Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_P22
(622 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75494|FUSIP_HUMAN FUS-interacting serine-arginine-rich ... 92 8e-19
sp|Q8WXF0|SRR35_HUMAN 35 kDa SR repressor protein (SRrp35) 88 2e-17
sp|O22315|SFRS1_ARATH Pre-mRNA splicing factor SF2 (SR1 pro... 75 1e-13
sp|Q9NEW6|RSP3_CAEEL Probable splicing factor, arginine/ser... 67 4e-11
sp|P27476|NSR1_YEAST Nuclear localization sequence binding ... 64 2e-10
sp|Q8C7E9|CSTFT_MOUSE Cleavage stimulation factor, 64 kDa s... 62 2e-09
sp|Q9H0L4|CSTFT_HUMAN Cleavage stimulation factor, 64 kDa s... 62 2e-09
sp|Q18409|RSP6_CAEEL Probable splicing factor, arginine/ser... 61 3e-09
sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich... 60 6e-09
sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2... 60 6e-09
>sp|O75494|FUSIP_HUMAN FUS-interacting serine-arginine-rich protein 1 (TLS-associated
protein with Ser-Arg repeats) (TLS-associated protein
with SR repeats) (TASR) (TLS-associated serine-arginine
protein) (TLS-associated SR protein) (40 kDa
SR-repressor protein) (SRrp40) (Splicing factor SRp38)
sp|Q9R0U0|FUSIP_MOUSE FUS-interacting serine-arginine-rich protein 1 (TLS-associated
protein with Ser-Arg repeats) (TLS-associated protein
with SR repeats) (TASR) (TLS-associated serine-arginine
protein) (TLS-associated SR protein) (Neural-specific SR
protein) (Neural-salient serine/arginine-rich protein)
Length = 262
Score = 92.4 bits (228), Expect = 8e-19
Identities = 42/97 (43%), Positives = 69/97 (71%)
Frame = +3
Query: 24 STTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESF 203
+T+++V N+ +D R ++L+R FGRYG IV +P+D+Y+ P+GFA+VQFED+RDAE++
Sbjct: 9 NTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
Query: 204 DRLQGYRIGKRSLRLEFATGTKKTPDEMRTVTRRGRS 314
L I R + ++FA G +KTP++M+ + GR+
Sbjct: 69 HNLDRKWICGRQIEIQFAQGDRKTPNQMK--AKEGRN 103
>sp|Q8WXF0|SRR35_HUMAN 35 kDa SR repressor protein (SRrp35)
Length = 261
Score = 88.2 bits (217), Expect = 2e-17
Identities = 40/99 (40%), Positives = 67/99 (67%)
Frame = +3
Query: 24 STTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESF 203
+T++++ N+ + R ++L+R FGRYG IV +P+D+Y+ P+GFA+VQFED+RDAE++
Sbjct: 9 NTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDAL 68
Query: 204 DRLQGYRIGKRSLRLEFATGTKKTPDEMRTVTRRGRSNS 320
L + R + ++FA G +KTP +M++ R S S
Sbjct: 69 YNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPS 107
>sp|O22315|SFRS1_ARATH Pre-mRNA splicing factor SF2 (SR1 protein)
Length = 303
Score = 75.5 bits (184), Expect = 1e-13
Identities = 38/91 (41%), Positives = 56/91 (61%)
Frame = +3
Query: 18 RSSTTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEE 197
RSS T+YVGN+P D+R E++ +F +YG +V L V P G+AFV+F+D RDAE+
Sbjct: 4 RSSRTVYVGNLPGDIREREVEDLFSKYGPVVQIDLKVPPR---PPGYAFVEFDDARDAED 60
Query: 198 SFDRLQGYRIGKRSLRLEFATGTKKTPDEMR 290
+ GY LR+E A G +++ D+ R
Sbjct: 61 AIHGRDGYDFDGHRLRVELAHGGRRSSDDTR 91
>sp|Q9NEW6|RSP3_CAEEL Probable splicing factor, arginine/serine-rich 3 (CeSF2)
(CeSF2/ASF)
Length = 258
Score = 67.0 bits (162), Expect = 4e-11
Identities = 38/87 (43%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 12 MPRSSTT---IYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDI 182
MPR + +YVGN+P D+R E++ IF +YG I VD SG FAFV+FED
Sbjct: 1 MPRGGSEDQKVYVGNLPGDVREKEVEDIFHKYGRIKY----VDIKSGRGPAFAFVEFEDH 56
Query: 183 RDAEESFDRLQGYRIGKRSLRLEFATG 263
RDAE++ GY R +R+EF G
Sbjct: 57 RDAEDAVRARDGYEFDGRRIRVEFTRG 83
>sp|P27476|NSR1_YEAST Nuclear localization sequence binding protein (P67)
Length = 414
Score = 64.3 bits (155), Expect = 2e-10
Identities = 28/79 (35%), Positives = 51/79 (64%)
Frame = +3
Query: 24 STTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESF 203
S T+++GN+ + RD + +F ++G +V+ +P + PKGF +VQF ++ DA+++
