Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_D22
(883 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8VHR5|P66B_MOUSE Transcriptional repressor p66 beta (p6... 97 6e-20
sp|Q8WXI9|P66B_HUMAN Transcriptional repressor p66 beta (p6... 95 3e-19
sp|Q86YP4|P66A_HUMAN Transcriptional repressor p66 alpha (H... 94 5e-19
sp|Q8CHY6|P66A_MOUSE Transcriptional repressor p66 alpha (G... 94 5e-19
sp|P15976|GATA1_HUMAN Erythroid transcription factor (GATA-... 37 0.095
sp|P43429|GATA1_RAT Erythroid transcription factor (GATA-bi... 36 0.16
sp|P17679|GATA1_MOUSE Erythroid transcription factor (GATA-... 36 0.16
sp|P17678|GATA1_CHICK Erythroid transcription factor (GATA-... 35 0.21
sp|P23768|GAT1B_XENLA GATA-binding factor 1-B (Transcriptio... 35 0.36
sp|P23767|GAT1A_XENLA GATA-binding factor 1-A (Transcriptio... 35 0.36
>sp|Q8VHR5|P66B_MOUSE Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger
domain-containing protein 2B)
Length = 594
Score = 97.1 bits (240), Expect = 6e-20
Identities = 75/242 (30%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
Frame = +3
Query: 180 PGNRTSAHCASNNTTASYTNES--------NKSSSNGPRMTREMAMQALDQQYLARKALL 335
P + +S C ++A Y N + N+ SS P + AM A K L
Sbjct: 301 PQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPS---AMSDAANSQAAAKLAL 357
Query: 336 RKQADKALSEVPLARPLQGPMAQSDLNLIPSTATNEFVALVGLEEVVKNLQEYRNLALGH 515
RKQ +K L E+P +P P+ L+ +PS A +EF+ +VGLEEVV+++ + + G
Sbjct: 358 RKQLEKTLLEIPPPKP-PAPL----LHFLPSAANSEFIYMVGLEEVVQSVIDSQ----GK 408
Query: 516 NTNEVRMVFTPFNCVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQNDYQDKIRLV 695
N + V PF C QC TDFTP WK+E+ G K++CE C N ++AL+ ++ ++++
Sbjct: 409 NCASLLRV-EPFVCAQCRTDFTPHWKQEKNG--KILCEQCMTSNQKKALKAEHTNRLKNA 465
Query: 696 LKKYQDQERDLDRDYKDMLDSPKKFELFRKEQEKKLMAMNASNTRPSAVASQQGSRTSTG 875
K QE+++++ R +Q+ L S T AV+S T
Sbjct: 466 FVKALQQEQEIEQ---------------RLQQQAAL-----SPTTAPAVSSVSKQETIMR 505
Query: 876 HH 881
HH
Sbjct: 506 HH 507
>sp|Q8WXI9|P66B_HUMAN Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger
domain-containing protein 2B)
Length = 593
Score = 94.7 bits (234), Expect = 3e-19
Identities = 74/242 (30%), Positives = 118/242 (48%), Gaps = 8/242 (3%)
Frame = +3
Query: 180 PGNRTSAHCASNNTTASYTNES--------NKSSSNGPRMTREMAMQALDQQYLARKALL 335
P + +S C ++A Y N + N+ SS P + AM A K L
Sbjct: 300 PQSSSSVPCQRTTSSAIYMNLASHIQPGTVNRVSSPLPSPS---AMTDAANSQAAAKLAL 356
Query: 336 RKQADKALSEVPLARPLQGPMAQSDLNLIPSTATNEFVALVGLEEVVKNLQEYRNLALGH 515
RKQ +K L E+P +P P+ L+ +PS A +EF+ +VGLEEVV+++ + + G
Sbjct: 357 RKQLEKTLLEIPPPKP-PAPL----LHFLPSAANSEFIYMVGLEEVVQSVIDSQ----GK 407
Query: 516 NTNEVRMVFTPFNCVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQNDYQDKIRLV 695
+ + V PF C QC TDFTP WK+E+ G K++CE C N ++AL+ ++ ++++
Sbjct: 408 SCASLLRV-EPFVCAQCRTDFTPHWKQEKNG--KILCEQCMTSNQKKALKAEHTNRLKNA 464
Query: 696 LKKYQDQERDLDRDYKDMLDSPKKFELFRKEQEKKLMAMNASNTRPSAVASQQGSRTSTG 875
K QE+++++ R +Q+ L S T AV+S T
Sbjct: 465 FVKALQQEQEIEQ---------------RLQQQAAL-----SPTTAPAVSSVSKQETIMR 504
Query: 876 HH 881
HH
Sbjct: 505 HH 506
>sp|Q86YP4|P66A_HUMAN Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger
domain-containing protein 2A)
Length = 633
Score = 94.0 bits (232), Expect = 5e-19
Identities = 50/139 (35%), Positives = 81/139 (58%)
Frame = +3
Query: 318 ARKALLRKQADKALSEVPLARPLQGPMAQSDLNLIPSTATNEFVALVGLEEVVKNLQEYR 497
A K LRKQ +K L E+P +P ++N +PS A NEF+ LVGLEEVV+NL E +
Sbjct: 347 AAKLALRKQLEKTLLEIPPPKP-----PAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQ 401
Query: 498 NLALGHNTNEVRMVFTPFNCVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQNDYQ 677
G + + P+ C QC TDFT W+ E+ G+ ++CE+C N ++AL+ ++
Sbjct: 402 ----GRMSAATVLSREPYMCAQCKTDFTCRWREEKSGA--IMCENCMTTNQKKALKVEHT 455
Query: 678 DKIRLVLKKYQDQERDLDR 734
+++ K QE+++++
