Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_M19
(487 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O13724|ZPR1_SCHPO Zinc-finger protein zpr1 131 9e-31
sp|Q62384|ZPR1_MOUSE Zinc-finger protein ZPR1 (Zinc finger ... 129 5e-30
sp|P53303|ZPR1_YEAST Zinc-finger protein ZPR1 127 1e-29
sp|O75312|ZPR1_HUMAN Zinc-finger protein ZPR1 (Zinc finger ... 125 7e-29
sp|O16999|ZPR1_CAEEL Zinc-finger protein ZPR1 homolog 119 5e-27
sp|Q57950|Y530_METJA Hypothetical protein MJ0530 47 3e-05
sp|Q6J6I8|BRCA1_GORGO Breast cancer type 1 susceptibility p... 30 2.3
sp|Q8RA70|MUTL_THETN DNA mismatch repair protein mutL 29 6.6
sp|O51777|UVRA_BORBU UvrABC system protein A (UvrA protein)... 29 6.6
sp|P46591|HYR1_CANAL Hyphally regulated protein precursor 29 6.6
>sp|O13724|ZPR1_SCHPO Zinc-finger protein zpr1
Length = 459
Score = 131 bits (329), Expect = 9e-31
Identities = 70/153 (45%), Positives = 102/153 (66%), Gaps = 2/153 (1%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMAD 185
I K R+ITLK+ EDL+RD LKS+TA++KIPEL ++ G+LGGRFTT+EG+L Q+ D
Sbjct: 304 IPPKGRKITLKVMDAEDLSRDILKSETASLKIPELGLDLFPGTLGGRFTTIEGLLAQVYD 363
Query: 186 KLEETNPFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGV--TLIIEDPAGGSYIQDIF 359
+L +TD+ T ++N Q L N+ + + TLI++DP SY+Q+ +
Sbjct: 364 ELYGR----VFSQETDSMTPEQVANWQQFLCNLTAAREGATQFTLILDDPLSQSYLQNYY 419
Query: 360 LPEKDPRLTVEDYERTFEENELLGLNDMVTDEY 458
P+ DP +T+E+YER+F+ NE LGLNDM T+ Y
Sbjct: 420 APDPDPNMTIEEYERSFQVNEELGLNDMKTENY 452
Score = 63.5 bits (153), Expect = 2e-10
Identities = 47/148 (31%), Positives = 82/148 (55%), Gaps = 3/148 (2%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMAD 185
I + +IT +E EDL R +KS A + IPE+++E G L G+ TT+EGIL + D
Sbjct: 83 IQPEGSKITFHVEDKEDLNRTVVKSQEAIVSIPEIQLEI-PGRL-GQLTTIEGILSNVVD 140
Query: 186 KLEETNPFLKGDSQTDTPTEVI--LSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQDIF 359
L + + +S+ ++ ++ ++ I+ ++++ SG T+ ++D G S+I+
Sbjct: 141 DLSK-----EQESRKESAPQLYDQINAFIEKVNSLRSGS-VPFTITVDDITGNSWIE--M 192
Query: 360 LPEKD-PRLTVEDYERTFEENELLGLND 440
P +D R + Y+RT E+N LGL D
Sbjct: 193 KPGRDGDRWSQVSYKRTLEQNTKLGLVD 220
>sp|Q62384|ZPR1_MOUSE Zinc-finger protein ZPR1 (Zinc finger protein 259)
Length = 459
Score = 129 bits (323), Expect = 5e-30
Identities = 70/145 (48%), Positives = 92/145 (63%)
Frame = +3
Query: 24 RITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMADKLEETN 203
RITL I P D+TRD LKS+T +++IPELE E LGG+FTT+EG+L + + L N
Sbjct: 310 RITLHITDPSDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRE-LVTKN 368
