Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_E18
(844 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q12926|ELAV2_HUMAN ELAV-like protein 2 (Hu-antigen B) (H... 184 3e-46
sp|Q60899|ELAV2_MOUSE ELAV-like protein 2 (Hu-antigen B) (H... 183 6e-46
sp|P26378|ELAV4_HUMAN ELAV-like protein 4 (Paraneoplastic e... 181 3e-45
sp|O09032|ELAV4_RAT ELAV-like protein 4 (Paraneoplastic enc... 180 4e-45
sp|Q61701|ELAV4_MOUSE ELAV-like protein 4 (Paraneoplastic e... 180 4e-45
sp|Q14576|ELAV3_HUMAN ELAV-like protein 3 (Hu-antigen C) (H... 177 2e-44
sp|Q60900|ELAV3_MOUSE ELAV-like protein 3 (Hu-antigen C) (HuC) 177 2e-44
sp|Q15717|ELAV1_HUMAN ELAV-like protein 1 (Hu-antigen R) (HuR) 176 9e-44
sp|P70372|ELAV1_MOUSE ELAV-like protein 1 (Hu-antigen R) (H... 171 3e-42
sp|P16914|ELAV_DROME Elav protein (Embryonic lethal abnorma... 162 8e-40
>sp|Q12926|ELAV2_HUMAN ELAV-like protein 2 (Hu-antigen B) (HuB) (ELAV-like neuronal
protein 1) (Nervous system-specific RNA binding protein
Hel-N1)
Length = 359
Score = 184 bits (467), Expect = 3e-46
Identities = 101/203 (49%), Positives = 128/203 (63%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TG+SRGV FIRFD+R EA+ AIK LN +P +TEPI VKFAN+PS I + +
Sbjct: 162 TGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQS 221
Query: 187 XXXXXXXXXXXTNPQSRSSLISPLQQLASVARLKYPSSMDFMPSLTGNNSLLAPAFAAST 366
Q++ + L +A + P ++D M SL G N P
Sbjct: 222 PNRRYPGPLAQ---QAQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPG----- 273
Query: 367 GALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYE 546
TGWCIFVYNLAP+ D++ LWQ+FGPFGAV VK+IRD TNKCKGFGFVTM+NY+
Sbjct: 274 -----TGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYD 328
Query: 547 EALLAIQSLNGFTLGNRILQVSF 615
EA +AI+SLNG+ LG+R+LQVSF
Sbjct: 329 EAAMAIRSLNGYRLGDRVLQVSF 351
Score = 48.1 bits (113), Expect = 3e-05
Identities = 29/98 (29%), Positives = 49/98 (50%)
Frame = +1
Query: 322 TGNNSLLAPAFAASTGALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTAT 501
T NN+ +P + +T + V L L LFG G +++ K++RD T
Sbjct: 20 TINNNCSSPVDSGNTEDSKTN---LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKIT 76
Query: 502 NKCKGFGFVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
+ G+GFV + ++A AI +LNG L + ++VS+
Sbjct: 77 GQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSY 114
Score = 37.4 bits (85), Expect = 0.052
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSL 573
++V L L QLF +G + T +I+ D T +G GF+ EA AI+ L
Sbjct: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
Query: 574 NG 579
NG
Sbjct: 187 NG 188
>sp|Q60899|ELAV2_MOUSE ELAV-like protein 2 (Hu-antigen B) (HuB) (ELAV-like neuronal
protein 1) (Nervous system-specific RNA binding protein
Mel-N1)
Length = 360
Score = 183 bits (464), Expect = 6e-46
Identities = 102/203 (50%), Positives = 126/203 (62%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TG+SRGV FIRFD+R EA+ AIK LN +P +TEPI VKFAN+PS ++ N ++
Sbjct: 162 TGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPS--QKTNQAILSQLY 219
Query: 187 XXXXXXXXXXXTNPQSRSSLISPLQQLASVARLKYPSSMDFMPSLTGNNSLLAPAFAAST 366
R L + L V P ++D M SL G N P
Sbjct: 220 QSPNRRYPGPLAQQAQRFRLDNLLNMAYGVKSRFSPMTIDGMTSLAGINIPGHPG----- 274
Query: 367 GALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYE 546
TGWCIFVYNLAP+ D++ LWQ+FGPFGAV VK+IRD TNKCKGFGFVTM+NY+
Sbjct: 275 -----TGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYD 329
