Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_H13
(576 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q71S22|INVSA_XENLA Inversin-A 78 1e-14
sp|P57078|RIPK4_HUMAN Serine/threonine-protein kinase RIPK4... 77 3e-14
sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G) 76 7e-14
sp|Q8Q0U0|Y045_METMA Hypothetical ANK-repeat protein MM0045 75 9e-14
sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin) 75 1e-13
sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyr... 75 1e-13
sp|Q8UVC3|INVS_CHICK Inversin 75 2e-13
sp|Q80YE7|DAPK1_MOUSE Death-associated protein kinase 1 (DA... 74 3e-13
sp|Q71S21|INVSB_XENLA Inversin-B 73 4e-13
sp|O15084|ANR28_HUMAN Ankyrin repeat domain protein 28 73 4e-13
>sp|Q71S22|INVSA_XENLA Inversin-A
Length = 1007
Score = 78.2 bits (191), Expect = 1e-14
Identities = 46/154 (29%), Positives = 77/154 (50%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L AA SG + + ++ N + +D + + TAL +A MG +++S ++ A ++ D
Sbjct: 357 LHAASLSGQITTVRILLENRVQVDAVDVMKHTALFRACEMGHREVISTLIKGGAKVHLVD 416
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G SP+H+AA G+ D GRTP+ AA G+ +++L+ N A
Sbjct: 417 KDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKA 476
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAY 573
D +IQD NG T LH + +K+L+ A+
Sbjct: 477 DPNIQDKNGRTALHWSCNNGYLDAVKLLLGYSAF 510
Score = 47.0 bits (110), Expect = 3e-05
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Frame = +1
Query: 133 GNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPI 312
GN +V ++ N IN D ++ G T L A G + + A+PN++D G + +
Sbjct: 430 GNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNIQDKNGRTAL 489
Query: 313 HFAASRGHEXXXXXXXXXXXXXXXXDNSGR--TPISYAAQHGHSCIVKLLLLNGA 471
H++ + G+ +N+ TP+ YA GH +++ +L +GA
Sbjct: 490 HWSCNNGYLDAVKLLLGYSAFPNQMENTEERYTPLDYALLGGHQEVIQFMLEHGA 544
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 2/132 (1%)
Frame = +1
Query: 178 LDYKNKLGWTALHKAVIMGSWKIVSEFLR-RSANPNMKDNFGESPIHFAASRGHEXXXXX 354
L++++ G T LH AV G+ ++V R N DN +P+H+AA G+
Sbjct: 210 LNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGYTPIAHL 269
Query: 355 XXXXXXXXXXX-DNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHD 531
D+ G TP+ YAAQ V++LL + + D DL G T A
Sbjct: 270 LLETNNSPNIPSDSQGATPLHYAAQGNCPDTVRVLLSHISVRDEADLEGRTAFMWAAGKG 329
Query: 532 SYKGIKILIDND 567
S + ++ +++ D
Sbjct: 330 SDEVVRTMLELD 341
Score = 39.7 bits (91), Expect = 0.005
Identities = 23/93 (24%), Positives = 40/93 (43%)
Frame = +1
Query: 280 NMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLL 459
+ +D G +P+ ++ D SGRT + AAQ G+ ++KLLL
Sbjct: 38 DQEDQLGRTPLMYSVLGDRRSCAEALLKHGAQVNHPDRSGRTALHLAAQTGNHRLLKLLL 97
Query: 460 LNGADIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
AD +DL T +H H + + +++
Sbjct: 98 SRKADCTHRDLRDITAVHLSTRHQDTRCLALIL 130
Score = 37.7 bits (86), Expect = 0.021
Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 9/125 (7%)
Frame = +1
Query: 178 LDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHE------ 339
+D +++ TALH + + V +R +N + D G+ P+H+AA GH+
Sbjct: 138 VDAQDQRKQTALHWSAYYNRPRHVRLLVRHGSNIGIPDTEGKIPLHWAA--GHKDPEAAL 195
Query: 340 --XXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLL-LNGADIDIQDLNGNTPL 510
D GRTP+ A G+ +V+LL G ++ D TPL
Sbjct: 196 TVRCLLEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPL 255
Query: 511 HHLAM 525
H A+
Sbjct: 256 HWAAL 260
>sp|P57078|RIPK4_HUMAN Serine/threonine-protein kinase RIPK4 (Receptor-interacting
serine/threonine-protein kinase 4) (Ankyrin repeat
domain protein 3) (PKC-delta-interacting protein kinase)
Length = 832
Score = 77.0 bits (188), Expect = 3e-14
Identities = 47/149 (31%), Positives = 69/149 (46%)
Frame = +1
Query: 109 LLFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMK 288
LL A+++G + +++ N N + N+ G T LH AV +V L R + N K
Sbjct: 489 LLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAK 548
Query: 289 DNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNG 468
D + +HFAA G E D GRTP+ A QHG IV++LL G
Sbjct: 549 DEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRG 608
Query: 469 ADIDIQDLNGNTPLHHLAMHDSYKGIKIL 555
D+ +Q + PLH+ A +K+L
Sbjct: 609 VDVSLQGKDAWLPLHYAAWQGHLPIVKLL 637
Score = 61.2 bits (147), Expect = 2e-09
Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 1/156 (0%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRR-SANPNMK 288
+ A G +++ ++ +++ + K W LH A G IV ++ + N +
Sbjct: 589 MHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQ 648
Query: 289 DNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNG 468
G +P+H AA RGH +TP+ AA+ GH+ +LLL G
Sbjct: 649 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRG 708
Query: 469 ADIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
A + +G T LH A + +K+L++ A V
Sbjct: 709 AGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADV 744
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/149 (26%), Positives = 64/149 (42%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L AI SG+ ++ ++ ++D G + LH AV G + L +ANPN+ +
Sbjct: 458 LVDAIVSGDTSKLMKILQPQ-DVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSN 516
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H A R D T + +AAQ+G +LLL A
Sbjct: 517 RRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNA 576
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
++ D G TP+H H ++IL+
Sbjct: 577 SVNEVDFEGRTPMHVACQHGQENIVRILL 605
Score = 50.4 bits (119), Expect = 3e-06
Identities = 32/123 (26%), Positives = 53/123 (43%)
Frame = +1
Query: 199 GWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXX 378
G T LH A G +++ + ++ N+ ++P+H AA GH
Sbjct: 652 GRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGK 711
Query: 379 XXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
+ G T + AA++GH VKLL+ AD+ + T LH A H + ++ L+
Sbjct: 712 EAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 771
Query: 559 DND 567
D
Sbjct: 772 SAD 774
Score = 42.4 bits (98), Expect = 8e-04
Identities = 31/127 (24%), Positives = 52/127 (40%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A ++G+ ++ + G+TALH A G V + A+ +
Sbjct: 689 LHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARG 748
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
++ +H AA+ GH D G + + AAQ H+ V+ LL +GA
Sbjct: 749 PLNQTALHLAAAHGHS-EVVEELVSADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGA 807
Query: 472 DIDIQDL 492
I++Q L
Sbjct: 808 HINLQSL 814
