Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_H18
(513 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase 1 (S6K) (... 73 5e-13
sp|P67998|KS6B1_RABIT Ribosomal protein S6 kinase I (S6K) (... 73 5e-13
sp|Q8BSK8|KS6B1_MOUSE Ribosomal protein S6 kinase I (S6K) (... 73 5e-13
sp|P67999|KS6B1_RAT Ribosomal protein S6 kinase I (S6K) (p7... 73 5e-13
sp|Q9Z1M4|KS6B2_MOUSE Ribosomal protein S6 kinase beta 2 (S... 71 2e-12
sp|Q16513|PKN2_HUMAN Protein kinase N2 (Protein kinase C-li... 71 2e-12
sp|P70268|PKN1_MOUSE Serine/threonine-protein kinase N1 (Pr... 70 3e-12
sp|Q63433|PKN1_RAT Protein kinase N1 (Protein kinase C-like... 70 4e-12
sp|Q16512|PKN1_HUMAN Protein kinase N1 (Protein kinase C-li... 69 7e-12
sp|Q8BWW9|PKN2_MOUSE Protein kinase N2 (Protein kinase C-li... 67 2e-11
>sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase 1 (S6K) (S6K1) (70 kDa ribosomal
protein S6 kinase 1) (p70 S6 kinase alpha)
(p70(S6K)-alpha) (p70-S6K) (p70-alpha)
Length = 525
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/95 (42%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Frame = +3
Query: 66 ARLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVI 245
+RLG D E++ H FFR INW++ AR+++PPF P L S +DVS FD + V
Sbjct: 334 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 393
Query: 246 SP--STADDSNCYWFENFSYVSPQVYLEFSEQGSF 344
SP ST +S F F+YV+P V E+ SF
Sbjct: 394 SPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSF 428
>sp|P67998|KS6B1_RABIT Ribosomal protein S6 kinase I (S6K) (p70-S6K)
Length = 525
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/95 (42%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Frame = +3
Query: 66 ARLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVI 245
+RLG D E++ H FFR INW++ AR+++PPF P L S +DVS FD + V
Sbjct: 334 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 393
Query: 246 SP--STADDSNCYWFENFSYVSPQVYLEFSEQGSF 344
SP ST +S F F+YV+P V E+ SF
Sbjct: 394 SPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSF 428
>sp|Q8BSK8|KS6B1_MOUSE Ribosomal protein S6 kinase I (S6K) (p70-S6K)
Length = 525
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/95 (42%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Frame = +3
Query: 66 ARLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVI 245
+RLG D E++ H FFR INW++ AR+++PPF P L S +DVS FD + V
Sbjct: 334 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 393
Query: 246 SP--STADDSNCYWFENFSYVSPQVYLEFSEQGSF 344
SP ST +S F F+YV+P V E+ SF
Sbjct: 394 SPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSF 428
>sp|P67999|KS6B1_RAT Ribosomal protein S6 kinase I (S6K) (p70-S6K)
Length = 525
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/95 (42%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Frame = +3
Query: 66 ARLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVI 245
+RLG D E++ H FFR INW++ AR+++PPF P L S +DVS FD + V
Sbjct: 334 SRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVD 393
Query: 246 SP--STADDSNCYWFENFSYVSPQVYLEFSEQGSF 344
SP ST +S F F+YV+P V E+ SF
Sbjct: 394 SPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSF 428
>sp|Q9Z1M4|KS6B2_MOUSE Ribosomal protein S6 kinase beta 2 (S6K-beta 2) (70 kDa ribosomal
protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase
beta) (p70 S6Kbeta) (S6K2)
Length = 485
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/94 (41%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = +3
