Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_P07
(655 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P58058|NADK_MOUSE NAD kinase (Poly(P)/ATP NAD kinase) 183 4e-46
sp|O95544|NADK_HUMAN NAD kinase (Poly(P)/ATP NAD kinase) 179 4e-45
sp|P32622|YEF1_YEAST Hypothetical 55.9 kDa protein in GDA1-... 144 3e-34
sp|P21373|UTR1_YEAST NAD(+) kinase (Unknown transcript 1 pr... 132 1e-30
sp|O13863|YDU2_SCHPO Hypothetical protein C1B1.02c in chrom... 130 4e-30
sp|Q06892|POS5_YEAST POS5 protein 124 3e-28
sp|Q82UK6|PPNK_NITEU Probable inorganic polyphosphate/ATP-N... 107 3e-23
sp|Q8XW25|PPNK_RALSO Probable inorganic polyphosphate/ATP-N... 107 4e-23
sp|Q9HZC0|PPNK_PSEAE Probable inorganic polyphosphate/ATP-N... 105 8e-23
sp|Q88LC3|PPNK_PSEPK Probable inorganic polyphosphate/ATP-N... 105 8e-23
>sp|P58058|NADK_MOUSE NAD kinase (Poly(P)/ATP NAD kinase)
Length = 439
Score = 183 bits (464), Expect = 4e-46
Identities = 99/226 (43%), Positives = 144/226 (63%), Gaps = 14/226 (6%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+GTLL AS F+ PP+MAF+LG+LGF+ PF E F+ + + ++GN ILR+RL
Sbjct: 185 DGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVR 244
Query: 189 VG--------------NVDEIITNGKSECFDNIALNDVVIDRGASNHILSLIIAVDNKFV 326
V + + + T G + LN+VVIDRG S+++ ++ + +D +
Sbjct: 245 VVKEPRDKKTAIHNGLSENGLDTEGGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLI 304
Query: 327 TKMSGDGLIISTPTGSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKI 506
T + GDG+I+STPTGSTAY+ AAGAS++HP+V A++VTPI SLS RPI++P G++LKI
Sbjct: 305 TTVQGDGVIVSTPTGSTAYAAAAGASMVHPNVPAIMVTPICPHSLSFRPIVVPAGVELKI 364
Query: 507 YLDPDARANTAHISFDGDNRHMTISKSQCVNISVSRYPVISMCSSD 644
L P+AR NTA +SFDG R I ++I+ S YP+ S+C D
Sbjct: 365 MLSPEAR-NTAWVSFDGRKR-QEIRHGDSISITTSCYPLPSICVCD 408
>sp|O95544|NADK_HUMAN NAD kinase (Poly(P)/ATP NAD kinase)
Length = 446
Score = 179 bits (455), Expect = 4e-45
Identities = 102/233 (43%), Positives = 146/233 (62%), Gaps = 21/233 (9%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+GTLL AS F+ PP+MAF+LG+LGF+ PF E F+ + + ++GN +LR+RL
Sbjct: 184 DGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVR 243
Query: 189 VGNVDEI------ITNGKSECFDNIA---------------LNDVVIDRGASNHILSLII 305
V V E+ + NG E A LN+VVIDRG S+++ ++ +
Sbjct: 244 V--VKELRGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDV 301
Query: 306 AVDNKFVTKMSGDGLIISTPTGSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLP 485
+D +T + GDG+I+STPTGSTAY+ AAGAS+IHP+V A+++TPI SLS RPI++P
Sbjct: 302 YLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVP 361
Query: 486 VGIDLKIYLDPDARANTAHISFDGDNRHMTISKSQCVNISVSRYPVISMCSSD 644
G++LKI L P+AR NTA +SFDG R I ++I+ S YP+ S+C D
Sbjct: 362 AGVELKIMLSPEAR-NTAWVSFDGRKR-QEIRHGDSISITTSCYPLPSICVRD 412
>sp|P32622|YEF1_YEAST Hypothetical 55.9 kDa protein in GDA1-UTR2 intergenic region
Length = 495
Score = 144 bits (362), Expect = 3e-34
Identities = 90/219 (41%), Positives = 135/219 (61%), Gaps = 8/219 (3%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+GT+L AS F PPI+ F LG+LGF+ F + FKE+L+ L + LR RL
Sbjct: 192 DGTVLFASSIFTKDVPPIVPFALGSLGFLTNFEFQNFKETLKHILTDEVRINLRMRLQCK 251
Query: 189 V--GNVDEI-ITNGKSECF-----DNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGD 344
+ N EI G+ C+ ++ LN+V IDRG + + L + ++ +TK+ GD
Sbjct: 252 LYRRNKPEIDAATGRKICYIDFISEHHVLNEVTIDRGPAPCLSLLELYGNDSLMTKVQGD 311
Query: 345 GLIISTPTGSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKIYLDPDA 524