Query: 547 EALLAIQSLNGFTLGNRILQVSF 615
EA +AI SLNG+ LG+R+LQVSF
Sbjct: 330 EAAMAIASLNGYRLGDRVLQVSF 352
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/98 (29%), Positives = 49/98 (50%)
Frame = +1
Query: 322 TGNNSLLAPAFAASTGALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTAT 501
T NN+ +P + +T + V L L LFG G +++ K++RD T
Sbjct: 20 TVNNNCSSPVDSGNTEDSKTN---LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKIT 76
Query: 502 NKCKGFGFVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
+ G+GFV + ++A AI +LNG L + ++VS+
Sbjct: 77 GQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSY 114
Score = 37.4 bits (85), Expect = 0.052
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSL 573
++V L L QLF +G + T +I+ D T +G GF+ EA AI+ L
Sbjct: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
Query: 574 NG 579
NG
Sbjct: 187 NG 188
>sp|P26378|ELAV4_HUMAN ELAV-like protein 4 (Paraneoplastic encephalomyelitis antigen HuD)
(Hu-antigen D)
Length = 380
Score = 181 bits (458), Expect = 3e-45
Identities = 104/210 (49%), Positives = 131/210 (62%), Gaps = 7/210 (3%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TG+SRGV FIRFD+R EA+ AIK LN +P +TEPI VKFAN+PS + + +
Sbjct: 169 TGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQS 228
Query: 187 XXXXXXXXXXXTNPQSRSSLISPLQQLASVARLKY----PSSMD--FMP-SLTGNNSLLA 345
+ R L + L V RL PS+ F P ++ G SL+
Sbjct: 229 PNRRYPGPLH--HQAQRFRLDNLLNMAYGVKRLMSGPVPPSACSPRFSPITIDGMTSLVG 286
Query: 346 PAFAASTGALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGF 525
TG TGWCIFVYNL+P++D++ LWQLFGPFGAV VK+IRD TNKCKGFGF
Sbjct: 287 MNIPGHTG----TGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGF 342
Query: 526 VTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
VTM+NY+EA +AI SLNG+ LG+R+LQVSF
Sbjct: 343 VTMTNYDEAAMAIASLNGYRLGDRVLQVSF 372
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Frame = +1
Query: 364 TGALTATGWCIFVYNLAPET-DDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSN 540
TGA T + N P+ LFG G +++ K++RD T + G+GFV +
Sbjct: 37 TGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYID 96
Query: 541 YEEALLAIQSLNGFTLGNRILQVSF 615
++A AI +LNG L + ++VS+
Sbjct: 97 PKDAEKAINTLNGLRLQTKTIKVSY 121
Score = 37.7 bits (86), Expect = 0.040
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSL 573
++V L L QLF +G + T +I+ D T +G GF+ EA AI+ L
Sbjct: 134 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 193
Query: 574 NG 579
NG
Sbjct: 194 NG 195
>sp|O09032|ELAV4_RAT ELAV-like protein 4 (Paraneoplastic encephalomyelitis antigen HuD)
(Hu-antigen D)
Length = 373
Score = 180 bits (457), Expect = 4e-45
Identities = 104/210 (49%), Positives = 131/210 (62%), Gaps = 7/210 (3%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TG+SRGV FIRFD+R EA+ AIK LN +P +TEPI VKFAN+PS + + +
Sbjct: 162 TGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQS 221
Query: 187 XXXXXXXXXXXTNPQSRSSLISPLQQLASVARLKY----PSSMD--FMP-SLTGNNSLLA 345
+ R L + L V RL PS+ F P ++ G SL+
Sbjct: 222 PNRRYPGPLH--HQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVG 279
Query: 346 PAFAASTGALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGF 525
TG TGWCIFVYNL+P++D++ LWQLFGPFGAV VK+IRD TNKCKGFGF
Sbjct: 280 MNIPGHTG----TGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGF 335
Query: 526 VTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
