Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_O17
(805 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A 240 4e-63
sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A 239 5e-63
sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A 238 2e-62
sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B 238 2e-62
sp|P05714|RAB4A_RAT Ras-related protein Rab-4A 235 1e-61
sp|P51146|RAB4B_RAT Ras-related protein Rab-4B >gi|46577105... 231 2e-60
sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B >gi|465776... 230 3e-60
sp|Q9GP33|RAB4A_ECHMU Probable Ras-related protein Rab-4A 212 1e-54
sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14 203 4e-52
sp|P61107|RAB14_RAT Ras-related protein Rab-14 >gi|46577643... 203 4e-52
>sp|P20338|RAB4A_HUMAN Ras-related protein Rab-4A
Length = 213
Score = 240 bits (612), Expect = 4e-63
Identities = 126/227 (55%), Positives = 164/227 (72%), Gaps = 1/227 (0%)
Frame = +1
Query: 37 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQ 216
M+E Y+FLFKFL+IGNAG GKSC+LH FIE+K K++S HTIGVEF SKII V + +KLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQ 60
Query: 217 IWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVG 396
IWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120
Query: 397 NKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESND 576
NKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F++CAR +++K ES +
Sbjct: 121 NKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGE 177
Query: 577 LSDNIAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARA-NSSNCQC 714
L + S GD R R SP RA+A N+ C C
Sbjct: 178 LDPE--RMGSGIQYGDAALRQLR---SP------RRAQAPNAQECGC 213
>sp|Q6PHI9|RAB4A_BRARE Ras-related protein Rab-4A
Length = 213
Score = 239 bits (611), Expect = 5e-63
Identities = 113/181 (62%), Positives = 149/181 (82%)
Frame = +1
Query: 37 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQ 216
M+E Y+FLFKFL+IGNAG GKSC+LH FIE++ K++S HTIGVEF SKII V N+ +KLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIISVVNKFVKLQ 60
Query: 217 IWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVG 396
IWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120
Query: 397 NKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESND 576
NKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F++CAR +++K ES +
Sbjct: 121 NKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGE 177
Query: 577 L 579
L
Sbjct: 178 L 178
>sp|P56371|RAB4A_MOUSE Ras-related protein Rab-4A
Length = 213
Score = 238 bits (606), Expect = 2e-62
Identities = 112/181 (61%), Positives = 148/181 (81%)
Frame = +1
Query: 37 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQ 216
M+E Y+FLFKFL+IGNAG GKSC+LH FIE+K K++S HTIG+EF SKII V + +KLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGMEFGSKIINVGGKYVKLQ 60
Query: 217 IWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVG 396
IWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCG 120
Query: 397 NKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESND 576
NKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F++CAR +++K ES +
Sbjct: 121 NKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGE 177
Query: 577 L 579
L
Sbjct: 178 L 178
>sp|Q68EK7|RAB4B_BRARE Ras-related protein Rab-4B
Length = 213
Score = 238 bits (606), Expect = 2e-62
Identities = 110/181 (60%), Positives = 149/181 (82%)
Frame = +1
Query: 37 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQ 216
M+E Y+FLFKFL+IG+AG GKSC+LH FIE K K++S HTIGVEF S+++ V +T+KLQ
Sbjct: 1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
Query: 217 IWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVG 396
IWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++NA+ NWL+DA++LA N+ IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCG 120
Query: 397 NKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESND 576
NKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F++CAR++ +K ES +
Sbjct: 121 NKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSIPNKIESGE 177
Query: 577 L 579
L
Sbjct: 178 L 178
>sp|P05714|RAB4A_RAT Ras-related protein Rab-4A
Length = 213
Score = 235 bits (599), Expect = 1e-61
Identities = 111/181 (61%), Positives = 146/181 (80%)
Frame = +1
Query: 37 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQ 216
M+E Y+FLFKFL+IGNAG GKSC+LH FIE+K K++S HTIGVEF KII V + +KLQ
Sbjct: 1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGQKIINVGGKYVKLQ 60
Query: 217 IWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVG 396
IWDTAGQERFRSV SYYRGA+GAL+VYDIT+R+++NA+ NWL+DA+ LA N+ IL G
Sbjct: 61 IWDTAGQERFRSVTTSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCG 120
Query: 397 NKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESND 576
NKKDL A REV++ EA F++ENE+ F ETSA+ GE++++ F++CAR +++K ES +
Sbjct: 121 NKKDL---DADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGE 177
Query: 577 L 579
L
Sbjct: 178 L 178
>sp|P51146|RAB4B_RAT Ras-related protein Rab-4B
