Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_C17
(614 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13642|FHL1_HUMAN Four and a half LIM domains protein 1 ... 123 4e-28
sp|P97447|FHL1_MOUSE Four and a half LIM domains protein 1 ... 122 9e-28
sp|O70433|FHL2_MOUSE Four and a half LIM domains protein 2 ... 118 1e-26
sp|O35115|FHL2_RAT Four and a half LIM domains protein 2 (F... 117 3e-26
sp|Q14192|FHL2_HUMAN Four and a half LIM domains protein 2 ... 117 3e-26
sp|Q9WTX7|FHL5_MOUSE Four and a half LIM domains protein 5 ... 115 1e-25
sp|Q6AXT1|FHL5_RAT Four and a half LIM domains protein 5 (F... 114 2e-25
sp|Q5TD97|FHL5_HUMAN Four and a half LIM domains protein 5 ... 114 3e-25
sp|Q9R059|FHL3_MOUSE Four and a half LIM domains protein 3 ... 108 1e-23
sp|Q13643|FHL3_HUMAN Four and a half LIM domains protein 3 ... 107 2e-23
>sp|Q13642|FHL1_HUMAN Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle
LIM-protein 1) (SLIM 1) (SLIM)
Length = 323
Score = 123 bits (308), Expect = 4e-28
Identities = 55/190 (28%), Positives = 87/190 (45%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C + I K ++ WH+ CF C+ C + N F D N+ILC KC +
Sbjct: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKD-NKILCNKCTTREDS 98
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C + D+ + +WH+ CF C NC+ ++ SF+ YC C+ F
Sbjct: 99 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
+ C KC + I I +++ H++CF+C C L +RF + +C +CY VA
Sbjct: 159 AKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVA 218
Query: 568 RHAQDAKNTL 597
+ KN +
Sbjct: 219 KKCAGCKNPI 228
Score = 71.6 bits (174), Expect = 1e-12
Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 2/158 (1%)
Frame = +1
Query: 106 FICSVCSENMENVLFSLNDLNEILCYKCYDEKFGIICSTCQDLVKLSDEKFKLGNLIWHR 285
F C C + ++ + D + C KC+D+ C C+ + ++ N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHC-CLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHD 63
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKI--WKNLIRFRELNLH 459
CF+C C L +F DN C C + C C + I + ++ H
Sbjct: 64 TCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH 123
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARH 573
+CF C+ C + FF K E +C C+ A+H
Sbjct: 124 KDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH 161
>sp|P97447|FHL1_MOUSE Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle
LIM-protein 1) (SLIM 1) (SLIM) (KyoT) (RBP-associated
molecule 14-1) (RAM14-1)
Length = 280
Score = 122 bits (305), Expect = 9e-28
Identities = 55/190 (28%), Positives = 87/190 (45%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C + I K ++ WH+NCF C+ C + + F D +ILC KC +
Sbjct: 40 CVDCRKPISADAKEVHYKNRYWHDNCFRCAKCLHPLASETFVSKD-GKILCNKCATREDS 98
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C + D+ + +WH+ CF C NC+ ++ SF+ YC C+ F
Sbjct: 99 PRCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
+ C KC + I I +++ H+ECF+C C L +RF + +C +CY VA
Sbjct: 159 AKHCVKCNKAITSGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVA 218
Query: 568 RHAQDAKNTL 597
+ KN +
Sbjct: 219 KKCAGCKNPI 228
Score = 100 bits (250), Expect = 2e-21
Identities = 47/179 (26%), Positives = 83/179 (46%), Gaps = 5/179 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C GC ++I +++ ++G +WH++CF CS C + + F + C C++ KF
Sbjct: 101 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKG-EDFYCVTCHETKFA 159
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C + ++ + WH +CF C C L F ++ YC +CY
Sbjct: 160 KHCVKCNKAITSGGITYQ--DQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217
Query: 388 TEICDKCQEKIW-----KNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
+ C C+ I +++ + + H CF C C + L +KRF + NE ++C +C
Sbjct: 218 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHNEQVYCPDC 276
Score = 69.3 bits (168), Expect = 7e-12
Identities = 38/158 (24%), Positives = 61/158 (38%), Gaps = 2/158 (1%)
Frame = +1
Query: 106 FICSVCSENMENVLFSLNDLNEILCYKCYDEKFGIICSTCQDLVKLSDEKFKLGNLIWHR 285
