Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_J12
(706 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P11611|P2AB_RABIT Serine/threonine protein phosphatase 2... 318 7e-87
sp|P63331|P2AA_RAT Serine/threonine protein phosphatase 2A,... 318 7e-87
sp|P67775|P2AA_HUMAN Serine/threonine protein phosphatase 2... 318 7e-87
sp|P62714|P2AB_HUMAN Serine/threonine protein phosphatase 2... 318 7e-87
sp|P48463|P2AA_CHICK Serine/threonine protein phosphatase 2... 318 7e-87
sp|P11493|P2AB_PIG Serine/threonine protein phosphatase 2A,... 318 7e-87
sp|P23696|P2A_DROME Serine/threonine protein phosphatase PP... 313 3e-85
sp|Q8X178|P2A2_ERYGR Serine/threonine protein phosphatase P... 303 2e-82
sp|Q9HFQ2|P2A1_EMENI Serine/threonine protein phosphatase P... 302 5e-82
sp|P48580|P2A1_NEUCR Serine/threonine protein phosphatase P... 302 7e-82
>sp|P11611|P2AB_RABIT Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 309
Score = 318 bits (816), Expect = 7e-87
Identities = 145/158 (91%), Positives = 152/158 (96%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTALV+ IFCLHGGLSPSIDTLDHI+ALDR+QEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 152 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGI 211
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISETFNH+N LTLVSRAHQLVMEGYNW HD+NVVTIFSAPNYCYRCGN
Sbjct: 212 SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGN 271
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIMELDD+LKY+FLQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 272 QAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309
>sp|P63331|P2AA_RAT Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P63330|P2AA_MOUSE Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 318 bits (816), Expect = 7e-87
Identities = 145/158 (91%), Positives = 152/158 (96%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTALV+ IFCLHGGLSPSIDTLDHI+ALDR+QEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 152 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGI 211
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISETFNH+N LTLVSRAHQLVMEGYNW HD+NVVTIFSAPNYCYRCGN
Sbjct: 212 SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGN 271
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIMELDD+LKY+FLQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 272 QAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309
>sp|P67775|P2AA_HUMAN Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha) (Replication protein C) (RP-C)
sp|P67774|P2AA_BOVIN Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P67777|P2AA_RABIT Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P67776|P2AA_PIG Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 318 bits (816), Expect = 7e-87
Identities = 145/158 (91%), Positives = 152/158 (96%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTALV+ IFCLHGGLSPSIDTLDHI+ALDR+QEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 152 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGI 211
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISETFNH+N LTLVSRAHQLVMEGYNW HD+NVVTIFSAPNYCYRCGN
Sbjct: 212 SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGN 271
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIMELDD+LKY+FLQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 272 QAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309
>sp|P62714|P2AB_HUMAN Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
sp|P62716|P2AB_RAT Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
sp|P62715|P2AB_MOUSE Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 309
Score = 318 bits (816), Expect = 7e-87
Identities = 145/158 (91%), Positives = 152/158 (96%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTALV+ IFCLHGGLSPSIDTLDHI+ALDR+QEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 152 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGI 211
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISETFNH+N LTLVSRAHQLVMEGYNW HD+NVVTIFSAPNYCYRCGN
Sbjct: 212 SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGN 271
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIMELDD+LKY+FLQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 272 QAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309
>sp|P48463|P2AA_CHICK Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 318 bits (816), Expect = 7e-87
Identities = 145/158 (91%), Positives = 152/158 (96%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTALV+ IFCLHGGLSPSIDTLDHI+ALDR+QEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 152 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGI 211
