Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_G18
(578 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle 170 3e-42
sp|P05661|MYSA_DROME Myosin heavy chain, muscle 167 2e-41
sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B... 144 2e-34
sp|P02565|MYH3_CHICK Myosin heavy chain, fast skeletal musc... 138 1e-32
sp|Q5SX40|MYH1_MOUSE Myosin-1 (Myosin heavy chain, skeletal... 137 1e-32
sp|P04462|MYH8_RAT Myosin-8 (Myosin heavy chain, skeletal m... 137 2e-32
sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle alp... 137 2e-32
sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, a... 136 3e-32
sp|P13542|MYH8_MOUSE Myosin-8 (Myosin heavy chain, skeletal... 135 6e-32
sp|P12882|MYH1_HUMAN Myosin-1 (Myosin heavy chain, skeletal... 135 6e-32
>sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle
Length = 1938
Score = 170 bits (430), Expect = 3e-42
Identities = 85/131 (64%), Positives = 106/131 (80%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+ ELE ELD EQ+RH ETQKN RK DRRLKE+ +Q DED+KNQ+R+Q+LI+ L AKIKT
Sbjct: 1815 RVHELEAELDNEQRRHAETQKNMRKADRRLKELAFQADEDRKNQERLQELIDKLNAKIKT 1874
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNRGASMG 419
+KRQVEEAEEIAA+NLAKYRK Q E+E++EERAD A+ LQK RAK+RSSVSV R
Sbjct: 1875 FKRQVEEAEEIAAINLAKYRKAQHELEEAEERADTADSTLQKFRAKSRSSVSVQR----- 1929
Query: 420 PGTKISITASS 452
+ +S++AS+
Sbjct: 1930 --SSVSVSASN 1938
Score = 48.9 bits (115), Expect = 9e-06
Identities = 32/106 (30%), Positives = 57/106 (53%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
RI ELE EL+ E+ + +K + +R L+E+ ++DE +L + +A++
Sbjct: 1111 RIEELEEELEAERNARAKVEKQRAELNRELEELGERLDEAGGATSAQIELNKKREAELLK 1170
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAK 377
+R +EEA ++ RK Q+ + E ADQ +Q LQK+++K
Sbjct: 1171 IRRDLEEASLQHEAQISALRKKHQDA--ANEMADQVDQ-LQKVKSK 1213
Score = 42.4 bits (98), Expect = 8e-04
Identities = 22/98 (22%), Positives = 57/98 (58%), Gaps = 1/98 (1%)
Frame = +3
Query: 57 QRIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIK 236
Q ++ + ++ ++ E ++N R+ + + + ++++++ ++Q+ I+ LQA+I+
Sbjct: 1054 QDLKSTQENVEDLERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIE 1113
Query: 237 TYKRQVEEAEEIAAVNLAKYR-KIQQEIEDSEERADQA 347
+ ++ EAE A + K R ++ +E+E+ ER D+A
Sbjct: 1114 ELEEEL-EAERNARAKVEKQRAELNRELEELGERLDEA 1150
Score = 40.4 bits (93), Expect = 0.003
Identities = 20/106 (18%), Positives = 57/106 (53%)
Frame = +3
Query: 69 ELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKR 248
+LE ++ K ++K ++ + ++ ++ ++++ +++ + +Q LQA+ R
Sbjct: 1227 DLESQMTHNMKNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAENSDLTR 1286
Query: 249 QVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRS 386
Q+E+AE +V + ++ ++ED+ ++ +A KL+ + R+
Sbjct: 1287 QLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEETRARSKLQNEVRN 1332
Score = 39.7 bits (91), Expect = 0.005
Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 9/107 (8%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQID-------EDKKNQDRMQQLIENL 221
+ ++ L+ E K + + +K ++ + E+ +D E +K R QQ I +
Sbjct: 1591 LESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQQQIREM 1650
Query: 222 QAKIKTYKRQVEEAEEIAAVNLAKYR--KIQQEIEDSEERADQAEQA 356
Q I+ +RQ +EA E + N+A+ R + E+E+ +QAE+A
Sbjct: 1651 QTSIEEEQRQRDEARE--SYNMAERRCTLMSGEVEELRAALEQAERA 1695
Score = 35.0 bits (79), Expect = 0.13
Identities = 23/104 (22%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
Frame = +3
Query: 81 ELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQ-DRMQQLIENLQAKIKTYKRQVE 257
+L+ EQ+ + Q+ K + +++ + + + N+ + ++ L K+ ++ E
Sbjct: 1343 QLEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTE 1402
Query: 258 EAE-EIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRS 386
A + +A+ AK R +QQE+ED D+A ++ ++ K R+