F C C + ++ + D C KC+D+ C C+ + ++ N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKD-GRHCCLKCFDKFCANTCVDCRKPISADAKEVHYKNRYWHD 63
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKI--WKNLIRFRELNLH 459
CF+C C L +F D C C + C C + I + ++ H
Sbjct: 64 NCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRCKGCFKAIVAGDQNVEYKGTVWH 123
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARH 573
+CF C+ C + FF K E +C C+ A+H
Sbjct: 124 KDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKH 161
Score = 55.8 bits (133), Expect = 8e-08
Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C CN++I +++ WH CF+C CS+ + F+ + ++ C CY
Sbjct: 162 CVKCNKAIT--SGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVE-DQYYCVDCYKNFVA 218
Query: 208 IICSTCQDLVKLSDEKFKLGNLI-------WHRKCFQCQNCRDILNPNSFWLHDNLSYCK 366
C+ C++ + F G+ + WH CF C+ C L F H+ YC
Sbjct: 219 KKCAGCKNPIT----GFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHNEQVYCP 274
Query: 367 NCYGEL 384
+C +L
Sbjct: 275 DCAKKL 280
>sp|O70433|FHL2_MOUSE Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle
LIM-protein 3) (SLIM 3)
Length = 279
Score = 118 bits (296), Expect = 1e-26
Identities = 54/193 (27%), Positives = 90/193 (46%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C I K S++ WHE CF CS C ++ + F+ + ++LC CY ++
Sbjct: 40 CEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKE-EQLLCTDCYSNEYS 98
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C+ + K + WH CF CQ C+ + SF +N ++C CY + +
Sbjct: 99 SKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQY 158
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
C +C++ I + +RE H ECF+C C L+ +RF ++E +C C+ + A
Sbjct: 159 ALQCVQCKKPITTGGVTYREQPWHKECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYA 218
Query: 568 RHAQDAKNTLQVL 606
+ N + L
Sbjct: 219 KKCAGCTNPISGL 231
Score = 102 bits (254), Expect = 8e-22
Identities = 48/178 (26%), Positives = 80/178 (44%), Gaps = 4/178 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C ++I + ++G WHE CF C C + + F + N+ C CY++++
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKE-NQNFCVPCYEKQYA 159
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
+ C C+ + ++ WH++CF C C+ L+ F D YC C+ +L+
Sbjct: 160 LQCVQCKKPITTGGVTYR--EQPWHKECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLY 217
Query: 388 TEICDKCQEKI----WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
+ C C I I F E H++CF C C L L + F + + I C +C
Sbjct: 218 AKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 66.6 bits (161), Expect = 5e-11
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Frame = +1
Query: 292 FQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIWKNL--IRFRELNLHSE 465
F C +C + L + L + +C C+ EL+ C++C I + + +++ + H
Sbjct: 5 FDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEG 64
Query: 466 CFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF C+ C L DK F K E + C +CY+ + Q+ K T+
Sbjct: 65 CFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTI 108
>sp|O35115|FHL2_RAT Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle
LIM-protein 3) (SLIM 3) (LIM-domain protein DRAL)
Length = 279
Score = 117 bits (292), Expect = 3e-26
Identities = 53/193 (27%), Positives = 90/193 (46%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C I K S++ WHE CF CS C ++ + F+ + ++LC CY ++
Sbjct: 40 CEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKE-EQLLCTDCYSNEYS 98
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C+ + K + WH CF CQ C+ + SF +N ++C CY + +
Sbjct: 99 SKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQY 158
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
C +C++ I + +R+ H ECF+C C L+ +RF ++E +C C+ + A
Sbjct: 159 ALQCVQCKKPITTGGVTYRDQPWHRECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYA 218
Query: 568 RHAQDAKNTLQVL 606
+ N + L
Sbjct: 219 KKCAGCTNPISGL 231
Score = 103 bits (258), Expect = 3e-22
Identities = 49/178 (27%), Positives = 81/178 (45%), Gaps = 4/178 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C ++I + ++G WHE CF C C + + F + N+ C CY++++
