Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_O08
(331 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) 42 6e-04
sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2) 40 0.001
sp|P06882|THYG_RAT Thyroglobulin precursor 40 0.001
sp|P01267|THYG_BOVIN Thyroglobulin precursor 39 0.003
sp|P04233|HG2A_HUMAN HLA class II histocompatibility antige... 39 0.004
sp|P01266|THYG_HUMAN Thyroglobulin precursor 39 0.004
sp|O08710|THYG_MOUSE Thyroglobulin precursor 38 0.006
sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonect... 37 0.011
sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonect... 37 0.011
sp|P10247|HG2A_RAT H-2 class II histocompatibility antigen,... 37 0.014
>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX)
Length = 844
Score = 41.6 bits (96), Expect = 6e-04
Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Frame = +1
Query: 67 KCARDRNEYKKLKIIGRLF-FCDDYGNYKKVQCLGSV--CYCVDANGKQI 207
KC ++R + K+IG CD+ GNY+ QC GS C+CV+A G++I
Sbjct: 109 KCLKERQQALAKKMIGHYIPQCDEKGNYQPQQCHGSTGHCWCVNAMGEKI 158
Score = 30.0 bits (66), Expect = 1.7
Identities = 17/38 (44%), Positives = 24/38 (63%), Gaps = 3/38 (7%)
Frame = +1
Query: 103 KIIGRLF-FCDDYGNYKKVQCLGSVCY--CVDANGKQI 207
K++GR CD+ GNY+ Q GS Y CV+A G++I
Sbjct: 193 KVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGEEI 230
>sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2)
Length = 1403
Score = 40.4 bits (93), Expect = 0.001
Identities = 16/30 (53%), Positives = 21/30 (70%), Gaps = 2/30 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSV--CYCVDANGKQIP 210
CDD GN+ +QC GS C+CVD NG ++P
Sbjct: 991 CDDQGNFVPLQCHGSTGFCWCVDRNGHEVP 1020
Score = 32.3 bits (72), Expect = 0.34
Identities = 12/29 (41%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCLG--SVCYCVDANGKQI 207
CDD G++ +QC G C+CVD +G+++
Sbjct: 1071 CDDLGHFIPLQCHGKSDFCWCVDKDGREL 1099
>sp|P06882|THYG_RAT Thyroglobulin precursor
Length = 2768
Score = 40.4 bits (93), Expect = 0.001
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 6/54 (11%)
Frame = +1
Query: 67 KCARDRNEYKKL---KIIGRLFF---CDDYGNYKKVQCLGSVCYCVDANGKQIP 210
KC + R + + L + G FF C G + VQC S CYCVDA G+ IP
Sbjct: 661 KCEKQRAQMQNLAGAQPAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIP 714
Score = 34.7 bits (78), Expect = 0.069
Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 2/37 (5%)
Frame = +1
Query: 112 GRLFF--CDDYGNYKKVQCLGSVCYCVDANGKQIPTS 216
GR F C G+Y+ +QC C+CV++ GK++ S
Sbjct: 613 GRFFVPSCTAEGSYEDIQCYAGECWCVNSQGKEVEGS 649
Score = 33.9 bits (76), Expect = 0.12
Identities = 13/32 (40%), Positives = 22/32 (68%), Gaps = 2/32 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCL--GSVCYCVDANGKQIPTS 216
C + G+++ VQC G C+CVD++G ++P S
Sbjct: 53 CSEDGSFQTVQCQNDGQSCWCVDSDGTEVPGS 84
Score = 32.7 bits (73), Expect = 0.26
Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Frame = +1
Query: 127 CDDYGNYKKVQC-LGSVCYCVDANGKQIP 210
C G+Y+ VQC + +C+CVDA G +IP
Sbjct: 320 CHRDGHYQTVQCQMERMCWCVDAQGIEIP 348
Score = 31.6 bits (70), Expect = 0.58
Identities = 15/29 (51%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQC-LGSV-CYCVDANGKQI 207
C D GNY VQC L V C+CVD G ++
Sbjct: 121 CQDSGNYAPVQCDLQQVQCWCVDTEGMEV 149