Sbjct: 1403 AANAKCSALEKAKSR-LQQELEDMSIEVDRANASVNQMEKKQRA 1445
Score = 32.0 bits (71), Expect = 1.1
Identities = 22/92 (23%), Positives = 50/92 (54%), Gaps = 1/92 (1%)
Frame = +3
Query: 81 ELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKRQVEE 260
E+ GE K E K A + RL + + ++D NQ ++++ +NL++++K ++ +++E
Sbjct: 1740 EMHGELKGADERCKKAMADAARLAD-ELRAEQDHSNQ--VEKVRKNLESQVKEFQIRLDE 1796
Query: 261 AEEIAAVNLAK-YRKIQQEIEDSEERADQAEQ 353
AE + K +K++ + + E D ++
Sbjct: 1797 AEASSLKGGKKMIQKLESRVHELEAELDNEQR 1828
Score = 30.4 bits (67), Expect = 3.3
Identities = 15/102 (14%), Positives = 54/102 (52%)
Frame = +3
Query: 75 EGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKRQV 254
E ++ +K+H + +L+++ ++++DKK+ +++ +++L++++ +
Sbjct: 1183 EAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKD---LKREMDDLESQMTHNMKNK 1239
Query: 255 EEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKN 380
+E++ ++ + +EDS+ ++ + +L+A+N
Sbjct: 1240 GCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAEN 1281
Score = 28.9 bits (63), Expect = 9.6
Identities = 22/106 (20%), Positives = 51/106 (48%), Gaps = 7/106 (6%)
Frame = +3
Query: 81 ELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKRQVEE 260
+L+G +K+ N +K+ L+ + ++DK ++D +I T + ++ +
Sbjct: 932 DLEGIKKKMEADNANLKKDIGDLENTLQKAEQDKAHKDN----------QISTLQGEISQ 981
Query: 261 AEEIAAVNLAKYRKIQQEIEDSEERADQAEQA-------LQKLRAK 377
+E ++ K K ++ +E++ ++ + QA L KL+AK
Sbjct: 982 QDE----HIGKLNKEKKALEEANKKTSDSLQAEEDKCNHLNKLKAK 1023
>sp|P05661|MYSA_DROME Myosin heavy chain, muscle
Length = 1962
Score = 167 bits (423), Expect = 2e-41
Identities = 81/122 (66%), Positives = 103/122 (84%)
Frame = +3
Query: 57 QRIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIK 236
QR+RELE ELDGEQ+RH + QKN RK++RR+KE+++Q +ED+KN +RMQ L++ LQ KIK
Sbjct: 1816 QRVRELENELDGEQRRHADAQKNLRKSERRVKELSFQSEEDRKNHERMQDLVDKLQQKIK 1875
Query: 237 TYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNRGASM 416
TYKRQ+EEAEEIAA+NLAK+RK QQE+E++EERAD AEQA+ K RAK R+ SV RGAS
Sbjct: 1876 TYKRQIEEAEEIAALNLAKFRKAQQELEEAEERADLAEQAISKFRAKGRAG-SVGRGASP 1934
Query: 417 GP 422
P
Sbjct: 1935 AP 1936
Score = 47.0 bits (110), Expect = 3e-05
Identities = 25/107 (23%), Positives = 55/107 (51%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
I ELE LD K + E QKN ++ ++LK+I ++E+++ +D ++ + + +
Sbjct: 1621 INELEIALDHANKANAEAQKNIKRYQQQLKDIQTALEEEQRARDDAREQLGISERRANAL 1680
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
+ ++EE+ + R+ +QE+ D+ E+ ++ + A R
Sbjct: 1681 QNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKR 1727
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 7/101 (6%)
Frame = +3
Query: 66 RELEGELDGEQKRHVETQKNAR-------KNDRRLKEITYQIDEDKKNQDRMQQLIENLQ 224
R++EG+L Q+ + ++N + + D+ L IT ++++++ + Q+ I+ LQ
Sbjct: 1052 RKVEGDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAKLEDEQVVVLKHQRQIKELQ 1111
Query: 225 AKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQA 347
A+I+ + +VE + A + + +E+E+ ER ++A
Sbjct: 1112 ARIEELEEEVEAERQARAKAEKQRADLARELEELGERLEEA 1152
Score = 31.2 bits (69), Expect = 1.9
Identities = 23/102 (22%), Positives = 50/102 (49%), Gaps = 4/102 (3%)
Frame = +3
Query: 63 IRELEGELDGEQKR----HVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAK 230
+ E E L+ E+ + +E + ++ DRR++E + + +KN Q+ ++++QA
Sbjct: 1543 LEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEEEFENTRKNH---QRALDSMQAS 1599
Query: 231 IKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 356
++ + EA L +K++ +I + E D A +A
Sbjct: 1600 LEAEAKGKAEA-------LRMKKKLEADINELEIALDHANKA 1634
Score = 30.4 bits (67), Expect = 3.3
Identities = 22/91 (24%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Frame = +3
Query: 117 QKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKRQVEEAEEIAAVNLAKY 296
+K A++ L E+ ++DE + + + L + RQ+EEAE + L+K
