Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_G20
(587 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase) 215 7e-56
sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase) 213 3e-55
sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase) 213 4e-55
sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Hist... 183 2e-46
sp|Q67JH4|HUTH_SYMTH Histidine ammonia-lyase (Histidase) 161 1e-39
sp|Q5WWW8|HUTH_LEGPL Histidine ammonia-lyase (Histidase) 159 4e-39
sp|Q5X5I5|HUTH_LEGPA Histidine ammonia-lyase (Histidase) 159 4e-39
sp|Q5ZVR0|HUTH_LEGPH Histidine ammonia-lyase (Histidase) 159 4e-39
sp|Q5NZX8|HUTH_AZOSE Histidine ammonia-lyase (Histidase) 158 1e-38
sp|Q9RZ06|HUTH_DEIRA Histidine ammonia-lyase (Histidase) 155 9e-38
>sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase)
Length = 657
Score = 215 bits (547), Expect = 7e-56
Identities = 110/174 (63%), Positives = 131/174 (75%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRIERL NP+ S LPAFLV +GG+NSGFM+AH TAAALVSENK L HPSSVDSL+TSA
Sbjct: 469 RRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSENKALCHPSSVDSLSTSAAT 528
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSMG +AARKAL V+ +VE VLAIELLA+ Q +EFLRPLK+T PLE V L+R+ V+
Sbjct: 529 EDHVSMGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVR 588
Query: 361 PWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIENFESYKLPDLWISSPTTTSLK 522
PW KDRFMAPDIE L ++W V P+IE + +P+ SPT SL+
Sbjct: 589 PWIKDRFMAPDIEAAHRLLLEQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLQ 642
>sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase)
Length = 657
Score = 213 bits (542), Expect = 3e-55
Identities = 110/174 (63%), Positives = 131/174 (75%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRIERL NP+ S LPAFLV +GG+NSGFM+AH TAAALVSE+K L HPSSVDSL+TSA
Sbjct: 469 RRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSESKALCHPSSVDSLSTSAAT 528
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSMG +AARKAL VV +VE VLAIELLA+ Q +EFLRPLK+T PLE V L+R+ V+
Sbjct: 529 EDHVSMGGWAARKALRVVEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVR 588
Query: 361 PWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIENFESYKLPDLWISSPTTTSLK 522
PW KDRFMAPDIE L ++W V P+IE + +P+ SPT SL+
Sbjct: 589 PWIKDRFMAPDIEAAHRLLLDQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLE 642
>sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase)
Length = 657
Score = 213 bits (541), Expect = 4e-55
Identities = 109/174 (62%), Positives = 131/174 (75%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRIERL NP+ S LPAFLV +GG+NSGFM+AH TAAALVSE+K L HPSSVDSL+TSA
Sbjct: 469 RRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSESKALCHPSSVDSLSTSAAT 528
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSMG +AARKAL V+ +VE VLAIELLA+ Q +EFLRPLK+T PLE V L+R+ V+
Sbjct: 529 EDHVSMGGWAARKALRVIEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVR 588
Query: 361 PWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIENFESYKLPDLWISSPTTTSLK 522
PW KDRFMAPDIE L ++W V P+IE + +P+ SPT SL+
Sbjct: 589 PWIKDRFMAPDIEAAHRLLLDQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLE 642
>sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Histidase)
Length = 677
Score = 183 bits (465), Expect = 2e-46
Identities = 91/157 (57%), Positives = 115/157 (73%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RR+ERLVN SGLP FL DGG+NSGFM + AA+LVSENKVL HPSSVDS+ TS Q
Sbjct: 485 RRLERLVNKELSGLPTFLTPDGGLNSGFMTVQLCAASLVSENKVLCHPSSVDSIPTSCNQ 544
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSMG FAARKAL VV +VE VLA+ELLA+ Q +EFL+PL ST PL + +L+R+
Sbjct: 545 EDHVSMGGFAARKALTVVEHVEAVLAMELLAACQGIEFLKPLISTAPLHKIYQLVRSVAP 604
Query: 361 PWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIENFES 471
P ++DR+M P+I+ V+ ++ IW V P +E E+
Sbjct: 605 PLNEDRYMKPEIDAVLEMIRENRIWEAVLPHLETLEA 641
>sp|Q67JH4|HUTH_SYMTH Histidine ammonia-lyase (Histidase)
Length = 507
Score = 161 bits (407), Expect = 1e-39
Identities = 85/149 (57%), Positives = 104/149 (69%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRIERLVNP SGLPAFL ++GG++SG M+ TAA+LVSENKVL HP+SVDS+ +SA Q
