Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_H22
(424 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 (hRAD50) 42 5e-04
sp|Q9UZC8|RAD50_PYRAB DNA double-strand break repair rad50 ... 41 0.001
sp|Q9ZM46|IF2_HELPJ Translation initiation factor IF-2 40 0.002
sp|Q6PCJ1|DYNA_XENLA Dynactin-1 40 0.002
sp|Q9EQ09|OLR1_MOUSE Oxidized low-density lipoprotein recep... 40 0.003
sp|Q97I38|YI16_CLOAB Hypothetical UPF0144 protein CAC1816 40 0.003
sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle 39 0.006
sp|P53278|YG3A_YEAST Hypothetical 92.7 kDa protein in ASN2-... 38 0.010
sp|O33600|RAD50_SULAC DNA double-strand break repair rad50 ... 38 0.010
sp|P70336|ROCK2_MOUSE Rho-associated protein kinase 2 (Rho-... 38 0.010
>sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 (hRAD50)
Length = 1312
Score = 42.0 bits (97), Expect = 5e-04
Identities = 27/81 (33%), Positives = 47/81 (58%), Gaps = 4/81 (4%)
Frame = +1
Query: 172 KTQISDLEAITHSNKELIKNLKNNVDKQKTSLRKLSENLSSAVNNVEAEKSYNS-VKQMH 348
+ QI+ EA S+KE++K+ +N +D K L+++ NLS + K+ +S KQM
Sbjct: 224 RDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQME 283
Query: 349 K---EMKEKYENLNKRLNEEL 402
K E++EK E + + +E+L
Sbjct: 284 KDNSELEEKMEKVFQGTDEQL 304
Score = 31.2 bits (69), Expect = 0.93
Identities = 19/81 (23%), Positives = 41/81 (50%)
Frame = +1
Query: 178 QISDLEAITHSNKELIKNLKNNVDKQKTSLRKLSENLSSAVNNVEAEKSYNSVKQMHKEM 357
Q+S+ E E ++ ++ ++D QK R L +NL+ N E +K++ +E
Sbjct: 986 QLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRNEE-------LKEVEEER 1038
Query: 358 KEKYENLNKRLNEELQAEQQK 420
K+ + + + ++++E QK
Sbjct: 1039 KQHLKEMGQMQVLQMKSEHQK 1059
>sp|Q9UZC8|RAD50_PYRAB DNA double-strand break repair rad50 ATPase
Length = 880
Score = 41.2 bits (95), Expect = 0.001
Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 10/100 (10%)
Frame = +1
Query: 127 LRQKNMAILEMIEQRKTQISDLEAITHSNKEL------IKNLKNNVDKQKTSLRKLSENL 288
L +K + I IE++K +IS+LE I +L + LK D+ ++ LR+L + L
Sbjct: 261 LEEKIVQIERSIEEKKAKISELEEIVKDIPKLQEKEKEYRKLKGFRDEYESKLRRLEKEL 320
Query: 289 SSAVNNVEAE----KSYNSVKQMHKEMKEKYENLNKRLNE 396
S + ++A K K+ +E++EK + KRL E
Sbjct: 321 SKWESELKAIEEVIKEGEKKKERAEEIREKLSEIEKRLEE 360
Score = 36.6 bits (83), Expect = 0.022
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 6/104 (5%)
Frame = +1
Query: 130 RQKNMAILEMIEQRKTQISDLEAI------THSNKELIKNLKNNVDKQKTSLRKLSENLS 291
RQ E +E+ +I +LE ++ ++ LKN ++K+KT L + E L+
Sbjct: 578 RQLRELGFESVEELNLRIQELEEFHDKYVEAKKSESELRELKNKLEKEKTELDQAFEMLA 637
Query: 292 SAVNNVEAEKSYNSVKQMHKEMKEKYENLNKRLNEELQAEQQKR 423
N +E E + K ++L + NEE E+++R
Sbjct: 638 DVENEIE-------------EKEAKLKDLESKFNEEEYEEKRER 668
>sp|Q9ZM46|IF2_HELPJ Translation initiation factor IF-2
Length = 949
Score = 40.4 bits (93), Expect = 0.002
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 8/95 (8%)