Sbjct: 1245 EKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEEAESQVS-QLSKI 1303
Query: 297 R-KIQQEIEDSEERADQAEQALQKLRAKNRS 386
+ + ++ED++ AD+ + L K R+
Sbjct: 1304 KISLTTQLEDTKRLADEESRERATLLGKFRN 1334
>sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated protein 54)
Length = 1966
Score = 144 bits (362), Expect = 2e-34
Identities = 70/131 (53%), Positives = 101/131 (77%)
Frame = +3
Query: 57 QRIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIK 236
QR+RELE ELDGEQ+R + KN + DRR++E+ +Q+DEDKKN +R+Q LI+ LQ K+K
Sbjct: 1829 QRVRELESELDGEQRRFQDANKNLGRADRRVRELQFQVDEDKKNFERLQDLIDKLQQKLK 1888
Query: 237 TYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNRGASM 416
T K+QVEEAEE+A +NL KY+++ ++ED+EERADQAE +L K+R+K+R+S AS+
Sbjct: 1889 TQKKQVEEAEELANLNLQKYKQLTHQLEDAEERADQAENSLSKMRSKSRAS------ASV 1942
Query: 417 GPGTKISITAS 449
PG + S +A+
Sbjct: 1943 APGLQSSASAA 1953
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/98 (26%), Positives = 50/98 (51%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
I ELE LD K + + QKN ++ +++E+ Q++E+++N ++ N + +
Sbjct: 1634 INELEIALDHANKANADAQKNLKRYQEQVRELQLQVEEEQRNGADTREQFFNAEKRATLL 1693
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 356
+ E EE+ N A R +Q ++ + DQA +A
Sbjct: 1694 Q---SEKEELLVANEAAERARKQAEYEAADARDQANEA 1728
Score = 39.3 bits (90), Expect = 0.007
Identities = 36/158 (22%), Positives = 69/158 (43%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
RI ELE EL+ E++ + + R L+E+ ++DE ++ + +A++
Sbjct: 1126 RISELEEELENERQSRSKADRAKSDLQRELEELGEKLDEQGGATAAQVEVNKKREAELAK 1185
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNRGASMG 419
+R +EEA L RK + + E DQ +Q L K +AK V ++ ++
Sbjct: 1186 LRRDLEEANMNHENQLGGLRK--KHTDAVAELTDQLDQ-LNKAKAK----VEKDKAQAVR 1238
Query: 420 PGTKISITASSRTED*LDGKEIFKNFYK*LANISLRLD 533
++ T L+ +++ K F L + + D
Sbjct: 1239 DAEDLAAQLDQETSGKLNNEKLAKQFELQLTELQSKAD 1276
Score = 33.9 bits (76), Expect = 0.30
Identities = 22/112 (19%), Positives = 56/112 (50%), Gaps = 7/112 (6%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDED---KKNQDRMQQLIE----NL 221
+ EL +LD K + +K+ + R +++ Q+D++ K N +++ + E L
Sbjct: 1212 VAELTDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLNNEKLAKQFELQLTEL 1271
Query: 222 QAKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAK 377
Q+K RQ+++ + ++ + +++ED+E + +Q + +L ++
Sbjct: 1272 QSKADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAESQVNQLTRLKSQLTSQ 1323
>sp|P02565|MYH3_CHICK Myosin heavy chain, fast skeletal muscle, embryonic
Length = 1940
Score = 138 bits (347), Expect = 1e-32
Identities = 66/108 (61%), Positives = 87/108 (80%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+RELEGE+D EQKR E K RK +RR+KE+TYQ +ED+KN R+Q L++ LQ K+K+
Sbjct: 1823 RVRELEGEVDAEQKRSAEAVKGVRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQMKVKS 1882
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
YKRQ EEAEE++ VNL+K+RKIQ E+E++EERAD AE + KLRAK+R
Sbjct: 1883 YKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRAKSR 1930
Score = 45.4 bits (106), Expect = 1e-04
Identities = 25/113 (22%), Positives = 55/113 (48%)
Frame = +3
Query: 66 RELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYK 245
R+LEG+L Q+ ++ + + ++ D +LK+ ++I + + + Q L LQ KIK +
Sbjct: 1058 RKLEGDLKMTQESTMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1117
Query: 246 RQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
++EE EE K ++ D ++ + L++ + + +N+
Sbjct: 1118 ARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIDMNK 1170
Score = 40.4 bits (93), Expect = 0.003
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Frame = +3
Query: 132 KNDRRLKEITYQIDEDKKNQDRMQQLIEN---LQAKIKTYKRQVEEAEEIAAVNLAKYRK 302
KND +L ++ + D ++R QLI+ L+AKIK + E+ EE+ A AK RK
Sbjct: 889 KNDLQL-QVQAEADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKRK 947
