Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_N18
(747 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q62433|NDRG1_MOUSE NDRG1 protein (N-myc downstream regul... 57 4e-08
sp|Q92597|NDRG1_HUMAN NDRG1 protein (N-myc downstream regul... 55 2e-07
sp|Q9UN36|NDRG2_HUMAN NDRG2 protein (Syld709613 protein) 52 1e-06
sp|Q9QYG0|NDRG2_MOUSE NDRG2 protein (Ndr2 protein) 52 2e-06
sp|Q9Z2L9|NDRG4_RAT NDRG4 protein (Brain development-relate... 49 1e-05
sp|Q9ULP0|NDRG4_HUMAN NDRG4 protein (Brain development-rela... 49 2e-05
sp|Q8BTG7|NDRG4_MOUSE NDRG4 protein 48 3e-05
sp|Q9UGV2|NDRG3_HUMAN NDRG3 protein 45 3e-04
sp|Q9QYF9|NDRG3_MOUSE NDRG3 protein (Ndr3 protein) 42 0.002
sp|P03726|VIVD_BPT7 Internal virion protein D 32 2.4
>sp|Q62433|NDRG1_MOUSE NDRG1 protein (N-myc downstream regulated gene 1 protein) (Protein
Ndr1)
Length = 394
Score = 57.4 bits (137), Expect = 4e-08
Identities = 48/202 (23%), Positives = 97/202 (48%), Gaps = 11/202 (5%)
Frame = +2
Query: 5 WKLSTI-GMTSSTENYLVVHRFG---VMNNLQSDEELSTMINNYKKFLRDTFNTKNLHGY 172
W S I G T + + +V H FG + NN++ +++ Y++ + + N NLH +
Sbjct: 175 WAASKISGWTQALPDMVVSHLFGKEEIHNNVE-------VVHTYRQHILNDMNPSNLHLF 227
Query: 173 VTSYMNRSNL-IDKSM------SIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRK 331
+++Y +R +L I++ M +++CP L + G + D V ++ K DP +
Sbjct: 228 ISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAV------VECNSKLDPTKT 281
Query: 332 RHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPTGNRKISMEE 511
++ + + + ++AE+ +YF+QG G + SA R+ + +G+ S+E
Sbjct: 282 TLLKMADCGGLPQI--SQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLE- 338
Query: 512 YDSPKGPSNITYNPRRKYSESE 577
+ S+ + PR + SE
Sbjct: 339 --GTRSRSHTSEGPRSRSHTSE 358
>sp|Q92597|NDRG1_HUMAN NDRG1 protein (N-myc downstream regulated gene 1 protein)
(Differentiation-related gene 1 protein) (DRG1)
(Reducing agents and tunicamycin-responsive protein)
(RTP) (Nickel-specific induction protein Cap43) (Rit42)
Length = 394
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/199 (24%), Positives = 95/199 (47%), Gaps = 8/199 (4%)
Frame = +2
Query: 5 WKLSTI-GMTSSTENYLVVHRFGVMNNLQSDEELSTMINNYKKFLRDTFNTKNLHGYVTS 181
W S I G T + + +V H FG +QS+ E+ ++ Y++ + + N NLH ++ +
Sbjct: 175 WAASKISGWTQALPDMVVSHLFG-KEEMQSNVEV---VHTYRQHIVNDMNPGNLHLFINA 230
Query: 182 YMNRSNL-IDKSM------SIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHI 340
Y +R +L I++ M +++CP L + G + D V ++ K DP + +
Sbjct: 231 YNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAV------VECNSKLDPTKTTLL 284
Query: 341 EFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMSSTVRPTGNRKISMEEYDS 520
+ + + + ++AE+ +YF+QG G + SA R+ + +G+ S+ D
Sbjct: 285 KMADCGGLPQI--SQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGS---SVTSLDG 339
Query: 521 PKGPSNITYNPRRKYSESE 577
+ S+ + R + SE
Sbjct: 340 TRSRSHTSEGTRSRSHTSE 358
>sp|Q9UN36|NDRG2_HUMAN NDRG2 protein (Syld709613 protein)
Length = 371
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/154 (27%), Positives = 73/154 (47%), Gaps = 6/154 (3%)
Frame = +2
