Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_K05
(462 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O00418|EF2K_HUMAN Elongation factor 2 kinase (eEF-2 kina... 72 6e-13
sp|O08796|EF2K_MOUSE Elongation factor 2 kinase (eEF-2 kina... 72 8e-13
sp|P70531|EF2K_RAT Elongation factor 2 kinase (eEF-2 kinase... 72 8e-13
sp|O01991|EF2K_CAEEL Elongation factor 2 kinase (eEF-2 kina... 57 2e-08
sp|O00763|COA2_HUMAN Acetyl-CoA carboxylase 2 (ACC-beta) [I... 33 0.40
sp|Q9UBV2|SEL1L_HUMAN Sel-1 homolog precursor (Suppressor o... 31 1.5
sp|P10911|MCF2_HUMAN Proto-oncogene DBL (Proto-oncogene MCF... 31 1.5
sp|Q9Z2G6|SEL1L_MOUSE Sel-1 homolog precursor (Suppressor o... 31 1.5
sp|Q80Z70|SEL1L_RAT Sel-1 homolog precursor (Suppressor of ... 31 1.5
sp|Q9ESM7|SEL1L_MESAU Sel-1 homolog precursor (Suppressor o... 31 1.5
>sp|O00418|EF2K_HUMAN Elongation factor 2 kinase (eEF-2 kinase) (eEF-2K)
(Calcium/calmodulin-dependent eukaryotic elongation
factor 2 kinase)
Length = 725
Score = 72.0 bits (175), Expect = 6e-13
Identities = 41/98 (41%), Positives = 59/98 (60%)
Frame = +3
Query: 3 EAVKWYKRAFEAANKPDGQLDSKDAEGRYDSADDLMPPQEILAAMAELHFKGGYGLERNC 182
EA+ WY A E + +G G YD D P +LA AE+ F GGYGLE++
Sbjct: 636 EALHWYNTALEMTDCDEG--------GEYDGMQD-EPRYMMLAREAEMLFTGGYGLEKDP 686
Query: 183 QLAGELYSQAAEIATNALQGRQAVKYYELSDIAYSQDE 296
Q +G+LY+QAAE A A++GR A +YY+ ++ A++Q E
Sbjct: 687 QRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
>sp|O08796|EF2K_MOUSE Elongation factor 2 kinase (eEF-2 kinase) (eEF-2K)
(Calcium/calmodulin-dependent eukaryotic elongation
factor 2 kinase)
Length = 724
Score = 71.6 bits (174), Expect = 8e-13
Identities = 40/98 (40%), Positives = 58/98 (59%)
Frame = +3
Query: 3 EAVKWYKRAFEAANKPDGQLDSKDAEGRYDSADDLMPPQEILAAMAELHFKGGYGLERNC 182
EA+ WY A E + +G G YD D P +LA AE+ GG+GL++N
Sbjct: 635 EALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNP 685
Query: 183 QLAGELYSQAAEIATNALQGRQAVKYYELSDIAYSQDE 296
Q +G+LY+QAAE A A++GR A +YYE ++ A++Q E
Sbjct: 686 QRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
>sp|P70531|EF2K_RAT Elongation factor 2 kinase (eEF-2 kinase) (eEF-2K)
(Calcium/calmodulin-dependent eukaryotic elongation
factor 2 kinase)
Length = 724
Score = 71.6 bits (174), Expect = 8e-13
Identities = 40/98 (40%), Positives = 58/98 (59%)
Frame = +3
Query: 3 EAVKWYKRAFEAANKPDGQLDSKDAEGRYDSADDLMPPQEILAAMAELHFKGGYGLERNC 182
EA+ WY A E + +G G YD D P +LA AE+ GG+GL++N
Sbjct: 635 EALHWYNTALETTDCDEG--------GEYDGIQD-EPQYALLAREAEMLLTGGFGLDKNP 685
Query: 183 QLAGELYSQAAEIATNALQGRQAVKYYELSDIAYSQDE 296
Q +G+LY+QAAE A A++GR A +YYE ++ A++Q E
Sbjct: 686 QRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
>sp|O01991|EF2K_CAEEL Elongation factor 2 kinase (eEF-2 kinase) (eEF-2K)
(Calcium/calmodulin-dependent eukaryotic elongation
factor 2 kinase)
Length = 768
Score = 57.4 bits (137), Expect = 2e-08
Identities = 33/92 (35%), Positives = 56/92 (60%)
Frame = +3
Query: 3 EAVKWYKRAFEAANKPDGQLDSKDAEGRYDSADDLMPPQEILAAMAELHFKGGYGLERNC 182