Query: 303 IQQEIEDSEERADQAEQALQKLRAKNRSS 389
++ E + ++ D E L K+ + ++
Sbjct: 948 LEDECSELKKDIDDLELTLAKVEKEKHAT 976
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/114 (20%), Positives = 53/114 (46%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
+ E+E +L ++ E QKN R LK+ +D+ ++Q+ +++ + ++ +
Sbjct: 1627 LNEIEIQLSHANRQAAEAQKNLRNTQGVLKDTQIHLDDALRSQEDLKEQVAMVERRANLL 1686
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
+ ++EE + +QE+ D+ ER +Q L +N S ++ +
Sbjct: 1687 QAEIEELRAALEQTERSRKVAEQELLDASER-------VQLLHTQNTSLINTKK 1733
Score = 32.7 bits (73), Expect = 0.67
Identities = 21/98 (21%), Positives = 44/98 (44%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
I +L ++ K +K R + +L EI + +E ++ + + LQ + Y
Sbjct: 1233 IDDLASNMESVSKAKANLEKMCRSLEDQLSEIKTKEEEQQRTINDISAQKARLQTESGEY 1292
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 356
RQVEE + + + + Q+IE+ + ++ +A
Sbjct: 1293 SRQVEEKDALISQLSRGKQAFTQQIEELKRHLEEEIKA 1330
Score = 30.4 bits (67), Expect = 3.3
Identities = 23/108 (21%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Frame = +3
Query: 69 ELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIE---NLQAKIKT 239
E E E+ ++ +T++ K++ + KE+ +++M L++ +LQ +++
Sbjct: 849 ESEKEMANMKEEFEKTKEELAKSEAKRKEL----------EEKMVSLLQEKNDLQLQVQA 898
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
+ +AEE + +++ +I++ ERA+ E+ +L AK R
Sbjct: 899 EADGLADAEERCDQLIKTKIQLEAKIKELTERAEDEEEMNAELTAKKR 946
Score = 30.0 bits (66), Expect = 4.3
Identities = 26/122 (21%), Positives = 52/122 (42%), Gaps = 5/122 (4%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
+I+EL + E++ + E RK + E+ ID+ + ++++ + K+K
Sbjct: 923 KIKELTERAEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 982
Query: 240 YKRQVEEAEEIAAVNLAKYRKI-----QQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
++ +E A L K +K QQ ++D + D+ L K + K V
Sbjct: 983 LTEEMAALDETIA-KLTKEKKALQEAHQQTLDDLQAEEDKV-NTLTKAKTKLEQQVDDLE 1040
Query: 405 GA 410
G+
Sbjct: 1041 GS 1042
>sp|Q5SX40|MYH1_MOUSE Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1)
Length = 1942
Score = 137 bits (346), Expect = 1e-32
Identities = 66/108 (61%), Positives = 88/108 (81%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+RELEGE++ EQKR+VE K RK++RR+KE+TYQ +ED+KN R+Q L++ LQ+K+K
Sbjct: 1825 RVRELEGEVENEQKRNVEAIKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQSKVKA 1884
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
YKRQ EEAEE + VNLAK+RKIQ E+E++EERAD AE + KLR K+R
Sbjct: 1885 YKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIAESQVNKLRVKSR 1932
Score = 45.8 bits (107), Expect = 8e-05
Identities = 25/113 (22%), Positives = 56/113 (49%)
Frame = +3
Query: 66 RELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYK 245
R+LEG+L Q+ ++ + + ++ D +LK+ +++ + + Q L LQ KIK +
Sbjct: 1060 RKLEGDLKLAQESTMDVENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQLQKKIKELQ 1119
Query: 246 RQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
++EE EE A K +++ D ++ + L++ + + +N+
Sbjct: 1120 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1172
Score = 42.4 bits (98), Expect = 8e-04
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Frame = +3
Query: 132 KNDRRLKEITYQIDEDKKNQDRMQQLIEN---LQAKIKTYKRQVEEAEEIAAVNLAKYRK 302
KND +L ++ + D ++R QLI+ L+AKIK + E+ EEI A AK RK
Sbjct: 891 KNDLQL-QVQSEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRK 949
Query: 303 IQQEIEDSEERADQAEQALQKLRAKNRSS 389
++ E + ++ D E L K+ + ++
Sbjct: 950 LEDECSELKKDIDDLELTLAKVEKEKHAT 978
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/107 (23%), Positives = 60/107 (56%), Gaps = 12/107 (11%)
Frame = +3
Query: 81 ELDGEQKRHVETQKNARKNDRR-LKEITYQIDEDKKNQD---RMQQLIENLQAKIKTYKR 248
++ GE + V+ +NA + ++ + + +E KK QD ++++ +NL+ +K +
Sbjct: 1743 QIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1802
