Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_A04
(483 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP... 140 2e-33
sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP... 137 1e-32
sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP I... 136 2e-32
sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precur... 94 2e-19
sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precur... 94 2e-19
sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precur... 93 4e-19
sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor 89 5e-18
sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor 66 4e-11
sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor 58 1e-08
sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor 56 4e-08
>sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 506
Score = 140 bits (352), Expect = 2e-33
Identities = 69/140 (49%), Positives = 96/140 (68%)
Frame = +1
Query: 1 GCGLGPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQL 180
GCG G D+ AWD+QACTE+ L DSN + DMFP++P + + ++C+ + V + L
Sbjct: 347 GCGTGSDARAWDYQACTEINLTFDSNNVT-DMFPEIPFSEELRQQYCLDTWGVWPRQDWL 405
Query: 181 KYLEWGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPA 360
+ WG ++ A+NIIFSNGDLDPW+ GGI N L +S +A+ I+GGAHHLDLR+SN
Sbjct: 406 QTSFWGGDLKAASNIIFSNGDLDPWAGGGIQSN--LSTSVIAVTIQGGAHHLDLRASNSE 463
Query: 361 DPPSVQQARQSEEFYIRKWL 420
DPPSV + R+ E IR+W+
Sbjct: 464 DPPSVVEVRKLESTLIREWV 483
>sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 492
Score = 137 bits (346), Expect = 1e-32
Identities = 71/140 (50%), Positives = 95/140 (67%)
Frame = +1
Query: 1 GCGLGPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQL 180
GCG GPD+ AWD+QACTE+ L SN + DMFPDLP T + ++C+ + V + L
Sbjct: 337 GCGTGPDARAWDYQACTEINLTFASNNVT-DMFPDLPFTDELRQRYCLDTWGVWPRPDWL 395
Query: 181 KYLEWGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPA 360
WG +R A+NIIFSNG+LDPW+ GGI N L +S +A+ I+GGAHHLDLR+S+P
Sbjct: 396 LTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRN--LSASVIAVTIQGGAHHLDLRASHPE 453
Query: 361 DPPSVQQARQSEEFYIRKWL 420
DP SV +AR+ E I +W+
Sbjct: 454 DPASVVEARKLEATIIGEWV 473
>sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 500
Score = 136 bits (343), Expect = 2e-32
Identities = 68/140 (48%), Positives = 96/140 (68%)
Frame = +1
Query: 1 GCGLGPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQL 180
GCG G ++ AWD+QACTE+ L DSN + DMFP++P + + ++C+ + V + L
Sbjct: 347 GCGTGSNARAWDYQACTEINLTFDSNNVT-DMFPEIPFSDELRQQYCLDTWGVWPRPDWL 405
Query: 181 KYLEWGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPA 360
+ WG ++ A+NIIFSNGDLDPW+ GGI N L +S +A+ I+GGAHHLDLR+SN
Sbjct: 406 QTSFWGGDLKAASNIIFSNGDLDPWAGGGIQRN--LSTSIIAVTIQGGAHHLDLRASNSE 463
Query: 361 DPPSVQQARQSEEFYIRKWL 420
DPPSV + R+ E IR+W+
Sbjct: 464 DPPSVVEVRKLEATLIREWV 483
>sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase)
Length = 496
Score = 94.0 bits (232), Expect = 2e-19
Identities = 49/135 (36%), Positives = 79/135 (58%)
Frame = +1
Query: 22 SLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGD 201
+L W +QACTE+ + +N DMF +++ C +++ V + + + G
Sbjct: 356 TLGWSYQACTEVVMPFCTNGVD-DMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGK 414
Query: 202 YVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQ 381
+ + TNI+FSNG+LDPWS GG+T++ + + VA+ I GAHHLDLR+ N DP SV
Sbjct: 415 NISSHTNIVFSNGELDPWSGGGVTKD--ITDTLVAVTISEGAHHLDLRTKNALDPTSVLL 472
Query: 382 ARQSEEFYIRKWLNE 426
AR E +++ W+ +
Sbjct: 473 ARSLEVRHMKNWIRD 487
>sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase) (Angiotensinase C)
(Lysosomal carboxypeptidase C)
Length = 496
Score = 93.6 bits (231), Expect = 2e-19
Identities = 49/135 (36%), Positives = 79/135 (58%)
Frame = +1
Query: 22 SLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGD 201
+L W +QACTE+ + +N DMF +++ C +++ V + + + G
Sbjct: 356 TLGWSYQACTEVVMPFCTNGVD-DMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGK 414
Query: 202 YVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQ 381
