Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_E06
(854 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9U4L6|TOM40_DROME Probable mitochondrial import recepto... 164 4e-40
sp|O96008|TOM40_HUMAN Probable mitochondrial import recepto... 142 1e-33
sp|Q9QYA2|TOM40_MOUSE Probable mitochondrial import recepto... 140 6e-33
sp|Q18090|TOM40_CAEEL Probable mitochondrial import recepto... 135 1e-31
sp|O13656|TOM40_SCHPO Probable mitochondrial import recepto... 66 1e-10
sp|P23644|TOM40_YEAST Mitochondrial import receptor subunit... 44 4e-04
sp|Q9LHE5|TOM40_ARATH Probable mitochondrial import recepto... 34 0.45
sp|Q59088|G6PI_ACIAD Glucose-6-phosphate isomerase (GPI) (P... 32 2.2
sp|O74161|CHS5_CANAL Chitin biosynthesis protein CHS5 31 3.8
sp|O70342|NPY5R_MOUSE Neuropeptide Y receptor type 5 (NPY5-... 31 5.0
>sp|Q9U4L6|TOM40_DROME Probable mitochondrial import receptor subunit TOM40 homolog
(Translocase of outer membrane 40 kDa subunit homolog)
(Male sterile protein 15)
Length = 344
Score = 164 bits (414), Expect = 4e-40
Identities = 78/224 (34%), Positives = 130/224 (58%), Gaps = 2/224 (0%)
Frame = +1
Query: 184 TMESLHNITHEIFPVPFEGVKLVVNQGFNQHFQLNHSFAFGSEKQSGYKFGATYVGNTKL 363
T+E LH +I + FEG K+++N+G + HFQ++H+ + SGY+FGATYVG +
Sbjct: 62 TVEELHKKCKDIQAITFEGAKIMLNKGLSNHFQVSHTINMSNVVPSGYRFGATYVGTKEF 121
Query: 364 SETEIYPIMLGELSPNGNLNAQIIHQFNQKIKCKYVSQMKVGKIDGQQFSIEHRNKNINL 543
S TE +P++LG++ P GNLNA +IHQF+ +++CK+ SQ++ K+ Q + ++R + L
Sbjct: 122 SPTEAFPVLLGDIDPAGNLNANVIHQFSARLRCKFASQIQESKVVASQLTTDYRGSDYTL 181
Query: 544 GFSIVNPSIQNKEISCIFDVMRRITDKLSLGSMFVFQRSNQAQFTNFGVWNVGGQYVGNK 723
++ NPSI + ++ +T L+LGS +Q + +V G+Y
Sbjct: 182 SLTVANPSIFTNSGVVVGQYLQSVTPALALGSELAYQFGPNVPGRQIAIMSVVGRYTAGS 241
Query: 724 --WTAAVGVRPFQSSLHSTFHMKLNEAFQIGTEIETSLGHRQCV 849
W+ +G QS LH ++ K ++ QIG E+ETSL ++ V
Sbjct: 242 SVWSGTLG----QSGLHVCYYQKASDQLQIGAEVETSLRMQESV 281
>sp|O96008|TOM40_HUMAN Probable mitochondrial import receptor subunit TOM40 homolog
(Translocase of outer membrane 40 kDa subunit homolog)
(Haymaker protein) (p38.5)
Length = 361
Score = 142 bits (358), Expect = 1e-33
Identities = 74/215 (34%), Positives = 118/215 (54%)
Frame = +1
Query: 184 TMESLHNITHEIFPVPFEGVKLVVNQGFNQHFQLNHSFAFGSEKQSGYKFGATYVGNTKL 363
T E H E+FP+ EGVKL VN+G + HFQ+NH+ A + +S Y FG TYVG +L
Sbjct: 82 TFEECHRKCKELFPIQMEGVKLTVNKGLSNHFQVNHTVALSTIGESNYHFGVTYVGTKQL 141
Query: 364 SETEIYPIMLGELSPNGNLNAQIIHQFNQKIKCKYVSQMKVGKIDGQQFSIEHRNKNINL 543
S TE +P+++G++ +G+LNAQ+IHQ ++ K Q + K Q E+R +
Sbjct: 142 SPTEAFPVLVGDMDNSGSLNAQVIHQLGPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTA 201
Query: 544 GFSIVNPSIQNKEISCIFDVMRRITDKLSLGSMFVFQRSNQAQFTNFGVWNVGGQYVGNK 723
++ NP + + ++ IT L+LG V+ R + T V ++ G+Y N
Sbjct: 202 AVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGT---VMSLAGKYTLNN 258
Query: 724 WTAAVGVRPFQSSLHSTFHMKLNEAFQIGTEIETS 828
W A V + Q+ +H+T++ K ++ Q+G E E S
Sbjct: 259 WLATVTLG--QAGMHATYYHKASDQLQVGVEFEAS 291
>sp|Q9QYA2|TOM40_MOUSE Probable mitochondrial import receptor subunit TOM40 homolog
