Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_O22
(664 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P08928|LAM0_DROME Lamin Dm0 75 1e-13
sp|P14732|LAM2_CHICK Lamin B2 65 2e-10
sp|P09010|LAML1_XENLA Lamin L(I) 63 8e-10
sp|P11516|LAMC_MOUSE Lamins C and C2 62 2e-09
sp|P48678|LAMA_MOUSE Lamin A 62 2e-09
sp|P13648|LAMA_CHICK Lamin A 61 2e-09
sp|P48679|LAMA_RAT Lamin A 61 2e-09
sp|Q03252|LAM2_HUMAN Lamin B2 61 3e-09
sp|P21910|LAML2_XENLA Lamin L(II) 60 5e-09
sp|P02545|LAMA_HUMAN Lamin A/C (70 kDa lamin) 60 5e-09
>sp|P08928|LAM0_DROME Lamin Dm0
Length = 622
Score = 75.5 bits (184), Expect = 1e-13
Identities = 38/114 (33%), Positives = 65/114 (57%), Gaps = 6/114 (5%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTLRYTADKQ--ETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPT 264
V L N +++ IGGW L+ +++ TTYKFH ++ ++ TVWS+D+ +H PP+
Sbjct: 485 VRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPS 544
Query: 265 DLVMKGQRFFSGVNIKMSLVNSDNQEEASCS----VVKDHTRTSVYNYNRKIAS 414
LVMK Q++ S N + L+NS+ + A+ +V HT +S + R + +
Sbjct: 545 SLVMKSQKWVSADNTRTILLNSEGEAVANLDRIKRIVSQHTSSSRLSRRRSVTA 598
>sp|P14732|LAM2_CHICK Lamin B2
Length = 600
Score = 64.7 bits (156), Expect = 2e-10
Identities = 37/94 (39%), Positives = 55/94 (58%), Gaps = 2/94 (2%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V+L N ++KD +G W L R D +E YKF ++A T+W +D+ +H+PP+
Sbjct: 469 VQLKNNSEKDQSLGNWRLKRQIGDGEEIAYKFTPKYVLRAGQTVTIWGADAGVSHSPPSV 528
Query: 268 LVMKGQ-RFFSGVNIKMSLVNSDNQEEASCSVVK 366
LV K Q + +G NI+ LVNSD +E A +V K
Sbjct: 529 LVWKNQGSWGTGGNIRTYLVNSDGEEVAVRTVTK 562
>sp|P09010|LAML1_XENLA Lamin L(I)
Length = 583
Score = 62.8 bits (151), Expect = 8e-10
Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTLRYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTDL 270
+ L N ++KD +GGW L T + +KF +KA+ T+W++D+ +PP+DL
Sbjct: 453 IRLKNNSEKDHPLGGWELTRTIGEASVNFKFTSRYVLKAEQTVTIWAADAGVKASPPSDL 512
Query: 271 VMKGQRFF-SGVNIKMSLVNSDNQEEASCSVVKDHTRTSVYNYNRKIASRSVRTGEE 438
+ K Q + +G ++K +L NS +E A RT++Y N I GEE
Sbjct: 513 IWKNQNSWGTGEDVKATLKNSQGEEVAQ--------RTTIYTTN--IPEEEFEEGEE 559
>sp|P11516|LAMC_MOUSE Lamins C and C2
Length = 574
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTLR-YTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V L N +++D +G W +R D TY+F +KA T+W+S + TH+PPTD
Sbjct: 452 VRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTD 511
Query: 268 LVMKGQRFFS-GVNIKMSLVNSDNQEEASCSVVKDHT 375
LV K Q + G +++ +L+NS +E A +V+ T
Sbjct: 512 LVWKAQNTWGCGSSLRTALINSTGEEVAMRKLVRSLT 548
>sp|P48678|LAMA_MOUSE Lamin A
Length = 665
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/97 (35%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTLR-YTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V L N +++D +G W +R D TY+F +KA T+W+S + TH+PPTD
Sbjct: 452 VRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTD 511
