Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_D21
(699 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 precur... 218 2e-56
sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 precur... 218 2e-56
sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 precur... 213 5e-55
sp|P11598|PDIA3_RAT Protein disulfide-isomerase A3 precurso... 211 1e-54
sp|P38658|ERP60_SCHMA Probable protein disulfide-isomerase ... 199 4e-51
sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 precur... 167 3e-41
sp|P38659|PDIA4_RAT Protein disulfide-isomerase A4 precurso... 164 3e-40
sp|P55059|PDI_HUMIN Protein disulfide-isomerase precursor (... 163 4e-40
sp|P08003|PDIA4_MOUSE Protein disulfide-isomerase A4 precur... 163 5e-40
sp|Q12730|PDI_ASPNG Protein disulfide-isomerase precursor (... 148 1e-35
>sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
(58 kDa glucose regulated protein)
Length = 505
Score = 218 bits (554), Expect = 2e-56
Identities = 104/176 (59%), Positives = 131/176 (74%), Gaps = 2/176 (1%)
Frame = +3
Query: 3 LSEFGIESPDSNKVYIVARDEKNQKFKMAEDFTME--AFEKFINDFLNEQVPVYLKSETI 176
LS+FG+ES + R K +KF M E+F+ + A E+F+ D+ + + YLKSE I
Sbjct: 311 LSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPI 370
Query: 177 PEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIV 356
PE ND PVKVVVA+NFD +VN+ KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IV
Sbjct: 371 PESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIV 430
Query: 357 IAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASESTS 524
IAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE+ D + Y+ E+T+
Sbjct: 431 IAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATN 486
Score = 70.9 bits (172), Expect = 3e-12
Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 3/103 (2%)
Frame = +3
Query: 219 NFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-DV 389
NF++ ++D +L+EF+APWCGHCK LAP+YE A +L G + +AK+D TAN +
Sbjct: 34 NFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKG--IVPLAKVDCTANTNT 91
Query: 390 PSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
+ Y V+G+PT+ + +Y+G R D ++ ++ ++
Sbjct: 92 CNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIVSHLKKQA 132
>sp|P38657|PDIA3_BOVIN Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERP60) (58 kDa microsomal protein) (P58) (ERp57)
Length = 505
Score = 218 bits (554), Expect = 2e-56
Identities = 103/176 (58%), Positives = 130/176 (73%), Gaps = 2/176 (1%)
Frame = +3
Query: 3 LSEFGIESPDSNKVYIVARDEKNQKFKMAEDFTME--AFEKFINDFLNEQVPVYLKSETI 176
LS+FG+ES + R K +KF M E+F+ + A E+F+ D+ + + YLKSE I
Sbjct: 311 LSDFGLESTTGEIPVVAVRTAKGEKFVMQEEFSRDGKALERFLEDYFDGNLKRYLKSEPI 370
Query: 177 PEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIV 356
PE ND PVKVVVA+NFD +VN+ KDVLIEFYAPWCGHCK+L PKY+EL +KL + +IV
Sbjct: 371 PESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLRKDPNIV 430
Query: 357 IAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASESTS 524
IAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE+ D + Y+ E+T+
Sbjct: 431 IAKMDATANDVPSPYEVRGFPTIYFSPANKKQNPKKYEGGRELSDFISYLKREATN 486
Score = 72.8 bits (177), Expect = 8e-13
Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 3/103 (2%)
Frame = +3
Query: 219 NFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-DV 389