Query: 23 GMTSSTENYLVVHRFGVMNNLQSDEELS---TMINNYKKFLRDTFNTKNLHGYVTSYMNR 193
G+TSS ++ H F S EELS +I Y+ + N N+ Y SY NR
Sbjct: 188 GLTSSIPEMILGHLF-------SQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNR 240
Query: 194 SNLIDK---SMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNC 364
+L + +++RCP++ + G A + D V ++ K DP + ++ D+
Sbjct: 241 RDLNFERGGDITLRCPVMLVVGDQAPHEDAV------VECNSKLDPTQTSFLKMA--DSG 292
Query: 365 ANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMS 466
+ + ++ E+ +YFLQG G + S+ R+S
Sbjct: 293 GQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLS 326
>sp|Q9QYG0|NDRG2_MOUSE NDRG2 protein (Ndr2 protein)
Length = 371
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/154 (26%), Positives = 75/154 (48%), Gaps = 6/154 (3%)
Frame = +2
Query: 23 GMTSSTENYLVVHRFGVMNNLQSDEELS---TMINNYKKFLRDTFNTKNLHGYVTSYMNR 193
G+TSS + ++ H F S EELS +I Y+ ++ N +N+ Y SY NR
Sbjct: 188 GLTSSIPDMILGHLF-------SQEELSGNSELIQKYRGIIQHAPNLENIELYWNSYNNR 240
Query: 194 SNLIDK---SMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNC 364
+L + +++CP++ + G A + D V ++ K DP + ++ D+
Sbjct: 241 RDLNFERGGETTLKCPVMLVVGDQAPHEDAV------VECNSKLDPTQTSFLKMA--DSG 292
Query: 365 ANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMS 466
+ + ++ E+ +YFLQG G + S+ R+S
Sbjct: 293 GQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLS 326
>sp|Q9Z2L9|NDRG4_RAT NDRG4 protein (Brain development-related molecule 1)
Length = 352
Score = 48.9 bits (115), Expect = 1e-05
Identities = 35/150 (23%), Positives = 68/150 (45%), Gaps = 10/150 (6%)
Frame = +2
Query: 71 VMNNLQSDEEL---STMINNYKKFLRDTFNTKNLHGYVTSY-------MNRSNLIDKSMS 220
V+++L S EEL + ++ +Y++ + N NL + Y +NR + + +
Sbjct: 165 VLSHLFSQEELVNNTELVQSYRQQISSVVNQANLQLFWNMYNSRRDLDINRPGTVPNAKT 224
Query: 221 IRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNCANVIVERTDQVA 400
+RCP++ + G A D V ++ K DP ++ + V + ++
Sbjct: 225 LRCPVMLVVGDNAPAEDGV------VECNSKLDPTTTTFLKMADSGGLPQVT--QPGKLT 276
Query: 401 ESLQYFLQGQGLVGSAPSRRMSSTVRPTGN 490
E+ +YFLQG G + RR+S P+ +
Sbjct: 277 EAFKYFLQGMGYIAHLKDRRLSGGAVPSAS 306
>sp|Q9ULP0|NDRG4_HUMAN NDRG4 protein (Brain development-related molecule 1) (Vascular
smooth muscle cell associated protein 8) (SMAP-8)
Length = 352
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 10/150 (6%)
Frame = +2
Query: 71 VMNNLQSDEEL---STMINNYKKFLRDTFNTKNLHGYVTSY-------MNRSNLIDKSMS 220
V+++L S EEL + ++ +Y++ + + N NL + Y +NR + + +
Sbjct: 165 VLSHLFSQEELVNNTELVQSYRQQIGNVVNQANLQLFWNMYNSRRDLDINRPGTVPNAKT 224
Query: 221 IRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNCANVIVERTDQVA 400
+RCP++ + G A D V ++ K DP ++ + V + ++
Sbjct: 225 LRCPVMLVVGDNAPAEDGV------VECNSKLDPTTTTFLKMADSGGLPQVT--QPGKLT 276
Query: 401 ESLQYFLQGQGLVGSAPSRRMSSTVRPTGN 490
E+ +YFLQG G + RR+S P+ +
Sbjct: 277 EAFKYFLQGMGYIAYLKDRRLSGGAVPSAS 306
>sp|Q8BTG7|NDRG4_MOUSE NDRG4 protein
Length = 352
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/150 (22%), Positives = 69/150 (46%), Gaps = 10/150 (6%)
Frame = +2
Query: 71 VMNNLQSDEEL---STMINNYKKFLRDTFNTKNLHGYVTSY-------MNRSNLIDKSMS 220
