Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_D05
(895 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UNW9|NOVA2_HUMAN RNA-binding protein Nova-2 (Neuro-onc... 73 9e-13
sp|Q80WA4|NOVA1_RAT RNA-binding protein Nova-1 (Neuro-oncol... 71 4e-12
sp|Q9JKN6|NOVA1_MOUSE RNA-binding protein Nova-1 (Neuro-onc... 70 6e-12
sp|P51513|NOVA1_HUMAN RNA-binding protein Nova-1 (Neuro-onc... 70 8e-12
sp|P57722|PCBP3_MOUSE Poly(rC)-binding protein 3 (Alpha-CP3) 64 6e-10
sp|P57721|PCBP3_HUMAN Poly(rC)-binding protein 3 (Alpha-CP3) 64 6e-10
sp|Q61990|PCBP2_MOUSE Poly(rC)-binding protein 2 (Alpha-CP2... 60 8e-09
sp|P60335|PCBP1_MOUSE Poly(rC)-binding protein 1 (Alpha-CP1... 59 2e-08
sp|Q15366|PCBP2_HUMAN Poly(rC)-binding protein 2 (Alpha-CP2... 57 5e-08
sp|P57723|PCBP4_HUMAN Poly(rC)-binding protein 4 (Alpha-CP4) 52 3e-06
>sp|Q9UNW9|NOVA2_HUMAN RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2)
(Astrocytic NOVA1-like RNA-binding protein)
Length = 492
Score = 73.2 bits (178), Expect = 9e-13
Identities = 36/93 (38%), Positives = 55/93 (59%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
K+I+PNS+AGL+IGK G T+ + + +GA++Q+S K ER V V G+ Q H+A
Sbjct: 134 KLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGEPEQVHKAV 193
Query: 183 KKIINKVVEDTKLCSFPNINYNEIINATSYTIP 281
I+ KV ED + S NI+Y + + + P
Sbjct: 194 SAIVQKVQEDPQSSSCLNISYANVAGPVANSNP 226
Score = 53.1 bits (126), Expect = 1e-06
Identities = 35/99 (35%), Positives = 54/99 (54%)
Frame = +3
Query: 465 FSQMDYIASDSSHGITRTLEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDK 644
F + +A++S+ + + V E +GAILG G+++VE QE+T I++SKK
Sbjct: 394 FLTAEKLAAESAKELVE-IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGT 452
Query: 645 NNKRIVTITGLYENVSKAYLLINDKIQLEQARRAMASQE 761
N+R VTITG A LI+ ++ EQ RA Q+
Sbjct: 453 RNRR-VTITGSPAATQAAQYLISQRVTYEQGVRASNPQK 490
Score = 43.5 bits (101), Expect = 8e-04
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS-PKSNNRQFLERYVLVMGDSHQCHEA 179
K++IP+ +AG +IGK G+TI ++K TGA I++S K ER LV G + +
Sbjct: 36 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNAV 95
Query: 180 TKKIINKVVEDTKLCSFPNI 239
I KV E + + P +
Sbjct: 96 HSFIAEKVREIPQAMTKPEV 115
Score = 33.5 bits (75), Expect = 0.82
Identities = 14/36 (38%), Positives = 25/36 (69%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPK 110
+I +P + G ++GK G+T+ + ++ TGA IQ+S K
Sbjct: 410 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 445
Score = 32.7 bits (73), Expect = 1.4
Identities = 21/69 (30%), Positives = 36/69 (52%)
Frame = +3
Query: 519 LEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKA 698
L V + G I+G G ++ + E + +++S+KP +R+VT++G E V KA
Sbjct: 135 LIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP--EGINLQERVVTVSGEPEQVHKA 192
Query: 699 YLLINDKIQ 725
I K+Q
Sbjct: 193 VSAIVQKVQ 201
>sp|Q80WA4|NOVA1_RAT RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1)
Length = 474
Score = 71.2 bits (173), Expect = 4e-12