Query: 268 LVMKGQRFFS-GVNIKMSLVNSDNQEEASCSVVKDHT 375
LV K Q + G +++ +L+NS +E A +V+ T
Sbjct: 512 LVWKAQNTWGCGSSLRTALINSTGEEVAMRKLVRSLT 548
>sp|P13648|LAMA_CHICK Lamin A
Length = 657
Score = 61.2 bits (147), Expect = 2e-09
Identities = 32/94 (34%), Positives = 55/94 (58%), Gaps = 2/94 (2%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V L N +++D +G W + R D TY+F +KA T+W+S + TH+PP+D
Sbjct: 453 VRLRNKSNEDQALGNWQVKRQNGDDPPLTYRFPPKFTLKAGQAVTIWASGAGATHSPPSD 512
Query: 268 LVMKGQRFF-SGVNIKMSLVNSDNQEEASCSVVK 366
+V K Q + SG +++ +L+NS+ +E A +V+
Sbjct: 513 VVWKAQSSWGSGDSLRTALINSNGEEVAMRKLVR 546
>sp|P48679|LAMA_RAT Lamin A
Length = 665
Score = 61.2 bits (147), Expect = 2e-09
Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V L N +++D +G W + R D TY+F +KA T+W+S + TH+PPTD
Sbjct: 452 VRLRNKSNEDQSMGNWQIKRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTD 511
Query: 268 LVMKGQRFFS-GVNIKMSLVNSDNQEEASCSVVKDHT 375
LV K Q + G +++ +L+N+ +E A +V+ T
Sbjct: 512 LVWKAQNTWGCGTSLRTALINATGEEVAMRKLVRSLT 548
>sp|Q03252|LAM2_HUMAN Lamin B2
Length = 600
Score = 60.8 bits (146), Expect = 3e-09
Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V+L N +DKD +G W + R + +E YKF ++A TVW++ + H+PP+
Sbjct: 466 VQLKNNSDKDQSLGNWRIKRQVLEGEEIAYKFTPKYILRAGQMVTVWAAGAGVAHSPPST 525
Query: 268 LVMKGQRFF-SGVNIKMSLVNSDNQEEASCSVVKDHTRTSVYNYNRKIASRSVRTGEE 438
LV KGQ + +G + + LVN+D +E A +V K N N + GEE
Sbjct: 526 LVWKGQSSWGTGESFRTVLVNADGEEVAMRTVKKSSVMRE--NENGEEEEEEAEFGEE 581
>sp|P21910|LAML2_XENLA Lamin L(II)
Length = 623
Score = 60.1 bits (144), Expect = 5e-09
Identities = 36/98 (36%), Positives = 55/98 (56%), Gaps = 2/98 (2%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V L N +DKD +G W L R +++E YKF +KA ++S+D+ H+PP+
Sbjct: 492 VHLKNNSDKDQSLGNWRLKRKIGEEEEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSI 551
Query: 268 LVMKGQRFF-SGVNIKMSLVNSDNQEEASCSVVKDHTR 378
LV K Q + +G NI+ LVN++ +E A +V K R
Sbjct: 552 LVWKNQSSWGTGSNIRTYLVNTEEEEVAVRTVTKSVLR 589
>sp|P02545|LAMA_HUMAN Lamin A/C (70 kDa lamin)
Length = 664
Score = 60.1 bits (144), Expect = 5e-09
Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Frame = +1
Query: 91 VELINLTDKDLCIGGWTL-RYTADKQETTYKFHHNLHVKAKTDCTVWSSDSNETHNPPTD 267
V L N +++D +G W + R D TY+F +KA T+W++ + TH+PPTD
Sbjct: 452 VRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTD 511
Query: 268 LVMKGQRFFS-GVNIKMSLVNSDNQEEASCSVVKDHT 375
LV K Q + G +++ +L+NS +E A +V+ T
Sbjct: 512 LVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVT 548
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,461,607
Number of Sequences: 369166
Number of extensions: 1379019
Number of successful extensions: 3098
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3010
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3088
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5560129980
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)