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/93 (23%), Positives = 38/93 (40%)
Frame = +1
Query: 298 GESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADI 477
G S +H A G E + G TP+ A + +V+LLL +
Sbjct: 486 GASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISV 545
Query: 478 DIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+ +D + T LH A + ++L++ +A V
Sbjct: 546 NAKDEDQWTALHFAAQNGDESSTRLLLEKNASV 578
>sp|Q12955|ANK3_HUMAN Ankyrin-3 (ANK-3) (Ankyrin G)
Length = 4377
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/153 (30%), Positives = 72/153 (47%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A SG +V+ +++ + ++ K K T LH + +G IV + L++ A+PN
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAAT 529
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H +A GHE G TP+ AA++G + LLL A
Sbjct: 530 TSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSA 589
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
D +G TPLH A +D+ K +L+D A
Sbjct: 590 SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGA 622
Score = 67.0 bits (162), Expect = 3e-11
Identities = 43/149 (28%), Positives = 70/149 (46%)
Frame = +1
Query: 121 AIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFG 300
A +G+++ L + N ++++ N+ G ALH A G ++VSE L+R AN + G
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 301 ESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADID 480
+ +H A+ G +G TP+ AAQ H +VK LL NGA
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQS 167
Query: 481 IQDLNGNTPLHHLAMHDSYKGIKILIDND 567
+ +G TPL + + +L++ND
Sbjct: 168 LATEDGFTPLAVALQQGHDQVVSLLLEND 196
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/155 (26%), Positives = 67/155 (43%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G ++V ++ + D K G T LH A + K+ L + A+P+
Sbjct: 569 LHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAA 628
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA + G + AAQ GH +V LLL A
Sbjct: 629 KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNA 688
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
++++ + +G TPLH A D ++L++ A+V
Sbjct: 689 NVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHV 723
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 65/152 (42%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G+++V+ ++ N+D K G TALH A + G ++V + AN N +
Sbjct: 78 LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 137
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P++ AA H G TP++ A Q GH +V LLL N
Sbjct: 138 QNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN-- 195
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDND 567
D + LH A D K +L+ ND
Sbjct: 196 --DTKGKVRLPALHIAARKDDTKAAALLLQND 225
Score = 63.2 bits (152), Expect = 5e-10
Identities = 42/155 (27%), Positives = 67/155 (43%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A +++ + ++ + + +D TALH A G +K+ L + ANPN K
Sbjct: 338 LHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKA 397
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H A + SG TPI AA GH IV L+ +GA
Sbjct: 398 LNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGA 457
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+ ++ G T LH A + ++ L+ + A V
Sbjct: 458 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492
Score = 61.2 bits (147), Expect = 2e-09
Identities = 40/153 (26%), Positives = 64/153 (41%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A MD+ ++ + + + G ++H A G +VS L R+AN N+ +
Sbjct: 635 LHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSN 694
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA G TP+ +G+ IV LL + A
Sbjct: 695 KSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSA 754
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
++ + NG TPLH A I +L+ N+A
Sbjct: 755 KVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNA 787
Score = 60.1 bits (144), Expect = 4e-09
Identities = 43/153 (28%), Positives = 71/153 (46%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A+ G+ V+ ++ N D K K+ ALH A K + L+ N +++
Sbjct: 177 LAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVES 232
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA G+ + TP+ A++ G++ +VKLLL GA
Sbjct: 233 KSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGA 292
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
ID + +G TPLH A + +++L+D A
Sbjct: 293 KIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA 325
Score = 59.7 bits (143), Expect = 5e-09
Identities = 34/130 (26%), Positives = 58/130 (44%)
Frame = +1
Query: 121 AIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFG 300
A G++D++ ++ N++ NK G T LH A + + + A+ + + G
Sbjct: 671 AAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMG 730
Query: 301 ESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADID 480
+P+H G+ +G TP+ AAQ GH+ I+ +LL N A +
Sbjct: 731 YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPN 790
Query: 481 IQDLNGNTPL 510
+NGNT L
Sbjct: 791 ELTVNGNTAL 800
Score = 59.3 bits (142), Expect = 7e-09
Identities = 42/155 (27%), Positives = 62/155 (40%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A N V L ++ + K G+T LH A I + L A+ N
Sbjct: 602 LHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVT 661
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G + +H AA GH + SG TP+ AAQ + ++L+ GA
Sbjct: 662 RQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGA 721
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+D Q G TPLH + + K + L+ + A V
Sbjct: 722 HVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKV 756
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/155 (27%), Positives = 66/155 (42%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A GN +++ ++ +D K + G T LH G ++V L R+A K
Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKT 331
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G SP+H A H N T + AA GH + K+LL A
Sbjct: 332 KNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKA 391
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+ + + LNG TPLH + K +++L+ + A +
Sbjct: 392 NPNAKALNGFTPLHIACKKNRIKVMELLLKHGASI 426
Score = 58.5 bits (140), Expect = 1e-08
Identities = 40/153 (26%), Positives = 65/153 (42%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A + V+ ++ + ++ + G T +H A MG IVS+ + A+PN +
Sbjct: 404 LHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTN 463
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
GE+ +H AA G +TP+ +A+ G + IV+ LL GA