+ + TNI+FSNG+LDPWS GG+T++ + + VA+ I GAHHLDLR+ N DP SV
Sbjct: 415 NISSHTNIVFSNGELDPWSGGGVTKD--ITDTLVAVTISEGAHHLDLRTKNALDPMSVLL 472
Query: 382 ARQSEEFYIRKWLNE 426
AR E +++ W+ +
Sbjct: 473 ARSLEVRHMKNWIRD 487
>sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase)
Length = 491
Score = 92.8 bits (229), Expect = 4e-19
Identities = 51/133 (38%), Positives = 76/133 (57%)
Frame = +1
Query: 22 SLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGD 201
S+ W FQACTEM + +N DMF ++ C ++ V + + + G
Sbjct: 354 SMGWSFQACTEMVMPFCTNGID-DMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGK 412
Query: 202 YVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQ 381
+ + +NIIFSNG+LDPWS GG+T + + + VA+ I GAHHLDLR+ N DP SV
Sbjct: 413 NISSHSNIIFSNGELDPWSGGGVTRD--ITDTLVAINIHDGAHHLDLRAHNAFDPSSVLL 470
Query: 382 ARQSEEFYIRKWL 420
+R E +++KW+
Sbjct: 471 SRLLEVKHMKKWI 483
>sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor
Length = 507
Score = 89.0 bits (219), Expect = 5e-18
Identities = 51/143 (35%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Frame = +1
Query: 19 DSLAWDFQACTEMKLYDDSNATSGDMF-PDLPLTRQQVDKHCIKKFE-VDRADNQLKYLE 192
D L W FQ CTEM + + D F D P T ++ + C++ F + L+ L
Sbjct: 356 DPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLA 415
Query: 193 WG-----DYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNP 357
G + +A+NI+FSNG LDPWS GG + + S +++ +K GAHH DLR ++P
Sbjct: 416 GGLAFGATSLPSASNIVFSNGYLDPWSGGGYDHSDKVQGSVISVILKQGAHHYDLRGAHP 475
Query: 358 ADPPSVQQARQSEEFYIRKWLNE 426
D V++ R E I+KW+ E
Sbjct: 476 QDTEEVKKVRAMETQAIKKWIKE 498
>sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor
Length = 565
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/149 (30%), Positives = 73/149 (48%), Gaps = 8/149 (5%)
Frame = +1
Query: 7 GLGPDSLAWDFQACTEMKLYDDSNATSGDMF-----PDLPLTRQQVDKHCIKKFEVDRAD 171
GLG D L W +Q C+E+ + ++ S D+F D+ T QQ K +
Sbjct: 364 GLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIFKSMGWTPKN 423
Query: 172 NQLKYLE--WGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSV-ALWIKGGAHHLDL 342
+ ++ +G + ++N+I + G LDPWS GG + + + + L I G AHHLDL
Sbjct: 424 WNIDAVKTLYGYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDL 483
Query: 343 RSSNPADPPSVQQARQSEEFYIRKWLNEN 429
R N DP +V AR ++ W++ N
Sbjct: 484 RQPNTCDPNTVTNARFQIIQILKCWVDPN 512
>sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor
Length = 514
Score = 57.8 bits (138), Expect = 1e-08
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
Frame = +1
Query: 31 WDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLE----WG 198
W +Q CTE Y F LP Q+D C + F + + +G
Sbjct: 373 WLYQTCTEFGFYVTCENPRCP-FSQLPALPSQLDL-CEQVFGLSALSVAQAVAQTNSYYG 430
Query: 199 DYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQ 378
A ++F NGD DPW + +T+ +L SS L I+ G+H LD+ P+D PS++
Sbjct: 431 GQTPGANKVLFVNGDTDPWHVLSVTQ--ALGSSESTLLIRTGSHCLDMAPERPSDSPSLR 488
Query: 379 QARQSEEFYIRKWL 420
RQ+ ++ WL
Sbjct: 489 LGRQNIFQQLQTWL 502
>sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor
Length = 509
Score = 56.2 bits (134), Expect = 4e-08
Identities = 39/136 (28%), Positives = 59/136 (43%), Gaps = 4/136 (2%)
Frame = +1
Query: 31 WDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVR 210
W +Q CTE Y F LP Q++ C + F + A + Y
Sbjct: 372 WLYQTCTEFGFYVTCEGLQCP-FSQLPALPFQLEL-CEQVFGLSPASVAQAVAQTNSYYG 429
Query: 211 T----ATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQ 378
AT ++F NGD DPW + +T++ L S AL I +H D+ P+D PS++
Sbjct: 430 GQSPGATQVLFVNGDTDPWHVLSVTQDLGL--SEPALLIPSASHCFDMAPMRPSDSPSLR 487
Query: 379 QARQSEEFYIRKWLNE 426
RQ ++ WL +
Sbjct: 488 LGRQKISQQLQDWLKD 503
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,428,638
Number of Sequences: 369166
Number of extensions: 1217811
Number of successful extensions: 3117
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3016
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3093
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2871696580
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)