Query: 204 PFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQDIFLPEKDPRL 383
PF GDS +E L Q L + GK I+ DPAG SY+Q+++ PE DP +
Sbjct: 369 PFTLGDSSNPDQSEK-LQEFSQKLGQIIEGK-MKAHFIMNDPAGNSYLQNVYAPEDDPEM 426
Query: 384 TVEDYERTFEENELLGLNDMVTDEY 458
VE Y+RTF++NE LGLNDM T+ Y
Sbjct: 427 KVERYKRTFDQNEELGLNDMKTEGY 451
Score = 83.2 bits (204), Expect = 3e-16
Identities = 47/150 (31%), Positives = 80/150 (53%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMAD 185
I ++ R TL + + ED+ R+ +K+D+A +IPEL+ E A S G TTVEG++ +
Sbjct: 96 IQDQGVRYTLTVRSQEDMNREVVKTDSATTRIPELDFEIPAFSQKGALTTVEGLISRAIS 155
Query: 186 KLEETNPFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQDIFLP 365
LE+ P + ++ L + S TL+I+DP+G S++++ P
Sbjct: 156 GLEQDQPTRRAVEGAIAERIDEFIGKLKDLKQMAS----PFTLVIDDPSGNSFVENPHAP 211
Query: 366 EKDPRLTVEDYERTFEENELLGLNDMVTDE 455
+KD L + Y+RT ++ E+LGL +E
Sbjct: 212 QKDNALVITYYDRTPQQAEMLGLQAEAPEE 241
>sp|P53303|ZPR1_YEAST Zinc-finger protein ZPR1
Length = 486
Score = 127 bits (320), Expect = 1e-29
Identities = 67/146 (45%), Positives = 96/146 (65%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMAD 185
I +K RRITL + DL+RD LKS+T +M IPEL ++ + G+LGGRFTT+EG+L Q+ +
Sbjct: 340 IPDKGRRITLYCDDAADLSRDILKSETCSMVIPELHLDIQEGTLGGRFTTLEGLLRQVYE 399
Query: 186 KLEETNPFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQDIFLP 365
+L E+ F + D T+ L +GK T+I+EDP GSYIQ+++ P
Sbjct: 400 EL-ESRIFTQTSDSMDEATKARWVEFFAKLKEAIAGK-VKFTVIMEDPLAGSYIQNVYAP 457
Query: 366 EKDPRLTVEDYERTFEENELLGLNDM 443
+ DP +T+EDYERT E+NE LGL+D+
Sbjct: 458 DPDPNMTIEDYERTKEQNEDLGLSDI 483
Score = 68.6 bits (166), Expect = 8e-12
Identities = 50/146 (34%), Positives = 73/146 (50%), Gaps = 3/146 (2%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMAD 185
I EK R LK+E ED R +KS+TA K EL+IE A G+ TTVEG+L +M D
Sbjct: 99 IQEKGSRYVLKVECREDFNRQVIKSETATCKFVELDIEIPAKR--GQLTTVEGLLSEMID 156
Query: 186 KLEETNPFLKGDSQTDTPTEVILSNLIQSLHNV--GSGKRFGVTLIIEDPAGGSYIQDIF 359
L + K D + + IQ + + +T I++DPAG S+I+ +
Sbjct: 157 DLSQDQEMRK---SIDEALYKKIDDFIQKVKSYINCEPNTIPITFILDDPAGNSWIE--Y 211
Query: 360 LP-EKDPRLTVEDYERTFEENELLGL 434
P E + + Y RT E+N +G+
Sbjct: 212 KPGEPQHKWSHTQYVRTDEQNVQVGI 237
>sp|O75312|ZPR1_HUMAN Zinc-finger protein ZPR1 (Zinc finger protein 259)
Length = 459
Score = 125 bits (313), Expect = 7e-29
Identities = 68/145 (46%), Positives = 91/145 (62%)
Frame = +3
Query: 24 RITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMADKLEETN 203
