Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_025_M15 (297 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P23528|COF1_HUMAN Cofilin-1 (Cofilin, non-muscle isoform... 45 4e-05 sp|P45592|COF1_RAT Cofilin-1 (Cofilin, non-muscle isoform) 45 4e-05 sp|P18760|COF1_MOUSE Cofilin-1 (Cofilin, non-muscle isoform) 45 5e-05 sp|Q9Y281|COF2_HUMAN Cofilin-2 (Cofilin, muscle isoform) 45 7e-05 sp|P45591|COF2_MOUSE Cofilin-2 (Cofilin, muscle isoform) 45 7e-05 sp|P10668|COF1_PIG Cofilin-1 (Cofilin, non-muscle isoform) ... 45 7e-05 sp|P21566|COF2_CHICK Cofilin-2 (Cofilin, muscle isoform) 45 7e-05 sp|P37167|ACTP_ACACA Actophorin 44 9e-05 sp|P60982|DEST_PIG Destrin (Actin-depolymerizing factor) (A... 43 2e-04 sp|P18359|DEST_CHICK Destrin (Actin-depolymerizing factor) ... 43 2e-04
>sp|P23528|COF1_HUMAN Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18) Length = 166 Score = 45.4 bits (106), Expect = 4e-05 Identities = 21/54 (38%), Positives = 34/54 (62%), Gaps = 1/54 (1%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 174 L FI W PE+ + S+MI A+SK I ++ G+K +++AN +E+ D + EK Sbjct: 99 LVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|P45592|COF1_RAT Cofilin-1 (Cofilin, non-muscle isoform) Length = 166 Score = 45.4 bits (106), Expect = 4e-05 Identities = 21/54 (38%), Positives = 34/54 (62%), Gaps = 1/54 (1%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 174 L FI W PE+ + S+MI A+SK I ++ G+K +++AN +E+ D + EK Sbjct: 99 LVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|P18760|COF1_MOUSE Cofilin-1 (Cofilin, non-muscle isoform) Length = 166 Score = 45.1 bits (105), Expect = 5e-05 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 174 L FI W PE + S+MI A+SK I ++ G+K +++AN +E+ D + EK Sbjct: 99 LVFIFWAPENAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|Q9Y281|COF2_HUMAN Cofilin-2 (Cofilin, muscle isoform) Length = 166 Score = 44.7 bits (104), Expect = 7e-05 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEKTASKV 189 L FI W PE+ + S+MI A+SK I + G+K + + N D+I D S + EK V Sbjct: 99 LVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNV 157
>sp|P45591|COF2_MOUSE Cofilin-2 (Cofilin, muscle isoform) Length = 166 Score = 44.7 bits (104), Expect = 7e-05 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEKTASKV 189 L FI W PE+ + S+MI A+SK I + G+K + + N D+I D S + EK V Sbjct: 99 LVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGSV 157
>sp|P10668|COF1_PIG Cofilin-1 (Cofilin, non-muscle isoform) sp|Q6B7M7|COF1_SHEEP Cofilin-1 (Cofilin, non-muscle isoform) Length = 166 Score = 44.7 bits (104), Expect = 7e-05 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEK 174 L FI W PE + S+MI A+SK I ++ G+K +++AN +E+ D + EK Sbjct: 99 LVFIFWAPECAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEK 152
>sp|P21566|COF2_CHICK Cofilin-2 (Cofilin, muscle isoform) Length = 166 Score = 44.7 bits (104), Expect = 7e-05 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEI-DESVIKEKTASKV 189 L FI W PE+ + S+MI A+SK I + G+K + + N D+I D S + EK V Sbjct: 99 LVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNV 157
>sp|P37167|ACTP_ACACA Actophorin Length = 138 Score = 44.3 bits (103), Expect = 9e-05 Identities = 17/58 (29%), Positives = 33/58 (56%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEIDESVIKEKTASKV 189 + FI W P++ I S+M+ ++K I ++VG++ +++A EI E + E+ V Sbjct: 80 ITFILWAPDSAPIKSKMMYTSTKDSIKKKLVGIQVEVQATDAAEISEDAVSERAKKDV 137
>sp|P60982|DEST_PIG Destrin (Actin-depolymerizing factor) (ADF) sp|P60981|DEST_HUMAN Destrin (Actin-depolymerizing factor) (ADF) Length = 165 Score = 43.1 bits (100), Expect = 2e-04 Identities = 19/53 (35%), Positives = 31/53 (58%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEIDESVIKEK 174 L F W PE + S+MI A+SK I + G+K + +AN ++++ + I EK Sbjct: 99 LMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEK 151
>sp|P18359|DEST_CHICK Destrin (Actin-depolymerizing factor) (ADF) Length = 165 Score = 43.1 bits (100), Expect = 2e-04 Identities = 19/53 (35%), Positives = 31/53 (58%) Frame = +1 Query: 16 LAFISWIPETMKINSRMIMAASKSEIATRMVGVKAKIEANSEDEIDESVIKEK 174 L F W PE + S+MI A+SK I + G+K + +AN ++++ + I EK Sbjct: 99 LMFFLWAPEQAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEK 151
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,526,277 Number of Sequences: 369166 Number of extensions: 337888 Number of successful extensions: 908 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 906 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 908 length of database: 68,354,980 effective HSP length: 68 effective length of database: 55,793,000 effective search space used: 1673790000 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)