NF++ + D +L+EF+APWCGHCK LAP+YE A +L G + +AK+D TAN +
Sbjct: 34 NFESRITDTGSSGLMLVEFFAPWCGHCKKLAPEYEAAATRLKG--IVPLAKVDCTANTNT 91
Query: 390 PSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
+ Y V+G+PT+ ++ +Y+G R D ++ ++ ++
Sbjct: 92 CNKYGVSGYPTLKIFRDGEESG--AYDGPRTADGIVSHLKKQA 132
>sp|P27773|PDIA3_MOUSE Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
Length = 504
Score = 213 bits (541), Expect = 5e-55
Identities = 101/176 (57%), Positives = 131/176 (74%), Gaps = 2/176 (1%)
Frame = +3
Query: 3 LSEFGIESPDSNKVYIVARDEKNQKFKMAEDFTME--AFEKFINDFLNEQVPVYLKSETI 176
LS+F +ES + R K +KF M E+F+ + A E+F+ ++ + + YLKSE I
Sbjct: 310 LSDFSLESTTGEVPVVAIRTAKGEKFVMQEEFSRDGKALEQFLQEYFDGNLKRYLKSEPI 369
Query: 177 PEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIV 356
PE N+ PVKVVVA+NFD +VN+ KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IV
Sbjct: 370 PESNEGPVKVVVAENFDDIVNEEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIV 429
Query: 357 IAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASESTS 524
IAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE++D + Y+ E+T+
Sbjct: 430 IAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREATN 485
Score = 68.9 bits (167), Expect = 1e-11
Identities = 37/104 (35%), Positives = 63/104 (60%), Gaps = 3/104 (2%)
Frame = +3
Query: 216 KNFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATAN-D 386
+NF++ V+D +L+EF+APWCGHCK LAP+YE A +L + +AK+D TAN +
Sbjct: 33 ENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRL---KIVPLAKVDCTANTN 89
Query: 387 VPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
+ Y V+G+PT+ + +Y+G R D ++ ++ ++
Sbjct: 90 TCNKYGVSGYPTLKIF--RAGEEAGAYDGPRTADGIVSHLKKQA 131
>sp|P11598|PDIA3_RAT Protein disulfide-isomerase A3 precursor (Disulfide isomerase
ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57)
(HIP-70) (Q-2)
Length = 505
Score = 211 bits (537), Expect = 1e-54
Identities = 101/176 (57%), Positives = 131/176 (74%), Gaps = 2/176 (1%)
Frame = +3
Query: 3 LSEFGIESPDSNKVYIVARDEKNQKFKMAEDFTME--AFEKFINDFLNEQVPVYLKSETI 176
LS+FG+ES + R K +KF M E+F+ + A E+F+ ++ + + YLKSE I
Sbjct: 311 LSDFGLESTTGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQEYFDGNLKRYLKSEPI 370
Query: 177 PEKNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIV 356
PE N+ PVKVVVA++FD +VN KDVLIEFYAPWCGHCK+L PKY+EL +KLS + +IV
Sbjct: 371 PETNEGPVKVVVAESFDDIVNAEDKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIV 430
Query: 357 IAKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASESTS 524
IAKMDATANDVPSPYEV GFPTIYF+P N K +PK Y GGRE++D + Y+ E+T+
Sbjct: 431 IAKMDATANDVPSPYEVKGFPTIYFSPANKKLTPKKYEGGRELNDFISYLQREATN 486
Score = 72.0 bits (175), Expect = 1e-12
Identities = 43/127 (33%), Positives = 73/127 (57%), Gaps = 3/127 (2%)
Frame = +3
Query: 147 VPVYLKSETIPEKNDEPVKVVVAKNFDALVNDPTKD--VLIEFYAPWCGHCKSLAPKYEE 320
V + L S + +D V + +NF++ V+D +L+EF+APWCGHCK LAP+YE
Sbjct: 12 VALLLASALLASASD--VLELTDENFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEA 69
Query: 321 LAKKLSGESDIVIAKMDATAN-DVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDML 497
A +L G + +AK+D TAN + + Y V+G+PT+ + +Y+G R D ++
Sbjct: 70 AATRLKG--IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAG--AYDGPRTADGIV 125
Query: 498 KYIASES 518
++ ++
Sbjct: 126 SHLKKQA 132
>sp|P38658|ERP60_SCHMA Probable protein disulfide-isomerase ER-60 precursor (ERP60)