(Translocase of outer membrane 40 kDa subunit homolog)
Length = 359
Score = 140 bits (352), Expect = 6e-33
Identities = 74/215 (34%), Positives = 118/215 (54%)
Frame = +1
Query: 184 TMESLHNITHEIFPVPFEGVKLVVNQGFNQHFQLNHSFAFGSEKQSGYKFGATYVGNTKL 363
T E H E+FPV EGVKL VN+G + FQ+ H+ A G+ +S Y FG TYVG +L
Sbjct: 80 TFEECHRKCKELFPVQMEGVKLTVNKGLSNRFQVTHTVALGTIGESNYHFGVTYVGTKQL 139
Query: 364 SETEIYPIMLGELSPNGNLNAQIIHQFNQKIKCKYVSQMKVGKIDGQQFSIEHRNKNINL 543
S TE +P+++G++ +G+LNAQ+IHQ + ++ K Q + K Q E+R +
Sbjct: 140 SPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTA 199
Query: 544 GFSIVNPSIQNKEISCIFDVMRRITDKLSLGSMFVFQRSNQAQFTNFGVWNVGGQYVGNK 723
++ NP + + ++ IT L+LG V+ R + T V ++ G+Y N
Sbjct: 200 AVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGT---VMSLAGKYTLNN 256
Query: 724 WTAAVGVRPFQSSLHSTFHMKLNEAFQIGTEIETS 828
W A V + Q+ +H+T++ K ++ Q+G E E S
Sbjct: 257 WLATVTLG--QAGMHATYYHKASDQLQVGVEFEAS 289
>sp|Q18090|TOM40_CAEEL Probable mitochondrial import receptor subunit TOM40 homolog
(Translocase of outer membrane 40 kDa subunit homolog)
Length = 301
Score = 135 bits (341), Expect = 1e-31
Identities = 73/211 (34%), Positives = 114/211 (54%)
Frame = +1
Query: 190 ESLHNITHEIFPVPFEGVKLVVNQGFNQHFQLNHSFAFGSEKQSGYKFGATYVGNTKLSE 369
E LH ++FP FEG KL+VN+G + HFQ++H+ + S +GY+FGATYVG ++
Sbjct: 22 EELHRKARDVFPTCFEGAKLMVNKGLSSHFQVSHTLSL-SAMNTGYRFGATYVGTNQVGP 80
Query: 370 TEIYPIMLGELSPNGNLNAQIIHQFNQKIKCKYVSQMKVGKIDGQQFSIEHRNKNINLGF 549
E YPI+LG+ NGN A I+HQ + K Q++ GK+ G Q +IE + + LG
Sbjct: 81 AEAYPILLGDTDVNGNTTATILHQLG-IYRTKLQGQIQQGKLAGAQATIERKGRLSTLGL 139
Query: 550 SIVNPSIQNKEISCIFDVMRRITDKLSLGSMFVFQRSNQAQFTNFGVWNVGGQYVGNKWT 729
++ N + N+ + +RR+T +L +G+ V+Q V + +Y N +
Sbjct: 140 TLANIDLVNEAGILVGQFLRRLTPRLDVGTEMVYQYGKNIPGGQISVLSYAARYTANHFI 199
Query: 730 AAVGVRPFQSSLHSTFHMKLNEAFQIGTEIE 822
AA + S +H T++ K NE G E E
Sbjct: 200 AAATLG--ASGVHLTYYHKQNENLAFGVEFE 228
>sp|O13656|TOM40_SCHPO Probable mitochondrial import receptor subunit tom40 (Translocase
of outer membrane 40 kDa subunit)
Length = 344
Score = 65.9 bits (159), Expect = 1e-10
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 5/204 (2%)
Frame = +1
Query: 232 FEGVKLVVNQGF--NQHFQLNHSFAFGSEKQSGYKFGATYVGNTKLSETEIYPIML-GEL 402
F GV+ V +GF + F ++H+FA GS+ Y F + G P+ L G +
Sbjct: 51 FTGVRADVTKGFCTSPWFTVSHAFALGSQVLPPYSFSTMFGGE---------PLFLRGSV 101
Query: 403 SPNGNLNAQIIHQFNQKIKCKYVSQMKVGKIDGQ-QFSIEHRNKNINLGFSIVNPSIQNK 579
+G + A + +N + K Q+ G + Q +H+ K+ + F +NP + K
Sbjct: 102 DNDGAVQAMLNCTWNSNVLSKVQMQLSNGAVPNMCQIEHDHKGKDFSFSFKAMNPWYEEK 161
Query: 580 EISC-IFDVMRRITDKLSLGSMFVFQRSNQAQFTNFGVWNVGGQYVGNKWTAAVGVRPFQ 756
I +++ +T KLSLG ++Q+ + + + +Y W A + Q
Sbjct: 162 LTGIYIISLLQSVTPKLSLGVEALWQKPSSSIGPEEATLSYMTRYNAADWIATAHLNGSQ 221
Query: 757 SSLHSTFHMKLNEAFQIGTEIETS 828
+ +TF KL+ + G E + S
Sbjct: 222 GDVTATFWRKLSPKVEAGVECQLS 245
>sp|P23644|TOM40_YEAST Mitochondrial import receptor subunit TOM40 (Mitochondrial
import-site-protein ISP42) (Translocase of outer
membrane 40 kDa subunit)