Identities = 44/126 (34%), Positives = 67/126 (53%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
KII+PNS+AGL+IGK G T+ I + +GA++Q+S K + ER V V G+ Q +A
Sbjct: 150 KIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 209
Query: 183 KKIINKVVEDTKLCSFPNINYNEIINATSYTIPDYFGVPIGTTPYNHTNSFENSTFSYSG 362
+ II K+ ED + S NI+Y + + + P F PY +T + + +G
Sbjct: 210 ELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGF-------PYANTAEVLPTAAAAAG 262
Query: 363 NNFHMN 380
H N
Sbjct: 263 LLGHAN 268
Score = 54.3 bits (129), Expect = 5e-07
Identities = 38/110 (34%), Positives = 54/110 (49%)
Frame = +3
Query: 414 TPGTNSHFPVSRSLTTSFSQMDYIASDSSHGITRTLEVNETYIGAILGAKGRSIVELQEV 593
T TN +F + L S ++D S + + V E +GAILG G+++VE QE+
Sbjct: 367 TAATNGYFGAASPLAASAILGTEKSTDGSKDVVE-IAVPENLVGAILGKGGKTLVEYQEL 425
Query: 594 TDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKAYLLINDKIQLEQARR 743
T I++SKK N++ VTITG A LI +I EQ R
Sbjct: 426 TGARIQISKKGEFVPGTRNRK-VTITGTPAATQAAQYLITQRITYEQGVR 474
Score = 39.7 bits (91), Expect = 0.011
Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS-PKSNNRQFLERYVLVMGDSHQCHEA 179
K++IP+ +AG +IGK G+TI ++K TGA I++S K ER L+ G +
Sbjct: 52 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAV 111
Query: 180 TKKIINKVVE 209
I K+ E
Sbjct: 112 HGFIAEKIRE 121
Score = 33.5 bits (75), Expect = 0.82
Identities = 14/36 (38%), Positives = 25/36 (69%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPK 110
+I +P + G ++GK G+T+ + ++ TGA IQ+S K
Sbjct: 400 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 435
Score = 32.3 bits (72), Expect = 1.8
Identities = 20/61 (32%), Positives = 34/61 (55%)
Frame = +3
Query: 543 GAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKAYLLINDKI 722
G I+G G ++ + E + +++S+KP + +R+VT++G E KA LI KI
Sbjct: 159 GLIIGKGGATVKAIMEQSGAWVQLSQKP--DGINLQERVVTVSGEPEQNRKAVELIIQKI 216
Query: 723 Q 725
Q
Sbjct: 217 Q 217
>sp|Q9JKN6|NOVA1_MOUSE RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1)
(Ventral neuron-specific protein 1)
Length = 493
Score = 70.5 bits (171), Expect = 6e-12
Identities = 40/103 (38%), Positives = 59/103 (57%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
KII+PNS+AGL+IGK G T+ I + +GA++Q+S K + ER V V G+ Q +A
Sbjct: 161 KIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 220
Query: 183 KKIINKVVEDTKLCSFPNINYNEIINATSYTIPDYFGVPIGTT 311
+ II K+ ED + S NI+Y + + + P G P T
Sbjct: 221 ELIIQKIQEDPQSGSCLNISYANVTGPVANSNPT--GSPYANT 261
Score = 56.6 bits (135), Expect = 9e-08
Identities = 40/116 (34%), Positives = 57/116 (49%)
Frame = +3
Query: 414 TPGTNSHFPVSRSLTTSFSQMDYIASDSSHGITRTLEVNETYIGAILGAKGRSIVELQEV 593
T TN +F + L S ++D S + + V E +GAILG G+++VE QE+
Sbjct: 378 TAATNGYFGAASPLAASAILGTEKSTDGSKDVVE-IAVPENLVGAILGKGGKTLVEYQEL 436
Query: 594 TDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKAYLLINDKIQLEQARRAMASQE 761
T I++SKK N++ VTITG A LI +I EQ RA Q+
Sbjct: 437 TGARIQISKKGEFVPGTRNRK-VTITGTPAATQAAQYLITQRITYEQGVRAANPQK 491
Score = 44.7 bits (104), Expect = 4e-04