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKE-NQNFCVPCYEKQYA 159
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
+ C C+ + ++ + WHR+CF C C+ L+ F D YC C+ +L+
Sbjct: 160 LQCVQCKKPITTGGVTYR--DQPWHRECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLY 217
Query: 388 TEICDKCQEKI----WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
+ C C I I F E H++CF C C L L + F + + I C +C
Sbjct: 218 AKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 66.6 bits (161), Expect = 5e-11
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Frame = +1
Query: 292 FQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIWKNL--IRFRELNLHSE 465
F C +C + L + L + +C C+ EL+ C++C I + + +++ + H
Sbjct: 5 FDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEG 64
Query: 466 CFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF C+ C L DK F K E + C +CY+ + Q+ K T+
Sbjct: 65 CFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTI 108
>sp|Q14192|FHL2_HUMAN Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle
LIM-protein 3) (SLIM 3) (LIM-domain protein DRAL)
Length = 279
Score = 117 bits (292), Expect = 3e-26
Identities = 54/193 (27%), Positives = 90/193 (46%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C + I K S++ WHE CF CS C ++ + F+ + +++LC CY ++
Sbjct: 40 CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKE-DQLLCTDCYSNEYS 98
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C+ + K + WH CF C C+ + SF DN ++C CY +
Sbjct: 99 SKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQH 158
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
C +C+ I + +RE H ECF+C C L+ +RF +++ +C NC+ + A
Sbjct: 159 AMQCVQCKMPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYA 218
Query: 568 RHAQDAKNTLQVL 606
+ N + L
Sbjct: 219 KKCAGCTNPISGL 231
Score = 107 bits (267), Expect = 2e-23
Identities = 52/178 (29%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C ++I + ++G WHE CFIC C + + F D N+ C CY+++
Sbjct: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKD-NQNFCVPCYEKQHA 159
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
+ C C+ + ++ WH++CF C CR L+ F D+ +YC NC+ +L+
Sbjct: 160 MQCVQCKMPITTGGVTYR--EQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
Query: 388 TEICDKCQEKI----WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
+ C C I I F E H++CF C C L L + F + + I C +C
Sbjct: 218 AKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
Score = 67.0 bits (162), Expect = 4e-11
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Frame = +1
Query: 292 FQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIWKNL--IRFRELNLHSE 465
F C +C + L + L + YC C+ LF C++C + I + + +++ + H
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 466 CFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF C+ C L DK F K + + C +CY+ + Q+ K T+
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTI 108
>sp|Q9WTX7|FHL5_MOUSE Four and a half LIM domains protein 5 (FHL-5) (Activator of
cAMP-responsive element modulator in testis) (Activator
of CREM in testis)
Length = 284
Score = 115 bits (287), Expect = 1e-25
Identities = 53/181 (29%), Positives = 85/181 (46%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C E I+ K ++ WHE CF C+ C ++ F D + +LC CY +
Sbjct: 41 CEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKD-DRLLCTDCYSNECS 99
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C+ + K + WH CF C++CR + ++ +YC C+ + F
Sbjct: 100 SKCFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEF 159
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
C+ C++ I I FR+ H ECF+C+ C L ++ F K++ FC +CYN A
Sbjct: 160 AHYCNFCKKVITSGGITFRDQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHLYA 219
Query: 568 R 570
+
Sbjct: 220 K 220
Score = 106 bits (265), Expect = 4e-23
Identities = 54/179 (30%), Positives = 83/179 (46%), Gaps = 5/179 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENM-ENVLFSLNDLNEILCYKCYDEKF 204
C C +I + F+G WHE CF+C C + + L S N C C++++F