>sp|P01267|THYG_BOVIN Thyroglobulin precursor
Length = 2769
Score = 39.3 bits (90), Expect = 0.003
Identities = 15/28 (53%), Positives = 17/28 (60%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSVCYCVDANGKQIP 210
C GN+ VQC S CYCVD G+ IP
Sbjct: 686 CTSKGNFLPVQCFNSECYCVDTEGQPIP 713
Score = 36.6 bits (83), Expect = 0.018
Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Frame = +1
Query: 112 GRLFF--CDDYGNYKKVQCLGSVCYCVDANGKQIPTS 216
G LF C G+Y++VQC C+CVDA G+++ S
Sbjct: 612 GSLFVPACTAEGSYEEVQCFAGDCWCVDAQGRELAGS 648
Score = 36.2 bits (82), Expect = 0.024
Identities = 14/32 (43%), Positives = 21/32 (65%), Gaps = 2/32 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSV--CYCVDANGKQIPTS 216
CD +G ++ VQC + C+CVD G+ +PTS
Sbjct: 1031 CDAFGGWEPVQCHAATGHCWCVDGKGEYVPTS 1062
Score = 35.0 bits (79), Expect = 0.053
Identities = 14/32 (43%), Positives = 24/32 (75%), Gaps = 2/32 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCL--GSVCYCVDANGKQIPTS 216
C + G+++ VQC G+ C+CVDA+G+++P S
Sbjct: 52 CAEDGSFQTVQCGKDGASCWCVDADGREVPGS 83
Score = 32.3 bits (72), Expect = 0.34
Identities = 13/29 (44%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Frame = +1
Query: 127 CDDYGNYKKVQCL-GSVCYCVDANGKQIP 210
C G Y+ QC G C+CVD+ G++IP
Sbjct: 319 CHPDGEYQAAQCQQGGPCWCVDSRGQEIP 347
Score = 30.8 bits (68), Expect = 0.99
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQC--LGSVCYCVDANGKQI 207
C D G+Y VQC C+CVDA G ++
Sbjct: 120 CQDSGDYSPVQCDLRRRQCWCVDAEGMEV 148
>sp|P04233|HG2A_HUMAN HLA class II histocompatibility antigen, gamma chain (HLA-DR
antigens associated invariant chain) (Ia
antigen-associated invariant chain) (Ii) (p33) (CD74
antigen)
Length = 296
Score = 38.9 bits (89), Expect = 0.004
Identities = 15/32 (46%), Positives = 22/32 (68%), Gaps = 2/32 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSV--CYCVDANGKQIPTS 216
CD+ GNY +QC GS+ C+CV NG ++P +
Sbjct: 232 CDENGNYLPLQCYGSIGYCWCVFPNGTEVPNT 263
>sp|P01266|THYG_HUMAN Thyroglobulin precursor
Length = 2768
Score = 38.9 bits (89), Expect = 0.004
Identities = 15/28 (53%), Positives = 18/28 (64%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSVCYCVDANGKQIP 210
C G++ VQC S CYCVDA G+ IP
Sbjct: 687 CTSEGHFLPVQCFNSECYCVDAEGQAIP 714
Score = 36.2 bits (82), Expect = 0.024
Identities = 16/36 (44%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Frame = +1
Query: 115 RLFF--CDDYGNYKKVQCLGSVCYCVDANGKQIPTS 216
RLF C G+Y+ VQC C+CV++ GK++P S
Sbjct: 614 RLFVPSCTTEGSYEDVQCFSGECWCVNSWGKELPGS 649
Score = 31.6 bits (70), Expect = 0.58
Identities = 14/32 (43%), Positives = 19/32 (59%), Gaps = 2/32 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSV--CYCVDANGKQIPTS 216
CD +G+++ VQC C+CVD G IP S
Sbjct: 1031 CDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGS 1062
Score = 30.0 bits (66), Expect = 1.7
Identities = 12/29 (41%), Positives = 19/29 (65%), Gaps = 2/29 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCL--GSVCYCVDANGKQI 207
C + G+++ VQC G C+CV ANG ++
Sbjct: 52 CAEDGSFQTVQCQNDGRSCWCVGANGSEV 80
Score = 30.0 bits (66), Expect = 1.7
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQC--LGSVCYCVDANGKQI 207
C D G+Y VQC C+CVDA G ++
Sbjct: 120 CQDSGDYAPVQCDVQQVQCWCVDAEGMEV 148