Identities = 57/245 (23%), Positives = 97/245 (39%), Gaps = 4/245 (1%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS-PKSNNRQFLERYVLVMGDSHQCHEA 179
K++IP+ +AG +IGK G+TI ++K TGA I++S K ER L+ G +
Sbjct: 39 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAV 98
Query: 180 TKKIINKVVEDTKLCSFPNINYNE---IINATSYTIPDYFGVPIGTTPYNHTNSFENSTF 350
I K+ E + N+ E I+ + PD + +
Sbjct: 99 HGFIAEKIREMPQ-----NVAKTEPVSILQPQTTVNPDRIKQTLPS-------------- 139
Query: 351 SYSGNNFHMNSNQNNRNYGYYTPGTNSHFPVSRSLTTSFSQMDYIASDSSHGITRTLEVN 530
+P T P T+ +Q+ I +S+ G+
Sbjct: 140 ---------------------SPTTTKSSPSDPMTTSRANQVKIIVPNSTAGL------- 171
Query: 531 ETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKAYLLI 710
I+G G ++ + E + +++S+KP + +R+VT++G E KA LI
Sbjct: 172 ------IIGKGGATVKAIMEQSGAWVQLSQKP--DGINLQERVVTVSGEPEQNRKAVELI 223
Query: 711 NDKIQ 725
KIQ
Sbjct: 224 IQKIQ 228
Score = 33.5 bits (75), Expect = 0.82
Identities = 14/36 (38%), Positives = 25/36 (69%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPK 110
+I +P + G ++GK G+T+ + ++ TGA IQ+S K
Sbjct: 411 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 446
>sp|P51513|NOVA1_HUMAN RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1)
(Onconeural ventral antigen 1) (Paraneoplastic Ri
antigen) (Ventral neuron-specific protein 1)
Length = 510
Score = 70.1 bits (170), Expect = 8e-12
Identities = 39/103 (37%), Positives = 59/103 (57%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
KII+PNS+AGL+IGK G T+ + + +GA++Q+S K + ER V V G+ Q +A
Sbjct: 178 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 237
Query: 183 KKIINKVVEDTKLCSFPNINYNEIINATSYTIPDYFGVPIGTT 311
+ II K+ ED + S NI+Y + + + P G P T
Sbjct: 238 ELIIQKIQEDPQSGSCLNISYANVTGPVANSNPT--GSPYANT 278
Score = 56.6 bits (135), Expect = 9e-08
Identities = 40/116 (34%), Positives = 57/116 (49%)
Frame = +3
Query: 414 TPGTNSHFPVSRSLTTSFSQMDYIASDSSHGITRTLEVNETYIGAILGAKGRSIVELQEV 593
T TN +F + L S ++D S + + V E +GAILG G+++VE QE+
Sbjct: 395 TAATNGYFGAASPLAASAILGTEKSTDGSKDVVE-IAVPENLVGAILGKGGKTLVEYQEL 453
Query: 594 TDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKAYLLINDKIQLEQARRAMASQE 761
T I++SKK N++ VTITG A LI +I EQ RA Q+
Sbjct: 454 TGARIQISKKGEFVPGTRNRK-VTITGTPAATQAAQYLITQRITYEQGVRAANPQK 508
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/248 (23%), Positives = 100/248 (40%), Gaps = 7/248 (2%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQF----LERYVLVMGDSHQC 170
K++IP+ +AG +IGK G+TI ++K TGA I++S S ++ F ER L+ G
Sbjct: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKLSKSKDFYPGTTERVCLIQGTVEAL 112
Query: 171 HEATKKIINKVVEDTKLCSFPNINYNE---IINATSYTIPDYFGVPIGTTPYNHTNSFEN 341
+ I K+ E + N+ E I+ + PD + +
Sbjct: 113 NAVHGFIAEKIREMPQ-----NVAKTEPVSILQPQTTVNPDRIKQTLPS----------- 156
Query: 342 STFSYSGNNFHMNSNQNNRNYGYYTPGTNSHFPVSRSLTTSFSQMDYIASDSSHGITRTL 521
+P T P T+ +Q+ I +S+ G+
Sbjct: 157 ------------------------SPTTTKSSPSDPMTTSRANQVKIIVPNSTAGL---- 188