Length = 484
Score = 199 bits (507), Expect = 4e-51
Identities = 95/190 (50%), Positives = 136/190 (71%)
Frame = +3
Query: 3 LSEFGIESPDSNKVYIVARDEKNQKFKMAEDFTMEAFEKFINDFLNEQVPVYLKSETIPE 182
+S++GIE+ +K+ V K++K+K+ E F+++AF F+N F + + ++KSE +P
Sbjct: 299 ISDYGIEA---DKLPAVVIQSKDKKYKL-EKFSLDAFSDFLNKFEDGLLTPHVKSEPLPT 354
Query: 183 KNDEPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIA 362
+ VK +VA NFD +VN+ KDV++ F+A WCGHCK+L PKYEE A K+ E ++V+A
Sbjct: 355 DDSSAVKKLVALNFDEIVNNEEKDVMVVFHAGWCGHCKNLMPKYEEAASKVKNEPNLVLA 414
Query: 363 KMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASESTSSLKSYD 542
MDATANDVPSPY+V GFPTIYF PK K+SP SY GGR+ +D++KY+A E+T L YD
Sbjct: 415 AMDATANDVPSPYQVRGFPTIYFVPKGKKSSPVSYEGGRDTNDIIKYLAREATEELIGYD 474
Query: 543 RQGRVRKSDL 572
R G +KS+L
Sbjct: 475 RSGNPKKSEL 484
Score = 67.4 bits (163), Expect = 3e-11
Identities = 32/89 (35%), Positives = 54/89 (60%), Gaps = 2/89 (2%)
Frame = +3
Query: 258 LIEFYAPWCGHCKSLAPKYEELAKKLSGE-SDIVIAKMDATAND-VPSPYEVTGFPTIYF 431
L++FYAPWCGHCK LAP++ A+ +SG+ +D+ + K+D T + + S + V+G+PT+
Sbjct: 38 LVKFYAPWCGHCKKLAPEFTSAAQIISGKTNDVKLVKVDCTTQESICSEFGVSGYPTLKI 97
Query: 432 APKNSKNSPKSYNGGREVDDMLKYIASES 518
+ YNG R + + Y+ S +
Sbjct: 98 FRNGDLDG--EYNGPRNANGIANYMISRA 124
>sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
Length = 645
Score = 167 bits (422), Expect = 3e-41
Identities = 82/157 (52%), Positives = 106/157 (67%), Gaps = 3/157 (1%)
Frame = +3
Query: 60 DEKNQKFKMA-EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALV 236
DE +KF M E+F + +F+ F ++ +KS+ +P+ N PVKVVV K FD++V
Sbjct: 480 DESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIV 539
Query: 237 NDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSP-YEVTG 413
DP KDVLIEFYAPWCGHCK L P Y LAKK G+ +VIAKMDATANDVPS Y+V G
Sbjct: 540 MDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEG 599
Query: 414 FPTIYFAPKNSKNSPKSYNGG-REVDDMLKYIASEST 521
FPTIYFAP K +P + GG R+++ + K+I +T
Sbjct: 600 FPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHAT 636
Score = 92.8 bits (229), Expect = 8e-19
Identities = 51/111 (45%), Positives = 71/111 (63%), Gaps = 2/111 (1%)
Frame = +3
Query: 192 EPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKM 368
E V+ +NFD +VND +L+EFYAPWCGHCK LAP+YE+ AK+LS S I +AK+
Sbjct: 177 EVTLVLTKENFDEVVND-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 235
Query: 369 DATA-NDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
DATA D+ ++V+G+PT+ K P YNG RE ++ Y+ +S
Sbjct: 236 DATAETDLAKRFDVSGYPTLKIF---RKGRPYDYNGpreKYGIVDYMIEQS 283
Score = 76.6 bits (187), Expect = 6e-14
Identities = 47/122 (38%), Positives = 70/122 (57%), Gaps = 3/122 (2%)
Frame = +3
Query: 162 KSETIPEKNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKLS 338
+ + + K + V V+ NFD V D KD VL+EFYAPWCGHCK AP+YE++A L
Sbjct: 52 EEDDLEVKEENGVLVLNDANFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIANILK 109
Query: 339 G-ESDIVIAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIAS 512
+ I +AK+DAT A+ + S ++V+G+PTI K Y G R ++++ +
Sbjct: 110 DKDPPIPVAKIDATSASVLASRFDVSGYPTIKIL---KKGQAVDYEGSRTQEEIVAKVRE 166
Query: 513 ES 518
S
Sbjct: 167 VS 168
>sp|P38659|PDIA4_RAT Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
(Calcium-binding protein 2) (CaBP2)
Length = 643
Score = 164 bits (414), Expect = 3e-40
