Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_J19
(519 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P22892|AP1G1_MOUSE Adapter-related protein complex 1 gam... 76 4e-14
sp|O43747|AP1G1_HUMAN Adapter-related protein complex 1 gam... 76 4e-14
sp|O88512|AP1G2_MOUSE Adapter-related protein complex 1 gam... 67 2e-11
sp|O75843|AP1G2_HUMAN Adapter-related protein complex 1 gam... 60 4e-09
sp|Q8BMI3|GGA3_MOUSE ADP-ribosylation factor binding protei... 50 4e-06
sp|Q9NZ52|GGA3_HUMAN ADP-ribosylation factor binding protei... 49 5e-06
sp|Q9UJY5|GGA1_HUMAN ADP-ribosylation factor binding protei... 46 6e-05
sp|Q8R0H9|GGA1_MOUSE ADP-ribosylation factor binding protei... 45 1e-04
sp|Q9UJY4|GGA2_HUMAN ADP-ribosylation factor binding protei... 44 2e-04
sp|Q6P5E6|GGA2_MOUSE ADP-ribosylation factor binding protei... 44 3e-04
>sp|P22892|AP1G1_MOUSE Adapter-related protein complex 1 gamma 1 subunit (Gamma-adaptin)
(Adaptor protein complex AP-1 gamma-1 subunit) (Golgi
adaptor HA1/AP1 adaptin gamma-1 subunit) (Clathrin
assembly protein complex 1 gamma-1 large chain)
Length = 822
Score = 76.3 bits (186), Expect = 4e-14
Identities = 41/106 (38%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Frame = +2
Query: 11 ELTFSFERISNSQST--VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG- 181
++ F+FER + + S +T+ A N+ + F+FQAAVPK+FQL LL+PSS + F
Sbjct: 716 KIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFNT 775
Query: 182 GSLTQLLKLSNPNKQPWKMKIRLQYRLNGEVKSVQHQLDTFPSDLW 319
G++TQ++K+ NP KQ +M+I+L Y G +++ FP W
Sbjct: 776 GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSW 821
>sp|O43747|AP1G1_HUMAN Adapter-related protein complex 1 gamma 1 subunit (Gamma-adaptin)
(Adaptor protein complex AP-1 gamma-1 subunit) (Golgi
adaptor HA1/AP1 adaptin gamma-1 subunit) (Clathrin
assembly protein complex 1 gamma-1 large chain)
Length = 822
Score = 76.3 bits (186), Expect = 4e-14
Identities = 41/106 (38%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Frame = +2
Query: 11 ELTFSFERISNSQST--VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG- 181
++ F+FER + + S +T+ A N+ + F+FQAAVPK+FQL LL+PSS + F
Sbjct: 716 KIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNT 775
Query: 182 GSLTQLLKLSNPNKQPWKMKIRLQYRLNGEVKSVQHQLDTFPSDLW 319
G++TQ++K+ NP KQ +M+I+L Y G +++ FP W
Sbjct: 776 GTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSW 821
>sp|O88512|AP1G2_MOUSE Adapter-related protein complex 1 gamma 2 subunit (Gamma2-adaptin)
(Adaptor protein complex AP-1 gamma-2 subunit) (G2ad)
Length = 791
Score = 67.4 bits (163), Expect = 2e-11
Identities = 34/89 (38%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Frame = +2
Query: 56 VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFGG-SLTQLLKLSNPNKQPW 232
VT N+ + + F+ QAAVPKSFQL L APS + + GG +TQ+ ++ NPN+ P
Sbjct: 702 VTATTTNSSKEDVTHFVCQAAVPKSFQLQLQAPSGNTIPAQGGLPITQVFRILNPNQAPL 761
Query: 233 KMKIRLQYRLNGEVKSVQHQLDTFPSDLW 319
++K+RL Y +G+ ++D P + W
Sbjct: 762 RLKLRLTYNHSGQPVQEIFEVDNLPVETW 790
>sp|O75843|AP1G2_HUMAN Adapter-related protein complex 1 gamma 2 subunit (Gamma2-adaptin)
(Adaptor protein complex AP-1 gamma-2 subunit) (G2ad)
Length = 785
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Frame = +2
Query: 11 ELTFSFERISNSQST--VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFGG 184
+L SF R + + +T+ A N + F+ QAAVPKS QL L APS + + GG
Sbjct: 679 QLNLSFIRPPENPALLLITITATNFSEGDVTHFICQAAVPKSLQLQLQAPSGNTVPARGG 738
Query: 185 -SLTQLLKLSNPNKQPWKMKIRLQYRLNGEVKSVQHQLDTFPSDLW 319
+TQL ++ NPNK P ++K+RL Y + +++ P + W
Sbjct: 739 LPITQLFRILNPNKAPLRLKLRLTYDHFHQSVQEIFEVNNLPVESW 784
>sp|Q8BMI3|GGA3_MOUSE ADP-ribosylation factor binding protein GGA3 (Golgi-localized,
gamma ear-containing, ARF-binding protein 3)
Length = 718
Score = 49.7 bits (117), Expect = 4e-06
Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
Frame = +2
Query: 56 VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG-----GSLTQLLKLSNPN 220
V + +N + + QAAVPKS ++ L PS L PF ++TQ++ L+NP
Sbjct: 622 VVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPM 681
Query: 221 KQPWKMKIRLQYRLNGEVKSVQHQLDTFP 307
K+ +++ +L + L ++ + ++D FP
Sbjct: 682 KEKVRLRYKLTFALGEQLSTELGEVDQFP 710
>sp|Q9NZ52|GGA3_HUMAN ADP-ribosylation factor binding protein GGA3 (Golgi-localized,
gamma ear-containing, ARF-binding protein 3)
Length = 723
Score = 49.3 bits (116), Expect = 5e-06
Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
Frame = +2
Query: 56 VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG-----GSLTQLLKLSNPN 220
V + +N + + QAAVPKS ++ L PS L PF ++TQ++ L+NP
Sbjct: 627 VVVSMLNTAPLPVKSIVLQAAVPKSMKVKLQPPSGTELSPFSPIQPPAAITQVMLLANPL 686
Query: 221 KQPWKMKIRLQYRLNGEVKSVQHQLDTFP 307
K+ +++ +L + L ++ + ++D FP
Sbjct: 687 KEKVRLRYKLTFALGEQLSTEVGEVDQFP 715
>sp|Q9UJY5|GGA1_HUMAN ADP-ribosylation factor binding protein GGA1 (Golgi-localized,
gamma ear-containing, ARF-binding protein 1)
(Gamma-adaptin related protein 1)
Length = 639
Score = 45.8 bits (107), Expect = 6e-05
Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
Frame = +2
Query: 56 VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG-----GSLTQLLKLSNPN 220
V + ++ Q I +FQ+AVPK ++ L PS L F ++TQ+L L+NP
Sbjct: 543 VVVSMLSTAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHPSAITQVLLLANPQ 602
Query: 221 KQPWKMKIRLQYRLNGEVKSVQHQLDTFP 307
K+ +++ +L + + + + +D FP
Sbjct: 603 KEKVRLRYKLTFTMGDQTYNEMGDVDQFP 631
>sp|Q8R0H9|GGA1_MOUSE ADP-ribosylation factor binding protein GGA1 (Golgi-localized,
gamma ear-containing, ARF-binding protein 1)
(Gamma-adaptin-related protein 1)
Length = 635
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
Frame = +2
Query: 56 VTLHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG-----GSLTQLLKLSNPN 220
V + ++ Q I +FQ+AVPK ++ L PS L F ++TQ+L L+NP
Sbjct: 539 VVVSMLSTAPQPIRNIVFQSAVPKVMKVRLQPPSGTELPAFNPIVHPSAITQVLLLANPQ 598
Query: 221 KQPWKMKIRLQYRLNGEVKSVQHQLDTFP 307
K+ +++ +L + + + + +D FP
Sbjct: 599 KEKVRLRYKLIFTMGDQTYNEMGDVDQFP 627
>sp|Q9UJY4|GGA2_HUMAN ADP-ribosylation factor binding protein GGA2 (Golgi-localized,
gamma ear-containing, ARF-binding protein 2)
(Gamma-adaptin related protein 2) (VHS domain and ear
domain of gamma-adaptin) (Vear)
Length = 613
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Frame = +2
Query: 62 LHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG-----GSLTQLLKLSNPNKQ 226
L ++ Q + +FQ AVPKS ++ L SS L F ++Q+L L NP+K+
Sbjct: 519 LTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKE 578
Query: 227 PWKMKIRLQYRLNGEVKSVQHQLDTFP 307
P +++ +L + G+ S ++ FP
Sbjct: 579 PIRLRYKLTFNQGGQPFSEVGEVKDFP 605
>sp|Q6P5E6|GGA2_MOUSE ADP-ribosylation factor binding protein GGA2 (Golgi-localized,
gamma ear-containing, ARF-binding protein 2)
(Gamma-adaptin-related protein 2)
Length = 603
Score = 43.5 bits (101), Expect = 3e-04
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 5/87 (5%)
Frame = +2
Query: 62 LHAINNGNQLIDQFLFQAAVPKSFQLVLLAPSSDNLMPFG-----GSLTQLLKLSNPNKQ 226
L ++ Q + +FQ AVPKS ++ L SS L F ++Q L L NP+K+
Sbjct: 509 LTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQTLLLDNPHKE 568
Query: 227 PWKMKIRLQYRLNGEVKSVQHQLDTFP 307
P +++ +L + G+ S ++ FP
Sbjct: 569 PIRLRYKLTFNQGGQPFSEVGEVKDFP 595
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,115,798
Number of Sequences: 369166
Number of extensions: 1120196
Number of successful extensions: 2149
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2107
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2138
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3403581975
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)