Query: 522 EVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKAY 701
I+G G ++ + E + +++S+KP + +R+VT++G E KA
Sbjct: 189 ---------IIGKGGATVKAVMEQSGAWVQLSQKP--DGINLQERVVTVSGEPEQNRKAV 237
Query: 702 LLINDKIQ 725
LI KIQ
Sbjct: 238 ELIIQKIQ 245
Score = 33.5 bits (75), Expect = 0.82
Identities = 14/36 (38%), Positives = 25/36 (69%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPK 110
+I +P + G ++GK G+T+ + ++ TGA IQ+S K
Sbjct: 428 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 463
>sp|P57722|PCBP3_MOUSE Poly(rC)-binding protein 3 (Alpha-CP3)
Length = 339
Score = 63.9 bits (154), Expect = 6e-10
Identities = 67/266 (25%), Positives = 113/266 (42%), Gaps = 23/266 (8%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS----PKSNNRQFLERYVLVMGDSHQC 170
++++P S G LIGK G I +I++STGA +QV+ P S ER V + G
Sbjct: 101 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNST-----ERAVTISGTPDAI 155
Query: 171 HEATKKIINKVVED----------TKLCSFPNINYNEIINATSYTIPDYFGVP-IGTTPY 317
+ K+I ++E K S P I +YTI + +P
Sbjct: 156 IQCVKQICVVMLESPPKGATIPYRPKPASTPVI----FAGGQAYTIQGQYAIPHPDQLTK 211
Query: 318 NHTNSFENSTF--------SYSGNNFHMNSNQNNRNYGYYTPGTNSHFPVSRSLTTSFSQ 473
H + + + F ++ G ++S++ +N + G ++ P S
Sbjct: 212 LHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPAS--------- 262
Query: 474 MDYIASDSSHGITRTLEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNK 653
T L + IG I+G +G I E+++++ IK++ TE S ++
Sbjct: 263 ------------THELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA-NATEGS---SE 306
Query: 654 RIVTITGLYENVSKAYLLINDKIQLE 731
R +TITG N+S A LIN ++ E
Sbjct: 307 RQITITGTPANISLAQYLINARLTSE 332
Score = 35.8 bits (81), Expect = 0.17
Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Frame = +3
Query: 474 MDYIASDSSHGITRTLEV--NETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKN 647
M+ S+ +T T+ + + +G+I+G KG ++ +++E + I +S+
Sbjct: 1 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP----- 55
Query: 648 NKRIVTITGLYENVSKAYLLINDKIQ 725
+RIVTITG + + KA+ +I K +
Sbjct: 56 -ERIVTITGPTDAIFKAFAMIAYKFE 80
Score = 34.3 bits (77), Expect = 0.48
Identities = 20/70 (28%), Positives = 35/70 (50%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
++++ G +IGK+GET+ +++ +GA I +S ER V + G + +A
Sbjct: 17 RLLMHGKEVGSIIGKKGETVKKMREESGARINIS----EGNCPERIVTITGPTDAIFKAF 72
Query: 183 KKIINKVVED 212
I K ED
Sbjct: 73 AMIAYKFEED 82
>sp|P57721|PCBP3_HUMAN Poly(rC)-binding protein 3 (Alpha-CP3)
Length = 339
Score = 63.9 bits (154), Expect = 6e-10
Identities = 67/266 (25%), Positives = 113/266 (42%), Gaps = 23/266 (8%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS----PKSNNRQFLERYVLVMGDSHQC 170
++++P S G LIGK G I +I++STGA +QV+ P S ER V + G
Sbjct: 101 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNST-----ERAVTISGTPDAI 155
Query: 171 HEATKKIINKVVED----------TKLCSFPNINYNEIINATSYTIPDYFGVP-IGTTPY 317
+ K+I ++E K S P I +YTI + +P
Sbjct: 156 IQCVKQICVVMLESPPKGATIPYRPKPASTPVI----FAGGQAYTIQGQYAIPHPDQLTK 211