+++ WY+R + + +LDS + + S L EILA MAE++ +GGYGL ++
Sbjct: 677 KSIDWYQRV--VGFQEEEELDSDCGKTTFSSFAPLTR-HEILAKMAEMYKEGGYGLNQDF 733
Query: 183 QLAGELYSQAAEIATNALQGRQAVKYYELSDI 278
+ A L+++AAE A A+ G+ A KYYE +++
Sbjct: 734 ERAYGLFNEAAEAAMEAMNGKLANKYYEKAEM 765
>sp|O00763|COA2_HUMAN Acetyl-CoA carboxylase 2 (ACC-beta) [Includes: Biotin carboxylase ]
Length = 2483
Score = 32.7 bits (73), Expect = 0.40
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Frame = +3
Query: 18 YKRAFEAANKPD-GQLDSKDAEGRYDSADDLMPP--QEILAAMAELHFKGGYGLER 176
YK+ E +PD D KD EGR + +DL+ P ++ A+ H G LE+
Sbjct: 2280 YKKLMEQLGEPDLSDKDRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEK 2335
>sp|Q9UBV2|SEL1L_HUMAN Sel-1 homolog precursor (Suppressor of lin-12-like protein)
(Sel-1L)
Length = 794
Score = 30.8 bits (68), Expect = 1.5
Identities = 17/54 (31%), Positives = 26/54 (48%)
Frame = +3
Query: 135 MAELHFKGGYGLERNCQLAGELYSQAAEIATNALQGRQAVKYYELSDIAYSQDE 296
+ +LH GG G+E+N Q A + ++ AA + Y E SDI +E
Sbjct: 379 LGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNE 432
>sp|P10911|MCF2_HUMAN Proto-oncogene DBL (Proto-oncogene MCF-2) [Contains: MCF2
transforming protein; DBL transforming protein]
Length = 925
Score = 30.8 bits (68), Expect = 1.5
Identities = 15/52 (28%), Positives = 27/52 (51%)
Frame = +1
Query: 175 EIASWLANYTVKLQKLPQMLFKDAKLLNIMNFLILHIHKMNVLNSFLLPFIC 330
++ +A K++KL + +LL+ F+ILH HK+ + + L IC
Sbjct: 246 DVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLIC 297
>sp|Q9Z2G6|SEL1L_MOUSE Sel-1 homolog precursor (Suppressor of lin-12-like protein)
(Sel-1L)
Length = 790
Score = 30.8 bits (68), Expect = 1.5
Identities = 17/54 (31%), Positives = 26/54 (48%)
Frame = +3
Query: 135 MAELHFKGGYGLERNCQLAGELYSQAAEIATNALQGRQAVKYYELSDIAYSQDE 296
+ +LH GG G+E+N Q A + ++ AA + Y E SDI +E
Sbjct: 375 LGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNE 428
>sp|Q80Z70|SEL1L_RAT Sel-1 homolog precursor (Suppressor of lin-12-like protein)
(Sel-1L)
Length = 794
Score = 30.8 bits (68), Expect = 1.5
Identities = 17/54 (31%), Positives = 26/54 (48%)
Frame = +3
Query: 135 MAELHFKGGYGLERNCQLAGELYSQAAEIATNALQGRQAVKYYELSDIAYSQDE 296
+ +LH GG G+E+N Q A + ++ AA + Y E SDI +E
Sbjct: 379 LGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNE 432
>sp|Q9ESM7|SEL1L_MESAU Sel-1 homolog precursor (Suppressor of lin-12-like protein)
(Sel-1L)
Length = 794
Score = 30.8 bits (68), Expect = 1.5
Identities = 17/54 (31%), Positives = 26/54 (48%)
Frame = +3
Query: 135 MAELHFKGGYGLERNCQLAGELYSQAAEIATNALQGRQAVKYYELSDIAYSQDE 296
+ +LH GG G+E+N Q A + ++ AA + Y E SDI +E
Sbjct: 379 LGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNE 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,026,804
Number of Sequences: 369166
Number of extensions: 831141
Number of successful extensions: 2232
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2201
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2232
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2584230740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)