VTM+NY+EA +AI SLNG+ LG+R+LQVSF
Sbjct: 336 VTMTNYDEAAMAIASLNGYRLGDRVLQVSF 365
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Frame = +1
Query: 364 TGALTATGWCIFVYNLAPET-DDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSN 540
TGA T + N P+ LFG G +++ K++RD T + G+GFV +
Sbjct: 30 TGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYID 89
Query: 541 YEEALLAIQSLNGFTLGNRILQVSF 615
++A AI +LNG L + ++VS+
Sbjct: 90 PKDAEKAINTLNGLRLQTKTIKVSY 114
Score = 37.7 bits (86), Expect = 0.040
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSL 573
++V L L QLF +G + T +I+ D T +G GF+ EA AI+ L
Sbjct: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 574 NG 579
NG
Sbjct: 187 NG 188
>sp|Q61701|ELAV4_MOUSE ELAV-like protein 4 (Paraneoplastic encephalomyelitis antigen HuD)
(Hu-antigen D)
Length = 385
Score = 180 bits (457), Expect = 4e-45
Identities = 104/210 (49%), Positives = 131/210 (62%), Gaps = 7/210 (3%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TG+SRGV FIRFD+R EA+ AIK LN +P +TEPI VKFAN+PS + + +
Sbjct: 174 TGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQS 233
Query: 187 XXXXXXXXXXXTNPQSRSSLISPLQQLASVARLKY----PSSMD--FMP-SLTGNNSLLA 345
+ R L + L V RL PS+ F P ++ G SL+
Sbjct: 234 PNRRYPGPLH--HQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVG 291
Query: 346 PAFAASTGALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGF 525
TG TGWCIFVYNL+P++D++ LWQLFGPFGAV VK+IRD TNKCKGFGF
Sbjct: 292 MNIPGHTG----TGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGF 347
Query: 526 VTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
VTM+NY+EA +AI SLNG+ LG+R+LQVSF
Sbjct: 348 VTMTNYDEAAMAIASLNGYRLGDRVLQVSF 377
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Frame = +1
Query: 364 TGALTATGWCIFVYNLAPET-DDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSN 540
TGA T + N P+ LFG G +++ K++RD T + G+GFV +
Sbjct: 42 TGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYID 101
Query: 541 YEEALLAIQSLNGFTLGNRILQVSF 615
++A AI +LNG L + ++VS+
Sbjct: 102 PKDAEKAINTLNGLRLQTKTIKVSY 126
Score = 37.7 bits (86), Expect = 0.040
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSL 573
++V L L QLF +G + T +I+ D T +G GF+ EA AI+ L
Sbjct: 139 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 198
Query: 574 NG 579
NG
Sbjct: 199 NG 200
>sp|Q14576|ELAV3_HUMAN ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic cerebellar
degeneration-associated antigen) (Paraneoplastic limbic
encephalitis antigen 21)
Length = 367
Score = 177 bits (450), Expect = 2e-44
Identities = 99/211 (46%), Positives = 124/211 (58%), Gaps = 8/211 (3%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TG+SRGV FIRFD+R EA+ AIK LN +P + EPI VKFAN+PS + + +
Sbjct: 162 TGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQS 221
Query: 187 XXXXXXXXXXXTNPQSRSSLI--------SPLQQLASVARLKYPSSMDFMPSLTGNNSLL 342
+ R + SPL +A + P ++D M L G
Sbjct: 222 SARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFS----PIAIDGMSGLAG----- 272
Query: 343 APAFAASTGALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFG 522
+G GWCIFVYNL+PE D++ LWQLFGPFGAV VK+IRD TNKCKGFG
Sbjct: 273 ----VGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFG 328
Query: 523 FVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
FVTM+NY+EA +AI SLNG+ LG R+LQVSF
Sbjct: 329 FVTMTNYDEAAMAIASLNGYRLGERVLQVSF 359