Sbjct: 266 SDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKAL 325
Query: 204 DRLQGYRIGKRSLRLEFAT 260
D LQG I R +RL+F++
Sbjct: 326 DALQGEYIDNRPVRLDFSS 344
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/77 (25%), Positives = 40/77 (51%)
Frame = +3
Query: 30 TIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDR 209
TI+VG + + + LK+ F G ++ A + + + +G+ +V FE+ AE++
Sbjct: 169 TIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQE 228
Query: 210 LQGYRIGKRSLRLEFAT 260
+QG I R + + +T
Sbjct: 229 MQGKEIDGRPINCDMST 245
>sp|Q8C7E9|CSTFT_MOUSE Cleavage stimulation factor, 64 kDa subunit, tau variant (CSTF 64
kDa subunit, tau variant) (CF-1 64 kDa subunit, tau
variant) (TauCstF-64)
Length = 632
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/95 (32%), Positives = 56/95 (58%)
Frame = +3
Query: 12 MPRSSTTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDA 191
M RS +++VGNIP + ++LK IF G++V+ L D +G PKG+ F +++D A
Sbjct: 11 MDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETA 70
Query: 192 EESFDRLQGYRIGKRSLRLEFATGTKKTPDEMRTV 296
+ L G R+LR++ A ++K +E++++
Sbjct: 71 LSAMRNLNGREFSGRALRVDNA-ASEKNKEELKSL 104
>sp|Q9H0L4|CSTFT_HUMAN Cleavage stimulation factor, 64 kDa subunit, tau variant (CSTF 64
kDa subunit, tau variant) (CF-1 64 kDa subunit, tau
variant) (TauCstF-64)
Length = 616
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/95 (32%), Positives = 56/95 (58%)
Frame = +3
Query: 12 MPRSSTTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDA 191
M RS +++VGNIP + ++LK IF G++V+ L D +G PKG+ F +++D A
Sbjct: 11 MDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETA 70
Query: 192 EESFDRLQGYRIGKRSLRLEFATGTKKTPDEMRTV 296
+ L G R+LR++ A ++K +E++++
Sbjct: 71 LSAMRNLNGREFSGRALRVDNA-ASEKNKEELKSL 104
>sp|Q18409|RSP6_CAEEL Probable splicing factor, arginine/serine-rich 6 (RNA-binding
protein srp-1) (CeSRp20)
Length = 179
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/80 (38%), Positives = 47/80 (58%)
Frame = +3
Query: 33 IYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFDRL 212
+YVG +P D EL+ IF R+G I + + P GFAFV+++D+RDAE++ L
Sbjct: 5 VYVGGLPSDATSQELEEIFDRFGRIRKV-----WVARRPPGFAFVEYDDVRDAEDAVRAL 59
Query: 213 QGYRIGKRSLRLEFATGTKK 272
G RI R+E +TG ++
Sbjct: 60 DGSRICGVRARVELSTGQRR 79
>sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa) (PR264 protein)
Length = 221
Score = 59.7 bits (143), Expect = 6e-09
Identities = 29/77 (37%), Positives = 46/77 (59%)
Frame = +3
Query: 27 TTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFD 206
T++ V N+ D L+R+F +YG + +P D Y+ +GFAFV+F D RDAE++ D
Sbjct: 14 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 73
Query: 207 RLQGYRIGKRSLRLEFA 257
+ G + R LR++ A
Sbjct: 74 AMDGAVLDGRELRVQMA 90
>sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa)
sp|Q62093|SFRS2_MOUSE Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa) (PR264 protein)
sp|Q01130|SFRS2_HUMAN Splicing factor, arginine/serine-rich 2 (Splicing factor SC35)
(SC-35) (Splicing component, 35 kDa) (PR264 protein)
Length = 221
Score = 59.7 bits (143), Expect = 6e-09
Identities = 29/77 (37%), Positives = 46/77 (59%)
Frame = +3
Query: 27 TTIYVGNIPEDLRRDELKRIFGRYGNIVAATLPVDYYSGIPKGFAFVQFEDIRDAEESFD 206
T++ V N+ D L+R+F +YG + +P D Y+ +GFAFV+F D RDAE++ D
Sbjct: 14 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMD 73
Query: 207 RLQGYRIGKRSLRLEFA 257
+ G + R LR++ A
Sbjct: 74 AMDGAVLDGRELRVQMA 90
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,311,318
Number of Sequences: 369166
Number of extensions: 1009868
Number of successful extensions: 3347
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3003
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3262
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4877307000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)