Query: 249 QVEEAEEIAAVN--------LAKYRKIQQEIEDSEERADQAEQALQK 365
+++EAE++A A+ R+++ E+E+ ++R +A + L+K
Sbjct: 1803 RLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNVEAIKGLRK 1849
Score = 35.0 bits (79), Expect = 0.13
Identities = 21/114 (18%), Positives = 51/114 (44%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
+ E+E +L+ + E +N R LK+ +D+ + Q+ +++ + ++ +
Sbjct: 1629 LNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLL 1688
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
+ ++EE + +QE+ D+ ER +Q L +N S ++ +
Sbjct: 1689 QAEIEELRATLEQTERSRKIAEQELLDASER-------VQLLHTQNTSLINTKK 1735
Score = 31.2 bits (69), Expect = 1.9
Identities = 28/125 (22%), Positives = 60/125 (48%), Gaps = 22/125 (17%)
Frame = +3
Query: 63 IRELEGELDGEQKR--HVETQKNARKN--DRRLKEITYQIDEDKKNQDRMQQLIEN-LQA 227
+ E E L+ E+ + ++ + N K+ DR++ E +ID+ K+N R+ + +++ L A
Sbjct: 1551 LEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDA 1610
Query: 228 KIKT-----------------YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 356
+I++ + Q+ + +AA L YR Q ++D++ D A +
Sbjct: 1611 EIRSRNDAIRLKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHLDDALRG 1670
Query: 357 LQKLR 371
+ L+
Sbjct: 1671 QEDLK 1675
Score = 30.8 bits (68), Expect = 2.5
Identities = 22/105 (20%), Positives = 51/105 (48%)
Frame = +3
Query: 69 ELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKR 248
E E E+ ++ + ++N K + + KE+ ++ + Q +LQ ++++
Sbjct: 851 ETEKEMANMKEEFEKAKENLAKAEAKRKEL-------EEKMVALMQEKNDLQLQVQSEAD 903
Query: 249 QVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
+ +AEE + +++ +I++ ERA+ E+ +L AK R
Sbjct: 904 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 948
Score = 30.4 bits (67), Expect = 3.3
Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 3/144 (2%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
++ EL+ + + +Q+ E + E + Q+DE ++ + + +I+
Sbjct: 1262 QVSELKTKEEEQQRLINELTAQRGRLQTESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEE 1321
Query: 240 YKRQVEE---AEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNRGA 410
KRQ+EE A+ A L R + + E +A+ LQ+ +K S V+ R
Sbjct: 1322 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWR-- 1379
Query: 411 SMGPGTKISITASSRTED*LDGKE 482
TK A RTE+ + K+
Sbjct: 1380 -----TKYETDAIQRTEELEEAKK 1398
>sp|P04462|MYH8_RAT Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
(MyHC-perinatal)
Length = 257
Score = 137 bits (345), Expect = 2e-32
Identities = 65/108 (60%), Positives = 88/108 (81%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+RELEGE++ EQKR+ E K RK++RR+KE+TYQ +ED+KN R+Q L++ LQAK+K+
Sbjct: 141 RVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKS 200
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
YKRQ EEAEE + VNLAK+RK+Q E+E++EERAD AE + KLR K+R
Sbjct: 201 YKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 248
>sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1939
Score = 137 bits (345), Expect = 2e-32
Identities = 65/108 (60%), Positives = 87/108 (80%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+RELEGEL+ EQKR+ E+ K RK++RR+KE+TYQ +EDKKN R+Q L++ LQ K+K
Sbjct: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKA 1879
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
YKRQ EEAEE A NL+K+RK+Q E++++EERAD AE + KLRAK+R
Sbjct: 1880 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/117 (29%), Positives = 61/117 (52%), Gaps = 7/117 (5%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNA--RKNDRRLKEITYQIDEDKKN--QDRMQQLIEN--- 218
RI+E + + +K E + KND +L+ Q ++D N ++R QLI+N
Sbjct: 860 RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQ---VQAEQDNLNDAEERCDQLIKNKIQ 916
Query: 219 LQAKIKTYKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSS 389
L+AK+K ++E+ EE+ A AK RK++ E + ++ D E L K+ + ++
