Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_C13
(569 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 35 0.13
sp|Q58CY8|TSN18_BOVIN Tetraspanin-18 (Tspan-18) 35 0.13
sp|Q9D7W4|TSN17_MOUSE Tetraspanin-17 (Tspan-17) (Transmembr... 34 0.22
sp|Q9XSK2|CD63_BOVIN CD63 antigen 33 0.38
sp|Q96SJ8|TSN18_HUMAN Tetraspanin-18 (Tspan-18) 33 0.38
sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane... 33 0.38
sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antige... 33 0.50
sp|Q80WR1|TSN18_MOUSE Tetraspanin-18 (Tspan-18) 33 0.65
sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen... 32 0.85
sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen ... 32 1.1
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491)
(Lysosome-associated membrane glycoprotein 3) (LAMP-3)
(Ocular melanoma-associated antigen) (OMA81H)
(Granulophysin) (Tetraspanin-30) (Tspan-30)
Length = 238
Score = 35.0 bits (79), Expect = 0.13
Identities = 19/73 (26%), Positives = 37/73 (50%)
Frame = +1
Query: 10 KLPDSCCKMKGGQIENVGICRQGNENGIHENGCMTVVMKSIGEQYIIVLSALITLAVVLI 189
++PDSCC VG NE IH+ GC+ + + + ++V +A + +A V +
Sbjct: 164 RVPDSCCINV-----TVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEV 218
Query: 190 FGMCLSLAHLRNI 228
G+ + +++I
Sbjct: 219 LGIVFACCLVKSI 231
>sp|Q58CY8|TSN18_BOVIN Tetraspanin-18 (Tspan-18)
Length = 249
Score = 35.0 bits (79), Expect = 0.13
Identities = 20/79 (25%), Positives = 43/79 (54%), Gaps = 5/79 (6%)
Frame = +1
Query: 10 KLPDSCCKMKGGQIENVGICRQ----GNENGIHENGCMTVVMKSIGEQYIIVLSAL-ITL 174
++P++CC+ + + V + R+ G + +++ GC TV++ + E Y+ + AL I +
Sbjct: 171 EVPEACCRREPQSRDGVLLSREECLLGRDLFLNKQGCYTVILNAF-ETYVYLAGALAIGV 229
Query: 175 AVVLIFGMCLSLAHLRNII 231
+ +F M ++ R II
Sbjct: 230 LAIELFAMIFAMCLFRGII 248
>sp|Q9D7W4|TSN17_MOUSE Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17)
(Tetraspan protein SB134) (F-box only protein 23)
Length = 270
Score = 34.3 bits (77), Expect = 0.22
Identities = 16/55 (29%), Positives = 31/55 (56%)
Frame = +1
Query: 82 ENGIHENGCMTVVMKSIGEQYIIVLSALITLAVVLIFGMCLSLAHLRNIINIRYN 246
E I+ GC+ K + + I+V L+ +A++ IFG+CL+ + +I ++ N
Sbjct: 215 EGSIYTKGCVGQFEKWLQDNLIVVAGVLVGIALLQIFGLCLAQNLVSDIKAVKAN 269
>sp|Q9XSK2|CD63_BOVIN CD63 antigen
Length = 237
Score = 33.5 bits (75), Expect = 0.38
Identities = 21/73 (28%), Positives = 37/73 (50%)
Frame = +1
Query: 10 KLPDSCCKMKGGQIENVGICRQGNENGIHENGCMTVVMKSIGEQYIIVLSALITLAVVLI 189
K+PDSCC N GI IH GC+ + + + ++V++A + +A V I
Sbjct: 163 KVPDSCCV---NITHNCGI--NFVVKDIHTEGCVEKIAAWLRKNVLVVVAAALGIAFVEI 217
Query: 190 FGMCLSLAHLRNI 228
G+ L+ +++I
Sbjct: 218 LGIVLACCLVKSI 230
>sp|Q96SJ8|TSN18_HUMAN Tetraspanin-18 (Tspan-18)
Length = 248
Score = 33.5 bits (75), Expect = 0.38
Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 9/74 (12%)
Frame = +1
Query: 10 KLPDSCCKMKGGQIENVGICRQ----GNENGIHENGCMTVVMKSIGEQYIIVLSALI--T 171
++P++CC+ + + V + R+ G +++ GC TV++ + E Y+ + AL
