Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_O20
(845 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BRQ0|PYGO2_HUMAN Pygopus homolog 2 57 6e-08
sp|Q9V9W8|PYGO_DROME Pygopus protein (Gammy legs protein) 57 6e-08
sp|Q9Y3Y4|PYGO1_HUMAN Pygopus homolog 1 51 4e-06
sp|Q9D0P5|PYGO1_MOUSE Pygopus homolog 1 51 4e-06
sp|P20659|TRX_DROME Trithorax protein 47 5e-05
sp|Q24742|TRX_DROVI Trithorax protein 46 1e-04
sp|Q9UMN6|MLL4_HUMAN Myeloid/lymphoid or mixed-lineage leuk... 36 0.15
sp|Q9ULU4|PKCB1_HUMAN Protein kinase C binding protein 1 (R... 35 0.34
sp|P29375|JAD1A_HUMAN Jumonji/ARID domain-containing protei... 34 0.58
sp|Q9ES18|FOXJ2_MOUSE Forkhead box protein J2 (Fork head ho... 33 1.3
>sp|Q9BRQ0|PYGO2_HUMAN Pygopus homolog 2
Length = 406
Score = 57.0 bits (136), Expect = 6e-08
Identities = 33/98 (33%), Positives = 44/98 (44%)
Frame = +3
Query: 543 SSYVPAGHMMAGNIPVHGPQPGIPPAMINQPITSDRMQIIQVCAQCQKEIVPSNMQFEPI 722
+S P G G+ GPQP PP ++ C C+ E+ N + I
Sbjct: 306 NSLAPPGKAGGGS----GPQP--PPGLVYP------------CGACRSEV---NDDQDAI 344
Query: 723 QCGYSCGHWYHRSCTGLTYEAYSMLRSEPHAEWICKNC 836
C SC W+HR CTG+T AY +L +E A W C C
Sbjct: 345 LCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLC 382
>sp|Q9V9W8|PYGO_DROME Pygopus protein (Gammy legs protein)
Length = 815
Score = 57.0 bits (136), Expect = 6e-08
Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 32/154 (20%)
Frame = +3
Query: 480 LGGNIHPEMM--HLMPNYHF----------------GPISSYVPAGHM-MAGNIPVHGPQ 602
+ G HP M H P++H GP+ P G+M G P+ GP
Sbjct: 655 MNGPPHPHMSPHHGHPHHHHNPMGGPGPNMFGGGGGGPMGPGGPMGNMGPMGGGPMGGPM 714
Query: 603 PGIPPAMI---------NQPIT----SDRMQIIQVCAQCQKEIVPSNMQFEPIQCGYSCG 743
P M QP+ + I C C KE+ N E + C C
Sbjct: 715 GVGPKPMTMGGGKMYPPGQPMVFNPQNPNAPPIYPCGMCHKEV---NDNDEAVFCESGCN 771
Query: 744 HWYHRSCTGLTYEAYSMLRSEPHAEWICKNCENS 845
++HR+C GLT A+ ML E AEW C C +S
Sbjct: 772 FFFHRTCVGLTEAAFQMLNKEVFAEWCCDKCVSS 805
>sp|Q9Y3Y4|PYGO1_HUMAN Pygopus homolog 1
Length = 419
Score = 51.2 bits (121), Expect = 4e-06
Identities = 23/56 (41%), Positives = 29/56 (51%)
Frame = +3
Query: 669 CAQCQKEIVPSNMQFEPIQCGYSCGHWYHRSCTGLTYEAYSMLRSEPHAEWICKNC 836
C C E+ N + I C SC W+HR CTG+T AY +L +E A W C C
Sbjct: 343 CGICTNEV---NDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTC 395
>sp|Q9D0P5|PYGO1_MOUSE Pygopus homolog 1
Length = 417
Score = 51.2 bits (121), Expect = 4e-06
Identities = 23/56 (41%), Positives = 29/56 (51%)
Frame = +3
Query: 669 CAQCQKEIVPSNMQFEPIQCGYSCGHWYHRSCTGLTYEAYSMLRSEPHAEWICKNC 836
C C E+ N + I C SC W+HR CTG+T AY +L +E A W C C
Sbjct: 341 CGICTNEV---NDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTC 393
>sp|P20659|TRX_DROME Trithorax protein
Length = 3726