V+++L S EEL + ++ +Y++ + + N NL + Y +NR + + +
Sbjct: 165 VLSHLFSQEELVNNTELVQSYRQQISNVVNQANLQLFWNMYNSRRDLDINRPGTVPNAKT 224
Query: 221 IRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRKRHIEFMEIDNCANVIVERTDQVA 400
+RCP++ + G A + V ++ K DP ++ + V + ++
Sbjct: 225 LRCPVMLVVGDNAPAEEGV------VECNSKLDPTTTTFLKMADSGGLPQVT--QPGKLT 276
Query: 401 ESLQYFLQGQGLVGSAPSRRMSSTVRPTGN 490
E+ +YFLQG G + RR+S P+ +
Sbjct: 277 EAFKYFLQGMGYIAHLKDRRLSGGAVPSAS 306
>sp|Q9UGV2|NDRG3_HUMAN NDRG3 protein
Length = 375
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/165 (22%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Frame = +2
Query: 5 WKLSTI-GMTSSTENYLVVHRFGVMNNLQSDEELSTMINNYKKFLRDTFNTKNLHGYVTS 181
W S + G+T++ + ++ H FG LQ++ +L I Y+ + N NL ++ S
Sbjct: 173 WAASKLSGLTTNVVDIILAHHFG-QEELQANLDL---IQTYRMHIAQDINQDNLQLFLNS 228
Query: 182 YMNRSNLI----------DKSMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRK 331
Y R +L +KS +++C L + G D+ + ++ + +P
Sbjct: 229 YNGRRDLEIERPILGQNDNKSKTLKCSTLLVVG------DNSPAVEAVVECNSRLNPINT 282
Query: 332 RHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMS 466
++ + V+ + ++ E+ +YFLQG G + SA R++
Sbjct: 283 TLLKMADCGGLPQVV--QPGKLTEAFKYFLQGMGYIPSASMTRLA 325
>sp|Q9QYF9|NDRG3_MOUSE NDRG3 protein (Ndr3 protein)
Length = 375
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/165 (21%), Positives = 74/165 (44%), Gaps = 11/165 (6%)
Frame = +2
Query: 5 WKLSTI-GMTSSTENYLVVHRFGVMNNLQSDEELSTMINNYKKFLRDTFNTKNLHGYVTS 181
W S + G T++ + ++ H FG LQ++ +L I Y+ + N +NL ++ S
Sbjct: 173 WAASKLSGFTTNIVDIILAHHFG-QEELQANLDL---IQTYRLHIAQDINQENLQLFLGS 228
Query: 182 YMNRSNLI----------DKSMSIRCPMLFISGSLANYADDVKCLYEDIQGFLKNDPDRK 331
Y R +L ++ +++C L + G D+ + ++ + DP
Sbjct: 229 YNGRRDLEIERPILGQNDNRLKTLKCSTLLVVG------DNSPAVEAVVECNSRLDPINT 282
Query: 332 RHIEFMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSRRMS 466
++ + V+ + ++ E+ +YFLQG G + SA R++
Sbjct: 283 TLLKMADCGGLPQVV--QPGKLTEAFKYFLQGMGYIPSASMTRLA 325
>sp|P03726|VIVD_BPT7 Internal virion protein D
Length = 1318
Score = 31.6 bits (70), Expect = 2.4
Identities = 34/143 (23%), Positives = 60/143 (41%), Gaps = 1/143 (0%)
Frame = +2
Query: 101 LSTMINNYKKFLRDTFNTKNLHGYVTSYMNRSNLIDKSMSIRCPMLFISGSLANYADDVK 280
L M+ +K F + N+K L + Y N + ID ++SI M G A A
Sbjct: 1101 LGKMVMQFKSFTIKSLNSKFLRTFYDGYKN-NRAIDAALSIITSMGLAGGFYAMAA---- 1155
Query: 281 CLYEDIQGFLKNDPDRKRHIE-FMEIDNCANVIVERTDQVAESLQYFLQGQGLVGSAPSR 457
++ + RK ++E ++ A+ + R+ Q+ L G++G S+
Sbjct: 1156 ----HVKAYALPKEKRKEYLERALDPTMIAHAALSRSSQLGAPLAMVDLVGGVLGFESSK 1211
Query: 458 RMSSTVRPTGNRKISMEEYDSPK 526
ST+ P K +++E D K
Sbjct: 1212 MARSTILP----KDTVKERDPNK 1230
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,324,166
Number of Sequences: 369166
Number of extensions: 1451569
Number of successful extensions: 3249
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3169
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3244
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6776504000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)