Length = 387
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/177 (23%), Positives = 88/177 (49%), Gaps = 8/177 (4%)
Frame = +1
Query: 184 TMESLHN-ITHEIFPVP--FEGVKLVVNQGF--NQHFQLNHSFAFGSEKQSGYKFGATYV 348
T+E+L+ ++ ++F F G++ +N+ F N FQ +H+F+ GS+ Y F A +
Sbjct: 62 TVENLNKEVSRDVFLSQYFFTGLRADLNKAFSMNPAFQTSHTFSIGSQALPKYAFSALFA 121
Query: 349 GNTKLSETEIYPIMLGELSPNGNLNAQIIHQFNQKIKCKYVSQMKVGKIDGQQFSIEHRN 528
+ ++ I +LS +G LN + +++K K Q+ G+ Q +++
Sbjct: 122 NDNLFAQGNID----NDLSVSGRLN----YGWDKKNISKVNLQISDGQPTMCQLEQDYQA 173
Query: 529 KNINLGFSIVNPSIQNK-EIS--CIFDVMRRITDKLSLGSMFVFQRSNQAQFTNFGV 690
+ ++ +NPS K E + + ++ +T +L+LG ++ R++ + + GV
Sbjct: 174 SDFSVNVKTLNPSFSEKGEFTGVAVASFLQSVTPQLALGLETLYSRTDGSAPGDAGV 230
>sp|Q9LHE5|TOM40_ARATH Probable mitochondrial import receptor subunit TOM40 homolog
(Translocase of outer membrane 40 kDa subunit homolog)
Length = 309
Score = 34.3 bits (77), Expect = 0.45
Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 17/123 (13%)
Frame = +1
Query: 148 KMAESSDSKGLPT---MESLHN-ITHEIFPVPFEGVKLVVNQGFNQHFQLNHSFAFGSEK 315
K+ E D LP+ E LH + FEG++ + NQ F L+HS G +
Sbjct: 18 KVDEKVDYSNLPSPVPYEELHREALMSLKSDNFEGLRFDFTRALNQKFSLSHSVMMGPTE 77
Query: 316 -------------QSGYKFGATYVGNTKLSETEIYPIMLGELSPNGNLNAQIIHQFNQKI 456
+ Y+FGA Y + KL +++G + +G LNA++ K+
Sbjct: 78 VPAQSPETTIKIPTAHYEFGANYY-DPKL-------LLIGRVMTDGRLNARLKADLTDKL 129
Query: 457 KCK 465
K
Sbjct: 130 VVK 132
>sp|Q59088|G6PI_ACIAD Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
(PGI) (Phosphohexose isomerase) (PHI)
Length = 557
Score = 32.0 bits (71), Expect = 2.2
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Frame = +1
Query: 352 NTKLSETEIYPIMLGELSPNG-NLNAQIIHQFNQKIKCKYVSQM 480
N + E PI+ GE+ PN + Q++HQ QK+ C +++ M
Sbjct: 370 NGQKVENTTCPIVWGEVGPNAQHAFYQLLHQGTQKVSCDFIAPM 413
>sp|O74161|CHS5_CANAL Chitin biosynthesis protein CHS5
Length = 562
Score = 31.2 bits (69), Expect = 3.8
Identities = 17/58 (29%), Positives = 29/58 (50%)
Frame = +1
Query: 358 KLSETEIYPIMLGELSPNGNLNAQIIHQFNQKIKCKYVSQMKVGKIDGQQFSIEHRNK 531
K+++ + LG+L+PN N + I + + + KY Q +V K+D F NK
Sbjct: 165 KMTDLSGITVCLGDLTPNDQFNKEDIEEALKNMGAKYPVQQQV-KVDTTHFLCTRENK 221
>sp|O70342|NPY5R_MOUSE Neuropeptide Y receptor type 5 (NPY5-R) (NPY-Y5 receptor) (Y5
receptor)
Length = 466
Score = 30.8 bits (68), Expect = 5.0
Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 6/93 (6%)
Frame = -3
Query: 564 WIDY------TKT*INVLIPVFYRKLLPIDFSNFHLTNIFTFNFLIELMNNLSIQIPIWA 403
W DY T N PV+ +D + L ++TF L+ M NL I + +
Sbjct: 30 WEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMK 89
Query: 402 QLPQHNRINFSL**FCITYICSSEFITALFFAP 304
+ Q +N F I + S+ + LF +P
Sbjct: 90 KRNQKTTVN-----FLIGNLAFSDILVVLFCSP 117
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,561,454
Number of Sequences: 369166
Number of extensions: 2094073
Number of successful extensions: 4659
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4461
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4650
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)