Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_D07
(359 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P83917|CBX1_MOUSE Chromobox protein homolog 1 (Heterochr... 119 2e-27
sp|Q61686|CBX5_MOUSE Chromobox protein homolog 5 (Heterochr... 111 4e-25
sp|P45973|CBX5_HUMAN Chromobox protein homolog 5 (Heterochr... 110 1e-24
sp|Q5R6X7|CBX3_PONPY Chromobox protein homolog 3 (Heterochr... 108 3e-24
sp|P23198|CBX3_MOUSE Chromobox protein homolog 3 (Heterochr... 108 3e-24
sp|Q13185|CBX3_HUMAN Chromobox protein homolog 3 (Heterochr... 106 1e-23
sp|P29227|HP1_DROVI Heterochromatin protein 1 (HP1) 89 4e-18
sp|P05205|HP1_DROME Heterochromatin protein 1 (HP1) (Nonhis... 86 3e-17
sp|P40381|SWI6_SCHPO Chromatin-associated swi6 protein 33 0.15
sp|P47134|BIR1_YEAST Protein BIR1 30 2.2
>sp|P83917|CBX1_MOUSE Chromobox protein homolog 1 (Heterochromatin protein 1 homolog
beta) (HP1 beta) (Modifier 1 protein) (M31)
(Heterochromatin protein p25)
sp|P83916|CBX1_HUMAN Chromobox protein homolog 1 (Heterochromatin protein 1 homolog
beta) (HP1 beta) (Modifier 1 protein) (M31)
(Heterochromatin protein p25) (HP1Hsbeta) (p25beta)
Length = 185
Score = 119 bits (298), Expect = 2e-27
Identities = 54/81 (66%), Positives = 70/81 (86%)
Frame = +3
Query: 30 EKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVV 209
+K K ++ + +GF+RGLE ++IIGATDS+GELMFL+KWKNS+EADLVPA+EANVKCPQVV
Sbjct: 101 KKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVV 160
Query: 210 IKFYEERLTWHTPTNATTNEK 272
I FYEERLTWH+ + ++K
Sbjct: 161 ISFYEERLTWHSYPSEDDDKK 181
Score = 35.8 bits (81), Expect = 0.031
Identities = 14/52 (26%), Positives = 28/52 (53%)
Frame = +3
Query: 87 DKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVVIKFYEERLTWH 242
+K++ G++ +L+KWK + D E N+ CP ++ +F + + T H
Sbjct: 24 EKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAH 75
>sp|Q61686|CBX5_MOUSE Chromobox protein homolog 5 (Heterochromatin protein 1 homolog
alpha) (HP1 alpha)
Length = 191
Score = 111 bits (278), Expect = 4e-25
Identities = 54/88 (61%), Positives = 71/88 (80%), Gaps = 1/88 (1%)
Frame = +3
Query: 21 KTEEKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCP 200
K+++K + + ++GF RGLE +KIIGATDS G+LMFL+KWK+++EADLV A+EANVKCP
Sbjct: 102 KSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCP 161
Query: 201 QVVIKFYEERLTWHT-PTNATTNEKVSS 281
Q+VI FYEERLTWH P +A EK S+
Sbjct: 162 QIVIAFYEERLTWHAYPEDAENKEKESA 189
Score = 32.0 bits (71), Expect = 0.45
Identities = 15/62 (24%), Positives = 29/62 (46%)
Frame = +3
Query: 87 DKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVVIKFYEERLTWHTPTNATTN 266
+K++ G++ +L+KWK E E N+ CP+++ +F ++ N
Sbjct: 23 EKVLDRRMVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPR 82
Query: 267 EK 272
EK
Sbjct: 83 EK 84
>sp|P45973|CBX5_HUMAN Chromobox protein homolog 5 (Heterochromatin protein 1 homolog
alpha) (HP1 alpha) (Antigen p25)
Length = 191
Score = 110 bits (275), Expect = 1e-24
Identities = 53/85 (62%), Positives = 69/85 (81%), Gaps = 1/85 (1%)
Frame = +3
Query: 21 KTEEKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCP 200
K+++K + + ++GF RGLE +KIIGATDS G+LMFL+KWK+++EADLV A+EANVKCP
Sbjct: 102 KSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCP 161
Query: 201 QVVIKFYEERLTWHT-PTNATTNEK 272
Q+VI FYEERLTWH P +A EK
Sbjct: 162 QIVIAFYEERLTWHAYPEDAENKEK 186
Score = 32.7 bits (73), Expect = 0.26
Identities = 16/65 (24%), Positives = 30/65 (46%)
Frame = +3
Query: 87 DKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVVIKFYEERLTWHTPTNATTN 266
+K++ G++ +L+KWK E E N+ CP+++ +F ++ N
Sbjct: 23 EKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPR 82
Query: 267 EKVSS 281
EK S
Sbjct: 83 EKSES 87
>sp|Q5R6X7|CBX3_PONPY Chromobox protein homolog 3 (Heterochromatin protein 1 homolog
gamma) (HP1 gamma)
Length = 183
Score = 108 bits (271), Expect = 3e-24
Identities = 48/72 (66%), Positives = 65/72 (90%)
Frame = +3
Query: 30 EKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVV 209
+K + A++ +GF+RGL+ ++IIGATDS+GELMFL+KWK+S+EADLV A+EAN+KCPQ+V
Sbjct: 105 KKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIV 164
Query: 210 IKFYEERLTWHT 245
I FYEERLTWH+
Sbjct: 165 IAFYEERLTWHS 176
Score = 35.4 bits (80), Expect = 0.040
Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Frame = +3
Query: 27 EEKGKVQANRSKGFSRG----LEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVK 194
++ GK Q +SK +K++ NG++ + +KWK +AD E N+
