Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_P04
(783 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P19109|RM62_DROME ATP-dependent RNA helicase P62 238 2e-62
sp|Q61656|DDX5_MOUSE Probable RNA-dependent helicase p68 (D... 231 2e-60
sp|P17844|DDX5_HUMAN Probable RNA-dependent helicase p68 (D... 231 2e-60
sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17... 228 1e-59
sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17... 228 1e-59
sp|P24782|DBP2_SCHPO Probable ATP-dependent RNA helicase DB... 220 3e-57
sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2 220 3e-57
sp|Q6C4D4|DBP2_YARLI Probable ATP-dependent RNA helicase DBP2 219 7e-57
sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2 215 1e-55
sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DB... 213 6e-55
>sp|P19109|RM62_DROME ATP-dependent RNA helicase P62
Length = 719
Score = 238 bits (606), Expect = 2e-62
Identities = 118/226 (52%), Positives = 157/226 (69%), Gaps = 5/226 (2%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI SQIR DRQTLMWSATWPKEV++LA+DFLG YIQ+NIGS +L AN
Sbjct: 439 RMLDMGFEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFLGNYIQINIGSLELSANH 498
Query: 181 DIEQFVEIVEDFSKDSRLVDIIKKY-----PLDKMIVFTETKKKADKICGLLRLSGFNSG 345
+I Q V++ ++FSK+ +L ++ K+I+F ETK++ D + +R G G
Sbjct: 499 NIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFIRSFGVRCG 558
Query: 346 SMHGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRI 525
++HGDKSQ +R+++L+ FR+ NILVATDVA+RGLDVD IK VIN+D+P EDYIHRI
Sbjct: 559 AIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKYVINFDYPQNSEDYIHRI 618
Query: 526 GRTARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVVPDGLYDMA 663
GRT RS +G S+ FF + + +A Q + L ++A
Sbjct: 619 GRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREANQEINPALENLA 664
>sp|Q61656|DDX5_MOUSE Probable RNA-dependent helicase p68 (DEAD-box protein p68)
(DEAD-box protein 5) (DEAD-box RNA helicase DEAD1)
(mDEAD1)
Length = 614
Score = 231 bits (588), Expect = 2e-60
Identities = 114/216 (52%), Positives = 153/216 (70%), Gaps = 3/216 (1%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEV++LA+DFL YI +NIG+ +L AN
Sbjct: 252 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANH 311
Query: 181 DIEQFVEIVEDFSKDSRLVDIIKKYPLDK---MIVFTETKKKADKICGLLRLSGFNSGSM 351
+I Q V++ D KD +L+ ++++ +K IVF ETK++ D++ +R G+ + +
Sbjct: 312 NILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGI 371
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDKSQ++R+++L F++ IL+ATDVASRGLDV+D+K VINYD+PN EDYIHRIGR
Sbjct: 372 HGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGR 431
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVV 639
TARS K G +YTFF + +A Q +
Sbjct: 432 TARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAI 467
>sp|P17844|DDX5_HUMAN Probable RNA-dependent helicase p68 (DEAD-box protein p68)
(DEAD-box protein 5)
Length = 614
Score = 231 bits (588), Expect = 2e-60
Identities = 114/216 (52%), Positives = 153/216 (70%), Gaps = 3/216 (1%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEV++LA+DFL YI +NIG+ +L AN
Sbjct: 252 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANH 311
Query: 181 DIEQFVEIVEDFSKDSRLVDIIKKYPLDK---MIVFTETKKKADKICGLLRLSGFNSGSM 351
+I Q V++ D KD +L+ ++++ +K IVF ETK++ D++ +R G+ + +
Sbjct: 312 NILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGI 371
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDKSQ++R+++L F++ IL+ATDVASRGLDV+D+K VINYD+PN EDYIHRIGR
Sbjct: 372 HGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGR 431
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVV 639
TARS K G +YTFF + +A Q +