Sbjct: 171 EVPEACCRREPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTF-ETYVYLAGALAIGV 229
Query: 172 LAV---VLIFGMCL 204
LA+ +IF MCL
Sbjct: 230 LAIELFAMIFAMCL 243
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
Length = 245
Score = 33.5 bits (75), Expect = 0.38
Identities = 21/76 (27%), Positives = 35/76 (46%)
Frame = +1
Query: 16 PDSCCKMKGGQIENVGICRQGNENGIHENGCMTVVMKSIGEQYIIVLSALITLAVVLIFG 195
P SCCK++ G Q + + ++E GC VM +I + +V +A + G
Sbjct: 174 PKSCCKLE-------GCYPQRDADKVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIG 226
Query: 196 MCLSLAHLRNIINIRY 243
+ L+ R I N +Y
Sbjct: 227 IFLAYCLSRAITNNQY 242
>sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen) (Tetraspanin-24)
(Tspan-24)
Length = 253
Score = 33.1 bits (74), Expect = 0.50
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +1
Query: 13 LPDSCCKMKGGQIENVGICRQGNE-NGIH--ENGCMTVVMKSIGEQYIIVLSALITLAVV 183
+PDSCCK V +C Q + + I+ E GC+T + I E ++ + I +A V
Sbjct: 180 VPDSCCKTV------VALCGQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACV 233
Query: 184 LIFGMCLSLAHLRNI 228
+FGM + R++
Sbjct: 234 QVFGMIFTCCLYRSL 248
>sp|Q80WR1|TSN18_MOUSE Tetraspanin-18 (Tspan-18)
Length = 248
Score = 32.7 bits (73), Expect = 0.65
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 9/74 (12%)
Frame = +1
Query: 10 KLPDSCCKMKGGQIENVGI----CRQGNENGIHENGCMTVVMKSIGEQYIIVLSALI--T 171
++P +CC+ + + V + C+ G I++ GC TV++ + E Y+ + A
Sbjct: 171 EVPKACCRREPQTRDGVVLSREECQLGRNPFINKQGCYTVILNTF-ETYVYLAGAFAIGV 229
Query: 172 LAV---VLIFGMCL 204
LA+ +++F MCL
Sbjct: 230 LAIELFLMVFAMCL 243
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen)
Length = 253
Score = 32.3 bits (72), Expect = 0.85
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Frame = +1
Query: 13 LPDSCCKMKGGQIENVGICRQGNENGIH--ENGCMTVVMKSIGEQYIIVLSALITLAVVL 186
+PDSCCK G ++ + + I+ E GC+T + I E ++ + I +A V
Sbjct: 180 VPDSCCKTMVA-----GCGKRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQ 234
Query: 187 IFGMCLSLAHLRNI 228
+FGM + R++
Sbjct: 235 VFGMIFTCCLYRSL 248
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen)
Length = 253
Score = 32.0 bits (71), Expect = 1.1
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Frame = +1
Query: 13 LPDSCCKMKGGQIENVGICRQGNENGIH--ENGCMTVVMKSIGEQYIIVLSALITLAVVL 186
+PDSCCK G ++ + + I+ E GC+T + I E ++ + I +A V
Sbjct: 180 VPDSCCKTVV-----TGCGKREHASNIYKVEGGCITKLESFIQEHLRVIGAVGIGIACVQ 234
Query: 187 IFGMCLSLAHLRNI 228
+FGM + R++
Sbjct: 235 VFGMIFTCCLYRSL 248
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,182,927
Number of Sequences: 369166
Number of extensions: 1174336
Number of successful extensions: 2398
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2354
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2394
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4177115900
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)