Sbjct: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGN--YCVPCFEKEF 159
Query: 205 GIICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGEL 384
C+ C+ ++ F+ + IWH++CF C CR L +F D+ +C +CY L
Sbjct: 160 AHYCNFCKKVITSGGITFR--DQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHL 217
Query: 385 FTEICDKCQEKI----WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
+ + C C + I I F++ HSECF C C + L + F N I C C
Sbjct: 218 YAKKCAACTKPITGLRGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTHNMEILCRKC 276
Score = 79.0 bits (193), Expect = 9e-15
Identities = 41/166 (24%), Positives = 65/166 (39%), Gaps = 2/166 (1%)
Frame = +1
Query: 106 FICSVCSENMENVLFSLNDLNEILCYKCYDEKFGIICSTCQDLVKLSDEKFKLGNLIWHR 285
F C C+ ++ + L D N + C CYD F C C++ ++ + N WH
Sbjct: 6 FDCQYCTSSLIGKKYVLKDDN-LYCISCYDRIFSNYCEQCKEPIESDSKDLCYKNRHWHE 64
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIW--KNLIRFRELNLH 459
CF+C C L F D+ C +CY + C C+ I + F+ H
Sbjct: 65 GCFRCNKCHHSLVEKPFVAKDDRLLCTDCYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF+C C + K K +C C+ + A + K +
Sbjct: 125 ETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI 170
Score = 32.0 bits (71), Expect = 1.3
Identities = 11/47 (23%), Positives = 24/47 (51%)
Frame = +1
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTLQ 600
S F C C L K++ K++ ++C +CY+ + + + K ++
Sbjct: 3 SSQFDCQYCTSSLIGKKYVLKDDNLYCISCYDRIFSNYCEQCKEPIE 49
>sp|Q6AXT1|FHL5_RAT Four and a half LIM domains protein 5 (FHL-5)
Length = 284
Score = 114 bits (286), Expect = 2e-25
Identities = 53/181 (29%), Positives = 84/181 (46%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C E I+ K ++ WHE CF C+ C ++ F D +LC CY +
Sbjct: 41 CEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKD-ERLLCTDCYSNECS 99
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C+ + K + WH CF C++CR + ++ +YC C+ + F
Sbjct: 100 SKCFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEF 159
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
C+ C++ I I FR+ H ECF+C+ C L ++ F K++ FC +CYN A
Sbjct: 160 AHYCNFCKKVITSGGITFRDQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHLYA 219
Query: 568 R 570
+
Sbjct: 220 K 220
Score = 107 bits (267), Expect = 2e-23
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 5/179 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENM-ENVLFSLNDLNEILCYKCYDEKF 204
C C +I + F+G WHE CF+C C + + L S N C C++++F
Sbjct: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGN--YCVPCFEKEF 159
Query: 205 GIICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGEL 384
C+ C+ ++ F+ + IWH++CF C CR L +F D+ +C +CY L
Sbjct: 160 AHYCNFCKKVITSGGITFR--DQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHL 217
Query: 385 FTEICDKCQEKI----WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
+ + C C + I I F++ HSECF C C + L + F +N I C C
Sbjct: 218 YAKKCAACTKPITGLRGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTQNMEILCRKC 276
Score = 78.2 bits (191), Expect = 2e-14
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = +1
Query: 106 FICSVCSENMENVLFSLNDLNEILCYKCYDEKFGIICSTCQDLVKLSDEKFKLGNLIWHR 285
F C C+ ++ + L D N + C CYD F C C++ ++ + N WH
Sbjct: 6 FDCQYCTASLLGKKYVLKDDN-LYCISCYDRIFSNYCEQCKEPIESDSKDLCYKNRHWHE 64
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIW--KNLIRFRELNLH 459
CF+C C L F D C +CY + C C+ I + F+ H
Sbjct: 65 GCFRCNKCHHSLVEKPFVAKDERLLCTDCYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF+C C + K K +C C+ + A + K +
Sbjct: 125 ETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI 170
Score = 32.0 bits (71), Expect = 1.3
Identities = 10/44 (22%), Positives = 23/44 (52%)
Frame = +1
Query: 469 FICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTLQ 600
F C C L K++ K++ ++C +CY+ + + + K ++
Sbjct: 6 FDCQYCTASLLGKKYVLKDDNLYCISCYDRIFSNYCEQCKEPIE 49
>sp|Q5TD97|FHL5_HUMAN Four and a half LIM domains protein 5 (FHL-5) (Activator of
cAMP-responsive element modulator in testis) (Activator
of CREM in testis)
Length = 284
Score = 114 bits (284), Expect = 3e-25