Sbjct: 9 QKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLD 68
Query: 195 CPQVVIKF 218
CP+++ F
Sbjct: 69 CPELIEAF 76
>sp|P23198|CBX3_MOUSE Chromobox protein homolog 3 (Heterochromatin protein 1 homolog
gamma) (HP1 gamma) (Modifier 2 protein) (M32)
Length = 183
Score = 108 bits (271), Expect = 3e-24
Identities = 48/72 (66%), Positives = 65/72 (90%)
Frame = +3
Query: 30 EKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVV 209
+K + A++ +GF+RGL+ ++IIGATDS+GELMFL+KWK+S+EADLV A+EAN+KCPQ+V
Sbjct: 105 KKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIV 164
Query: 210 IKFYEERLTWHT 245
I FYEERLTWH+
Sbjct: 165 IAFYEERLTWHS 176
Score = 35.4 bits (80), Expect = 0.040
Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Frame = +3
Query: 27 EEKGKVQANRSKGFSRG----LEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVK 194
++ GK Q +SK +K++ NG++ + +KWK +AD E N+
Sbjct: 9 QKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLD 68
Query: 195 CPQVVIKF 218
CP+++ F
Sbjct: 69 CPELIEDF 76
>sp|Q13185|CBX3_HUMAN Chromobox protein homolog 3 (Heterochromatin protein 1 homolog
gamma) (HP1 gamma) (Modifier 2 protein) (HECH)
Length = 183
Score = 106 bits (265), Expect = 1e-23
Identities = 47/72 (65%), Positives = 64/72 (88%)
Frame = +3
Query: 30 EKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVV 209
+K + A++ +GF+RGL+ ++IIGA DS+GELMFL+KWK+S+EADLV A+EAN+KCPQ+V
Sbjct: 105 KKKRDAADKPRGFARGLDPERIIGAIDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIV 164
Query: 210 IKFYEERLTWHT 245
I FYEERLTWH+
Sbjct: 165 IAFYEERLTWHS 176
Score = 35.4 bits (80), Expect = 0.040
Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Frame = +3
Query: 27 EEKGKVQANRSKGFSRG----LEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVK 194
++ GK Q +SK +K++ NG++ + +KWK +AD E N+
Sbjct: 9 QKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLD 68
Query: 195 CPQVVIKF 218
CP+++ F
Sbjct: 69 CPELIEAF 76
>sp|P29227|HP1_DROVI Heterochromatin protein 1 (HP1)
Length = 213
Score = 88.6 bits (218), Expect = 4e-18
Identities = 39/75 (52%), Positives = 59/75 (78%)
Frame = +3
Query: 21 KTEEKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCP 200
++E+ G + GF RGLEA+KI+GA+D+NG L FLI++K ++A++VP+ ANVK P
Sbjct: 135 ESEDTGDIVPAGGTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSTVANVKIP 194
Query: 201 QVVIKFYEERLTWHT 245
Q+VI+FYEERL+W++
Sbjct: 195 QMVIRFYEERLSWYS 209
>sp|P05205|HP1_DROME Heterochromatin protein 1 (HP1) (Nonhistone chromosomal protein
C1A9 antigen)
Length = 206
Score = 85.9 bits (211), Expect = 3e-17
Identities = 41/86 (47%), Positives = 63/86 (73%), Gaps = 5/86 (5%)
Frame = +3
Query: 3 TAPAPKKTE-----EKGKVQANRSKGFSRGLEADKIIGATDSNGELMFLIKWKNSEEADL 167
TAP+ K++ E+ + + S GF RGLEA+KI+GA+D+NG L FLI++K ++A++
Sbjct: 117 TAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEM 176
Query: 168 VPAREANVKCPQVVIKFYEERLTWHT 245
VP+ AN K P++VI FYEERL+W++
Sbjct: 177 VPSSVANEKIPRMVIHFYEERLSWYS 202
Score = 28.5 bits (62), Expect = 4.9
Identities = 19/69 (27%), Positives = 33/69 (47%)
Frame = +3
Query: 87 DKIIGATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVVIKFYEERLTWHTPTNATTN 266
+KII G++ + +KWK E + E N+ C Q +I+ YE + A+
Sbjct: 27 EKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDC-QDLIQQYEASRKDEEKSAASKK 85
Query: 267 EKVSSTGDA 293
++ SS+ A
Sbjct: 86 DRPSSSAKA 94
>sp|P40381|SWI6_SCHPO Chromatin-associated swi6 protein
Length = 328
Score = 33.5 bits (75), Expect = 0.15
Identities = 16/42 (38%), Positives = 24/42 (57%)
Frame = +3
Query: 114 NGELMFLIKWKNSEEADLVPAREANVKCPQVVIKFYEERLTW 239
+G L + WKN + P+ N KCPQ +++FYE LT+
Sbjct: 284 DGTLEIYLTWKNGAISHH-PSTITNKKCPQKMLQFYESHLTF 324
>sp|P47134|BIR1_YEAST Protein BIR1
Length = 954
Score = 29.6 bits (65), Expect = 2.2
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 8/59 (13%)
Frame = +3
Query: 102 ATDSNGELMFLIKWKNSEEADLVPAREANVKCPQVVIKFYEE--------RLTWHTPTN 254
A D +G+L FLIK +EE D+ N+K + +F ++ R ++T TN
Sbjct: 875 ANDKDGDLAFLIKQMPAEELDMTFNNWVNLKVQSIKREFIDDCDKKLDILRRDYYTATN 933
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,037,474
Number of Sequences: 369166
Number of extensions: 640692
Number of successful extensions: 1512
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1487
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1511
length of database: 68,354,980
effective HSP length: 87
effective length of database: 52,283,035
effective search space used: 1673057120
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)