Sbjct: 432 TARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAI 467
>sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17 (DEAD-box protein 17)
(RNA-dependent helicase p72) (DEAD-box protein p72)
Length = 650
Score = 228 bits (581), Expect = 1e-59
Identities = 111/216 (51%), Positives = 152/216 (70%), Gaps = 3/216 (1%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEV++LA+DFL Y Q+N+G+ +L AN
Sbjct: 250 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANH 309
Query: 181 DIEQFVEIVEDFSKDSRLVDIIKKYPLDK---MIVFTETKKKADKICGLLRLSGFNSGSM 351
+I Q V++ + KD +L+ ++++ +K I+F ETK++ D + +R G+ + +
Sbjct: 310 NILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCI 369
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDKSQ +R+++L FR+ IL+ATDVASRGLDV+D+K VINYD+PN EDY+HRIGR
Sbjct: 370 HGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGR 429
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVV 639
TARS +G +YTFF +E+A Q +
Sbjct: 430 TARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAI 465
>sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17 (DEAD-box protein 17)
Length = 650
Score = 228 bits (581), Expect = 1e-59
Identities = 111/216 (51%), Positives = 152/216 (70%), Gaps = 3/216 (1%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEV++LA+DFL Y Q+N+G+ +L AN
Sbjct: 250 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANH 309
Query: 181 DIEQFVEIVEDFSKDSRLVDIIKKYPLDK---MIVFTETKKKADKICGLLRLSGFNSGSM 351
+I Q V++ + KD +L+ ++++ +K I+F ETK++ D + +R G+ + +
Sbjct: 310 NILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCI 369
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDKSQ +R+++L FR+ IL+ATDVASRGLDV+D+K VINYD+PN EDY+HRIGR
Sbjct: 370 HGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGR 429
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVV 639
TARS +G +YTFF +E+A Q +
Sbjct: 430 TARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAI 465
>sp|P24782|DBP2_SCHPO Probable ATP-dependent RNA helicase DBP2 (p68-like protein)
Length = 550
Score = 220 bits (561), Expect = 3e-57
Identities = 119/263 (45%), Positives = 166/263 (63%), Gaps = 3/263 (1%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQT+M+SATWPKEVQ+LA+D+L YIQV +GS DL A+
Sbjct: 280 RMLDMGFEPQIRKIVDQIRPDRQTVMFSATWPKEVQRLARDYLNDYIQVTVGSLDLAASH 339
Query: 181 DIEQFVEIVEDFSKDSRL---VDIIKKYPLDKMIVFTETKKKADKICGLLRLSGFNSGSM 351
+I+Q VE+V++ K +RL ++ + K +K+++FT TK+ AD I LR G+ + ++
Sbjct: 340 NIKQIVEVVDNADKRARLGKDIEEVLKDRDNKVLIFTGTKRVADDITRFLRQDGWPALAI 399
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDK+Q +R+++L FR I+VATDVASRG+DV I V NYDFP EDY+HRIGR
Sbjct: 400 HGDKAQDERDWVLNEFRTGKSPIMVATDVASRGIDVKGITHVFNYDFPGNTEDYVHRIGR 459
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVVPDGLYDMAFVPNEKRRKPYNNNPL 711
T R+G +G +YT+F + +AKQ + L +MA + R Y
Sbjct: 460 TGRAGAKGTAYTYFTSDNAKQARELVSILSEAKQDIDPKLEEMARYSSGGRGGNYRRGG- 518
Query: 712 FSNGFYQPNSSLGKSTLAYTSSD 780
+ G ++ G +T S+
Sbjct: 519 YGRGGFRRGGGYGNRNRGFTGSN 541
>sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2
Length = 544
Score = 220 bits (561), Expect = 3e-57
Identities = 117/247 (47%), Positives = 156/247 (63%), Gaps = 5/247 (2%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEVQ+LA+D+L IQV IGS +L A+
Sbjct: 268 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVQQLARDYLNDPIQVQIGSLELAASH 327
Query: 181 DIEQFVEIVEDFSKDSRLV---DIIKKYPLDKMIVFTETKKKADKICGLLRLSGFNSGSM 351
+I Q VE+V +F K RLV D + K+++F TK+ D+I LR G+ + ++
Sbjct: 328 NITQLVEVVSEFEKRDRLVKHLDTASQDKESKILIFASTKRTCDEITSYLRQDGWPALAI 387
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDK Q++R+++L FR + I+VATDVA+RG+DV I V+NYD P EDY+HRIGR