Sbjct: 464 VRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
+ +G TPLH A L+D+ A
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA 556
Score = 52.0 bits (123), Expect = 1e-06
Identities = 37/155 (23%), Positives = 65/155 (41%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L+ A +++V+ F++ N + + G+T L A+ G ++VS L ++
Sbjct: 144 LYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVR- 202
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
+H AA + SG TP+ AA +G+ + LLL A
Sbjct: 203 ---LPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAA 259
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+D N TPLH + + +K+L+D A +
Sbjct: 260 AVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Score = 48.9 bits (115), Expect = 9e-06
Identities = 31/115 (26%), Positives = 52/115 (45%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A ++V +++ ++D + K+G+T LH G+ KIV+ L+ SA N K
Sbjct: 701 LHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKT 760
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLL 456
G +P+H AA +GH +G T + A + G+ +V L
Sbjct: 761 KNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815
Score = 38.1 bits (87), Expect = 0.016
Identities = 27/105 (25%), Positives = 45/105 (42%)
Frame = +1
Query: 262 RRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSC 441
+RS + K + S + AA GH + +G + A++ GH
Sbjct: 30 KRSRDRKKKSDANASYLR-AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVE 88
Query: 442 IVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+V LL A++D GNT LH ++ + +K+L+ N A V
Sbjct: 89 VVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANV 133
>sp|Q8Q0U0|Y045_METMA Hypothetical ANK-repeat protein MM0045
Length = 360
Score = 75.5 bits (184), Expect = 9e-14
Identities = 49/151 (32%), Positives = 79/151 (52%)
Frame = +1
Query: 118 AAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNF 297
A I+ G D+I ++ N +L+++++ G TAL AV +G I + + + N++D
Sbjct: 142 AKIERG--DIIDLLVKNGADLNFQDENGETALKFAVKVGYKNIADQLIDAGTDLNIQDEN 199
Query: 298 GESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADI 477
GE+ + AA R H DNSG+T + A + GH IV+LL+ GAD+
Sbjct: 200 GETALICAADRAHRDIAELLIKAGADLNIQDNSGKTALVAATKIGHKGIVELLVNAGADL 259
Query: 478 DIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
++QD NGNT L + A + +LI+ A
Sbjct: 260 NLQDKNGNTALIYAADRGYRDIVNLLIEGGA 290
Score = 68.6 bits (166), Expect = 1e-11
Identities = 48/151 (31%), Positives = 74/151 (49%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L +A D G DVI ++ + NLD +++ G TAL A + I+ ++ A+ N +D
Sbjct: 105 LISAADKGYRDVIGLLIESGPNLDLQDENGNTALISAAKIERGDIIDLLVKNGADLNFQD 164
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
GE+ + FA G++ D +G T + AA H I +LL+ GA
Sbjct: 165 ENGETALKFAVKVGYKNIADQLIDAGTDLNIQDENGETALICAADRAHRDIAELLIKAGA 224
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDN 564
D++IQD +G T L A +KGI L+ N
Sbjct: 225 DLNIQDNSGKTAL-VAATKIGHKGIVELLVN 254
Score = 62.8 bits (151), Expect = 6e-10
Identities = 39/131 (29%), Positives = 64/131 (48%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A D + D+ ++ +L+ ++ G TAL A +G IV + A+ N++D
Sbjct: 204 LICAADRAHRDIAELLIKAGADLNIQDNSGKTALVAATKIGHKGIVELLVNAGADLNLQD 263
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G + + +AA RG+ D +G T + ++AQ G IV+LL+ GA
Sbjct: 264 KNGNTALIYAADRGYRDIVNLLIEGGASLNIPDEAGLTALMFSAQTGRKDIVELLIKAGA 323
Query: 472 DIDIQDLNGNT 504
DI+I+D N T
Sbjct: 324 DINIEDKNNKT 334
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/61 (36%), Positives = 35/61 (57%)
Frame = +1
Query: 388 DNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDND 567
D G+T + AA G+ ++ LL+ +G ++D+QD NGNT L A + I +L+ N
Sbjct: 98 DAYGKTALISAADKGYRDVIGLLIESGPNLDLQDENGNTALISAAKIERGDIIDLLVKNG 157
Query: 568 A 570
A
Sbjct: 158 A 158
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/105 (23%), Positives = 47/105 (44%)
Frame = +1
Query: 25 KIGDYKGLKSVINLDIXXXXXXXXXXXXLLFAAIDSGNMDVILFVMSNMINLDYKNKLGW 204
KIG ++ ++N L++AA D G D++ ++ +L+ ++ G
Sbjct: 242 KIGHKGIVELLVNAGADLNLQDKNGNTALIYAA-DRGYRDIVNLLIEGGASLNIPDEAGL 300
Query: 205 TALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHE 339
TAL + G IV ++ A+ N++D ++ AA G E
Sbjct: 301 TALMFSAQTGRKDIVELLIKAGADINIEDKNNKTAADLAAEVGFE 345
>sp|Q02357|ANK1_MOUSE Ankyrin-1 (Erythrocyte ankyrin)
Length = 1862
Score = 75.1 bits (183), Expect = 1e-13
Identities = 47/153 (30%), Positives = 72/153 (47%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A ++ V+ ++ ++D + G T LH A MG IV L+R A+PN+ +
Sbjct: 371 LHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSN 430
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
E+P+H AA GH +TP+ AA+ GH+ +VKLLL NGA
Sbjct: 431 VKVETPLHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGA 490
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
++ G+TPLH A L++ +A
Sbjct: 491 SPNLATTAGHTPLHTAAREGHVDTALALLEKEA 523
Score = 65.1 bits (157), Expect = 1e-10
Identities = 38/155 (24%), Positives = 67/155 (43%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A+ N+D++ ++ + G+T LH A ++ L+ + N +
Sbjct: 569 LHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANAES 628
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA GH + SG TP+ +Q GH + +L+ +G
Sbjct: 629 VQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLIKHGV 688
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+D G TPLH + + + K +K L+ + A V
Sbjct: 689 TVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 723
Score = 62.8 bits (151), Expect = 6e-10
Identities = 39/140 (27%), Positives = 65/140 (46%)
Frame = +1
Query: 157 VMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGH 336
++ N N D +K G+T LH A + + L R A+ N G +P+H A+ RG+
Sbjct: 188 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGN 247
Query: 337 EXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHH 516
TP+ AA++GH I ++LL +GA I + NG +P+H
Sbjct: 248 VIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 307
Query: 517 LAMHDSYKGIKILIDNDAYV 576
A D +++L+ +A +
Sbjct: 308 AAQGDHLDCVRLLLQYNAEI 327
Score = 59.3 bits (142), Expect = 7e-09
Identities = 35/124 (28%), Positives = 57/124 (45%)
Frame = +1
Query: 199 GWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXX 378
G T LH A G ++V+ L + AN N+ + G +P+H + GH
Sbjct: 631 GVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTV 690
Query: 379 XXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
G TP+ A+ +G+ +VK LL + AD++ + G +PLH A + +L+
