW G + G
Sbjct: 200 SAP---------GGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTG 250
Query: 761 RKGMFPSNYVE 793
GM P+NYVE
Sbjct: 251 DTGMLPANYVE 261
>sp|Q61792|LASP1_MOUSE LIM and SH3 domain protein 1 (LASP-1) (MLN 50)
Length = 263
Score = 64.7 bits (156), Expect = 4e-10
Identities = 59/250 (23%), Positives = 98/250 (39%), Gaps = 5/250 (2%)
Frame = +2
Query: 59 GWEHKEELGKHASQQDYSQGFGGKFGVQKERQDKSAVGWEHKEETEKHGSQQDYSKGFGG 238
G+E K H +Q ++ ++ ++Q + +KEE EK+ KG G
Sbjct: 46 GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN-------KGKGF 98
Query: 239 KYGVQTDRQDKSAVGWEHKEEVGKHSSQTDQSKGFGGKFGVQSDR---QDKSALGWDTEQ 409
T + + + H G G GV+ +R QD S+ TEQ
Sbjct: 99 SVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGVEPERREAQDSSSYRRPTEQ 158
Query: 410 VSKNVSHQNEPDVPTATVTKKIEQLSVKEDIRIEEQSSNDPVEPVAGYGEEHHSHDIEET 589
H +PT+ + Q ++ + +P PV+
Sbjct: 159 QQPQPHH-----IPTSA---PVYQQPQQQQMTSSYGGYKEPAAPVS-------------- 196
Query: 590 EPQHNLETNQSSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVI--NGR 763
++ + G A++D+ +EDEV+F GDTI ++++ID GW G + G
Sbjct: 197 -----IQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGD 251
Query: 764 KGMFPSNYVE 793
GM P+NYVE
Sbjct: 252 TGMLPANYVE 261
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 110,150,022
Number of Sequences: 369166
Number of extensions: 2385980
Number of successful extensions: 8746
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7632
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8589
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9750928390
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)