Frame = +1
Query: 127 LRQKNMAILEMIEQRKTQISDL-EAITHSNKELIKNLKNNVDKQKTSLRKLSE------- 282
+++K + I+ E + + + +A++HS E K + K + +L KL++
Sbjct: 121 IKKKEIEIVNTFENQTPLVENTPKAVSHSQIEKAKQKLQEIQKSREALNKLTQSNTNTTN 180
Query: 283 NLSSAVNNVEAEKSYNSVKQMHKEMKEKYENLNKR 387
N +SA N A+K + VK+ +E+K ++EN+ +R
Sbjct: 181 NANSASNVSNAKKEISEVKKQEQEIK-RHENIKRR 214
>sp|Q6PCJ1|DYNA_XENLA Dynactin-1
Length = 1232
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/102 (22%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Frame = +1
Query: 127 LRQKNMAILEMIEQRKTQISDLEAITHSNKELIKNLKNNVDKQKTSLRKLSENLSSAVNN 306
L ++N+ + E + + + +SDLEAI N EL +N + + + L + A
Sbjct: 401 LAERNLDLEEKVRELRETVSDLEAINEMNDELQENARETELELREQLDMAGARVREAEKR 460
Query: 307 VEAEK----SYNSVKQMHKEMKEKYENLNKRLNEELQAEQQK 420
VEA + Y + ++++ + +N L + +A +K
Sbjct: 461 VEAAQETVADYQQTIKKYRDLTAHLQEVNSELRNQQEASVEK 502
>sp|Q9EQ09|OLR1_MOUSE Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1)
(Lectin-type oxidized LDL receptor 1) (Lectin-like
oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1)
(LOX-1) [Contains: Oxidized low-density lipoprotein
receptor 1, soluble form]
Length = 363
Score = 39.7 bits (91), Expect = 0.003
Identities = 24/108 (22%), Positives = 57/108 (52%), Gaps = 10/108 (9%)
Frame = +1
Query: 124 KLRQKNMAILEMIEQRKTQISDLEAITHSNKELIKNLKNNVD----------KQKTSLRK 273
KL +K+ E++++ + L+ +S++E + LK +D K++ L +
Sbjct: 111 KLNEKSKEQEELLQKNQNLQEALQRAANSSEESQRELKGKIDTITRKLDEKSKEQEELLQ 170
Query: 274 LSENLSSAVNNVEAEKSYNSVKQMHKEMKEKYENLNKRLNEELQAEQQ 417
+ +NL A+ +++ NS ++ +E+K K + L +LNE+ + +++
Sbjct: 171 MIQNLQEAL-----QRAANSSEESQRELKGKIDTLTLKLNEKSKEQEE 213
Score = 28.1 bits (61), Expect = 7.9
Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 12/67 (17%)
Frame = +1
Query: 253 QKTSLRKLSENLSSAVNNVEAE------------KSYNSVKQMHKEMKEKYENLNKRLNE 396
Q T LR++S+ L N+ + K+ N+ ++ KE+K K + L ++LNE
Sbjct: 55 QWTQLRQVSDLLKQYQANLTQQDRILEGQMLAQQKAENASQESKKELKGKIDTLTQKLNE 114
Query: 397 ELQAEQQ 417
+ + +++
Sbjct: 115 KSKEQEE 121
>sp|Q97I38|YI16_CLOAB Hypothetical UPF0144 protein CAC1816
Length = 514
Score = 39.7 bits (91), Expect = 0.003
Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 7/95 (7%)
Frame = +1
Query: 136 KNMAILEMIEQRKTQISDLEAITHSNKELIKNLKNN-------VDKQKTSLRKLSENLSS 294
K A LE E+ SDL+ T + I+ L+ +DK+ L K L+
Sbjct: 56 KKEATLEAKEEAHRLRSDLDKETRERRNEIQRLERRNLQREETLDKKNDLLEKRENGLNE 115
Query: 295 AVNNVEAEKSYNSVKQMHKEMKEKYENLNKRLNEE 399
N+++ + N+++Q++KE +EK E L+ +EE
Sbjct: 116 RENSIQERQ--NTIEQLYKEEREKLEQLSGLTSEE 148
>sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle
Length = 1938
Score = 38.5 bits (88), Expect = 0.006
Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Frame = +1
Query: 124 KLRQKNMAILEMIEQRKTQISDLEAITHSNKELIKNLKNNVDKQKTSLRKLSENLS---- 291