Score = 30.0 bits (66), Expect = 1.7
Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Frame = +1
Query: 127 CDDYGNYKKVQC-LGSVCYCVDANGKQI 207
C G+Y+ VQC C+CVDA GK++
Sbjct: 319 CRRNGDYQAVQCQTEGPCWCVDAQGKEM 346
>sp|O08710|THYG_MOUSE Thyroglobulin precursor
Length = 2766
Score = 38.1 bits (87), Expect = 0.006
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Frame = +1
Query: 67 KCARDRNEYKKL---KIIGRLFF---CDDYGNYKKVQCLGSVCYCVDANGKQIP 210
KC + R + + L + G FF C G + VQC S CYCVD G+ IP
Sbjct: 661 KCEKQRAQMQSLASAQPAGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIP 714
Score = 35.0 bits (79), Expect = 0.053
Identities = 13/32 (40%), Positives = 23/32 (71%), Gaps = 2/32 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCL--GSVCYCVDANGKQIPTS 216
C + G+++ VQC G C+CVD++G+++P S
Sbjct: 53 CSEDGSFQTVQCQNDGQSCWCVDSDGREVPGS 84
Score = 34.7 bits (78), Expect = 0.069
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSVCYCVDANGKQIPTS 216
C G+Y+ +QC C+CVD+ GK++ S
Sbjct: 620 CTAGGSYEDIQCYAGECWCVDSRGKELDGS 649
Score = 33.5 bits (75), Expect = 0.15
Identities = 13/29 (44%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Frame = +1
Query: 127 CDDYGNYKKVQC-LGSVCYCVDANGKQIP 210
C G+Y+ VQC +C+CVDA G+++P
Sbjct: 320 CHRDGHYQTVQCQTEGMCWCVDAQGREVP 348
Score = 31.2 bits (69), Expect = 0.76
Identities = 15/29 (51%), Positives = 18/29 (62%), Gaps = 2/29 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQC-LGSV-CYCVDANGKQI 207
C D GNY VQC L V C+CVD G ++
Sbjct: 121 CQDSGNYAPVQCDLQRVQCWCVDTEGMEV 149
>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 37.4 bits (85), Expect = 0.011
Identities = 23/54 (42%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Frame = +1
Query: 55 QTEGKCARDRNEYKKLKIIGRLF-FCDDYGNYKKVQCLGSV--CYCVDANGKQI 207
QTE + R KKL +G+ CD+ G YK QC GSV C+CVD G ++
Sbjct: 318 QTELSNIQKRQGVKKL--LGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEV 369
>sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 37.4 bits (85), Expect = 0.011
Identities = 23/54 (42%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Frame = +1
Query: 55 QTEGKCARDRNEYKKLKIIGRLF-FCDDYGNYKKVQCLGSV--CYCVDANGKQI 207
QTE + R KKL +G+ CD+ G YK QC GSV C+CVD G ++
Sbjct: 318 QTELSNIQKRQGVKKL--LGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEV 369
>sp|P10247|HG2A_RAT H-2 class II histocompatibility antigen, gamma chain (MHC class II
associated invariant chain) (Ia antigen-associated
invariant chain) (Ii) (CD74 antigen)
Length = 280
Score = 37.0 bits (84), Expect = 0.014
Identities = 15/30 (50%), Positives = 20/30 (66%), Gaps = 2/30 (6%)
Frame = +1
Query: 127 CDDYGNYKKVQCLGSV--CYCVDANGKQIP 210
CD+ GNY +QC GS C+CV NG ++P
Sbjct: 216 CDENGNYMPLQCHGSTGYCWCVFPNGTEVP 245
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,572,335
Number of Sequences: 369166
Number of extensions: 667379
Number of successful extensions: 1580
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1506
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1568
length of database: 68,354,980
effective HSP length: 78
effective length of database: 53,945,650
effective search space used: 1672315150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)