Query: 318 NHTNSFENSTF--------SYSGNNFHMNSNQNNRNYGYYTPGTNSHFPVSRSLTTSFSQ 473
H + + + F ++ G ++S++ +N + G ++ P S
Sbjct: 212 LHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPAS--------- 262
Query: 474 MDYIASDSSHGITRTLEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNK 653
T L + IG I+G +G I E+++++ IK++ TE S ++
Sbjct: 263 ------------THELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA-NATEGS---SE 306
Query: 654 RIVTITGLYENVSKAYLLINDKIQLE 731
R +TITG N+S A LIN ++ E
Sbjct: 307 RQITITGTPANISLAQYLINARLTSE 332
Score = 35.8 bits (81), Expect = 0.17
Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Frame = +3
Query: 474 MDYIASDSSHGITRTLEV--NETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKN 647
M+ S+ +T T+ + + +G+I+G KG ++ +++E + I +S+
Sbjct: 1 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP----- 55
Query: 648 NKRIVTITGLYENVSKAYLLINDKIQ 725
+RIVTITG + + KA+ +I K +
Sbjct: 56 -ERIVTITGPTDAIFKAFAMIAYKFE 80
Score = 34.3 bits (77), Expect = 0.48
Identities = 20/70 (28%), Positives = 35/70 (50%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
++++ G +IGK+GET+ +++ +GA I +S ER V + G + +A
Sbjct: 17 RLLMHGKEVGSIIGKKGETVKKMREESGARINIS----EGNCPERIVTITGPTDAIFKAF 72
Query: 183 KKIINKVVED 212
I K ED
Sbjct: 73 AMIAYKFEED 82
>sp|Q61990|PCBP2_MOUSE Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous
nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP)
Length = 362
Score = 60.1 bits (144), Expect = 8e-09
Identities = 67/284 (23%), Positives = 115/284 (40%), Gaps = 41/284 (14%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS----PKSNNRQFLERYVLVMGDSHQC 170
++++P S G LIGK G I +I++STGA +QV+ P S ER + + G
Sbjct: 101 RLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST-----ERAITIAGIPQSI 155
Query: 171 HEATKKIINKVVED------------------------------TKLCSFPNINYNEIIN 260
E K+I ++E + SFP+ + +N
Sbjct: 156 IECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLN 215
Query: 261 AT-------SYTIPDYFGVPIGTTPYNHTNSFENSTFSYSGNNFHMNSNQNNRNYGYYTP 419
+YTI + +P H + + S F + N + +++
Sbjct: 216 PDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESS-------- 267
Query: 420 GTNSHFPVSRSLTTSFSQMDYIASDSSHGITRTLEVNETYIGAILGAKGRSIVELQEVTD 599
S + ++ +D A +SH +T + IG I+G +G I E+++++
Sbjct: 268 --------SPEVKGYWAGLDASAQTTSHELT----IPNDLIGCIIGRQGAKINEIRQMSG 315
Query: 600 TNIKVSKKPTENSDKNNKRIVTITGLYENVSKAYLLINDKIQLE 731
IK++ P E S R VTITG ++S A LIN ++ E
Sbjct: 316 AQIKIA-NPVEGS---TDRQVTITGSAASISLAQYLINVRLSSE 355
Score = 36.6 bits (83), Expect = 0.097
Identities = 20/73 (27%), Positives = 41/73 (56%)
Frame = +3
Query: 507 ITRTLEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNKRIVTITGLYEN 686
+T L ++ +G+I+G KG S+ +++E + I +S+ +RI+T+ G
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP------ERIITLAGPTNA 67
Query: 687 VSKAYLLINDKIQ 725
+ KA+ +I DK++
Sbjct: 68 IFKAFAMIIDKLE 80
Score = 36.2 bits (82), Expect = 0.13
Identities = 19/70 (27%), Positives = 39/70 (55%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