GLI++TPTGSTAYSL+AG S+I PSV A+ VTPI +LS RPI+LP ++LK+ +D ++
Sbjct: 312 GLIVATPTGSTAYSLSAGGSLISPSVNAIAVTPICPHTLSFRPIILPDSMELKVRVDMNS 371
Query: 525 RANTAHISFDGDNRHMTISKSQCVNISVSRYPVISMCSS 641
R T+ ++FDG +R + + + V I+ S Y V ++ SS
Sbjct: 372 R-GTSWVNFDGKDR-VELKQGDYVVITASPYSVPTIESS 408
>sp|P21373|UTR1_YEAST NAD(+) kinase (Unknown transcript 1 protein)
Length = 530
Score = 132 bits (331), Expect = 1e-30
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 8/211 (3%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+GT+L S F+ PP+M+F+LG+LGF+ F E F+E L + + I LR RL
Sbjct: 213 DGTVLFVSSIFQRHVPPVMSFSLGSLGFLTNFKFEHFREDLPRIMNHKIKTNLRLRLECT 272
Query: 189 V--GNVDEIITN-GKSECF-----DNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGD 344
+ + E+ N GK C + LN+V IDRG S + L + D +T D
Sbjct: 273 IYRRHRPEVDPNTGKKICVVEKLSTHHILNEVTIDRGPSPFLSMLELYGDGSLMTVAQAD 332
Query: 345 GLIISTPTGSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKIYLDPDA 524
GLI +TPTGSTAYSL+AG S++ P+V A+ +TPI +LS RPI+LP I+LK+ + +
Sbjct: 333 GLIAATPTGSTAYSLSAGGSLVCPTVNAIALTPICPHALSFRPIILPESINLKVKVSMKS 392
Query: 525 RANTAHISFDGDNRHMTISKSQCVNISVSRY 617
RA A +FDG +R + + K + I S Y
Sbjct: 393 RA-PAWAAFDGKDR-IELQKGDFITICASPY 421
>sp|O13863|YDU2_SCHPO Hypothetical protein C1B1.02c in chromosome I
Length = 537
Score = 130 bits (326), Expect = 4e-30
Identities = 76/215 (35%), Positives = 126/215 (58%), Gaps = 4/215 (1%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+ L+AS F+ + PP+++F+ GF++ PI ++ ++L+ LR R +
Sbjct: 288 DSAALRASWLFQDVVPPVLSFSTAKAGFLSILPIAEYTKTLDLIFHRGFTVNLRMRFQCS 347
Query: 189 ----VGNVDEIITNGKSECFDNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGDGLII 356
VG I G+ LN+++IDRG + ++SL + V+N+++T + DG+ +
Sbjct: 348 IMRYVGEHSTHICEGQYS-----VLNELLIDRGPNPFMISLDLYVENEYITTLQSDGVCV 402
Query: 357 STPTGSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKIYLDPDARANT 536
STPTGSTAYS+AAG S+ HP + A+L++ I SLS RPI+LP + L+I + DAR+N
Sbjct: 403 STPTGSTAYSVAAGGSLCHPGIPAILISAICPHSLSFRPIILPDSMTLRIVVPLDARSN- 461
Query: 537 AHISFDGDNRHMTISKSQCVNISVSRYPVISMCSS 641
A +FDG +R + + ++IS S +P S+ S
Sbjct: 462 AWCAFDGHHR-IELGLGDYISISASSFPFPSVIRS 495
>sp|Q06892|POS5_YEAST POS5 protein
Length = 414
Score = 124 bits (310), Expect = 3e-28
Identities = 67/170 (39%), Positives = 105/170 (61%), Gaps = 4/170 (2%)
Frame = +3
Query: 9 EGTLLKASGYF-KMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCF 185
+GT+L F PP++AF LGTLGF++PF ++ K+ ++ + C+ R RL
Sbjct: 150 DGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLEC 209
Query: 186 NVGNVDE---IITNGKSECFDNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGDGLII 356
++ D I+T+ A+ND+ + RG S H+ +L I +D +F+T+ + DG+ +
Sbjct: 210 HLKKKDSNSSIVTH---------AMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVAL 260
Query: 357 STPTGSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKI 506
+TPTGSTAYSL+AG SI+ P V A+L+TPI SLS RP++LP ++I
Sbjct: 261 ATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRI 310
>sp|Q82UK6|PPNK_NITEU Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD
kinase)
Length = 296
Score = 107 bits (267), Expect = 3e-23
Identities = 64/207 (30%), Positives = 110/207 (53%), Gaps = 2/207 (0%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+GT+L + P++ N G LGF+ + E+L L G ++ NR+
Sbjct: 74 DGTMLNIARALVPFSVPLIGINQGRLGFLTDLTADTMHETLNDMLAGQF--VVENRMLLT 131
Query: 189 VGNVDEIITNGKSECFDNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGDGLIISTPT 368