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISETFNH+N LTLVSRAHQLVMEGYNW HD+NVVTIFSAPNYCYRCGN
Sbjct: 212 SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGN 271
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIMELDD+LKY+FLQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 272 QAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 309
>sp|P11493|P2AB_PIG Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 293
Score = 318 bits (816), Expect = 7e-87
Identities = 145/158 (91%), Positives = 152/158 (96%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTALV+ IFCLHGGLSPSIDTLDHI+ALDR+QEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 136 YLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGI 195
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISETFNH+N LTLVSRAHQLVMEGYNW HD+NVVTIFSAPNYCYRCGN
Sbjct: 196 SPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGN 255
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIMELDD+LKY+FLQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 256 QAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 293
>sp|P23696|P2A_DROME Serine/threonine protein phosphatase PP2A (Microtubule star
protein)
Length = 309
Score = 313 bits (802), Expect = 3e-85
Identities = 142/158 (89%), Positives = 152/158 (96%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTALV+ IFCLHGGLSPSID+LDHI+ALDR+QEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 152 YLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGI 211
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISETFN++N LTLVSRAHQLVMEGYNW HD+NVVTIFSAPNYCYRCGN
Sbjct: 212 SPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGN 271
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAA+MELDDSLK++FLQFDPAPRRGEPHVTRRTPDYFL
Sbjct: 272 QAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL 309
>sp|Q8X178|P2A2_ERYGR Serine/threonine protein phosphatase PP2A-2 catalytic subunit
Length = 328
Score = 303 bits (777), Expect = 2e-82
Identities = 139/158 (87%), Positives = 148/158 (93%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
+LPLTAL+EN IFCLHGGLSPSIDTLD+IK+LDRIQEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 171 FLPLTALIENQIFCLHGGLSPSIDTLDNIKSLDRIQEVPHEGPMCDLLWSDPDDRCGWGI 230
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISE FNH+N LTLV+RAHQLVMEGYNWS D+NVVTIFSAPNYCYRCGN
Sbjct: 231 SPRGAGYTFGQDISEAFNHNNGLTLVARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGN 290
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIME+D+ LKYTFLQFDP PR GEP VTRRTPDYFL
Sbjct: 291 QAAIMEIDEHLKYTFLQFDPCPRAGEPMVTRRTPDYFL 328
>sp|Q9HFQ2|P2A1_EMENI Serine/threonine protein phosphatase PP2A catalytic subunit
(Protein phosphatase 2a)
Length = 329
Score = 302 bits (774), Expect = 5e-82
Identities = 138/158 (87%), Positives = 148/158 (93%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTAL+EN IFCLHGGLSPSIDTLD+I++LDRIQEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 172 YLPLTALIENQIFCLHGGLSPSIDTLDNIRSLDRIQEVPHEGPMCDLLWSDPDDRCGWGI 231
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISE FNH+N LTLV+RAHQLVMEGYNWS D+NVVTIFSAPNYCYRCGN
Sbjct: 232 SPRGAGYTFGQDISEAFNHNNGLTLVARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGN 291
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIME+D+ LKYTFLQFDP PR GEP V+RRTPDYFL
Sbjct: 292 QAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL 329
>sp|P48580|P2A1_NEUCR Serine/threonine protein phosphatase PP2A catalytic subunit
Length = 327
Score = 302 bits (773), Expect = 7e-82
Identities = 137/158 (86%), Positives = 148/158 (93%)
Frame = +3
Query: 3 YLPLTALVENSIFCLHGGLSPSIDTLDHIKALDRIQEVPHEGPMCDLLWSDPDDRNGWGI 182
YLPLTAL++N IFCLHGGLSPSIDTLD+I+ALDRIQEVPHEGPMCDLLWSDPDDR GWGI
Sbjct: 170 YLPLTALIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGI 229
Query: 183 SPRGAGYTFGLDISETFNHSNNLTLVSRAHQLVMEGYNWSHDKNVVTIFSAPNYCYRCGN 362
SPRGAGYTFG DISE FNH+N LTL++RAHQLVMEGYNWS D+NVVTIFSAPNYCYRCGN
Sbjct: 230 SPRGAGYTFGQDISEAFNHNNGLTLIARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGN 289
Query: 363 QAAIMELDDSLKYTFLQFDPAPRRGEPHVTRRTPDYFL 476
QAAIME+D+ LKYTFLQFDP PR GEP V+RRTPDYFL
Sbjct: 290 QAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL 327
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,503,183
Number of Sequences: 369166
Number of extensions: 1723281
Number of successful extensions: 4324
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4110
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4220
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6170718545
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)