Score = 47.4 bits (111), Expect = 5e-05
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +3
Query: 669 CAQCQKEIVPSNMQFEPIQCGYSCGHWYHRSCTGLTYEAYSMLRSEPHA-EWICKNC 836
C CQ+ ++ + ++CG CG W H C GL+ E Y++L + P + E+ICK C
Sbjct: 1424 CPICQRCYDDNDFDLKMMECG-DCGQWVHSKCEGLSDEQYNLLSTLPESIEFICKKC 1479
>sp|Q24742|TRX_DROVI Trithorax protein
Length = 3828
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +3
Query: 669 CAQCQKEIVPSNMQFEPIQCGYSCGHWYHRSCTGLTYEAYSMLRSEPHA-EWICKNC 836
C CQK ++ + ++CG C W H C GL+ E Y++L + P + E+ICK C
Sbjct: 1411 CPICQKCYDDNDFDLKMMECG-DCNQWVHSKCEGLSDEQYNLLSTLPESIEFICKKC 1466
>sp|Q9UMN6|MLL4_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax
homolog 2)
Length = 2715
Score = 35.8 bits (81), Expect = 0.15
Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +3
Query: 666 VCAQCQKEIVPSNMQFEPIQCGYSCGHWYHRSCTGLTYEAYSMLRSEPHAE-WICKNC 836
+C +C ++ ++ + + +QC C HW H C GL+ E Y +L P + + C C
Sbjct: 1340 ICTRCYED---NDYESKMMQCA-QCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPC 1393
>sp|Q9ULU4|PKCB1_HUMAN Protein kinase C binding protein 1 (Rack7) (Cutaneous T-cell
lymphoma associated antigen se14-3) (CTCL tumor antigen
se14-3) (Zinc finger MYND domain containing protein 8)
Length = 1186
Score = 34.7 bits (78), Expect = 0.34
Identities = 21/79 (26%), Positives = 30/79 (37%), Gaps = 7/79 (8%)
Frame = +3
Query: 624 INQPITSDRMQIIQ-------VCAQCQKEIVPSNMQFEPIQCGYSCGHWYHRSCTGLTYE 782
+ QP+T+D + ++ C C +E + C C YH C LT
Sbjct: 69 MKQPLTTDPVDVVPQDGRNDFYCWVCHRE--------GQVLCCELCPRVYHAKCLRLT-- 118
Query: 783 AYSMLRSEPHAEWICKNCE 839
SEP +W C CE
Sbjct: 119 ------SEPEGDWFCPECE 131
>sp|P29375|JAD1A_HUMAN Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding
protein 2) (RBBP-2)
Length = 1722
Score = 33.9 bits (76), Expect = 0.58
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +3
Query: 720 IQCGYSCGHWYHRSCTGLTYEAYSMLRSEPHAEWICKNC 836
+QC C W+HR C G++ E M +E ++IC NC
Sbjct: 1658 VQCDGGCDEWFHRVCVGVSPE---MAENE---DYICINC 1690
>sp|Q9ES18|FOXJ2_MOUSE Forkhead box protein J2 (Fork head homologous X)
Length = 565
Score = 32.7 bits (73), Expect = 1.3
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Frame = +3
Query: 495 HPEMMHLMPNYHFGPISSYVPAGHMMAG-NIPVHG--PQPGIPPAMINQPITSD 647
HP+ HL P GP Y + AG N P H P+P +PP N+ IT D
Sbjct: 509 HPQASHLYP----GPAPMYPISTQDSAGYNRPAHHMVPRPPVPPPGANEEITDD 558
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,211,948
Number of Sequences: 369166
Number of extensions: 2054721
Number of successful extensions: 6245
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5899
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6241
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)