Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_026_B18 (388 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen ... 52 5e-07 sp|Q9XSK2|CD63_BOVIN CD63 antigen 51 7e-07 sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen... 50 2e-06 sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antige... 49 3e-06 sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane... 48 6e-06 sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 48 8e-06 sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane... 47 1e-05 sp|Q28709|CD63_RABIT CD63 antigen 47 1e-05 sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 47 2e-05 sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane... 44 1e-04
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen) Length = 253 Score = 51.6 bits (122), Expect = 5e-07 Identities = 22/91 (24%), Positives = 47/91 (51%), Gaps = 2/91 (2%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAF--TDGCIPKMFSYA 176 G+ DW S+W ++ + ++ P SCC + + C + + + GCI K+ S+ Sbjct: 157 GSNNSRDWRDSEWIRSGEADSRVVPDSCCKTVVTGCGKREHASNIYKVEGGCITKLESFI 216 Query: 177 KTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 269 + + ++ + +GIA ++F ++ CL R+ Sbjct: 217 QEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|Q9XSK2|CD63_BOVIN CD63 antigen Length = 237 Score = 51.2 bits (121), Expect = 7e-07 Identities = 30/89 (33%), Positives = 42/89 (47%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKT 182 GA TDW + T P SCC IT C K T+GC+ K+ ++ + Sbjct: 147 GAANYTDW------EKILAVTNKVPDSCCVNITHNCGINFVVKDIHTEGCVEKIAAWLRK 200 Query: 183 YFPLVIGITLGIAFFEIFVVVCAFCLCRN 269 +V+ LGIAF EI +V A CL ++ Sbjct: 201 NVLVVVAAALGIAFVEILGIVLACCLVKS 229
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane glycoprotein SFA-1) (CD151 antigen) Length = 253 Score = 50.1 bits (118), Expect = 2e-06 Identities = 21/91 (23%), Positives = 47/91 (51%), Gaps = 2/91 (2%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAF--TDGCIPKMFSYA 176 G+ DW S+W ++ + ++ P SCC + + C + + + GCI K+ ++ Sbjct: 157 GSNNSQDWQDSEWIRSGEADSRVVPDSCCKTMVAGCGKRDHASNIYKVEGGCITKLETFI 216 Query: 177 KTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 269 + + ++ + +GIA ++F ++ CL R+ Sbjct: 217 QEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane glycoprotein SFA-1) (CD151 antigen) (Tetraspanin-24) (Tspan-24) Length = 253 Score = 49.3 bits (116), Expect = 3e-06 Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAF--TDGCIPKMFSYA 176 G+ DW S+W ++ + + P SCC + + C + + + GCI K+ ++ Sbjct: 157 GSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKVEGGCITKLETFI 216 Query: 177 KTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 269 + + ++ + +GIA ++F ++ CL R+ Sbjct: 217 QEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6) (T245 protein) (Tetraspanin TM4-D) (A15 homolog) Length = 245 Score = 48.1 bits (113), Expect = 6e-06 Identities = 26/94 (27%), Positives = 43/94 (45%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKT 182 G T DW +++Y + FP SCC C K +GC K+ + ++ Sbjct: 155 GVTDYRDWTDTNYYSE-----KGFPKSCCK--LEDCTPQRDADKVNNEGCFIKVMTIIES 207 Query: 183 YFPLVIGITLGIAFFEIFVVVCAFCLCRNTVQHQ 284 +V GI+ G+A F++ + A+CL R +Q Sbjct: 208 EMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491) (Lysosome-associated membrane glycoprotein 3) (LAMP-3) (Ocular melanoma-associated antigen) (OMA81H) (Granulophysin) (Tetraspanin-30) (Tspan-30) Length = 238 Score = 47.8 bits (112), Expect = 8e-06 Identities = 29/89 (32%), Positives = 43/89 (48%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKT 182 GA TDW + SKN+ P SCC +T C +K +GC+ K+ + + Sbjct: 147 GAANYTDWEKIP--SMSKNRV---PDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRK 201 Query: 183 YFPLVIGITLGIAFFEIFVVVCAFCLCRN 269 +V LGIAF E+ +V A CL ++ Sbjct: 202 NVLVVAAAALGIAFVEVLGIVFACCLVKS 230
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6) Length = 245 Score = 47.4 bits (111), Expect = 1e-05 Identities = 26/94 (27%), Positives = 44/94 (46%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKT 182 G T DW +++Y + FP SCC C+ K +GC K+ + ++ Sbjct: 155 GVTNYGDWKGTNYYSETG-----FPKSCCK--LEGCYPQRDADKVNEEGCFIKVMTTIES 207 Query: 183 YFPLVIGITLGIAFFEIFVVVCAFCLCRNTVQHQ 284 +V GI+ G+A F++ + A+CL R +Q Sbjct: 208 EMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241
>sp|Q28709|CD63_RABIT CD63 antigen Length = 238 Score = 47.4 bits (111), Expect = 1e-05 Identities = 27/89 (30%), Positives = 40/89 (44%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKT 182 GA TDW + P SCC +TS C K + +GC+ K+ + + Sbjct: 147 GAANYTDWATIPGMTRDR-----VPDSCCVNVTSGCGVKFNVKDIYVEGCVEKIGLWLRK 201 Query: 183 YFPLVIGITLGIAFFEIFVVVCAFCLCRN 269 +V LGIAF E+ +V A CL ++ Sbjct: 202 NVLVVAAAALGIAFVEVLGIVFACCLVKS 230
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) Length = 238 Score = 46.6 bits (109), Expect = 2e-05 Identities = 26/89 (29%), Positives = 41/89 (46%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDGCIPKMFSYAKT 182 GA+ TDW + + P SCC IT C + T GC+ + ++ + Sbjct: 147 GASNYTDWERIPGMAKDR-----VPDSCCINITVGCGNDFKESTIHTQGCVETIAAWLRK 201 Query: 183 YFPLVIGITLGIAFFEIFVVVCAFCLCRN 269 LV G LGIAF E+ ++ + CL ++ Sbjct: 202 NVLLVAGAALGIAFVEVLGIIFSCCLVKS 230
>sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8) (Tetraspanin TM4-A) Length = 253 Score = 43.9 bits (102), Expect = 1e-04 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Frame = +3 Query: 3 GATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPC-WELGYDKKAFTDGCIPKMFSYAK 179 G +DW +DW++ +KN Q P SCC S C L + + +GC + + Sbjct: 149 GIHNYSDWENTDWFKETKN--QSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQ 206 Query: 180 TYFPLVIGITLGIAFFEIFVVVCA-FCLCRNT 272 VI L A ++ ++CA LCR + Sbjct: 207 EIMMHVIWAALAFAAIQLLGMLCACIVLCRRS 238
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,180,285 Number of Sequences: 369166 Number of extensions: 882522 Number of successful extensions: 2252 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2214 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2247 length of database: 68,354,980 effective HSP length: 95 effective length of database: 50,805,155 effective search space used: 1676570115 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)