Sbjct: 917 LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 973
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/101 (26%), Positives = 53/101 (52%), Gaps = 7/101 (6%)
Frame = +3
Query: 66 RELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYK 245
R+LEG+L Q+ ++ + + + + +LK+ + I++ + Q L LQ K+K +
Sbjct: 1055 RKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQ 1114
Query: 246 RQVE------EAEEIAAVNLAKYRK-IQQEIEDSEERADQA 347
++E EAE A + K R + +E+E+ ER ++A
Sbjct: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEA 1155
Score = 34.7 bits (78), Expect = 0.18
Identities = 22/111 (19%), Positives = 51/111 (45%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
+ E+E +L + E QK + LK+ Q+D+ + D +++ I ++ +
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVS 395
+ ++EE + + +QE+ ++ ER +Q L ++N S ++
Sbjct: 1684 QAELEELRAVVEQTERSRKLAEQELIETSER-------VQLLHSQNTSLIN 1727
Score = 33.9 bits (76), Expect = 0.30
Identities = 23/115 (20%), Positives = 54/115 (46%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
+++E+ L+ E++ + E RK + E+ ID+ + ++++ + K+K
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 979
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
++ +EI A L K +K QE ++ D + K+ + ++S V + +
Sbjct: 980 LTEEMAGLDEIIA-KLTKEKKALQEAH--QQALDDLQVEEDKVNSLSKSKVKLEQ 1031
Score = 30.4 bits (67), Expect = 3.3
Identities = 18/102 (17%), Positives = 49/102 (48%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
+ EL ++D Q+ + +K + L ++T +++ K + ++++ L+ + Y
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKL 368
+ ++EEA+ + K+Q E + + ++ E + +L
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
>sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, adult
Length = 1939
Score = 136 bits (343), Expect = 3e-32
Identities = 65/108 (60%), Positives = 86/108 (79%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+RELEGE+D EQKR E K RK +RR+KE+TYQ +ED+KN R+Q L++ LQ K+K+
Sbjct: 1821 RVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKLQMKVKS 1880
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
YKRQ EEAEE++ VNL+K+RKIQ E+E++EERAD AE + KLR K+R
Sbjct: 1881 YKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSR 1928
Score = 42.4 bits (98), Expect = 8e-04
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Frame = +3
Query: 132 KNDRRLKEITYQIDEDKKNQDRMQQLIEN---LQAKIKTYKRQVEEAEEIAAVNLAKYRK 302
KND +L ++ + D ++R QLI+ L+AKIK + E+ EEI A AK RK
Sbjct: 887 KNDLQL-QVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRK 945
Query: 303 IQQEIEDSEERADQAEQALQKLRAKNRSS 389
++ E + ++ D E L K+ + ++
Sbjct: 946 LEDECSELKKDIDDLELTLAKVEKEKHAT 974
Score = 42.0 bits (97), Expect = 0.001
Identities = 24/113 (21%), Positives = 53/113 (46%)
Frame = +3
Query: 66 RELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYK 245
R+LEG+L ++ + + ++ D +LK+ ++I + + + Q L LQ KIK +
Sbjct: 1056 RKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQ 1115
Query: 246 RQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
++EE EE K ++ D ++ + L++ + + +N+
Sbjct: 1116 ARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIEMNK 1168
Score = 39.7 bits (91), Expect = 0.005
Identities = 24/114 (21%), Positives = 51/114 (44%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
+ E+E +L + E QKN R LK+ +D+ + Q+ +++ + ++ +
Sbjct: 1625 LNEMEIQLSHANRMAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLL 1684
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
+ +VEE + +QE+ D+ ER +Q L +N S ++ +
Sbjct: 1685 QAEVEELRGALEQTERSRKVAEQELLDATER-------VQLLHTQNTSLINTKK 1731
>sp|P13542|MYH8_MOUSE Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
(MyHC-perinatal)
Length = 1937
Score = 135 bits (341), Expect = 6e-32
Identities = 64/108 (59%), Positives = 87/108 (80%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+RELEGE++ EQKR+ E K RK++RR+KE+TYQ +ED+KN R+Q L++ LQAK+K+