++++ G +IGK+GE++ +++ +GA I +S ER + + G ++ +A
Sbjct: 17 RLLMHGKEVGSIIGKKGESVKKMREESGARINIS----EGNCPERIITLAGPTNAIFKAF 72
Query: 183 KKIINKVVED 212
II+K+ ED
Sbjct: 73 AMIIDKLEED 82
>sp|P60335|PCBP1_MOUSE Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1)
sp|Q15365|PCBP1_HUMAN Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic
acid-binding protein SUB2.3)
sp|O19048|PCBP1_RABIT Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1)
Length = 356
Score = 58.9 bits (141), Expect = 2e-08
Identities = 71/272 (26%), Positives = 114/272 (41%), Gaps = 28/272 (10%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS----PKSNNRQFLERYVLVMGDSHQC 170
++++P + G LIGK G I +I++STGA +QV+ P S ER + + G
Sbjct: 101 RLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST-----ERAITIAGVPQSV 155
Query: 171 HEATKKIINKVVEDTKLCSFPNINYNEIINATSYTIPDYFGVPI--------GTTPYNHT 326
E K+I ++E ++ TIP Y +P G +
Sbjct: 156 TECVKQICLVMLE----------TLSQSPQGRVMTIP-YQPMPASSPVICAGGQDRCSDA 204
Query: 327 NSFENSTFSYSGNNFHMNSNQNNRNYG-------YYTPGTNSHFPVSRSLTTSFSQMD-- 479
+ ++T G S Q SHF + T F+ +D
Sbjct: 205 AGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHG-GTGFAGIDSS 263
Query: 480 ------YIAS-DSSHGITRTLEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENS 638
Y AS D+S T L + IG I+G +G +I E+++++ IK++ P E S
Sbjct: 264 SPEVKGYWASLDASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIA-NPVEGS 322
Query: 639 DKNNKRIVTITGLYENVSKAYLLINDKIQLEQ 734
+ R VTITG ++S A LIN ++ E+
Sbjct: 323 ---SGRQVTITGSAASISLAQYLINARLSSEK 351
Score = 40.0 bits (92), Expect = 0.009
Identities = 24/86 (27%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = +3
Query: 474 MDYIASDSSHGITRTLEV--NETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKN 647
MD ++S +T T+ + + +G+I+G KG S+ ++E + I +S+
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP----- 55
Query: 648 NKRIVTITGLYENVSKAYLLINDKIQ 725
+RI+T+TG + KA+ +I DK++
Sbjct: 56 -ERIITLTGPTNAIFKAFAMIIDKLE 80
Score = 37.0 bits (84), Expect = 0.074
Identities = 20/70 (28%), Positives = 39/70 (55%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
++++ G +IGK+GE++ I++ +GA I +S ER + + G ++ +A
Sbjct: 17 RLLMHGKEVGSIIGKKGESVKRIREESGARINIS----EGNCPERIITLTGPTNAIFKAF 72
Query: 183 KKIINKVVED 212
II+K+ ED
Sbjct: 73 AMIIDKLEED 82
>sp|Q15366|PCBP2_HUMAN Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2)
Length = 365
Score = 57.4 bits (137), Expect = 5e-08
Identities = 72/274 (26%), Positives = 115/274 (41%), Gaps = 31/274 (11%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS----PKSNNRQFLERYVLVMGDSHQC 170
++++P S G LIGK G I +I++STGA +QV+ P S ER + + G
Sbjct: 101 RLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNST-----ERAITIAGIPQSI 155
Query: 171 HEATKKIINKVVEDTKLCSFPNINYNEIINATSYTIPDYFGVPIGTTPYNHTNSFENSTF 350
E K+I ++E L P + P F G T S ++++F
Sbjct: 156 IECVKQICVVMLET--LSQSPPKGVTIPYRPKPSSSPVIFA---GGQDRYSTGS-DSASF 209
Query: 351 SYSGNNFHMNSNQNNRNYGYYT------------------PGTNSHFPVSRSLTTSFSQM 476