Sbjct: 691 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 750
Query: 559 DNDA 570
N A
Sbjct: 751 KNGA 754
Score = 58.9 bits (141), Expect = 9e-09
Identities = 40/130 (30%), Positives = 58/130 (44%)
Frame = +1
Query: 121 AIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFG 300
A SGN+D L + N ++++ N+ G LH A G K+V E L + G
Sbjct: 15 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 74
Query: 301 ESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADID 480
+ +H AA G + G TP+ AAQ H +VK LL NGA+ +
Sbjct: 75 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 134
Query: 481 IQDLNGNTPL 510
+ +G TPL
Sbjct: 135 VATEDGFTPL 144
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/133 (27%), Positives = 56/133 (42%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G+ +++ ++S N + NK G T LH G + ++ +
Sbjct: 635 LHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTVDATT 694
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H A+ G+ G +P+ AAQ GH+ IV LLL NGA
Sbjct: 695 RMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 754
Query: 472 DIDIQDLNGNTPL 510
+ NG TPL
Sbjct: 755 SPNEVSSNGTTPL 767
Score = 58.2 bits (139), Expect = 1e-08
Identities = 41/153 (26%), Positives = 72/153 (47%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A+ G+ +V+ +++IN K K+ ALH A + + L+ NP++
Sbjct: 144 LAVALQQGHENVV----AHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLS 199
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA + +G TP+ A++ G+ +V+LLL GA
Sbjct: 200 KTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA 259
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
I+ + + TPLH A + + +IL+D+ A
Sbjct: 260 QIETRTKDELTPLHCAARNGHVRISEILLDHGA 292
Score = 57.8 bits (138), Expect = 2e-08
Identities = 40/152 (26%), Positives = 66/152 (43%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G++ +++ ++ I L+ K G TALH A + G ++V E + AN N +
Sbjct: 45 LHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQS 104
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P++ AA H G TP++ A Q GH +V L+ G
Sbjct: 105 QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGT 164
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDND 567
++ LH A +D + +L+ ND
Sbjct: 165 KGKVR----LPALHIAARNDDTRTAAVLLQND 192
Score = 56.6 bits (135), Expect = 4e-08
Identities = 42/145 (28%), Positives = 66/145 (45%)
Frame = +1
Query: 136 NMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIH 315
N++V +++ ++++ + G T LH A G+ +V L R A + +P+H
Sbjct: 214 NLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLH 273
Query: 316 FAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLN 495
AA GH +G +PI AAQ H V+LLL A+ID L+
Sbjct: 274 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLD 333
Query: 496 GNTPLHHLAMHDSYKGIKILIDNDA 570
TPLH A ++ K+L+D A
Sbjct: 334 HLTPLHVAAHCGHHRVAKVLLDKGA 358
Score = 54.7 bits (130), Expect = 2e-07
Identities = 38/154 (24%), Positives = 63/154 (40%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G++ ++ ++ + + N T LH A G ++ L+ A N K
Sbjct: 404 LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKA 463
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
++P+H AA GH +G TP+ AA+ GH LL A
Sbjct: 464 KDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEA 523
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAY 573
G TPLH A + + ++L+++DA+
Sbjct: 524 SQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAH 557
Score = 53.5 bits (127), Expect = 4e-07
Identities = 42/155 (27%), Positives = 63/155 (40%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A GN+ ++ ++ ++ + K T LH A G +I L A K
Sbjct: 239 LHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 298
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G SPIH AA H TP+ AA GH + K+LL GA
Sbjct: 299 KNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 358
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+ + LNG TPLH + + +++L+ A +
Sbjct: 359 KPNSRALNGFTPLHIACKKNHIRVMELLLKTGASI 393
Score = 53.1 bits (126), Expect = 5e-07
Identities = 36/153 (23%), Positives = 60/153 (39%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G++D L ++ + K G+T LH A G ++ L A+PN
Sbjct: 503 LHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAG 562
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H A + +G TP+ AA+ + + LL G
Sbjct: 563 KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGG 622
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
+ + + G TPLH A + + +L+ A
Sbjct: 623 SANAESVQGVTPLHLAAQEGHTEMVALLLSKQA 655
Score = 52.4 bits (124), Expect = 8e-07
Identities = 29/108 (26%), Positives = 53/108 (49%)
Frame = +1
Query: 133 GNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPI 312
G++ V ++ + + +D ++G+T LH A G+ K+V L+ A+ N K G SP+
Sbjct: 675 GHVLVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPL 734
Query: 313 HFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLL 456
H AA +GH ++G TP++ A + G+ + +L
Sbjct: 735 HQAAQQGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLGYISVTDVL 782
Score = 46.6 bits (109), Expect = 4e-05
Identities = 23/75 (30%), Positives = 42/75 (56%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A GN+ ++ F++ + +++ K KLG++ LH+A G IV+ L+ A+PN
Sbjct: 701 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS 760
Query: 292 NFGESPIHFAASRGH 336
+ G +P+ A G+
Sbjct: 761 SNGTTPLAIAKRLGY 775
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/122 (24%), Positives = 52/122 (42%)
Frame = +1
Query: 205 TALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXX 384
T+ +A G+ + LR + N + G + +H A+ GH
Sbjct: 10 TSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILET 69
Query: 385 XDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDN 564
G T + AA G +V+ L+ GA+++ Q G TPL+ A + + +K L++N
Sbjct: 70 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 129
Query: 565 DA 570
A
Sbjct: 130 GA 131
Score = 43.5 bits (101), Expect = 4e-04
Identities = 37/153 (24%), Positives = 62/153 (40%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A +G++ + ++ + + K K G + +H A V L+ +A +
Sbjct: 272 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDIT 331
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
+P+H AA GH +G TP+ A + H +++LLL GA
Sbjct: 332 LDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGA 391
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
ID +G TPLH + +K L+ A
Sbjct: 392 SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGA 424