Identities = 80/157 (50%), Positives = 107/157 (68%), Gaps = 3/157 (1%)
Frame = +3
Query: 60 DEKNQKFKMA-EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALV 236
DE +KF M E+F +A ++F+ F ++ +KS+ +P+ N PV+VVV K FDA+V
Sbjct: 478 DESGKKFAMEPEEFDSDALQEFVMAFKKGKLKPVIKSQPVPKNNKGPVRVVVGKTFDAIV 537
Query: 237 NDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPSP-YEVTG 413
DP KDVLIEFYAPWCGHCK L P Y L KK G+ D+VIAKMDATAND+ + Y+V G
Sbjct: 538 MDPKKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQKDLVIAKMDATANDITNDRYKVEG 597
Query: 414 FPTIYFAPKNSKNSPKSYNGG-REVDDMLKYIASEST 521
FPTIYFAP K +P + GG R+++ + K+I +T
Sbjct: 598 FPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHAT 634
Score = 87.0 bits (214), Expect = 4e-17
Identities = 48/111 (43%), Positives = 69/111 (62%), Gaps = 2/111 (1%)
Frame = +3
Query: 192 EPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKM 368
E + +NFD +VN+ +L+EFYAPWCGHCK LAP+YE+ AK+LS S I +AK+
Sbjct: 175 EVTLTLTKENFDDVVNN-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 233
Query: 369 DAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
DAT D+ ++V+G+PT+ K P YNG RE ++ Y+ +S
Sbjct: 234 DATEQTDLAKRFDVSGYPTLKIF---RKGRPFDYNGpreKYGIVDYMVEQS 281
Score = 79.3 bits (194), Expect = 9e-15
Identities = 47/115 (40%), Positives = 69/115 (60%), Gaps = 3/115 (2%)
Frame = +3
Query: 183 KNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SGESDIV 356
K + V V+ +NFD V D KD VL+EFYAPWCGHCK AP+YE++A L + I
Sbjct: 57 KEENGVWVLNDENFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIA 114
Query: 357 IAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
+AK+DAT A+ + S ++V+G+PTI K Y+G R ++++ + S
Sbjct: 115 VAKIDATSASMLASKFDVSGYPTIKIL---KKGQAVDYDGSRTQEEIVAKVREVS 166
>sp|P55059|PDI_HUMIN Protein disulfide-isomerase precursor (PDI)
Length = 505
Score = 163 bits (413), Expect = 4e-40
Identities = 84/165 (50%), Positives = 111/165 (67%), Gaps = 5/165 (3%)
Frame = +3
Query: 30 DSNKVYIVARDEKNQKFKMAED--FTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVK 203
D + + KNQKF ++ T EA + F++DF+ ++ +KSE IPEK + PV
Sbjct: 299 DKFPAFAIQEVAKNQKFPFDQEKEITFEAIKAFVDDFVAGKIEPSIKSEPIPEKQEGPVT 358
Query: 204 VVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELA---KKLSGESDIVIAKMDA 374
VVVAKN++ +V D TKDVLIEFYAPWCGHCK+LAPKYEEL K + +VIAK+DA
Sbjct: 359 VVVAKNYNEIVLDDTKDVLIEFYAPWCGHCKALAPKYEELGALYAKSEFKDRVVIAKVDA 418
Query: 375 TANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIA 509
TANDVP E+ GFPTI P +K P +Y+G R V+D++K+IA
Sbjct: 419 TANDVPD--EIQGFPTIKLYPAGAKGQPVTYSGSRTVEDLIKFIA 461
Score = 68.2 bits (165), Expect = 2e-11
Identities = 44/117 (37%), Positives = 64/117 (54%), Gaps = 3/117 (2%)
Frame = +3
Query: 255 VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDAT-ANDVPSPYEVTGFPTIYF 431
VL EF+APWCGHCK+LAP+YEE A L E +I +AK+D T D+ + V G+PT+
Sbjct: 41 VLAEFFAPWCGHCKALAPEYEEAATTLK-EKNIKLAKVDCTEETDLCQQHGVEGYPTLKV 99
Query: 432 APKNSKNSPKSYNGGREVDDMLKYIASESTSSLK--SYDRQGRVRKSDL*KIKIVEY 596
SP Y G R+ + Y+ +S ++ + D +K+D K +V Y
Sbjct: 100 FRGLDNVSP--YKGQRKAAAITSYMIKQSLPAVSEVTKDNLEEFKKAD--KAVLVAY 152
>sp|P08003|PDIA4_MOUSE Protein disulfide-isomerase A4 precursor (Protein ERp-72) (ERp72)
Length = 638
Score = 163 bits (412), Expect = 5e-40
Identities = 80/157 (50%), Positives = 105/157 (66%), Gaps = 3/157 (1%)
Frame = +3