Sbjct: 1821 RVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKS 1880
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
YKRQ EEAEE + NLAK+RK+Q E+E++EERAD AE + KLR K+R
Sbjct: 1881 YKRQAEEAEEQSNANLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Frame = +3
Query: 132 KNDRRLKEITYQIDEDKKNQDRMQQLIEN---LQAKIKTYKRQVEEAEEIAAVNLAKYRK 302
KND +L ++ + D ++R +QLI+N L+AKIK + E+ EEI A AK RK
Sbjct: 887 KNDLQL-QVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRK 945
Query: 303 IQQEIEDSEERADQAEQALQKLRAKNRSS 389
++ E + ++ D E L K+ + ++
Sbjct: 946 LEDECSELKKDIDDLELTLAKVEKEKHAT 974
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/113 (23%), Positives = 55/113 (48%)
Frame = +3
Query: 66 RELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYK 245
R+LEG+L Q+ ++ + + ++ D +LK+ ++I + Q + LQ KIK +
Sbjct: 1056 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
Query: 246 RQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
++EE EE A K +++ D ++ + L++ + V +N+
Sbjct: 1116 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVEMNK 1168
Score = 34.3 bits (77), Expect = 0.23
Identities = 29/125 (23%), Positives = 61/125 (48%), Gaps = 22/125 (17%)
Frame = +3
Query: 63 IRELEGELDGEQKR--HVETQKNARKN--DRRLKEITYQIDEDKKNQDRMQQLIEN-LQA 227
+ E E L+ E+ + ++ + N K+ DR++ E +ID+ K+N R+ + +++ L A
Sbjct: 1547 LEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHVRVVETMQSTLDA 1606
Query: 228 KIKT-----------------YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 356
+I++ + Q+ A +AA +L YR Q ++D++ D A +
Sbjct: 1607 EIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRG 1666
Query: 357 LQKLR 371
+ L+
Sbjct: 1667 QEDLK 1671
Score = 34.3 bits (77), Expect = 0.23
Identities = 21/114 (18%), Positives = 52/114 (45%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
+ E+E +L+ + E+ +N R LK+ +D+ + Q+ +++ + ++ +
Sbjct: 1625 LNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAIVERRANLL 1684
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
+ ++EE + +QE+ D+ ER +Q L +N S ++ +
Sbjct: 1685 QAEIEELRATLEQTERSRKIAEQELLDASER-------VQLLHTQNTSLINTKK 1731
Score = 29.6 bits (65), Expect = 5.6
Identities = 32/144 (22%), Positives = 60/144 (41%), Gaps = 3/144 (2%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
++ EL+ + + +Q+ E + E + Q+DE ++ + + +I+
Sbjct: 1258 QVSELKSKEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEE 1317
Query: 240 YKRQVEE---AEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNRGA 410
KRQ+EE A+ A L R + + E + + LQ+ +K S V+ R
Sbjct: 1318 LKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR-- 1375
Query: 411 SMGPGTKISITASSRTED*LDGKE 482
TK A RTE+ + K+
Sbjct: 1376 -----TKYETDAIQRTEELEEAKK 1394
Score = 28.9 bits (63), Expect = 9.6
Identities = 22/107 (20%), Positives = 50/107 (46%), Gaps = 7/107 (6%)
Frame = +3
Query: 90 GEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKRQV----- 254
GEQ +++ K +K ++ E+ +ID+ N + + + NL+ +T + QV
Sbjct: 1207 GEQIDNLQRVK--QKLEKEKSELKMEIDDLSSNAEAIAKAKGNLEKMCRTLEDQVSELKS 1264
Query: 255 --EEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSS 389
EE + + A+ ++Q E + + D+ + + +L ++S
Sbjct: 1265 KEEEQQRLINELTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAS 1311
>sp|P12882|MYH1_HUMAN Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy
chain IIx/d) (MyHC-IIx/d)
Length = 1939
Score = 135 bits (341), Expect = 6e-32
Identities = 64/108 (59%), Positives = 89/108 (82%)
Frame = +3
Query: 60 RIRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKT 239
R+RELEGE++ EQKR+VE K RK++R++KE+TYQ +ED+KN R+Q L++ LQAK+K+
Sbjct: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
Query: 240 YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
YKRQ EEAEE + VNL+K+R+IQ E+E++EERAD AE + KLR K+R
Sbjct: 1882 YKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