Query: 69 RLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVIS 248
R+GG D +++RH FFR INWD AR + PPF P L S +DVS FD + V S
Sbjct: 311 RIGGGLGDAADVQRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFDARFTRQTPVDS 370
Query: 249 P--STADDSNCYWFENFSYVSPQVYLEFSEQGSF 344
P + +S F F+YV+P V E SF
Sbjct: 371 PDDTALSESANQAFLGFTYVAPSVLDSIKEGFSF 404
>sp|Q16513|PKN2_HUMAN Protein kinase N2 (Protein kinase C-like 2) (Protein-kinase C-related
kinase 2)
Length = 984
Score = 70.9 bits (172), Expect = 2e-12
Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 4/83 (4%)
Frame = +3
Query: 69 RLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVIS 248
RLG SEKD E++K+H FFR I+W +++KPPFIP + R+DVS FD SE +++
Sbjct: 899 RLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILT 958
Query: 249 ----PSTADDSNCYWFENFSYVS 305
P + F +F Y++
Sbjct: 959 PprePRILSEEEQEMFRDFDYIA 981
>sp|P70268|PKN1_MOUSE Serine/threonine-protein kinase N1 (Protein kinase C-like 1)
(Protein-kinase C-related kinase 1) (Protein kinase
C-like PKN) (Serine-threonine protein kinase N)
Length = 946
Score = 70.1 bits (170), Expect = 3e-12
Identities = 31/61 (50%), Positives = 40/61 (65%)
Frame = +3
Query: 69 RLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVIS 248
RLG +E+D E++K+ FFRS+ WD AR L PPF+P LS R DVS FD+ E +S
Sbjct: 861 RLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLS 920
Query: 249 P 251
P
Sbjct: 921 P 921
>sp|Q63433|PKN1_RAT Protein kinase N1 (Protein kinase C-like 1) (Protein-kinase C-related
kinase 1) (Protein kinase C-like PKN) (Serine-threonine
protein kinase N) (Protease-activated kinase 1) (PAK-1)
Length = 946
Score = 69.7 bits (169), Expect = 4e-12
Identities = 30/61 (49%), Positives = 41/61 (67%)
Frame = +3
Query: 69 RLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVIS 248
RLG +E+D E++K+ FFR+++WD AR L PPF+P LS R DVS FD+ E +S
Sbjct: 861 RLGSTERDAEDVKKQPFFRTLDWDALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLS 920
Query: 249 P 251
P
Sbjct: 921 P 921
>sp|Q16512|PKN1_HUMAN Protein kinase N1 (Protein kinase C-like 1) (Protein-kinase C-related
kinase 1) (Protein kinase C-like PKN) (Serine-threonine
protein kinase N) (Protein kinase PKN-alpha)
Length = 942
Score = 68.9 bits (167), Expect = 7e-12
Identities = 30/61 (49%), Positives = 40/61 (65%)
Frame = +3
Query: 69 RLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVIS 248
RLG SE+D E++K+ FFR++ W+ AR L PPF+P LS R DVS FD+ E +S
Sbjct: 857 RLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLS 916
Query: 249 P 251
P
Sbjct: 917 P 917
>sp|Q8BWW9|PKN2_MOUSE Protein kinase N2 (Protein kinase C-like 2) (Protein-kinase C-related
kinase 2)
Length = 983
Score = 67.0 bits (162), Expect = 2e-11
Identities = 31/83 (37%), Positives = 47/83 (56%), Gaps = 4/83 (4%)
Frame = +3
Query: 69 RLGGSEKDVEEIKRHFFFRSINWDKAFARELKPPFIPELSSRDDVSLFDKNIVSEPCVIS 248
RLG EKD E++K+H FFR +W +++KPPF+P + R+DVS FD SE +++
Sbjct: 898 RLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILT 957
Query: 249 PSTAD----DSNCYWFENFSYVS 305
P + F +F YV+
Sbjct: 958 PprePRILLEEEQEMFHDFDYVA 980
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,843,174
Number of Sequences: 369166
Number of extensions: 992231
Number of successful extensions: 3065
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2965
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3031
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3304927425
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)