Sbjct: 388 HGDKDQRERDWVLNEFRTGNSPIMVATDVAARGIDVKGINFVVNYDMPGNIEDYVHRIGR 447
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVVPDGL--YDMAFVPNEKRRKPYNNN 705
T R+G G + +FF M +AKQ +P+ L YD R+P +
Sbjct: 448 TGRAGATGTAISFFTEDNKSLGASLISIMREAKQNIPEELMKYD---------RRPRGPH 498
Query: 706 PLFSNGF 726
P + G+
Sbjct: 499 PRYGGGY 505
>sp|Q6C4D4|DBP2_YARLI Probable ATP-dependent RNA helicase DBP2
Length = 552
Score = 219 bits (558), Expect = 7e-57
Identities = 113/223 (50%), Positives = 149/223 (66%), Gaps = 3/223 (1%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEVQ+LA D+L IQVNIGS +L A+
Sbjct: 274 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVQRLAHDYLKDQIQVNIGSLELSASH 333
Query: 181 DIEQFVEIVEDFSKDSRLV---DIIKKYPLDKMIVFTETKKKADKICGLLRLSGFNSGSM 351
+I Q VE+ ++ K RLV + + + K ++FT TK+ AD I LR G+ + ++
Sbjct: 334 NITQVVEVCTEYEKRDRLVKHLETVMENKESKCLIFTGTKRVADDITKFLRQDGWPALAI 393
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDK Q++R+++L FR I+VATDVASRG+DV I VINYD+P+ EDY+HRIGR
Sbjct: 394 HGDKQQQERDWVLNEFRQGKSPIMVATDVASRGIDVKGINFVINYDYPSNSEDYVHRIGR 453
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVVPDGLYDM 660
T R+G +G +YT+F + +AKQ + L +M
Sbjct: 454 TGRAGTKGTAYTYFTEDNRKQARDLLVILREAKQHIDPKLEEM 496
>sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2
Length = 554
Score = 215 bits (547), Expect = 1e-55
Identities = 117/246 (47%), Positives = 152/246 (61%), Gaps = 5/246 (2%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEV++LA D+L IQV IGS +L A+
Sbjct: 271 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLASDYLHDPIQVQIGSLELSASH 330
Query: 181 DIEQFVEIVEDFSKDSRLVDIIKKYPLD---KMIVFTETKKKADKICGLLRLSGFNSGSM 351
I Q VE++ DF K RL ++ D K+I+F TK+ D+I LR G+ + ++
Sbjct: 331 TITQIVEVLTDFEKRDRLAKHLETASQDQDSKIIIFASTKRTCDEITSYLRTEGWPALAI 390
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDK+Q +R+++L FR+ I+VATDVA+RG+DV I VINYD P EDY+HRIGR
Sbjct: 391 HGDKAQNERDWVLAEFRSGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGR 450
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVVPDGL--YDMAFVPNEKRRKPYNNN 705
T R+G G + +FF M +AKQ +P+ L YD R Y +
Sbjct: 451 TGRAGSTGTAISFFTEGNKSLGAALIKIMREAKQDIPEELRRYD---------RGQYGQH 501
Query: 706 PLFSNG 723
P + G
Sbjct: 502 PRYGGG 507
>sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DBP2 (p68-like protein)
Length = 546
Score = 213 bits (541), Expect = 6e-55
Identities = 111/220 (50%), Positives = 142/220 (64%), Gaps = 3/220 (1%)
Frame = +1
Query: 1 RMLDMGFEPQIRKIFSQIRYDRQTLMWSATWPKEVQKLAQDFLGKYIQVNIGSRDLHANP 180
RMLDMGFEPQIRKI QIR DRQTLMWSATWPKEV++LA D+L IQV +GS +L A+
Sbjct: 271 RMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASH 330
Query: 181 DIEQFVEIVEDFSKDSRLVDIIKKYPLD---KMIVFTETKKKADKICGLLRLSGFNSGSM 351
+I Q VE+V DF K RL ++ D K ++F TK+ D I LR G+ + ++
Sbjct: 331 NITQIVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDITKYLREDGWPALAI 390
Query: 352 HGDKSQKDREYILQGFRNKSLNILVATDVASRGLDVDDIKIVINYDFPNQFEDYIHRIGR 531
HGDK Q++R+++LQ FRN I+VATDVA+RG+DV I VINYD P EDY+HRIGR
Sbjct: 391 HGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGR 450
Query: 532 TARSGKRGMSYTFFNRXXXXXXXXXXXXMEDAKQVVPDGL 651
T R+G G + +FF M +A Q +P L
Sbjct: 451 TGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPEL 490
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,959,210
Number of Sequences: 369166
Number of extensions: 1749559
Number of successful extensions: 5241
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4929
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5089
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7357347200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)