Identities = 50/176 (28%), Positives = 85/176 (48%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C + I+ K ++ WHE CF C+ C+ ++ F+ D +LC +CY +
Sbjct: 41 CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKD-ERLLCTECYSNECS 99
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C C+ + K + WH CF C+NCR + ++ +YC C+ + F
Sbjct: 100 SKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEF 159
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYN 555
C+ C++ I I F + H ECF+C+ C L +++F +++ FC +CYN
Sbjct: 160 AHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCVDCYN 215
Score = 109 bits (272), Expect = 6e-24
Identities = 55/179 (30%), Positives = 83/179 (46%), Gaps = 5/179 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENM-ENVLFSLNDLNEILCYKCYDEKF 204
C C +I + F+G WHE CF+C C + + L S N C C++++F
Sbjct: 102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGN--YCVPCFEKEF 159
Query: 205 GIICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGEL 384
C+ C+ ++ F + +WH++CF C CR L F D+ +C +CY L
Sbjct: 160 AHYCNFCKKVITSGGITFC--DQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCVDCYNHL 217
Query: 385 FTEICDKCQEKI----WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
+ C C + I I F++ HSECF C C + L K F +N+ IFC C
Sbjct: 218 YANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
Score = 72.8 bits (177), Expect = 7e-13
Identities = 39/166 (23%), Positives = 61/166 (36%), Gaps = 2/166 (1%)
Frame = +1
Query: 106 FICSVCSENMENVLFSLNDLNEILCYKCYDEKFGIICSTCQDLVKLSDEKFKLGNLIWHR 285
F C C+ ++ + L D + C CYD F C C+ ++ + + WH
Sbjct: 6 FYCQYCTASLLGKKYVLKD-DSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIW--KNLIRFRELNLH 459
CF+C C L F D C CY + C C+ I + F+ H
Sbjct: 65 GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF+C C + K K +C C+ + A + K +
Sbjct: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI 170
Score = 56.2 bits (134), Expect = 6e-08
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
CN C + I +F +WH+ CF+CS C +++ F D + C CY+ +
Sbjct: 163 CNFCKKVIT--SGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRD-DYPFCVDCYNHLYA 219
Query: 208 IICSTCQDLVK-LSDEKFK-LGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGE 381
C C + L+ KF + WH +CF C C L F + +C+ C
Sbjct: 220 NKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSG 279
Query: 382 LFTEI 396
+ T+I
Sbjct: 280 MDTDI 284
Score = 31.6 bits (70), Expect = 1.7
Identities = 10/44 (22%), Positives = 22/44 (50%)
Frame = +1
Query: 469 FICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTLQ 600
F C C L K++ K++ +C CY+ + + ++ K ++
Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIE 49
>sp|Q9R059|FHL3_MOUSE Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle
LIM-protein 2) (SLIM 2)
Length = 289
Score = 108 bits (269), Expect = 1e-23
Identities = 51/177 (28%), Positives = 78/177 (44%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C + I + +E +HE CF C C ++ + F+ D +E+LC +CY F
Sbjct: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQD-SELLCNECYCTAFS 98
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
CS C + V K + G WH CF C C L SF YC CY F
Sbjct: 99 SQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLASRSFVPDKGAHYCVPCYENKF 158
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNE 558
C +C + + + + +R+ H EC +C C L + F +++ +C C+ E
Sbjct: 159 APRCARCSKTLTQGGVTYRDQPWHRECLVCTGCKTPLAGQHFTSRDDDPYCVACFGE 215
Score = 99.8 bits (247), Expect = 5e-21
Identities = 50/187 (26%), Positives = 77/187 (41%), Gaps = 13/187 (6%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C+ C E++ + + G WHE+CF+CS C + + + F + D C CY+ KF
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLASRSF-VPDKGAHYCVPCYENKFA 159
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C+ C + ++ + WHR+C C C+ L F D+ YC C+GELF
Sbjct: 160 PRCARCSKTLTQGGVTYR--DQPWHRECLVCTGCKTPLAGQHFTSRDDDPYCVACFGELF 217
Query: 388 TEICDKCQEKI-------------WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNE 528
C C I + F + + H CF C C L + F +