Query: 60 DEKNQKFKMA-EDFTMEAFEKFINDFLNEQVPVYLKSETIPEKNDEPVKVVVAKNFDALV 236
DE +KF M E+F + +F+ F ++ +KS+ +P+ N PVKVVV K FDA+V
Sbjct: 473 DESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDAIV 532
Query: 237 NDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATANDVPS-PYEVTG 413
DP KDVLIEFYAPWCGHCK L P Y L KK G+ D+VIAKMDATAND+ + Y+V G
Sbjct: 533 MDPKKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQKDLVIAKMDATANDITNDQYKVEG 592
Query: 414 FPTIYFAPKNSKNSPKSYNGG-REVDDMLKYIASEST 521
FPTIYFAP K +P + GG R+++ + K+I +T
Sbjct: 593 FPTIYFAPSGDKKNPIKFEGGNRDLEHLSKFIDEHAT 629
Score = 85.9 bits (211), Expect = 9e-17
Identities = 47/102 (46%), Positives = 66/102 (64%), Gaps = 2/102 (1%)
Frame = +3
Query: 219 NFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGES-DIVIAKMDAT-ANDVP 392
NFD +VN+ +L+EFYAPWCGHCK LAP+YE+ AK+LS S I +AK+DAT D+
Sbjct: 179 NFDDVVNN-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLA 237
Query: 393 SPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
++V+G+PT+ K P YNG RE ++ Y+ +S
Sbjct: 238 KRFDVSGYPTLKIF---RKGRPFDYNGpreKYGIVDYMIEQS 276
Score = 78.2 bits (191), Expect = 2e-14
Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 3/115 (2%)
Frame = +3
Query: 183 KNDEPVKVVVAKNFDALVNDPTKD-VLIEFYAPWCGHCKSLAPKYEELAKKL-SGESDIV 356
K + V V+ NFD V D KD VL+EFYAPWCGHCK AP+YE++A L + I
Sbjct: 52 KEENGVWVLNDGNFDNFVAD--KDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIA 109
Query: 357 IAKMDAT-ANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYIASES 518
+AK+DAT A+ + S ++V+G+PTI K Y+G R ++++ + S
Sbjct: 110 VAKIDATSASMLASKFDVSGYPTIKIL---KKGQAVDYDGSRTQEEIVAKVREVS 161
>sp|Q12730|PDI_ASPNG Protein disulfide-isomerase precursor (PDI)
Length = 515
Score = 148 bits (374), Expect = 1e-35
Identities = 77/169 (45%), Positives = 104/169 (61%), Gaps = 4/169 (2%)
Frame = +3
Query: 12 FGIESPDSNKVYIVARDEKNQKFKMAEDFTMEAFEKFINDFLNEQVPVYLKSETIPEKND 191
F I+ P N Y + A++ + EKFI D L+ +V +KSE +PE +
Sbjct: 308 FAIQDPAKNAKY---------PYDQAKELNADEVEKFIQDVLDGKVEPSIKSEPVPESQE 358
Query: 192 EPVKVVVAKNFDALVNDPTKDVLIEFYAPWCGHCKSLAPKYEELAKKLSGESD----IVI 359
PV VVVA ++ LV D KDVL+EFYAPWCGHCK+LAPKY+ELA + D + I
Sbjct: 359 GPVTVVVAHSYKDLVIDNDKDVLLEFYAPWCGHCKALAPKYDELAALYADHPDLAAKVTI 418
Query: 360 AKMDATANDVPSPYEVTGFPTIYFAPKNSKNSPKSYNGGREVDDMLKYI 506
AK+DATANDVP P +TGFPT+ P +K+SP Y+G R V+D+ ++
Sbjct: 419 AKIDATANDVPDP--ITGFPTLRLYPAGAKDSPIEYSGSRTVEDLANFV 465
Score = 79.0 bits (193), Expect = 1e-14
Identities = 42/115 (36%), Positives = 66/115 (57%), Gaps = 1/115 (0%)
Frame = +3
Query: 255 VLIEFYAPWCGHCKSLAPKYEELAKKLSGESDIVIAKMDATA-NDVPSPYEVTGFPTIYF 431
VL EF+APWCGHCK+LAPKYEE A +L + +I + K+D TA D+ V G+PT+
Sbjct: 45 VLAEFFAPWCGHCKALAPKYEEAATELKAK-NIPLVKVDCTAEEDLCRSQGVEGYPTLKI 103
Query: 432 APKNSKNSPKSYNGGREVDDMLKYIASESTSSLKSYDRQGRVRKSDL*KIKIVEY 596
+S K Y G R+ + ++ Y+ +S ++ S + + + KI ++ Y
Sbjct: 104 F--RGVDSSKPYQGARQTESIVSYMIKQSLPAVSSVNEENLEEIKTMDKIVVIGY 156
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,145,397
Number of Sequences: 369166
Number of extensions: 1539171
Number of successful extensions: 5107
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4815
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5013
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6073541875
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)