Score = 48.1 bits (113), Expect = 3e-05
Identities = 22/57 (38%), Positives = 36/57 (63%)
Frame = +1
Query: 445 LFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
LFG G +++ K++RD T + G+GFV S+ +A AI +LNG L + ++VS+
Sbjct: 58 LFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSY 114
Score = 37.4 bits (85), Expect = 0.052
Identities = 20/62 (32%), Positives = 30/62 (48%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSL 573
++V L + QLF +G + T +I+ D T +G GF+ EA AI+ L
Sbjct: 127 LYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 574 NG 579
NG
Sbjct: 187 NG 188
>sp|Q60900|ELAV3_MOUSE ELAV-like protein 3 (Hu-antigen C) (HuC)
Length = 367
Score = 177 bits (450), Expect = 2e-44
Identities = 99/211 (46%), Positives = 124/211 (58%), Gaps = 8/211 (3%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TG+SRGV FIRFD+R EA+ AIK LN +P + EPI VKFAN+PS + + +
Sbjct: 162 TGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQS 221
Query: 187 XXXXXXXXXXXTNPQSRSSLI--------SPLQQLASVARLKYPSSMDFMPSLTGNNSLL 342
+ R + SPL +A + P ++D M L G
Sbjct: 222 SARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFS----PIAIDGMSGLAG----- 272
Query: 343 APAFAASTGALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFG 522
+G GWCIFVYNL+PE D++ LWQLFGPFGAV VK+IRD TNKCKGFG
Sbjct: 273 ----VGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFG 328
Query: 523 FVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
FVTM+NY+EA +AI SLNG+ LG R+LQVSF
Sbjct: 329 FVTMTNYDEAAMAIASLNGYRLGERVLQVSF 359
Score = 48.1 bits (113), Expect = 3e-05
Identities = 22/57 (38%), Positives = 36/57 (63%)
Frame = +1
Query: 445 LFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
LFG G +++ K++RD T + G+GFV S+ +A AI +LNG L + ++VS+
Sbjct: 58 LFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSY 114
Score = 39.3 bits (90), Expect = 0.014
Identities = 21/62 (33%), Positives = 31/62 (50%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSL 573
++V L + QLF +G + T +I+ D AT +G GF+ EA AI+ L
Sbjct: 127 LYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 574 NG 579
NG
Sbjct: 187 NG 188
>sp|Q15717|ELAV1_HUMAN ELAV-like protein 1 (Hu-antigen R) (HuR)
Length = 326
Score = 176 bits (445), Expect = 9e-44
Identities = 102/203 (50%), Positives = 127/203 (62%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TGLSRGVAFIRFD+RSEA+ AI N ++P S+EPI VKFA +P+ N ++A+L
Sbjct: 143 TGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPN----QNKNVALLSQ 198
Query: 187 XXXXXXXXXXXTNPQSRSSLISPLQQLASVARLKYPSSMDFMPSLTGNNSLLAPAFAAST 366
+P R P+ A R P +D M L+G N P A+S
Sbjct: 199 LYH---------SPARRFG--GPVHHQAQRFRFS-PMGVDHMSGLSGVN---VPGNASS- 242
Query: 367 GALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYE 546
GWCIF+YNL + D+ LWQ+FGPFGAV VK+IRD TNKCKGFGFVTM+NYE
Sbjct: 243 ------GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYE 296
Query: 547 EALLAIQSLNGFTLGNRILQVSF 615
EA +AI SLNG+ LG++ILQVSF
Sbjct: 297 EAAMAIASLNGYRLGDKILQVSF 319
Score = 44.3 bits (103), Expect = 4e-04
Identities = 22/60 (36%), Positives = 34/60 (56%)
Frame = +1
Query: 436 LWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
L LF G V++ K+IRD G+GFV ++A AI +LNG L ++ ++VS+
Sbjct: 36 LRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSY 95
>sp|P70372|ELAV1_MOUSE ELAV-like protein 1 (Hu-antigen R) (HuR) (Elav-like generic
protein) (MelG)
Length = 326