++ + +N + YT SHFP++ T FS +
Sbjct: 210 PHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHG-NTGFSGI 268
Query: 477 D--------YIASDSSHGIT-RTLEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPT 629
+ Y D+S T L + IG I+G +G I E+++++ IK++ P
Sbjct: 269 ESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIA-NPV 327
Query: 630 ENSDKNNKRIVTITGLYENVSKAYLLINDKIQLE 731
E S R VTITG ++S A LIN ++ E
Sbjct: 328 EGS---TDRQVTITGSAASISLAQYLINVRLSSE 358
Score = 36.6 bits (83), Expect = 0.097
Identities = 20/73 (27%), Positives = 41/73 (56%)
Frame = +3
Query: 507 ITRTLEVNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNKRIVTITGLYEN 686
+T L ++ +G+I+G KG S+ +++E + I +S+ +RI+T+ G
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP------ERIITLAGPTNA 67
Query: 687 VSKAYLLINDKIQ 725
+ KA+ +I DK++
Sbjct: 68 IFKAFAMIIDKLE 80
Score = 36.2 bits (82), Expect = 0.13
Identities = 19/70 (27%), Positives = 39/70 (55%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
++++ G +IGK+GE++ +++ +GA I +S ER + + G ++ +A
Sbjct: 17 RLLMHGKEVGSIIGKKGESVKKMREESGARINIS----EGNCPERIITLAGPTNAIFKAF 72
Query: 183 KKIINKVVED 212
II+K+ ED
Sbjct: 73 AMIIDKLEED 82
>sp|P57723|PCBP4_HUMAN Poly(rC)-binding protein 4 (Alpha-CP4)
Length = 403
Score = 51.6 bits (122), Expect = 3e-06
Identities = 60/242 (24%), Positives = 98/242 (40%), Gaps = 6/242 (2%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVS----PKSNNRQFLERYVLVMGDSHQC 170
+++IP S G LIGK G I +I+++TGA +QV+ P S ER V V G
Sbjct: 105 RLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNST-----ERAVTVSGVPDAI 159
Query: 171 HEATKKIINKVVEDTKLCSFPNINYNEIINATSYTIPDYFGVPIGTTPYNHTNSFENSTF 350
++I ++E TIP + + +GT + N F
Sbjct: 160 ILCVRQICAVILESP---------------PKGATIPYHPSLSLGTVLLS-----ANQGF 199
Query: 351 SYSGNNFHMNSNQNNRNYGYYTPGTNSHFPVSRSLTTSFSQMDYIASDSSHGITRTLE-- 524
S G YG TP + S F+ + T + E
Sbjct: 200 SVQG------------QYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFL 247
Query: 525 VNETYIGAILGAKGRSIVELQEVTDTNIKVSKKPTENSDKNNKRIVTITGLYENVSKAYL 704
V IG ++G +G I E+++++ +IK+ + ++ +R VTITG +++ A
Sbjct: 248 VPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQ----AEGAGERHVTITGSPVSIALAQY 303
Query: 705 LI 710
LI
Sbjct: 304 LI 305
Score = 34.7 bits (78), Expect = 0.37
Identities = 23/77 (29%), Positives = 38/77 (49%)
Frame = +3
Query: 3 KIIIPNSSAGLLIGKEGETINDIKKSTGAFIQVSPKSNNRQFLERYVLVMGDSHQCHEAT 182
++++ G +IGK+GET+ I++ + A I +S S ER + G + A
Sbjct: 21 RMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS----CPERITTITGSTAAVFHAV 76
Query: 183 KKIINKVVEDTKLCSFP 233
I K+ ED LC+ P
Sbjct: 77 SMIAFKLDED--LCAAP 91
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,972,963
Number of Sequences: 369166
Number of extensions: 1887888
Number of successful extensions: 6943
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5595
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6352
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)