Sbjct: 218 APKCSSCNRPITGGSGGAEGAGLGGGKYVSFEDRHWHHSCFSCARCSTSLVGQGFVPDGD 277
Query: 529 LIFCDNC 549
+ C C
Sbjct: 278 QVLCQGC 284
Score = 78.6 bits (192), Expect = 1e-14
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = +1
Query: 106 FICSVCSENMENVLFSLNDLNEILCYKCYDEKFGIICSTCQDLVKLSDEKFKLGNLIWHR 285
F C+ C+E++ + D C CYD F C+ CQ L+ + + +H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPY-CVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHE 63
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIW--KNLIRFRELNLH 459
CF+C C+ L F D+ C CY F+ C C E + + + H
Sbjct: 64 GCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQCSACGETVMPGSRKLEYGGQTWH 123
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF+C+ C+ L + F +C CY A TL
Sbjct: 124 EHCFLCSGCEQPLASRSFVPDKGAHYCVPCYENKFAPRCARCSKTL 169
Score = 55.1 bits (131), Expect = 1e-07
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 2/91 (2%)
Frame = +1
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIWKNL--IRFRELNLH 459
+ F C C + L + D+ YC CY F C +CQ+ I + + + + + H
Sbjct: 3 EAFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCY 552
CF C C L D+ F ++ + C+ CY
Sbjct: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNECY 93
>sp|Q13643|FHL3_HUMAN Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle
LIM-protein 2) (SLIM 2)
Length = 280
Score = 107 bits (268), Expect = 2e-23
Identities = 53/190 (27%), Positives = 81/190 (42%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C C + I + +E +HE CF C C ++ + F+ D +E+LC CY F
Sbjct: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTRQD-SELLCNDCYCSAFS 98
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
CS C + V K + G WH CF C C L F YC CY F
Sbjct: 99 SQCSACGETVMPGSRKLEYGGQTWHEHCFLCIGCEQPLGSRPFVPDKGAHYCVPCYENNF 158
Query: 388 TEICDKCQEKIWKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVA 567
C +C + + + + +R+L H +C +C C L ++F ++E +C C+ E A
Sbjct: 159 APRCARCTKTLTQGGLTYRDLPWHPKCLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFA 218
Query: 568 RHAQDAKNTL 597
K +
Sbjct: 219 PKCSSCKRPI 228
Score = 99.4 bits (246), Expect = 7e-21
Identities = 49/178 (27%), Positives = 76/178 (42%), Gaps = 4/178 (2%)
Frame = +1
Query: 28 CNGCNESIDLHEKHASFEGFIWHENCFICSVCSENMENVLFSLNDLNEILCYKCYDEKFG 207
C+ C E++ + + G WHE+CF+C C + + + F + D C CY+ F
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCIGCEQPLGSRPF-VPDKGAHYCVPCYENNFA 159
Query: 208 IICSTCQDLVKLSDEKFKLGNLIWHRKCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELF 387
C+ C + ++ +L WH KC C C+ L F D YC C+GELF
Sbjct: 160 PRCARCTKTLTQGGLTYR--DLPWHPKCLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
Query: 388 TEICDKCQEKI----WKNLIRFRELNLHSECFICNVCDLGLTDKRFFYKNELIFCDNC 549
C C+ I + F + + H CF C+ C L + F + + C C
Sbjct: 218 APKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFTCDRCSNSLVGQGFVPDGDQVLCQGC 275
Score = 78.2 bits (191), Expect = 2e-14
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 2/166 (1%)
Frame = +1
Query: 106 FICSVCSENMENVLFSLNDLNEILCYKCYDEKFGIICSTCQDLVKLSDEKFKLGNLIWHR 285
F C+ C+E++ + D C CYD F C+ CQ L+ + + +H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPY-CVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHE 63
Query: 286 KCFQCQNCRDILNPNSFWLHDNLSYCKNCYGELFTEICDKCQEKIW--KNLIRFRELNLH 459
CF+C C+ L F D+ C +CY F+ C C E + + + H
Sbjct: 64 GCFRCCRCQRSLADEPFTRQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWH 123
Query: 460 SECFICNVCDLGLTDKRFFYKNELIFCDNCYNENVARHAQDAKNTL 597
CF+C C+ L + F +C CY N A TL
Sbjct: 124 EHCFLCIGCEQPLGSRPFVPDKGAHYCVPCYENNFAPRCARCTKTL 169
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,865,695
Number of Sequences: 369166
Number of extensions: 1398504
Number of successful extensions: 5324
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4365
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4895
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4846822695
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)