>sp|P16157|ANK1_HUMAN Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin R)
Length = 1881
Score = 75.1 bits (183), Expect = 1e-13
Identities = 46/153 (30%), Positives = 74/153 (48%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A ++ V+ ++ ++D + G T LH A MG IV L+R A+PN+ +
Sbjct: 375 LHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSN 434
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
E+P+H AA GH +TP+ AA+ GH+ +VKLLL N A
Sbjct: 435 VKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNA 494
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
+ ++ G+TPLH A + + L++ +A
Sbjct: 495 NPNLATTAGHTPLHIAAREGHVETVLALLEKEA 527
Score = 72.8 bits (177), Expect = 6e-13
Identities = 44/149 (29%), Positives = 69/149 (46%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A +G+ +V +++ N ++ K K T LH A +G +V L +ANPN+
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 500
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA GH G TP+ AA++G + +LLL A
Sbjct: 501 TAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDA 560
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
+ NG TPLH H++ +K+L+
Sbjct: 561 HPNAAGKNGLTPLHVAVHHNNLDIVKLLL 589
Score = 64.7 bits (156), Expect = 2e-10
Identities = 40/140 (28%), Positives = 65/140 (46%)
Frame = +1
Query: 157 VMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGH 336
++ N N D +K G+T LH A + + L R A+ N G +P+H A+ RG+
Sbjct: 192 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGN 251
Query: 337 EXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHH 516
TP+ AA++GH I ++LL +GA I + NG +P+H
Sbjct: 252 VIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHM 311
Query: 517 LAMHDSYKGIKILIDNDAYV 576
A D +++L+ DA +
Sbjct: 312 AAQGDHLDCVRLLLQYDAEI 331
Score = 64.7 bits (156), Expect = 2e-10
Identities = 39/155 (25%), Positives = 67/155 (43%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A+ N+D++ ++ + G+T LH A ++ L+ + N +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA GH + SG TP+ AQ GH + +L+ +G
Sbjct: 633 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGV 692
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+D G TPLH + + + K +K L+ + A V
Sbjct: 693 MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADV 727
Score = 60.1 bits (144), Expect = 4e-09
Identities = 36/124 (29%), Positives = 57/124 (45%)
Frame = +1
Query: 199 GWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXX 378
G T LH A G ++V+ L + AN N+ + G +P+H A GH
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMV 694
Query: 379 XXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
G TP+ A+ +G+ +VK LL + AD++ + G +PLH A + +L+
Sbjct: 695 DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Query: 559 DNDA 570
N A
Sbjct: 755 KNGA 758
Score = 58.9 bits (141), Expect = 9e-09
Identities = 40/130 (30%), Positives = 58/130 (44%)
Frame = +1
Query: 121 AIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFG 300
A SGN+D L + N ++++ N+ G LH A G K+V E L + G
Sbjct: 19 AARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKG 78
Query: 301 ESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADID 480
+ +H AA G + G TP+ AAQ H +VK LL NGA+ +
Sbjct: 79 NTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQN 138
Query: 481 IQDLNGNTPL 510
+ +G TPL
Sbjct: 139 VATEDGFTPL 148
Score = 58.9 bits (141), Expect = 9e-09
Identities = 38/124 (30%), Positives = 53/124 (42%)
Frame = +1
Query: 205 TALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXX 384
T LH A G ++ L + A PN + G +P+H A + H
Sbjct: 340 TPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDA 399
Query: 385 XDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDN 564
SG TP+ A+ GH IVK LL GA ++ ++ TPLH A + K L+ N
Sbjct: 400 VTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 459
Query: 565 DAYV 576
A V
Sbjct: 460 KAKV 463
Score = 58.2 bits (139), Expect = 1e-08
Identities = 41/153 (26%), Positives = 72/153 (47%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A+ G+ +V+ +++IN K K+ ALH A + + L+ NP++
Sbjct: 148 LAVALQQGHENVV----AHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLS 203
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H AA + +G TP+ A++ G+ +V+LLL GA
Sbjct: 204 KTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGA 263
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
I+ + + TPLH A + + +IL+D+ A
Sbjct: 264 QIETKTKDELTPLHCAARNGHVRISEILLDHGA 296
Score = 57.8 bits (138), Expect = 2e-08
Identities = 40/152 (26%), Positives = 66/152 (43%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G++ +++ ++ I L+ K G TALH A + G ++V E + AN N +
Sbjct: 49 LHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQS 108
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P++ AA H G TP++ A Q GH +V L+ G
Sbjct: 109 QKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGT 168
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDND 567
++ LH A +D + +L+ ND
Sbjct: 169 KGKVR----LPALHIAARNDDTRTAAVLLQND 196
Score = 57.4 bits (137), Expect = 3e-08
Identities = 43/145 (29%), Positives = 66/145 (45%)
Frame = +1
Query: 136 NMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIH 315
N++V +++ ++++ + G T LH A G+ +V L R A K +P+H
Sbjct: 218 NLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLH 277
Query: 316 FAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLN 495
AA GH +G +PI AAQ H V+LLL A+ID L+
Sbjct: 278 CAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLD 337
Query: 496 GNTPLHHLAMHDSYKGIKILIDNDA 570
TPLH A ++ K+L+D A
Sbjct: 338 HLTPLHVAAHCGHHRVAKVLLDKGA 362
Score = 57.0 bits (136), Expect = 3e-08
Identities = 36/133 (27%), Positives = 56/133 (42%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G+ +++ ++S N + NK G T LH G + ++ +
Sbjct: 639 LHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATT 698
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H A+ G+ G +P+ AAQ GH+ IV LLL NGA
Sbjct: 699 RMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGA 758
Query: 472 DIDIQDLNGNTPL 510
+ +G TPL
Sbjct: 759 SPNEVSSDGTTPL 771
Score = 55.8 bits (133), Expect = 7e-08
Identities = 39/154 (25%), Positives = 63/154 (40%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G++ ++ ++ + + N T LH A G ++ L+ A N K
Sbjct: 408 LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKA 467
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
++P+H AA GH +G TP+ AA+ GH V LL A
Sbjct: 468 KDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEA 527