Sbjct: 456 SRLKAAFVKALQQEQEIEQ 474
>sp|Q8CHY6|P66A_MOUSE Transcriptional repressor p66 alpha (GATA zinc finger
domain-containing protein 2A)
Length = 629
Score = 94.0 bits (232), Expect = 5e-19
Identities = 59/176 (33%), Positives = 95/176 (53%)
Frame = +3
Query: 207 ASNNTTASYTNESNKSSSNGPRMTREMAMQALDQQYLARKALLRKQADKALSEVPLARPL 386
AS TA + ++N + ++ + A Q A K LRKQ +K L E+P +P
Sbjct: 307 ASMKGTAVASAQANSTPTSVASVVASAESPASRQA--AAKLALRKQLEKTLLEIPPPKP- 363
Query: 387 QGPMAQSDLNLIPSTATNEFVALVGLEEVVKNLQEYRNLALGHNTNEVRMVFTPFNCVQC 566
++N +PS A NEF+ LVGLEEVV+NL E + + + P+ CVQC
Sbjct: 364 ----PAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQAGRISATAAAAVLSREPYMCVQC 419
Query: 567 GTDFTPLWKRERPGSSKVVCESCCGENHRRALQNDYQDKIRLVLKKYQDQERDLDR 734
TDFT W RE+ G+ V+CE+C N ++AL+ ++ +++ K QE+++++
Sbjct: 420 KTDFTCRW-REKGGA--VMCENCMTSNQKKALKVEHTSRLKAAFVKALQQEQEMEQ 472
>sp|P15976|GATA1_HUMAN Erythroid transcription factor (GATA-binding factor 1) (GATA-1)
(Eryf1) (GF-1) (NF-E1 DNA-binding protein)
Length = 413
Score = 36.6 bits (83), Expect = 0.095
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = +3
Query: 555 CVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQND--YQDKIRLVLKK 704
CV CG TPLW+R+R G +C + CG H+ QN + K RL++ K
Sbjct: 204 CVNCGATATPLWRRDRTG--HYLC-NACGLYHKMNGQNRPLIRPKKRLIVSK 252
>sp|P43429|GATA1_RAT Erythroid transcription factor (GATA-binding factor 1) (GATA-1)
(Eryf1) (GF-1) (NF-E1 DNA-binding protein)
Length = 413
Score = 35.8 bits (81), Expect = 0.16
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = +3
Query: 555 CVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQND--YQDKIRLVLKK 704
CV CG TPLW+R+R G +C + CG H+ QN + K R+++ K
Sbjct: 204 CVNCGATATPLWRRDRTG--HYLC-NACGLYHKMNGQNRPLIRPKKRMIVSK 252
>sp|P17679|GATA1_MOUSE Erythroid transcription factor (GATA-binding factor 1) (GATA-1)
(Eryf1) (GF-1) (NF-E1 DNA-binding protein)
Length = 413
Score = 35.8 bits (81), Expect = 0.16
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = +3
Query: 555 CVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQND--YQDKIRLVLKK 704
CV CG TPLW+R+R G +C + CG H+ QN + K R+++ K
Sbjct: 204 CVNCGATATPLWRRDRTG--HYLC-NACGLYHKMNGQNRPLIRPKKRMIVSK 252
>sp|P17678|GATA1_CHICK Erythroid transcription factor (GATA-binding factor 1) (GATA-1)
(Eryf1) (NF-E1 DNA-binding protein) (NF-E1A)
Length = 304
Score = 35.4 bits (80), Expect = 0.21
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Frame = +3
Query: 555 CVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQND--YQDKIRLVLKK 704
CV CG TPLW+R+ G+ +C + CG HR QN + K RL++ K
Sbjct: 110 CVNCGATATPLWRRD--GTGHYLC-NACGLYHRLNGQNRPLIRPKKRLLVSK 158
>sp|P23768|GAT1B_XENLA GATA-binding factor 1-B (Transcription factor xGATA-1B)
Length = 364
Score = 34.7 bits (78), Expect = 0.36
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +3
Query: 555 CVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQND--YQDKIRLVLKK 704
CV CG TPLW+R+ G +C + CG H+ QN + K RL++ K
Sbjct: 180 CVNCGATVTPLWRRDLSG--HYLC-NACGLYHKMNGQNRPLIRPKKRLIISK 228
>sp|P23767|GAT1A_XENLA GATA-binding factor 1-A (Transcription factor xGATA-1A)
Length = 359
Score = 34.7 bits (78), Expect = 0.36
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +3
Query: 555 CVQCGTDFTPLWKRERPGSSKVVCESCCGENHRRALQND--YQDKIRLVLKK 704
CV CG TPLW+R+ G +C + CG H+ QN + K RL++ K
Sbjct: 178 CVNCGATVTPLWRRDMSG--HYLC-NACGLYHKMNGQNRPLIRPKKRLIVSK 226
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,227,241
Number of Sequences: 369166
Number of extensions: 1636216
Number of successful extensions: 6732
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5566
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6623
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8790245790
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)