Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_026_F10 (286 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q94547|RGA_DROME Regulator of gene activity (Regena prot... 71 9e-13 sp|Q9NZN8|CNOT2_HUMAN CCR4-NOT transcription complex subuni... 64 8e-11 sp|Q8C5L3|CNOT2_MOUSE CCR4-NOT transcription complex subuni... 64 8e-11 sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subuni... 45 5e-05 sp|Q8K0V4|CNOT3_MOUSE CCR4-NOT transcription complex subuni... 45 5e-05 sp|P06100|NOT2_YEAST General negative regulator of transcri... 44 9e-05 sp|Q12514|NOT5_YEAST General negative regulator of transcri... 37 0.018 sp|Q64PD6|FMT_BACFR Methionyl-tRNA formyltransferase >gi|73... 28 6.5 sp|Q58356|TRM1_METJA N(2),N(2)-dimethylguanosine tRNA methy... 28 6.5
>sp|Q94547|RGA_DROME Regulator of gene activity (Regena protein) Length = 585 Score = 70.9 bits (172), Expect = 9e-13 Identities = 31/73 (42%), Positives = 48/73 (65%) Frame = +2 Query: 20 RPHDMDYAVPKEYRIRHSILDKLADPLPEKLSDETLFWIFYNLTGEECQTTAAKQLMARQ 199 R D+++ VP EY I +I DKL P+ +KL ++ LF++FY G+ Q AA +L +R+ Sbjct: 458 RAQDVEFNVPPEYLINFAIRDKLTAPVLKKLQEDLLFFLFYTNIGDMMQLMAAAELHSRE 517 Query: 200 WRYNKRDKFWLTR 238 WRY+ +K W+TR Sbjct: 518 WRYHVEEKIWITR 530
>sp|Q9NZN8|CNOT2_HUMAN CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) Length = 540 Score = 64.3 bits (155), Expect = 8e-11 Identities = 34/86 (39%), Positives = 51/86 (59%) Frame = +2 Query: 20 RPHDMDYAVPKEYRIRHSILDKLADPLPEKLSDETLFWIFYNLTGEECQTTAAKQLMARQ 199 RP D+D+ VP EY I DKLA + ++ LF+++Y G+ Q AA +L R Sbjct: 409 RPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRD 468 Query: 200 WRYNKRDKFWLTRDSKGVNEPTVHPN 277 WRY+K ++ W+TR + G+ EPT+ N Sbjct: 469 WRYHKEERVWITR-APGM-EPTMKTN 492
>sp|Q8C5L3|CNOT2_MOUSE CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) Length = 540 Score = 64.3 bits (155), Expect = 8e-11 Identities = 34/86 (39%), Positives = 51/86 (59%) Frame = +2 Query: 20 RPHDMDYAVPKEYRIRHSILDKLADPLPEKLSDETLFWIFYNLTGEECQTTAAKQLMARQ 199 RP D+D+ VP EY I DKLA + ++ LF+++Y G+ Q AA +L R Sbjct: 409 RPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQLLAAVELFNRD 468 Query: 200 WRYNKRDKFWLTRDSKGVNEPTVHPN 277 WRY+K ++ W+TR + G+ EPT+ N Sbjct: 469 WRYHKEERVWITR-APGM-EPTMKTN 492
>sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) Length = 753 Score = 45.1 bits (105), Expect = 5e-05 Identities = 20/45 (44%), Positives = 28/45 (62%) Frame = +2 Query: 104 EKLSDETLFWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTR 238 ++LS ETLF+IFY L G + Q AAK L + WR++ + W R Sbjct: 664 QRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQR 708
>sp|Q8K0V4|CNOT3_MOUSE CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) Length = 751 Score = 45.1 bits (105), Expect = 5e-05 Identities = 20/45 (44%), Positives = 28/45 (62%) Frame = +2 Query: 104 EKLSDETLFWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTR 238 ++LS ETLF+IFY L G + Q AAK L + WR++ + W R Sbjct: 662 QRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQR 706
>sp|P06100|NOT2_YEAST General negative regulator of transcription subunit 2 Length = 191 Score = 44.3 bits (103), Expect = 9e-05 Identities = 20/42 (47%), Positives = 25/42 (59%) Frame = +2 Query: 116 DETLFWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWLTRD 241 DETLF++FY G Q +L R WRY+K K WLT+D Sbjct: 109 DETLFFLFYKHPGTVIQELTYLELRKRNWRYHKTLKAWLTKD 150
>sp|Q12514|NOT5_YEAST General negative regulator of transcription subunit 5 Length = 560 Score = 36.6 bits (83), Expect = 0.018 Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 1/46 (2%) Frame = +2 Query: 107 KLSDETLFWIFYNLTGEECQTTAAKQLMA-RQWRYNKRDKFWLTRD 241 K +TLF+IFY+ G Q AA++L R W +NK D+ W ++ Sbjct: 471 KFDLDTLFFIFYHYQGSYEQFLAARELFKNRNWLFNKVDRCWYYKE 516
>sp|Q64PD6|FMT_BACFR Methionyl-tRNA formyltransferase sp|Q5L975|FMT_BACFN Methionyl-tRNA formyltransferase Length = 324 Score = 28.1 bits (61), Expect = 6.5 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Frame = +2 Query: 14 AGRPHDMDYAVPKEYRIRHSILDKLADPL--PEKLSDE 121 AGR H + Y+ K+Y + H + PL PEKL DE Sbjct: 42 AGRGHKIQYSPVKQYALDHQL------PLLQPEKLKDE 73
>sp|Q58356|TRM1_METJA N(2),N(2)-dimethylguanosine tRNA methyltransferase (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) Length = 374 Score = 28.1 bits (61), Expect = 6.5 Identities = 14/45 (31%), Positives = 25/45 (55%) Frame = +2 Query: 98 LPEKLSDETLFWIFYNLTGEECQTTAAKQLMARQWRYNKRDKFWL 232 +P+KL+ +FYN + C+ + + A Y+KRDKF++ Sbjct: 12 VPDKLTVTKKDEVFYNPRMKTCRDISIAVIQAFLNLYHKRDKFYI 56
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,634,662 Number of Sequences: 369166 Number of extensions: 731899 Number of successful extensions: 1666 Number of sequences better than 10.0: 9 Number of HSP's better than 10.0 without gapping: 1649 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1665 length of database: 68,354,980 effective HSP length: 64 effective length of database: 56,531,940 effective search space used: 1695958200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)