Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_D09
(562 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A... 238 8e-63
sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eI... 237 2e-62
sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eI... 237 2e-62
sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eI... 237 2e-62
sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eI... 235 5e-62
sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (e... 235 6e-62
sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (e... 235 6e-62
sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A... 226 3e-59
sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A... 226 3e-59
sp|P38919|DDX48_HUMAN Probable ATP-dependent helicase DDX48... 224 9e-59
>sp|P47943|IF4A_SCHPO Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 392
Score = 238 bits (607), Expect = 8e-63
Identities = 117/166 (70%), Positives = 136/166 (81%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGI+QFYV V +E++K +TL DLYET+T+TQAVIFCNTRRKVD+LTE L + F VS
Sbjct: 227 LTLEGIKQFYVAVEKEEWKLDTLCDLYETVTVTQAVIFCNTRRKVDWLTEQLTERDFTVS 286
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
SMHGDM Q RD +M EFR+GSSRILITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 287 SMHGDMDQAQRDTLMHEFRTGSSRILITTDLLARGIDVQQVSLVINYDLPANRENYIHRI 346
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
V+INFVT DD+R ++++E +Y+THIEEMPMNIADLI
Sbjct: 347 GRGGRFGRKGVSINFVTNDDVRMMREIEQFYNTHIEEMPMNIADLI 392
>sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
sp|P60843|IF4A1_MOUSE Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 237 bits (604), Expect = 2e-62
Identities = 118/166 (71%), Positives = 137/166 (82%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE + A+ F VS
Sbjct: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
>sp|Q5R5F5|IF4A1_PONPY Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 237 bits (604), Expect = 2e-62
Identities = 118/166 (71%), Positives = 137/166 (82%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE + A+ F VS
Sbjct: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
>sp|P29562|IF4A1_RABIT Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 398
Score = 237 bits (604), Expect = 2e-62
Identities = 118/166 (71%), Positives = 137/166 (82%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE + A+ F VS
Sbjct: 233 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 292
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 293 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 352
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 353 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 398
>sp|Q4R8K5|IF4A1_MACFA Eukaryotic initiation factor 4A-I (eIF4A-I) (eIF-4A-I)
Length = 406
Score = 235 bits (600), Expect = 5e-62
Identities = 117/166 (70%), Positives = 136/166 (81%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGIRQFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE + A+ F S
Sbjct: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTAS 300
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
+MHGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAIN VT++D RTL+D+E++Y+T IEEMP+N+ADLI
Sbjct: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
>sp|P10630|IF4A2_MOUSE Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q14240|IF4A2_HUMAN Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
sp|Q5R4X1|IF4A2_PONPY Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 407
Score = 235 bits (599), Expect = 6e-62
Identities = 116/166 (69%), Positives = 137/166 (82%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGI+QFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE + A+ F VS
Sbjct: 242 LTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVS 301
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
++HGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 302 ALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 361
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAINFVT++D R L+D+E++Y+T +EEMPMN+ADLI
Sbjct: 362 GRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
>sp|Q4R4Y9|IF4A2_MACFA Eukaryotic initiation factor 4A-II (eIF4A-II) (eIF-4A-II)
Length = 408
Score = 235 bits (599), Expect = 6e-62
Identities = 116/166 (69%), Positives = 137/166 (82%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGI+QFY+NV E++K +TL DLYETLTITQAVIF NTRRKVD+LTE + A+ F VS
Sbjct: 243 LTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVS 302
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
++HGDM Q RD IM+EFRSGSSR+LITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 303 ALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 362
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAINFVT++D R L+D+E++Y+T +EEMPMN+ADLI
Sbjct: 363 GRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 408
>sp|P27639|IF4A_CAEEL Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 402
Score = 226 bits (576), Expect = 3e-59
Identities = 112/166 (67%), Positives = 132/166 (79%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGIRQFY+NV ++++KF+ L DLY + +TQAVIFCNTRRKVD LTE + QF VS
Sbjct: 237 LTLEGIRQFYINVQKDEWKFDCLCDLYNVVNVTQAVIFCNTRRKVDTLTEKMTENQFTVS 296
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
+HGDM Q RD IM+EFRSGSSR+LITTD+LARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 297 CLHGDMDQAERDTIMREFRSGSSRVLITTDILARGIDVQQVSLVINYDLPSNRENYIHRI 356
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAINFVT++D R L+++ESYY+T IEEMP +IADLI
Sbjct: 357 GRSGRFGRKGVAINFVTENDARQLKEIESYYTTQIEEMPESIADLI 402
>sp|Q02748|IF4A_DROME Eukaryotic initiation factor 4A (eIF4A) (eIF-4A)
Length = 403
Score = 226 bits (576), Expect = 3e-59
Identities = 114/166 (68%), Positives = 132/166 (79%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGI+QFYVNV +E++K TL DLY+TL+ITQ+VIFCNTRRKVD LT+ + F VS
Sbjct: 238 LTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQSVIFCNTRRKVDQLTQEMSIHNFTVS 297
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
+MHGDM+Q R+ IMK+FRSGSSR+LITTDLLARGIDVQQVSLVINYDLP NRENYIH
Sbjct: 298 AMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRI 357
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAINF+T DD R L+D+E +Y T IEEMP NIADLI
Sbjct: 358 GRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIADLI 403
>sp|P38919|DDX48_HUMAN Probable ATP-dependent helicase DDX48 (DEAD-box protein 48)
(Eukaryotic initiation factor 4A-like NUK-34) (Nuclear
matrix protein 265) (hNMP 265) (Eukaryotic translation
initiation factor 4A isoform 3)
Length = 411
Score = 224 bits (572), Expect = 9e-59
Identities = 111/166 (66%), Positives = 132/166 (79%)
Frame = +3
Query: 3 LTLEGIRQFYVNVSEEDYKFETLTDLYETLTITQAVIFCNTRRKVDYLTESLKAKQFIVS 182
LTLEGI+QF+V V E++KF+TL DLY+TLTITQAVIFCNT+RKVD+LTE ++ F VS
Sbjct: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS 305
Query: 183 SMHGDMQQDMRDQIMKEFRSGSSRILITTDLLARGIDVQQVSLVINYDLPLNRENYIHXX 362
SMHGDM Q R+ IMKEFRSG+SR+LI+TD+ ARG+DV QVSL+INYDLP NRE YIH
Sbjct: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365
Query: 363 XXXXXXXXXXVAINFVTQDDIRTLQDLESYYSTHIEEMPMNIADLI 500
VAINFV DDIR L+D+E YYST I+EMPMN+ADLI
Sbjct: 366 GRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,559,854
Number of Sequences: 369166
Number of extensions: 920886
Number of successful extensions: 2485
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2422
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2453
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4029688280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)