RITL I D+TRD LKS+T +++IPELE E LGG+FTT+EG+L + + L N
Sbjct: 310 RITLHITDASDMTRDLLKSETCSVEIPELEFELGMAVLGGKFTTLEGLLKDIRE-LVTKN 368
Query: 204 PFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQDIFLPEKDPRL 383
PF GDS TE L Q + + G I++DPAG SY+Q+++ PE DP +
Sbjct: 369 PFTLGDSSNPGQTER-LQEFSQKMDQIIEGN-MKAHFIMDDPAGNSYLQNVYAPEDDPEM 426
Query: 384 TVEDYERTFEENELLGLNDMVTDEY 458
VE Y+RTF++NE LGLNDM T+ Y
Sbjct: 427 KVERYKRTFDQNEELGLNDMKTEGY 451
Score = 90.1 bits (222), Expect = 2e-18
Identities = 52/147 (35%), Positives = 84/147 (57%), Gaps = 2/147 (1%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMAD 185
I ++ R TL + ED+ R+ +K+D+AA +IPEL+ E A S G TTVEG++ +
Sbjct: 96 IQDQGVRYTLSVRALEDMNREVVKTDSAATRIPELDFEIPAFSQKGALTTVEGLITRAIS 155
Query: 186 KLEETNPFLKG--DSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQDIF 359
LE+ P + D+ + E I+ ++ L V S TLII+DP+G S++++
Sbjct: 156 GLEQDQPARRANKDATAERIDEFIVK--LKELKQVAS----PFTLIIDDPSGNSFVENPH 209
Query: 360 LPEKDPRLTVEDYERTFEENELLGLND 440
P+KD L + Y RT ++ E+LGL +
Sbjct: 210 APQKDDALVITHYNRTRQQEEMLGLQE 236
>sp|O16999|ZPR1_CAEEL Zinc-finger protein ZPR1 homolog
Length = 455
Score = 119 bits (297), Expect = 5e-27
Identities = 60/151 (39%), Positives = 95/151 (62%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMAD 185
I ++ R+++K+E DL RD LK+DT A+ IPE+++E +L GRFTT+EG+L +
Sbjct: 292 IRDQGCRMSVKLEKDLDLARDVLKTDTCALSIPEIDLEVGGNALCGRFTTIEGLLTATKE 351
Query: 186 KLEETNPFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQDIFLP 365
+L+ + F GDS T + ++ ++ L ++ R T+I++DP G SY+Q + P
Sbjct: 352 QLDAQSSFFMGDS-AQTGEKSAVTTFLEKLDDI-IALRLPATIILDDPTGCSYVQSLTAP 409
Query: 366 EKDPRLTVEDYERTFEENELLGLNDMVTDEY 458
DPRLT E Y RT+E+N+ LG+NDM + Y
Sbjct: 410 MDDPRLTKEFYTRTYEQNDELGINDMKVENY 440
Score = 75.5 bits (184), Expect = 6e-14
Identities = 51/150 (34%), Positives = 78/150 (52%), Gaps = 5/150 (3%)
Frame = +3
Query: 6 ISEKARRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGIL---HQ 176
+ E I L+++ PEDL R +KS+ A++++PEL++E S G TTVEG+L H+
Sbjct: 73 VQEHGTLIVLRVQKPEDLRRQLVKSEYASIEVPELQLEIPHKSQPGEVTTVEGVLERVHR 132
Query: 177 MADKLEETNPFL--KGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYIQ 350
+ +E L +G SQ D + I S + G+ + TL + DP G YIQ
Sbjct: 133 GLSQDQEKRRLLDPEGASQIDAYLQKITSCM-------ELGETW--TLRLRDPTGNCYIQ 183
Query: 351 DIFLPEKDPRLTVEDYERTFEENELLGLND 440
+ + DPR + Y R +E +LL L D
Sbjct: 184 NPDVRHVDPRCIISHYHRNLDERKLLALAD 213
>sp|Q57950|Y530_METJA Hypothetical protein MJ0530
Length = 198
Score = 46.6 bits (109), Expect = 3e-05