V E+ NG+S F +A NDVV+ RG S+ ++ L + ++ ++V + DGLII+TPT
Sbjct: 132 V----EVTRNGES-VFKELAFNDVVLHRGISSGMIELEVHINGEYVYSLRSDGLIIATPT 186
Query: 369 GSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILL--PVGIDLKIYLDPDARANTAH 542
GSTAY+L++G I+HP + + + PI +LS RPI++ I++K++ + + T
Sbjct: 187 GSTAYALSSGGPILHPGLNLMTLVPICPHTLSNRPIVIGADATIEIKVHFTTEIKIYTDS 246
Query: 543 ISFDGDNRHMTISKSQCVNISVSRYPV 623
S+ + H + +C +PV
Sbjct: 247 HSWFDLSEHDRVFIQRCPETIKLLHPV 273
>sp|Q8XW25|PPNK_RALSO Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD
kinase)
Length = 302
Score = 107 bits (266), Expect = 4e-23
Identities = 64/182 (35%), Positives = 95/182 (52%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+GTLL + P++ N G LGFM P E L L G R+ L
Sbjct: 79 DGTLLGIGRHLAGASVPVIGVNHGRLGFMTDIPFEDVHNVLPDMLAGQYEAETRSLLQAQ 138
Query: 189 VGNVDEIITNGKSECFDNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGDGLIISTPT 368
V DE I F +A NDVV++R + ++ L ++VD F+ DGLI+STPT
Sbjct: 139 VVRDDETI-------FSALAFNDVVVNRSGFSGMVELAVSVDGFFMYNQRSDGLIVSTPT 191
Query: 369 GSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKIYLDPDARANTAHIS 548
GSTAY+L+AG I+HP++ +++ PI +LS RPI++P ++ I + A ++
Sbjct: 192 GSTAYALSAGGPILHPALSGLVLVPIAPHALSNRPIVIPHDAEVVIQV---TSGRDASVN 248
Query: 549 FD 554
FD
Sbjct: 249 FD 250
>sp|Q9HZC0|PPNK_PSEAE Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD
kinase)
Length = 295
Score = 105 bits (263), Expect = 8e-23
Identities = 64/199 (32%), Positives = 105/199 (52%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+G++L A+ P++ N G+LGF+ ++ + + + L G I+ +R
Sbjct: 72 DGSMLGAARALARHKVPVLGINRGSLGFLTDIRPDELEAKVGEVLDGQY--IVESRFL-- 127
Query: 189 VGNVDEIITNGKSECFDNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGDGLIISTPT 368
+D + G ALNDVV+ G S ++ + +D +FV DGLI++TPT
Sbjct: 128 ---LDAQVRRGIDSMGQGDALNDVVLHPGKSTRMIEFELYIDGQFVCSQKADGLIVATPT 184
Query: 369 GSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKIYLDPDARANTAHIS 548
GSTAY+L+AG I+HP + A+++ P+ LS RPI++ +LKI + P+ + +S
Sbjct: 185 GSTAYALSAGGPIMHPKLDAIVIVPMYPHMLSSRPIVVDGNSELKIVVSPNMQI-YPQVS 243
Query: 549 FDGDNRHMTISKSQCVNIS 605
DG N H T + V IS
Sbjct: 244 CDGQN-HFTCAPGDTVTIS 261
>sp|Q88LC3|PPNK_PSEPK Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD
kinase)
Length = 296
Score = 105 bits (263), Expect = 8e-23
Identities = 66/199 (33%), Positives = 104/199 (52%)
Frame = +3
Query: 9 EGTLLKASGYFKMICPPIMAFNLGTLGFMAPFPIEQFKESLEKTLKGNIPCILRNRLCFN 188
+G+LL A+ P++ N G LGF+ ++ ++ + + L G+ R L
Sbjct: 72 DGSLLGAARALARHNIPVLGINRGNLGFLTDIRPDELEQKVAEVLDGHYLVENRFLLQAE 131
Query: 189 VGNVDEIITNGKSECFDNIALNDVVIDRGASNHILSLIIAVDNKFVTKMSGDGLIISTPT 368
V E I G ALNDVV+ G S ++ I +D +FV DGLI++TPT
Sbjct: 132 VRRHHEAIGQGD-------ALNDVVLHPGKSTRMIEFEIYIDGQFVCSQKADGLIVATPT 184
Query: 369 GSTAYSLAAGASIIHPSVRAVLVTPINAFSLSMRPILLPVGIDLKIYLDPDARANTAHIS 548
GSTAY+L+AG I+HP + A+++ P+ +LS RPI++ +LKI + D + +S
Sbjct: 185 GSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDLQI-YPQVS 243
Query: 549 FDGDNRHMTISKSQCVNIS 605
DG N H T + + +S
Sbjct: 244 CDGQN-HFTCAPGDTITVS 261
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,340,772
Number of Sequences: 369166
Number of extensions: 1554191
Number of successful extensions: 3891
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3759
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3826
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5413810770
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)