KL Q + + +E+ K D+E ++ +K+ + NV+ + R+L EN+
Sbjct: 1023 KLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEA 1082
Query: 292 --SAVNNVEAEKSYNSVKQMHKEMKEKYENLNKRLNEELQAEQQKR 423
S++N+ + E N V Q+ +++KE + + L EEL+AE+ R
Sbjct: 1083 EISSLNS-KLEDEQNLVSQLQRKIKELQARI-EELEEELEAERNAR 1126
Score = 34.3 bits (77), Expect = 0.11
Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Frame = +1
Query: 154 EMIEQRKTQISDLEAITHSNKELIKNLKNNVDKQKTSLRKLSENLSSAVNNV-----EAE 318
E + + +DLE I + NLK ++ + +L+K ++ + N + E
Sbjct: 921 ERLLDEEDAAADLEGIKKKMEADNANLKKDIGDLENTLQKAEQDKAHKDNQISTLQGEIS 980
Query: 319 KSYNSVKQMHKEMKEKYENLNKRLNEELQAEQQK 420
+ + +++KE K+ E NK+ ++ LQAE+ K
Sbjct: 981 QQDEHIGKLNKE-KKALEEANKKTSDSLQAEEDK 1013
>sp|P53278|YG3A_YEAST Hypothetical 92.7 kDa protein in ASN2-PHB1 intergenic region
Length = 816
Score = 37.7 bits (86), Expect = 0.010
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Frame = +1
Query: 124 KLRQKNMAILEMIEQRK--TQISDLEAITHSNKELIKNLKNNVDKQKTSLRKLSENLSSA 297
KL +KN+ +LE +E ++ QI+D++ S + +K +KT L +++ L
Sbjct: 605 KLHEKNVQVLESVENKEYLPQINDIDNQISSLLNEVTIIKQENANEKTQLSAITKRLED- 663
Query: 298 VNNVEAEKSYNSVKQMHKEMKEKYENLNKRLNEELQAE 411
E +K +E K K ENL ++ +EL+ +
Sbjct: 664 ----ERRAHEEQLKLEAEERKRKEENLLEKQRQELEEQ 697
>sp|O33600|RAD50_SULAC DNA double-strand break repair rad50 ATPase
Length = 886
Score = 37.7 bits (86), Expect = 0.010
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 4/70 (5%)
Frame = +1
Query: 223 IKNLKNNVDKQKTSLRKLSENLSSAVNNVEAEKSYNSVKQMHKEMKEK---YENLNKRLN 393
I +LK+ ++ + L++ E L E EK Y +++ KE++EK YE + KRL
Sbjct: 304 IDSLKSQINVVENDLKRKKEKLKRKKELEEKEKQYEEIEKRKKELEEKEKQYEEIEKRLT 363
Query: 394 EELQ-AEQQK 420
L+ E+QK
Sbjct: 364 YVLKNIERQK 373
>sp|P70336|ROCK2_MOUSE Rho-associated protein kinase 2 (Rho-associated, coiled-coil
containing protein kinase 2) (p164 ROCK-2)
Length = 1388
Score = 37.7 bits (86), Expect = 0.010
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 11/110 (10%)
Frame = +1
Query: 121 LKLRQKNMAILEMIEQRKTQISDLEAITHSNKEL------IKNLKNNVDKQKTSLRKLSE 282
LK+ Q+ M K Q + + S K++ + +K N++KQ T LRK +
Sbjct: 794 LKIEQETQKRCLMQNDLKMQTQQVNTLKMSEKQIKQENNHLMEMKMNLEKQNTELRKERQ 853
Query: 283 N----LSSAVNNVEAEKSYNSV-KQMHKEMKEKYENLNKRLNEELQAEQQ 417
+ + + +EAE+ ++++ K +E+KE+ E K L +ELQ ++Q
Sbjct: 854 DADGQMKELQDQLEAEQYFSTLYKTQVRELKEENEEKTK-LCKELQQKKQ 902
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.314 0.124 0.330
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,338,771
Number of Sequences: 369166
Number of extensions: 564840
Number of successful extensions: 3458
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3190
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3432
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2052714815
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)