Score = 171 bits (432), Expect = 3e-42
Identities = 99/203 (48%), Positives = 126/203 (62%)
Frame = +1
Query: 7 TGLSRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSPSTSRQDNISLAILKX 186
TGLSRGVAFIRFD+RSEA+ AI ++P S+EPI VKFA +P+ N ++A+L
Sbjct: 143 TGLSRGVAFIRFDKRSEAEEAITSFIGHKPPGSSEPITVKFAANPN----QNKNMALLSQ 198
Query: 187 XXXXXXXXXXXTNPQSRSSLISPLQQLASVARLKYPSSMDFMPSLTGNNSLLAPAFAAST 366
+P R P+ A R P +D M ++G N P A+S
Sbjct: 199 LYH---------SPARRFG--GPVHHQAQRFRFS-PMGVDHMSGISGVN---VPGNASS- 242
Query: 367 GALTATGWCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYE 546
GWCIF+YNL + D+ LWQ+FGPFGAV VK+IRD TNKCKGFGFVTM+NYE
Sbjct: 243 ------GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYE 296
Query: 547 EALLAIQSLNGFTLGNRILQVSF 615
E+ +AI SLNG+ LG++ILQVSF
Sbjct: 297 ESAMAIASLNGYRLGDKILQVSF 319
Score = 44.3 bits (103), Expect = 4e-04
Identities = 22/60 (36%), Positives = 34/60 (56%)
Frame = +1
Query: 436 LWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEEALLAIQSLNGFTLGNRILQVSF 615
L LF G V++ K+IRD G+GFV ++A AI +LNG L ++ ++VS+
Sbjct: 36 LRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNGLRLQSKTIKVSY 95
>sp|P16914|ELAV_DROME Elav protein (Embryonic lethal abnormal visual protein)
Length = 483
Score = 162 bits (411), Expect = 8e-40
Identities = 93/202 (46%), Positives = 127/202 (62%), Gaps = 2/202 (0%)
Frame = +1
Query: 16 SRGVAFIRFDQRSEAQLAIKKLNSYQPENSTEPIIVKFANSP-STSRQDNISLAILKXXX 192
++GV FIRFD+R EA AI LN P + T+PI+VKF+N+P STS+ L
Sbjct: 289 TKGVGFIRFDKREEATRAIIALNGTTPSSCTDPIVVKFSNTPGSTSKIIQPQLPAF---- 344
Query: 193 XXXXXXXXXTNPQSRSSLISPLQQLASVARLKYPSSMDFMPSLTGNNSLLAPAFAASTGA 372
NPQ + + + ++ M + N L A A AA+T A
Sbjct: 345 ---------LNPQLVRRIGGAMHTPVNKGLARFSPMAGDMLDVMLPNGLGAAAAAATTLA 395
Query: 373 LTATG-WCIFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATNKCKGFGFVTMSNYEE 549
G + IF+YNLAPET++A LWQLFGPFGAVQ+VKI++D TN+CKG+GFV+M+NY+E
Sbjct: 396 SGPGGAYPIFIYNLAPETEEAALWQLFGPFGAVQSVKIVKDPTTNQCKGYGFVSMTNYDE 455
Query: 550 ALLAIQSLNGFTLGNRILQVSF 615
A +AI++LNG+T+GNR+LQVSF
Sbjct: 456 AAMAIRALNGYTMGNRVLQVSF 477
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/142 (25%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Frame = +1
Query: 229 QSRSSLISPLQQLASVARLKYPSSMDFMPSLTGNNSLLAPAFAASTGALTATGWCIFVYN 408
Q + + + Q A+V + P P+ GN + + S G+ T T + V
Sbjct: 99 QQQQQQAAAVVQQAAVQQAVVPQPQQAQPNTNGNAG--SGSQNGSNGS-TETRTNLIVNY 155
Query: 409 LAPETDDATLWQLFGPFGAVQTVKIIRDTAT-------------NKCKGFGFVTMSNYEE 549
L + + LF G +++VK+IRD + + G+GFV ++
Sbjct: 156 LPQTMTEDEIRSLFSSVGEIESVKLIRDKSQVYIDPLNPQAPSKGQSLGYGFVNYVRPQD 215
Query: 550 ALLAIQSLNGFTLGNRILQVSF 615
A A+ LNG L N+ ++VSF
Sbjct: 216 AEQAVNVLNGLRLQNKTIKVSF 237
Score = 41.2 bits (95), Expect = 0.004
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +1
Query: 394 IFVYNLAPETDDATLWQLFGPFGAVQTVKIIRDTATN-KCKGFGFVTMSNYEEALLAIQS 570
++V L L +F PFGA+ T +I+++ + + KG GF+ EEA AI +
Sbjct: 250 LYVSGLPKTMTQQELEAIFAPFGAIITSRILQNAGNDTQTKGVGFIRFDKREEATRAIIA 309
Query: 571 LNGFT 585
LNG T
Sbjct: 310 LNGTT 314
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,266,340
Number of Sequences: 369166
Number of extensions: 1587988
Number of successful extensions: 4409
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3910
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4352
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)