Identities = 34/110 (30%), Positives = 59/110 (53%), Gaps = 1/110 (0%)
Frame = +3
Query: 21 RRITLKIETPEDLTRDFLKSDTAAMKIPELEIETEAGSLG-GRFTTVEGILHQMADKLEE 197
++ LKIE+ DL + ++S +A ++IPEL +E + G L G + VEG+L+++ + L+
Sbjct: 59 KKYILKIESERDLNKRVVRSSSAYIQIPELGVEIKPGPLAEGFVSNVEGVLNRVDNILQT 118
Query: 198 TNPFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTLIIEDPAGGSYI 347
+ + + Q E L + + + GK TLI+ DP G S I
Sbjct: 119 LIRWAETEEQKKKAEE-----LRERIKKLKEGKE-EATLILIDPLGHSAI 162
>sp|Q6J6I8|BRCA1_GORGO Breast cancer type 1 susceptibility protein homolog
Length = 1863
Score = 30.4 bits (67), Expect = 2.3
Identities = 16/60 (26%), Positives = 27/60 (45%)
Frame = +3
Query: 48 PEDLTRDFLKSDTAAMKIPELEIETEAGSLGGRFTTVEGILHQMADKLEETNPFLKGDSQ 227
PE + S T+A+K+P+L++ A S TT H M + + P L ++
Sbjct: 1585 PESAHVGNIPSSTSALKVPQLKVAESAQSPAAAHTTNTAGYHAMEESVSREKPELTASTE 1644
>sp|Q8RA70|MUTL_THETN DNA mismatch repair protein mutL
Length = 590
Score = 28.9 bits (63), Expect = 6.6
Identities = 19/54 (35%), Positives = 24/54 (44%)
Frame = -1
Query: 169 KIPSTVVNLPPSEPASVSISNSGIFIAAVSDFKKSLVKSSGVSIFNVILRAFSE 8
K PST + +SN GI V D K + S SI +VILR F +
Sbjct: 162 KRPSTEAMYVTEVVTRLCLSNPGISFKYVKDKKVQFITSGNGSIEDVILRLFGK 215
>sp|O51777|UVRA_BORBU UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)
Length = 950
Score = 28.9 bits (63), Expect = 6.6
Identities = 22/102 (21%), Positives = 41/102 (40%), Gaps = 12/102 (11%)
Frame = +3
Query: 126 AGSLGGRFTTVEGILHQMADKLEETNPFLKGDSQTDTPTE---------VILSNLIQSLH 278
AG LGG ++ + K T +L G + D P+ ++L + +L
Sbjct: 576 AGILGGEIVAKGALIDILNSKNSLTGQYLSGKFKIDVPSSRRKADKGEILLLGSNKNNLK 635
Query: 279 NVGSGKRFGVTLIIEDPAG---GSYIQDIFLPEKDPRLTVED 395
N+ GV +I +G + + ++ P D RL + +
Sbjct: 636 NIDLSIPLGVFTVITGVSGSGKSTLLNEVLYPALDSRLKLNE 677
>sp|P46591|HYR1_CANAL Hyphally regulated protein precursor
Length = 937
Score = 28.9 bits (63), Expect = 6.6
Identities = 13/42 (30%), Positives = 23/42 (54%)
Frame = +3
Query: 189 LEETNPFLKGDSQTDTPTEVILSNLIQSLHNVGSGKRFGVTL 314
+E T+ F DS++ + SN ++H G+G + G+TL
Sbjct: 213 VEPTHNFYLKDSKSSLIVHAVSSNQTFTVHGFGNGNKLGLTL 254
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,494,605
Number of Sequences: 369166
Number of extensions: 985198
Number of successful extensions: 3007
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2934
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2997
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2921208590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)