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAY 573
G TPLH A + + ++L++ DA+
Sbjct: 528 SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAH 561
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/155 (27%), Positives = 63/155 (40%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A GN+ ++ ++ ++ K K T LH A G +I L A K
Sbjct: 243 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 302
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G SPIH AA H TP+ AA GH + K+LL GA
Sbjct: 303 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+ + LNG TPLH + + +++L+ A +
Sbjct: 363 KPNSRALNGFTPLHIACKKNHVRVMELLLKTGASI 397
Score = 52.8 bits (125), Expect = 6e-07
Identities = 30/115 (26%), Positives = 53/115 (46%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L G++ V ++ + + +D ++G+T LH A G+ K+V L+ A+ N K
Sbjct: 672 LHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLL 456
G SP+H AA +GH + G TP++ A + G+ + +L
Sbjct: 732 KLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 52.4 bits (124), Expect = 8e-07
Identities = 33/124 (26%), Positives = 57/124 (45%)
Frame = +1
Query: 199 GWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXX 378
G+T LH A +++ L+ A+ + G +P+H A+ GH
Sbjct: 371 GFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASP 430
Query: 379 XXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
+ TP+ AA+ GH+ + K LL N A ++ + + TPLH A +K+L+
Sbjct: 431 NVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL 490
Query: 559 DNDA 570
+N+A
Sbjct: 491 ENNA 494
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/122 (24%), Positives = 52/122 (42%)
Frame = +1
Query: 205 TALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXX 384
T+ +A G+ + LR + N + G + +H A+ GH
Sbjct: 14 TSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILET 73
Query: 385 XDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDN 564
G T + AA G +V+ L+ GA+++ Q G TPL+ A + + +K L++N
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLEN 133
Query: 565 DA 570
A
Sbjct: 134 GA 135
>sp|Q8UVC3|INVS_CHICK Inversin
Length = 1106
Score = 74.7 bits (182), Expect = 2e-13
Identities = 46/154 (29%), Positives = 75/154 (48%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L AA SG++ + ++ +D + + T L +A MG +++ ++ A ++ D
Sbjct: 361 LHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLVD 420
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G SP+H+AA G+ D +GRTP+ AA G+ + +LL N A
Sbjct: 421 QDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMVVLLENNA 480
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAY 573
D +IQD G T LH L + IK+L+ DA+
Sbjct: 481 DPNIQDKEGRTALHWLCNNGYLDAIKLLLGFDAF 514
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = +1
Query: 211 LHKAVIMGSWKIVSEFLRRSAN-PNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXXX 387
+H A + G + + + ++ + +D FG +P+ +
Sbjct: 18 VHAAAVNGDKSTLLKLIAGNSELKDKEDQFGRTPLMYCVLADRVDCAEALLKAGADVNRA 77
Query: 388 DNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDND 567
D S RT + AAQ G+ +KLLL + +DL G TPLH H S K + +L+ +
Sbjct: 78 DRSRRTALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLKHM 137
Query: 568 A 570
A
Sbjct: 138 A 138
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Frame = +1
Query: 175 NLDYKNKLGWTALHK-AVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGH-EXXX 348
+++ K L W A +K + + K + E + N +D G +P+HFA + G+
Sbjct: 179 DIEGKIPLHWAANNKDPSAIHTVKCILEAAPTESLLNWQDYEGRTPLHFAVADGNVAVVD 238
Query: 349 XXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLL-LNGADIDIQDLNGNTPLHHLAM 525
DN RTP+ +AA GH+ IV LLL N D G TPLH+ A
Sbjct: 239 VLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIPSDSQGATPLHYAAQ 298
Query: 526 HDSYKGIKILI 558
+ + +++ +
Sbjct: 299 SNFAETVEVFL 309
Score = 42.4 bits (98), Expect = 8e-04
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Frame = +1
Query: 205 TALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXX 384
TALH A G+++ + L R N KD G +P+H
Sbjct: 83 TALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLKHMAPGEV 142
Query: 385 X--DNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLA 522
D + +T + ++A + + VKLL+ + ++I I D+ G PLH A
Sbjct: 143 DTQDRNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWAA 190
Score = 38.5 bits (88), Expect = 0.012
Identities = 30/139 (21%), Positives = 60/139 (43%), Gaps = 7/139 (5%)
Frame = +1
Query: 178 LDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHE------ 339
+D +++ TALH + + + V ++ +N + D G+ P+H+AA+
Sbjct: 142 VDTQDRNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWAANNKDPSAIHTV 201
Query: 340 XXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLL-LNGADIDIQDLNGNTPLHH 516
D GRTP+ +A G+ +V +L G ++ D TPLH
Sbjct: 202 KCILEAAPTESLLNWQDYEGRTPLHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHW 261
Query: 517 LAMHDSYKGIKILIDNDAY 573
A+ + + +L++ + +
Sbjct: 262 AALLGHAQIVHLLLERNKF 280
Score = 38.5 bits (88), Expect = 0.012
Identities = 47/192 (24%), Positives = 68/192 (35%), Gaps = 37/192 (19%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMS-NMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNM- 285
L A+ GN+ V+ + S N+ + L T LH A ++G +IV L R+ +
Sbjct: 225 LHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIP 284
Query: 286 KDNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHG----------- 432
D+ G +P+H+AA D GRT +AA G
Sbjct: 285 SDSQGATPLHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDL 344
Query: 433 ------------------------HSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYK 540
H VKLLL A +D D+ +TPL +
Sbjct: 345 KLDIDINMTDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKE 404
Query: 541 GIKILIDNDAYV 576
I+ LI A V
Sbjct: 405 VIQTLIKGGARV 416
>sp|Q80YE7|DAPK1_MOUSE Death-associated protein kinase 1 (DAP kinase 1)
Length = 1442
Score = 73.6 bits (179), Expect = 3e-13
Identities = 45/155 (29%), Positives = 74/155 (47%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
++ A G++D + F+ N LD K+K G TALH A G +V +NP+ +D
Sbjct: 416 IYWASRHGHVDTLKFLNENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQD 475
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
E+P+H AA G+ + G TP+ A+ G+ IV+ L +GA
Sbjct: 476 KEEETPLHCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGA 535
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
D++ D +G+ LH + IK L+ + ++V
Sbjct: 536 DLNASDKDGHIALHLAVRRCQMEVIKTLLGHGSFV 570
Score = 64.7 bits (156), Expect = 2e-10
