Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_C24
(554 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UGI6|KCNN3_HUMAN Small conductance calcium-activated p... 134 2e-31
sp|P58392|KCNN3_PIG Small conductance calcium-activated pot... 134 2e-31
sp|P70605|KCNN3_RAT Small conductance calcium-activated pot... 133 3e-31
sp|P58391|KCNN3_MOUSE Small conductance calcium-activated p... 131 1e-30
sp|P58390|KCNN2_MOUSE Small conductance calcium-activated p... 129 5e-30
sp|P70604|KCNN2_RAT Small conductance calcium-activated pot... 129 5e-30
sp|Q9H2S1|KCNN2_HUMAN Small conductance calcium-activated p... 129 5e-30
sp|Q9EQR3|KCNN1_MOUSE Small conductance calcium-activated p... 121 1e-27
sp|P70606|KCNN1_RAT Small conductance calcium-activated pot... 121 1e-27
sp|Q92952|KCNN1_HUMAN Small conductance calcium-activated p... 121 1e-27
>sp|Q9UGI6|KCNN3_HUMAN Small conductance calcium-activated potassium channel protein 3 (SK3)
(SKCa3)
Length = 736
Score = 134 bits (336), Expect = 2e-31
Identities = 67/176 (38%), Positives = 114/176 (64%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 502 AMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 561
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLLYNIREVRLIRL 366
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L I ++R +++
Sbjct: 562 NFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKM 621
Query: 367 ARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKLNYK*LRSSF 534
+R+LSD + +++++S+ Q L+ +N +E + S+ KL + L +SF
Sbjct: 622 EQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEH--LTASF 675
>sp|P58392|KCNN3_PIG Small conductance calcium-activated potassium channel protein 3 (SK3)
Length = 724
Score = 134 bits (336), Expect = 2e-31
Identities = 67/176 (38%), Positives = 114/176 (64%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 490 AMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 549
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLLYNIREVRLIRL 366
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L I ++R +++
Sbjct: 550 NFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKM 609
Query: 367 ARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKLNYK*LRSSF 534
+R+LSD + +++++S+ Q L+ +N +E + S+ KL + L +SF
Sbjct: 610 EQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEH--LTASF 663
>sp|P70605|KCNN3_RAT Small conductance calcium-activated potassium channel protein 3 (SK3)
Length = 732
Score = 133 bits (334), Expect = 3e-31
Identities = 67/176 (38%), Positives = 114/176 (64%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 498 AMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 557
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLLYNIREVRLIRL 366
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L I ++R +++
Sbjct: 558 NFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRGVKM 617
Query: 367 ARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKLNYK*LRSSF 534
+R+LSD + +++++S+ Q L+ +N +E + S+ KL + L +SF
Sbjct: 618 EQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEH--LTASF 671
>sp|P58391|KCNN3_MOUSE Small conductance calcium-activated potassium channel protein 3 (SK3)
Length = 731
Score = 131 bits (329), Expect = 1e-30
Identities = 66/176 (37%), Positives = 113/176 (64%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 497 AMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 556
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLLYNIREVRLIRL 366
NF+ D+QL + +K+A+ N+++ +W +Y+ D V ++RK L I ++R +++
Sbjct: 557 NFMMDTQLTKRIKNAATNVLRETWLVYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRGVKM 616
Query: 367 ARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKLNYK*LRSSF 534
+R+LSD + +++++S+ Q L+ +N +E + S+ KL + L +SF
Sbjct: 617 EQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEH--LTASF 670
>sp|P58390|KCNN2_MOUSE Small conductance calcium-activated potassium channel protein 2
(SK2)
Length = 574
Score = 129 bits (324), Expect = 5e-30
Identities = 60/167 (35%), Positives = 110/167 (65%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 343 AMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 402
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLLYNIREVRLIRL 366
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L I ++R +++
Sbjct: 403 NFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKM 462