Sbjct: 352 RRIERLVNPQLSGLPAFLTRNGGVHSGLMITQYTAASLVSENKVLAHPASVDSIPSSANQ 411
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSMG AARKA +V++NV VLAIELL + QALEF+ P + A IR V
Sbjct: 412 EDHVSMGTTAARKARQVIANVRRVLAIELLCAAQALEFVGPERLAPATRAAYAAIRERVA 471
Query: 361 PWDKDRFMAPDIEHVVNTLKAGEIWNVVE 447
P DR +APDIE + + GE+ VE
Sbjct: 472 PLSGDRVLAPDIEALAELVHNGELVAAVE 500
>sp|Q5WWW8|HUTH_LEGPL Histidine ammonia-lyase (Histidase)
Length = 506
Score = 159 bits (403), Expect = 4e-39
Identities = 77/135 (57%), Positives = 102/135 (75%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRI L++ +SGLPAFLV++ G+NSGFM+AHVTAA+ S+NK L HP SVDSL TSA Q
Sbjct: 355 RRIALLIDKNFSGLPAFLVRESGLNSGFMIAHVTAASCASDNKALAHPHSVDSLPTSANQ 414
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSM AAR+ E++ N +LAIELLA+ Q LEF +PLK++ L+ + + +R+ VK
Sbjct: 415 EDHVSMATSAARRLHEMIDNTSTILAIELLAACQGLEFHKPLKTSPQLDKIYQSVRSVVK 474
Query: 361 PWDKDRFMAPDIEHV 405
+DKDR+ APDIE +
Sbjct: 475 EYDKDRYFAPDIEKI 489
>sp|Q5X5I5|HUTH_LEGPA Histidine ammonia-lyase (Histidase)
Length = 506
Score = 159 bits (403), Expect = 4e-39
Identities = 77/135 (57%), Positives = 102/135 (75%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRI L++ +SGLPAFLV++ G+NSGFM+AHVTAA+ S+NK L HP SVDSL TSA Q
Sbjct: 355 RRIALLIDKNFSGLPAFLVRESGLNSGFMIAHVTAASCASDNKALAHPHSVDSLPTSANQ 414
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSM AAR+ E++ N +LAIELLA+ Q LEF +PLK++ L+ + + +R+ VK
Sbjct: 415 EDHVSMATSAARRLHEMIDNTSTILAIELLAACQGLEFHKPLKTSPQLDKIYQSVRSVVK 474
Query: 361 PWDKDRFMAPDIEHV 405
+DKDR+ APDIE +
Sbjct: 475 EYDKDRYFAPDIEKI 489
>sp|Q5ZVR0|HUTH_LEGPH Histidine ammonia-lyase (Histidase)
Length = 506
Score = 159 bits (403), Expect = 4e-39
Identities = 77/135 (57%), Positives = 102/135 (75%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRI L++ +SGLPAFLV++ G+NSGFM+AHVTAA+ S+NK L HP SVDSL TSA Q
Sbjct: 355 RRIALLIDKNFSGLPAFLVRESGLNSGFMIAHVTAASCASDNKALAHPHSVDSLPTSANQ 414
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSM AAR+ E++ N +LAIELLA+ Q LEF +PLK++ L+ + + +R+ VK
Sbjct: 415 EDHVSMATSAARRLHEMIDNTSTILAIELLAACQGLEFHKPLKTSPQLDKIYQSVRSVVK 474
Query: 361 PWDKDRFMAPDIEHV 405
+DKDR+ APDIE +
Sbjct: 475 EYDKDRYFAPDIEKI 489
>sp|Q5NZX8|HUTH_AZOSE Histidine ammonia-lyase (Histidase)
Length = 526
Score = 158 bits (399), Expect = 1e-38
Identities = 81/142 (57%), Positives = 103/142 (72%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RRI L++ SGLP FLV +GG+NSGFM+AHVTAAAL SENK+L HP+SVDSL TSA Q
Sbjct: 354 RRIALLIDATLSGLPPFLVTEGGVNSGFMIAHVTAAALASENKLLAHPASVDSLPTSANQ 413
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSM FAARK E+ N +LAIELLA+ Q +E P +++ L+AV+ LIR+ V
Sbjct: 414 EDHVSMSTFAARKLGELADNTATILAIELLAAAQGVELRAPHRTSPRLQAVLALIRSRVP 473
Query: 361 PWDKDRFMAPDIEHVVNTLKAG 426
+D DR+ APDI + + + AG
Sbjct: 474 HYDIDRYFAPDIASIKDEVSAG 495
>sp|Q9RZ06|HUTH_DEIRA Histidine ammonia-lyase (Histidase)
Length = 524
Score = 155 bits (391), Expect = 9e-38
Identities = 86/173 (49%), Positives = 117/173 (67%), Gaps = 1/173 (0%)
Frame = +1
Query: 1 RRIERLVNPAYSGLPAFLVKDGGINSGFMLAHVTAAALVSENKVLTHPSSVDSLTTSAGQ 180
RR E+L+NPA SGLPAFL +GG+NSGFM+A T+AALVSENKVL+HP+SVDS+ TSA Q
Sbjct: 351 RRTEQLLNPALSGLPAFLTPNGGLNSGFMIAQYTSAALVSENKVLSHPASVDSIPTSANQ 410
Query: 181 EDHVSMGAFAARKALEVVSNVENVLAIELLASVQALEFLRPLKSTEPLEAVVRLIRTTVK 360
EDHVSMGA AAR+ ++V+NV+ VL+IELL + Q L+F + L++ ++A +RT V
Sbjct: 411 EDHVSMGAHAARQLRQIVANVQTVLSIELLCAAQGLDF-QQLRAGRGVQAAYEYVRTFVP 469
Query: 361 PWDKDRFMAPDIEHVVNTLKAGEIWNVVEPFIENFES-YKLPDLWISSPTTTS 516
+DR+ PD+ + L +GE+ V + + KLPD TTS
Sbjct: 470 TLTEDRYFRPDLLRLRGELVSGELLRVAQAADTQAPAPAKLPDSGDEDRDTTS 522
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.131 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,603,716
Number of Sequences: 369166
Number of extensions: 1356981
Number of successful extensions: 3916
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3773
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3898
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4406202450
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)