Score = 44.7 bits (104), Expect = 2e-04
Identities = 25/113 (22%), Positives = 56/113 (49%)
Frame = +3
Query: 66 RELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYK 245
R+LEG+L Q+ ++ + + ++ D +LK+ +++ + + Q L LQ KIK +
Sbjct: 1057 RKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116
Query: 246 RQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
++EE EE A K +++ D ++ + L++ + + +N+
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1169
Score = 42.4 bits (98), Expect = 8e-04
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
Frame = +3
Query: 132 KNDRRLKEITYQIDEDKKNQDRMQQLIEN---LQAKIKTYKRQVEEAEEIAAVNLAKYRK 302
KND +L ++ + D ++R QLI+ L+AKIK + E+ EEI A AK RK
Sbjct: 888 KNDLQL-QVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRK 946
Query: 303 IQQEIEDSEERADQAEQALQKLRAKNRSS 389
++ E + ++ D E L K+ + ++
Sbjct: 947 LEDECSELKKDIDDLELTLAKVEKEKHAT 975
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/111 (22%), Positives = 60/111 (54%), Gaps = 12/111 (10%)
Frame = +3
Query: 81 ELDGEQKRHVETQKNARKNDRR-LKEITYQIDEDKKNQD---RMQQLIENLQAKIKTYKR 248
++ GE + ++ +NA + ++ + + +E KK QD ++++ +NL+ +K +
Sbjct: 1740 QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Query: 249 QVEEAEEIAAVN--------LAKYRKIQQEIEDSEERADQAEQALQKLRAK 377
+++EAE++A A+ R+++ E+E ++R +A + L+K K
Sbjct: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERK 1850
Score = 35.4 bits (80), Expect = 0.10
Identities = 21/114 (18%), Positives = 52/114 (45%)
Frame = +3
Query: 63 IRELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTY 242
+ E+E +L+ + E +N R LK+ +D+ ++Q+ +++ + ++ +
Sbjct: 1626 LNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLL 1685
Query: 243 KRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNRSSVSVNR 404
+ ++EE + +QE+ D+ ER +Q L +N S ++ +
Sbjct: 1686 QAEIEELRATLEQTERSRKIAEQELLDASER-------VQLLHTQNTSLINTKK 1732
Score = 33.5 bits (75), Expect = 0.39
Identities = 29/125 (23%), Positives = 61/125 (48%), Gaps = 22/125 (17%)
Frame = +3
Query: 63 IRELEGELDGEQKR--HVETQKNARKN--DRRLKEITYQIDEDKKNQDRMQQLIEN-LQA 227
+ E E L+ E+ + ++ + N K+ DR++ E +ID+ K+N R+ + +++ L A
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDA 1607
Query: 228 KIKT-----------------YKRQVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQA 356
+I++ + Q+ A +AA L YR Q ++D++ D A ++
Sbjct: 1608 EIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRS 1667
Query: 357 LQKLR 371
+ L+
Sbjct: 1668 QEDLK 1672
Score = 31.2 bits (69), Expect = 1.9
Identities = 24/105 (22%), Positives = 52/105 (49%)
Frame = +3
Query: 69 ELEGELDGEQKRHVETQKNARKNDRRLKEITYQIDEDKKNQDRMQQLIENLQAKIKTYKR 248
E E E+ ++ +T++ K + + KE+ ++K MQ+ +LQ +++
Sbjct: 848 ETEKEMANMKEEFEKTKEELAKTEAKRKEL------EEKMVTLMQEK-NDLQLQVQAEAD 900
Query: 249 QVEEAEEIAAVNLAKYRKIQQEIEDSEERADQAEQALQKLRAKNR 383
+ +AEE + +++ +I++ ERA+ E+ +L AK R
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKR 945
Score = 28.9 bits (63), Expect = 9.6
Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 3/113 (2%)
Frame = +3
Query: 153 EITYQIDEDKKNQDRMQQLIENLQAKIKTYKRQVEE---AEEIAAVNLAKYRKIQQEIED 323
E + Q+DE ++ + + +I+ KRQ+EE A+ A L R + +
Sbjct: 1290 EYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLRE 1349
Query: 324 SEERADQAEQALQKLRAKNRSSVSVNRGASMGPGTKISITASSRTED*LDGKE 482
E +A+ LQ+ +K S V+ R TK A RTE+ + K+
Sbjct: 1350 QYEEEQEAKAELQRAMSKANSEVAQWR-------TKYETDAIQRTEELEEAKK 1395
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,114,104
Number of Sequences: 369166
Number of extensions: 845169
Number of successful extensions: 5569
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4413
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5392
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4259329035
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)