Query: 367 ARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKL 507
+R+L+D + +++++++ Q ++ ++N+ E + ++ KL
Sbjct: 463 EQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKL 509
>sp|P70604|KCNN2_RAT Small conductance calcium-activated potassium channel protein 2
(SK2)
Length = 580
Score = 129 bits (324), Expect = 5e-30
Identities = 60/167 (35%), Positives = 110/167 (65%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 349 AMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 408
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLLYNIREVRLIRL 366
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L I ++R +++
Sbjct: 409 NFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKM 468
Query: 367 ARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKL 507
+R+L+D + +++++++ Q ++ ++N+ E + ++ KL
Sbjct: 469 EQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKL 515
>sp|Q9H2S1|KCNN2_HUMAN Small conductance calcium-activated potassium channel protein 2
(SK2)
Length = 579
Score = 129 bits (324), Expect = 5e-30
Identities = 60/167 (35%), Positives = 110/167 (65%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 348 AMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 407
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLLYNIREVRLIRL 366
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L I ++R +++
Sbjct: 408 NFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKM 467
Query: 367 ARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKL 507
+R+L+D + +++++++ Q ++ ++N+ E + ++ KL
Sbjct: 468 EQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKL 514
>sp|Q9EQR3|KCNN1_MOUSE Small conductance calcium-activated potassium channel protein 1
(SK1)
Length = 580
Score = 121 bits (304), Expect = 1e-27
Identities = 58/171 (33%), Positives = 112/171 (65%), Gaps = 3/171 (1%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 360 AMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 419
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLL---YNIREVRL 357
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L + +++R
Sbjct: 420 NFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQGRVRKHQRKFLQAIHQAQKLRS 479
Query: 358 IRLARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKLN 510
+++ + +++D + ++ E+++AQ + ++ + + ++E L ++ +L+
Sbjct: 480 VKIEQGKVNDQANTLAELAKAQSIAYEVVSELQAQQEELEARLAALESRLD 530
>sp|P70606|KCNN1_RAT Small conductance calcium-activated potassium channel protein 1
(SK1)
Length = 536
Score = 121 bits (304), Expect = 1e-27
Identities = 57/171 (33%), Positives = 112/171 (65%), Gaps = 3/171 (1%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 316 AMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 375
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLL---YNIREVRL 357
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L + +++R
Sbjct: 376 NFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQSRVRKHQRKFLQAIHQAQKLRT 435
Query: 358 IRLARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKLN 510
+++ + +++D + ++ ++++AQ + ++ + + ++E L ++ +L+
Sbjct: 436 VKIEQGKVNDQANTLADLAKAQSIAYEVVSELQAQQEELEARLAALESRLD 486
>sp|Q92952|KCNN1_HUMAN Small conductance calcium-activated potassium channel protein 1
(SK1)
Length = 561
Score = 121 bits (303), Expect = 1e-27
Identities = 58/171 (33%), Positives = 111/171 (64%), Gaps = 3/171 (1%)
Frame = +1
Query: 7 SMWLTAITFLSIGYGDIIPTTHCGRAVXXXXXXXXXXCTALVVAIVSSKLELTQSEKYLH 186
+MWL +ITFLSIGYGD++P T+CG+ V CTALVVA+V+ KLELT++EK++H
Sbjct: 338 AMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVH 397
Query: 187 NFVQDSQLNQHLKHASANIVKYSWRLYRLKNKKHSGDTKSVIYNKRKLL---YNIREVRL 357
NF+ D+QL + +K+A+AN+++ +W +Y+ D V ++RK L + +++R
Sbjct: 398 NFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRS 457
Query: 358 IRLARRQLSDSSISILEVSRAQINSRVLLDNMNQEIGQIETMLQSICEKLN 510
+++ + +L+D + ++ ++++ Q L+ ++ + ++E L ++ +L+
Sbjct: 458 VKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLD 508
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,729,286
Number of Sequences: 369166
Number of extensions: 1061306
Number of successful extensions: 3044
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2935
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3040
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3931403200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)