Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_K07
(601 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein m... 240 2e-63
sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein mem... 239 3e-63
sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein m... 239 3e-63
sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein m... 239 3e-63
sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein m... 190 2e-48
sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 ... 156 4e-38
sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein m... 136 5e-32
sp|Q9HD45|TM9S3_HUMAN Transmembrane 9 superfamily protein m... 136 5e-32
sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein m... 130 3e-30
sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein m... 130 3e-30
>sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein member 2 precursor
Length = 662
Score = 240 bits (612), Expect = 2e-63
Identities = 111/163 (68%), Positives = 127/163 (77%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +YYMFG
Sbjct: 500 PVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFL 559
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y IY+I++F +KL I G+
Sbjct: 560 VFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAIHYFFSKLQITGT 619
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 620 ASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 662
>sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein member 2 precursor
Length = 663
Score = 239 bits (611), Expect = 3e-63
Identities = 110/163 (67%), Positives = 127/163 (77%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +YYMFG
Sbjct: 501 PVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFL 560
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y +Y+I++F +KL I G+
Sbjct: 561 VFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLVYAIHYFFSKLQITGT 620
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 621 ASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 663
>sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein member 2 precursor (p76)
Length = 663
Score = 239 bits (611), Expect = 3e-63
Identities = 110/163 (67%), Positives = 127/163 (77%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +YYMFG
Sbjct: 501 PVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFL 560
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y IY++++F +KL I G+
Sbjct: 561 VFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAVHYFFSKLQITGT 620
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 621 ASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 663
>sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein member 2 precursor
Length = 663
Score = 239 bits (611), Expect = 3e-63
Identities = 110/163 (67%), Positives = 127/163 (77%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
PVRTNQIPRQIP Q YT+ +P I+MGG+LPFGCIFIQLFFILNSIWS +YYMFG
Sbjct: 501 PVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFL 560
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
TCSE TILLCYFHLCAEDY W WRSFLTSG TA+Y IY++++F +KL I G+
Sbjct: 561 VFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAVHYFFSKLQITGT 620
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
ST LYFGYT I++ + FL TGT+GF + FWFV KIYSVVKVD
Sbjct: 621 ASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 663
>sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein member 4
Length = 625
Score = 190 bits (483), Expect = 2e-48
Identities = 85/163 (52%), Positives = 115/163 (70%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
PVRTNQIPRQIP Q Y ILM G+LPFG +FI+LFFI ++IW YY+FG
Sbjct: 463 PVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFL 522
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
+CS+ +I++ YF LCAEDYRWWWR+FL SG +A Y+ +Y+I++F KLDI
Sbjct: 523 VFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEF 582
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
+ LYFGYTA+++ +L+TGT+GF +++ FVRKIY+ VK+D
Sbjct: 583 IPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID 625
>sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 kDa endomembrane protein)
(Pheromone alpha-factor transporter) (Acidic 24 kDa late
endocytic intermediate component)
Length = 667
Score = 156 bits (394), Expect = 4e-38
Identities = 77/164 (46%), Positives = 106/164 (64%), Gaps = 1/164 (0%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
P +TNQI RQIP+Q Y ++IP+ L+ G+ PFG I ++L+FI S+W ++YMFG
Sbjct: 506 PTKTNQIARQIPFQPWYLKTIPATLIAGIFPFGSIAVELYFIYTSLWFNKIFYMFGFLFF 565
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGC-TALYLFIYSIYFFHAKLDIKG 357
T S TIL+ Y LC E+++W WR F+ G ALY+FI+SI F K + G
Sbjct: 566 SFLLLTLTSSLVTILITYHSLCLENWKWQWRGFIIGGAGCALYVFIHSILF--TKFKLGG 623
Query: 358 STSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
T+ LY GY+++I L LVTG++GF+SS FVRKIYS +KVD
Sbjct: 624 FTTIVLYVGYSSVISLLCCLVTGSIGFISSMLFVRKIYSSIKVD 667
>sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein member 3 precursor
Length = 587
Score = 136 bits (342), Expect = 5e-32
Identities = 63/163 (38%), Positives = 95/163 (58%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
P R N +PR IP + + + +GG+LPFG IFI+++FI S W+ +YY++G
Sbjct: 425 PCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMML 484
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
TI+ YF L AEDYRW W SFL++ TA+Y+++YS Y++ K + G
Sbjct: 485 VLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGL 544
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
T YFGY A+ ++ G +G++ + FVRKIY+ VK+D
Sbjct: 545 FQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 587
>sp|Q9HD45|TM9S3_HUMAN Transmembrane 9 superfamily protein member 3 precursor (SM-11044
binding protein) (EP70-P-iso)
Length = 589
Score = 136 bits (342), Expect = 5e-32
Identities = 63/163 (38%), Positives = 95/163 (58%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
P R N +PR IP + + + +GG+LPFG IFI+++FI S W+ +YY++G
Sbjct: 427 PCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMML 486
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
TI+ YF L AEDYRW W SFL++ TA+Y+++YS Y++ K + G
Sbjct: 487 VLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGL 546
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
T YFGY A+ ++ G +G++ + FVRKIY+ VK+D
Sbjct: 547 FQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID 589
>sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein member 1 precursor (hMP70)
Length = 606
Score = 130 bits (327), Expect = 3e-30
Identities = 59/163 (36%), Positives = 96/163 (58%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
P RT I R+IP Q Y ++ + +GG LPF I ++L++I ++W Y ++G
Sbjct: 444 PCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFF 503
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
+ +I L YF L EDYRWWWRS L+ G T L++F+YS++++ + ++ G+
Sbjct: 504 VFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGA 563
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
T +FGY+ + ++ FL+ GT+ F SS F+R IY +K+D
Sbjct: 564 VQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606
>sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein member 1 precursor
Length = 606
Score = 130 bits (327), Expect = 3e-30
Identities = 59/163 (36%), Positives = 96/163 (58%)
Frame = +1
Query: 1 PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIFIQLFFILNSIWSTYVYYMFGXXXX 180
P RT I R+IP Q Y ++ + +GG LPF I ++L++I ++W Y ++G
Sbjct: 444 PCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFF 503
Query: 181 XXXXXXXTCSETTILLCYFHLCAEDYRWWWRSFLTSGCTALYLFIYSIYFFHAKLDIKGS 360
+ +I L YF L EDYRWWWRS L+ G T L++F+YS++++ + ++ G+
Sbjct: 504 VFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGA 563
Query: 361 TSTFLYFGYTAIIIWLSFLVTGTVGFVSSFWFVRKIYSVVKVD 489
T +FGY+ + ++ FL+ GT+ F SS F+R IY +K+D
Sbjct: 564 VQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD 606
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,088,993
Number of Sequences: 369166
Number of extensions: 1395208
Number of successful extensions: 3381
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3272
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3373
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4602033670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)