Identities = 39/134 (29%), Positives = 62/134 (46%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G+ DV+ + S N D+++K T LH A G + + N N+K+
Sbjct: 449 LHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGCNVNIKN 508
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
GE+P+ A++RG+ D G + A + ++K LL +G+
Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRRCQMEVIKTLLGHGS 568
Query: 472 DIDIQDLNGNTPLH 513
+D QD +GNTPLH
Sbjct: 569 FVDFQDRHGNTPLH 582
Score = 52.0 bits (123), Expect = 1e-06
Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 2/156 (1%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G D++ + + +L+ +K G ALH AV +++ L + + +D
Sbjct: 515 LLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRRCQMEVIKTLLGHGSFVDFQD 574
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G +P+H A G + GRTP+ AA +G +V+ L L GA
Sbjct: 575 RHGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGA 634
Query: 472 DIDIQDLNGNT--PLHHLAMHDSYKGIKILIDNDAY 573
+++ +G T L H+ G+ + D +
Sbjct: 635 NVEALTSDGKTAEDLAKAEQHEHVAGLLARLRKDTH 670
>sp|Q71S21|INVSB_XENLA Inversin-B
Length = 1002
Score = 73.2 bits (178), Expect = 4e-13
Identities = 44/154 (28%), Positives = 75/154 (48%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L AA SG + + ++ N D + + T L +A MG ++++ ++ A ++ D
Sbjct: 357 LHAASLSGQITTVRILLENRAQADAVDVMKHTPLFRACEMGHREVIATLIKGGAKVHLVD 416
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G SP+H+AA G+ D GRTP+ AA G+ +++L+ N A
Sbjct: 417 KDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKA 476
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAY 573
D +IQD NG T LH + +K+L+ +A+
Sbjct: 477 DPNIQDKNGRTALHWSCNNGYLDAVKLLLGYNAF 510
Score = 47.0 bits (110), Expect = 3e-05
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Frame = +1
Query: 133 GNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPI 312
GN +V ++ N IN D ++ G T L A G + + A+PN++D G + +
Sbjct: 430 GNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNIQDKNGRTAL 489
Query: 313 HFAASRGHEXXXXXXXXXXXXXXXXDNSGR--TPISYAAQHGHSCIVKLLLLNGA 471
H++ + G+ +N+ TP+ YA GH +++ +L +GA
Sbjct: 490 HWSCNNGYLDAVKLLLGYNAFPNQMENTEERYTPLDYALLGGHQEVIQFMLEHGA 544
Score = 46.2 bits (108), Expect = 6e-05
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 2/130 (1%)
Frame = +1
Query: 178 LDYKNKLGWTALHKAVIMGSWKIVSEFLR-RSANPNMKDNFGESPIHFAASRGHEXXXXX 354
L++++ G T LH AV G+ ++V R N DN +P+H+AA GH
Sbjct: 210 LNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAHL 269
Query: 355 XXXXXXXXXXX-DNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHD 531
D+ G TP+ YAAQ V++LL + + D DL G T L A
Sbjct: 270 LLERNNSPNIPSDSQGATPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKG 329
Query: 532 SYKGIKILID 561
S + ++ +++
Sbjct: 330 SDEVVRTMLE 339
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/93 (26%), Positives = 40/93 (43%)
Frame = +1
Query: 280 NMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLL 459
+ +D G +P+ ++ D SGRT + AAQ G+ ++KLLL
Sbjct: 38 DQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRPDRSGRTALHLAAQTGNHRLLKLLL 97
Query: 460 LNGADIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
AD +DL T LH H + + +L+
Sbjct: 98 SRKADCTHRDLCDITALHLSTRHQDTQCLVLLL 130
Score = 37.4 bits (85), Expect = 0.027
Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 9/125 (7%)
Frame = +1
Query: 178 LDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHE------ 339
+D +++ TALH + + V +R +N + D G+ P+H+AA GH+
Sbjct: 138 VDAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWAA--GHKDPEAAL 195
Query: 340 --XXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLL-LNGADIDIQDLNGNTPL 510
D GRTP+ A G+ +V+LL G ++ D TPL
Sbjct: 196 TVRCLFEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPL 255
Query: 511 HHLAM 525
H A+
Sbjct: 256 HWAAL 260
>sp|O15084|ANR28_HUMAN Ankyrin repeat domain protein 28
Length = 1086
Score = 73.2 bits (178), Expect = 4e-13
Identities = 48/154 (31%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L AA SG + V+ +++ ++++ N G T LH A G +V+E + A N K+
Sbjct: 243 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKN 302
Query: 292 NFGESPIHFAASRGH-EXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNG 468
G +P+HFAA+ H G+TP+ A HG + ++ +G
Sbjct: 303 EKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSG 362
Query: 469 ADIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
A ID +D NGNTPLH A + I LI + A
Sbjct: 363 AVIDCEDKNGNTPLHIAARYGHELLINTLITSGA 396
Score = 72.8 bits (177), Expect = 6e-13
Identities = 39/149 (26%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Frame = +1
Query: 133 GNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPI 312
G+++V+ ++S+ + K+K +T LH A G +V L + N + +G +P+
Sbjct: 217 GHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPL 276
Query: 313 HFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCI-VKLLLLNGADIDIQD 489
H A G + + G TP+ +AA H + ++LL+ NGAD++++
Sbjct: 277 HVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKS 336
Query: 490 LNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+G TPLH A+H + + +I + A +
Sbjct: 337 KDGKTPLHMTALHGRFSRSQTIIQSGAVI 365
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/155 (29%), Positives = 75/155 (48%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L AA G+ ++I ++ + ++ K+ T LH+AV S + V L+ SA+ N +D
Sbjct: 78 LHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARD 137
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
++P+H AA+ D +GRT + +AA GH +VKLLL GA
Sbjct: 138 KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGA 197
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
+I+ D +H A + +K+L+ + A V
Sbjct: 198 NINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV 232
Score = 67.4 bits (163), Expect = 2e-11
Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 6/156 (3%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L ++ +G+ D + +++ N+D K+K G TALH+ + G + V L+ A ++D
Sbjct: 690 LMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRD 749
Query: 292 NFGESPIHFAASRGH----EXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLL 459
+ G +PIH +A+ GH DN G T + +A +GH V+LLL
Sbjct: 750 SRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLL 809
Query: 460 LNGADIDIQDLNGN--TPLHHLAMHDSYKGIKILID 561
Q GN +PLH ++D+ ++LID
Sbjct: 810 EQEV---FQKTEGNAFSPLHCAVINDNEGAAEMLID 842
Score = 62.8 bits (151), Expect = 6e-10