sp|Q91ZR1|RAB4B_MOUSE Ras-related protein Rab-4B
Length = 213
Score = 231 bits (589), Expect = 2e-60
Identities = 111/200 (55%), Positives = 152/200 (76%)
Frame = +1
Query: 37 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQ 216
M E Y+FLFKFL+IG+AG GKSC+LH FIE K K++S HTIGVEF S+++ V +T+KLQ
Sbjct: 1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
Query: 217 IWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVG 396
IWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++N++ WL+DA++LA N+ IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG 120
Query: 397 NKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESND 576
NKKDL REV++ EA F++ENE+ F ETSA+ GE++++ F++CAR +++K +S +
Sbjct: 121 NKKDL---DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGE 177
Query: 577 LSDNIAQNSSSQNSGDIRKR 636
L + S GDI R
Sbjct: 178 LDPE--RMGSGIQYGDISLR 195
>sp|P61018|RAB4B_HUMAN Ras-related protein Rab-4B
sp|P61017|RAB4B_CANFA Ras-related protein Rab-4B
Length = 213
Score = 230 bits (587), Expect = 3e-60
Identities = 106/181 (58%), Positives = 146/181 (80%)
Frame = +1
Query: 37 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQ 216
M E Y+FLFKFL+IG+AG GKSC+LH FIE K K++S HTIGVEF S+++ V +T+KLQ
Sbjct: 1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQ 60
Query: 217 IWDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVG 396
IWDTAGQERFRSV RSYYRGA+GAL+VYDIT+R+++N++ WL+DA++LA N+ IL G
Sbjct: 61 IWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCG 120
Query: 397 NKKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESND 576
NKKDL REV++ EA F++ENE+ F ETSA+ GE++++ F++CAR +++K +S +
Sbjct: 121 NKKDL---DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGE 177
Query: 577 L 579
L
Sbjct: 178 L 178
>sp|Q9GP33|RAB4A_ECHMU Probable Ras-related protein Rab-4A
Length = 223
Score = 212 bits (539), Expect = 1e-54
Identities = 111/226 (49%), Positives = 150/226 (66%), Gaps = 1/226 (0%)
Frame = +1
Query: 40 NEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQI 219
++++++LFKFLIIGNAG GK+CIL + E+K N+ HTIG EF S++I V+ +K+QI
Sbjct: 3 SDRFDYLFKFLIIGNAGTGKTCILRRYTERKFFPNTQHTIGAEFGSRVISVDGTHVKIQI 62
Query: 220 WDTAGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGN 399
WDTAGQERFRS+ARSYY A G L+VYDITNR SF AV WL DA+ LA + ILVGN
Sbjct: 63 WDTAGQERFRSMARSYYHDAVGTLLVYDITNRTSFGAVEQWLGDARHLATPGVVVILVGN 122
Query: 400 KKDLADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDL 579
KKDL D +V++ EA F++EN +QF ETSA+ GE+IDD F C R ++SK +S +L
Sbjct: 123 KKDLRD--TDGQVTHWEANTFAQENGLQFIETSALTGENIDDAFTSCVRVLLSKVKSGEL 180
Query: 580 -SDNIAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARANSSNCQC 714
+D + S+ Q+ + S + + S A A+S C C
Sbjct: 181 GADRLLVGSNKQHLQAVNL---TASATSVSASQSSAATAHSDTCLC 223
>sp|Q91V41|RAB14_MOUSE Ras-related protein Rab-14
Length = 215
Score = 203 bits (517), Expect = 4e-52
Identities = 101/222 (45%), Positives = 143/222 (64%)
Frame = +1
Query: 49 YEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQIWDT 228
Y ++FK++IIG+ GVGKSC+LH F E+K + HTIGVEF ++II+V+ + IKLQIWDT
Sbjct: 8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDT 67
Query: 229 AGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKD 408
AGQERFR+V RSYYRGA+GAL+VYDIT R ++N + +WL+DA++L N IL+GNK
Sbjct: 68 AGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNK-- 125
Query: 409 LADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDLSDN 588
AD +A R+V+Y EA+ F++EN + F E SA GE+++D F+E A+ + + L N
Sbjct: 126 -ADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLN 184
Query: 589 IAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARANSSNCQC 714
A++ +P GG S + C C
Sbjct: 185 AAESGVQHK-----------PSAPQGGRLTSEPQPQREGCGC 215
>sp|P61107|RAB14_RAT Ras-related protein Rab-14
sp|P61106|RAB14_HUMAN Ras-related protein Rab-14
Length = 215
Score = 203 bits (517), Expect = 4e-52
Identities = 101/222 (45%), Positives = 143/222 (64%)
Frame = +1
Query: 49 YEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQIWDT 228
Y ++FK++IIG+ GVGKSC+LH F E+K + HTIGVEF ++II+V+ + IKLQIWDT
Sbjct: 8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDT 67
Query: 229 AGQERFRSVARSYYRGASGALVVYDITNRDSFNAVINWLSDAKSLAGTNLSAILVGNKKD 408
AGQERFR+V RSYYRGA+GAL+VYDIT R ++N + +WL+DA++L N IL+GNK
Sbjct: 68 AGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNK-- 125
Query: 409 LADYKASREVSYAEAEAFSKENEMQFYETSAVNGEHIDDVFIECARAVVSKWESNDLSDN 588
AD +A R+V+Y EA+ F++EN + F E SA GE+++D F+E A+ + + L N
Sbjct: 126 -ADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLN 184
Query: 589 IAQNSSSQNSGDIRKRWNRLSGSPAGGIRLSRARANSSNCQC 714
A++ +P GG S + C C
Sbjct: 185 AAESGVQHK-----------PSAPQGGRLTSEPQPQREGCGC 215
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,029,238
Number of Sequences: 369166
Number of extensions: 1865112
Number of successful extensions: 6532
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5950
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6129
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)