Identities = 40/150 (26%), Positives = 67/150 (44%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A+ S + + + ++ + +++ ++K T LH A + K + +N N+ D
Sbjct: 111 LHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSD 170
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGA 471
G + +H AA GH D R I +AA GH +VKLL+ +GA
Sbjct: 171 RAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGA 230
Query: 472 DIDIQDLNGNTPLHHLAMHDSYKGIKILID 561
++ +D TPLH A +K L+D
Sbjct: 231 EVTCKDKKSYTPLHAAASSGMISVVKYLLD 260
Score = 60.8 bits (146), Expect = 2e-09
Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Frame = +1
Query: 178 LDYKNKLGWTALHKAVIMGSWKIVSEFL-RRSANPNMKDNFGESPIHFAASRGHEXXXXX 354
++ KN+ G+T LH A + E L A+ NMK G++P+H A G
Sbjct: 298 VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQT 357
Query: 355 XXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAM 525
D +G TP+ AA++GH ++ L+ +GAD + ++G PLH A+
Sbjct: 358 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAAL 414
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/154 (27%), Positives = 67/154 (43%)
Frame = +1
Query: 109 LLFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMK 288
L FAA + + ++ N +++ K+K G T LH + G + ++ A + +
Sbjct: 309 LHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCE 368
Query: 289 DNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNG 468
D G +P+H AA GHE G P+ AA G S + LL +G
Sbjct: 369 DKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSG 428
Query: 469 ADIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
DID D G T LH A + + + +L++ A
Sbjct: 429 FDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGA 462
Score = 58.2 bits (139), Expect = 1e-08
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 1/140 (0%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A SG D ++S+ ++D + G T LH A G+ + ++ L A+ N KD
Sbjct: 409 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD 468
Query: 292 NFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGRTPISYAA-QHGHSCIVKLLLLNG 468
FG SP+H+AA+ + D G TP+ YAA ++ LL N
Sbjct: 469 KFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRND 528
Query: 469 ADIDIQDLNGNTPLHHLAMH 528
A+ ++D G +H+ A +
Sbjct: 529 ANPGVRDKQGYNAVHYSAAY 548
Score = 58.2 bits (139), Expect = 1e-08
Identities = 42/157 (26%), Positives = 72/157 (45%), Gaps = 4/157 (2%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKD 291
L A G+ + ++ ++++LD +N G T L A G + V + + A+ +KD
Sbjct: 587 LHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKD 646
Query: 292 NF-GESPIHFAASRGHEXXXXXXXXXXXXXXXXD---NSGRTPISYAAQHGHSCIVKLLL 459
+PIH AA+ GH D +G+TP+ + +GH+ V LL
Sbjct: 647 YILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLL 706
Query: 460 LNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDA 570
GA++D +D G T LH A+ + + L+ + A
Sbjct: 707 NKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGA 743
Score = 57.0 bits (136), Expect = 3e-08
Identities = 43/168 (25%), Positives = 76/168 (45%), Gaps = 13/168 (7%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGS-WKIVSEFLRRSANPNMK 288
LFA + SG +++ +LD + G T LH A + K + LR ANP ++
Sbjct: 487 LFALVGSG---------ASVNDLDER---GCTPLHYAATSDTDGKCLEYLLRNDANPGVR 534
Query: 289 DNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSGR------------TPISYAAQHG 432
D G + +H++A+ GH + SG +P+ AA HG
Sbjct: 535 DKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHG 594
Query: 433 HSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDNDAYV 576
H +++L+ + D+D+++ +G TPL A + + +LI+ A +
Sbjct: 595 HHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI 642
Score = 55.8 bits (133), Expect = 7e-08
Identities = 38/133 (28%), Positives = 62/133 (46%)
Frame = +1
Query: 178 LDYKNKLGWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXX 357
+D ++K G T LH A G +++ + A+ + G P+H AA G
Sbjct: 365 IDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKL 424
Query: 358 XXXXXXXXXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSY 537
D+ GRT + AA G+ + LLL GAD + +D G +PLH+ A + +Y
Sbjct: 425 LSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNY 484
Query: 538 KGIKILIDNDAYV 576
+ + L+ + A V
Sbjct: 485 QCLFALVGSGASV 497
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +1
Query: 199 GWTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXX 378
G LH A + G + L + + D+FG + +H AA+ G+
Sbjct: 405 GMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADF 464
Query: 379 XXXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDS-YKGIKIL 555
D GR+P+ YAA + + + L+ +GA ++ D G TPLH+ A D+ K ++ L
Sbjct: 465 NKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYL 524
Query: 556 IDNDA 570
+ NDA
Sbjct: 525 LRNDA 529
Score = 45.1 bits (105), Expect = 1e-04
Identities = 23/63 (36%), Positives = 38/63 (60%)
Frame = +1
Query: 388 DNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILIDND 567
DN RTP+ AA G + I++LL+L+GA ++ +D TPLH S + +++L+ +
Sbjct: 71 DNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHS 130
Query: 568 AYV 576
A V
Sbjct: 131 ADV 133
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/119 (25%), Positives = 52/119 (43%)
Frame = +1
Query: 202 WTALHKAVIMGSWKIVSEFLRRSANPNMKDNFGESPIHFAASRGHEXXXXXXXXXXXXXX 381
+ +L +A+ G V + + + N +DN +P+H AA G
Sbjct: 42 YPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVN 101
Query: 382 XXDNSGRTPISYAAQHGHSCIVKLLLLNGADIDIQDLNGNTPLHHLAMHDSYKGIKILI 558
D+ TP+ A V++LL + AD++ +D N TPLH A + + K + L+
Sbjct: 102 AKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALV 160
Score = 44.3 bits (103), Expect = 2e-04
Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 4/136 (2%)
Frame = +1
Query: 112 LFAAIDSGNMDVILFVMSNMINLDYKNKLGWTALHKAVIMGSWKIVSEFLRR-SANPNMK 288
L AA + +++ + ++S+ ++ + G T L A G V + SA ++
Sbjct: 860 LHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQ 919
Query: 289 DNFGESPIHFAASRGHEXXXXXXXXXXXXXXXXDNSG---RTPISYAAQHGHSCIVKLLL 459
DN + +H A S+GHE + + +TP+ AA++G + +V+ LL
Sbjct: 920 DNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELL 979
Query: 460 LNGADIDIQDLNGNTP 507
GA + D NG TP
Sbjct: 980 GKGASVLAVDENGYTP 995
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,087,992
Number of Sequences: 369166
Number of extensions: 1251456
Number of successful extensions: 4659
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2706
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3884
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4275400980
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)