Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_D06
(606 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondr... 198 8e-51
sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondria... 198 1e-50
sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:g... 196 3e-50
sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondr... 195 7e-50
sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinot... 103 3e-22
sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferas... 101 2e-21
sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferas... 92 1e-18
sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinot... 67 5e-11
sp|P56079|CDSA_DROME Phosphatidate cytidylyltransferase, ph... 34 0.33
sp|Q9UQ07|MOK_HUMAN MAPK/MAK/MRK overlapping kinase (MOK pr... 31 2.1
>sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 198 bits (504), Expect = 8e-51
Identities = 100/188 (53%), Positives = 127/188 (67%), Gaps = 7/188 (3%)
Frame = +2
Query: 62 QPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIESPMAWRCRYFEYEAYRPLIRK 241
+P+ ID+ ++ TP F STGLY+AMPRD ++VVG+EIIE+PMAWR R+FEY AYR +I+
Sbjct: 143 RPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKD 202
Query: 242 YFNEGARWTSAPKCTMEEGLYDMKFDVS--QDKPYV-----YVTTELEPCFDAADFTRVG 400
YF+ GA+WT+APK TM + LYD + + +D+ + +VTTE EPCFDAADF R G
Sbjct: 203 YFHRGAKWTTAPKPTMADELYDQNYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAG 262
Query: 401 RDIFGQRSHVTNKKAIQWLRRHLAPRGIRVHDIEFDSLYSMHIDTNFFPVKPGLFLLKDG 580
RDIF QRS VTN I+W+RRHLAP RVH I F MHID F + PGL L
Sbjct: 263 RDIFAQRSQVTNYLGIEWMRRHLAP-DYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPD 321
Query: 581 LNCRTPNL 604
C +L
Sbjct: 322 RPCHQIDL 329
>sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 198 bits (503), Expect = 1e-50
Identities = 100/188 (53%), Positives = 127/188 (67%), Gaps = 7/188 (3%)
Frame = +2
Query: 62 QPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIESPMAWRCRYFEYEAYRPLIRK 241
+P+ ID+ ++ TP F STGLY+AMPRD ++VVG+EIIE+PMAWR R+FEY AYR +I+
Sbjct: 143 RPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKD 202
Query: 242 YFNEGARWTSAPKCTMEEGLYDMKFDVS--QDKPYV-----YVTTELEPCFDAADFTRVG 400
YF+ GA+WT+APK TM + LYD + + +D+ + +VTTE EPCFDAADF R G
Sbjct: 203 YFHRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAG 262
Query: 401 RDIFGQRSHVTNKKAIQWLRRHLAPRGIRVHDIEFDSLYSMHIDTNFFPVKPGLFLLKDG 580
RDIF QRS VTN I+W+RRHLAP RVH I F MHID F + PGL L
Sbjct: 263 RDIFAQRSQVTNYLGIEWMRRHLAP-DYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPD 321
Query: 581 LNCRTPNL 604
C +L
Sbjct: 322 RPCHQIDL 329
>sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:glycine amidinotransferase)
(Transamidinase) (AT)
Length = 386
Score = 196 bits (499), Expect = 3e-50
Identities = 99/188 (52%), Positives = 125/188 (66%), Gaps = 7/188 (3%)
Frame = +2
Query: 62 QPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIESPMAWRCRYFEYEAYRPLIRK 241
+P+ ID+ ++ TP F STGLY AMPRD ++VVG+EIIE+PMAWR R+FEY AYR +I+
Sbjct: 106 RPDPIDWSVKYKTPDFESTGLYGAMPRDILIVVGNEIIEAPMAWRARFFEYRAYRSIIKD 165
Query: 242 YFNEGARWTSAPKCTMEEGLYDMKFDV--SQDKPYV-----YVTTELEPCFDAADFTRVG 400
YF GA+WT+APK TM + LYD + + +D+ + +VTTE EPCFDAADF R G
Sbjct: 166 YFRRGAKWTTAPKPTMADELYDQDYPIYSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAG 225
Query: 401 RDIFGQRSHVTNKKAIQWLRRHLAPRGIRVHDIEFDSLYSMHIDTNFFPVKPGLFLLKDG 580
RDIF QRS VTN I+W+R+HLAP RVH I F MHID F + PGL L
Sbjct: 226 RDIFAQRSQVTNYMGIEWMRKHLAP-DYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPD 284
Query: 581 LNCRTPNL 604
C +L
Sbjct: 285 RPCHQIDL 292
>sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 195 bits (496), Expect = 7e-50
Identities = 98/188 (52%), Positives = 127/188 (67%), Gaps = 7/188 (3%)
Frame = +2
Query: 62 QPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIESPMAWRCRYFEYEAYRPLIRK 241
+P+ ID+ ++ TP F STGLY+AMPRD ++VVG+EIIE+PMAWR R+FEY AYR +I+
Sbjct: 143 RPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKD 202
Query: 242 YFNEGARWTSAPKCTMEEGLYDMKFDVS--QDKPYV-----YVTTELEPCFDAADFTRVG 400
YF+ GA+WT+APK TM + LY+ + + +D+ + +VTTE EPCFDAADF R G
Sbjct: 203 YFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAG 262
Query: 401 RDIFGQRSHVTNKKAIQWLRRHLAPRGIRVHDIEFDSLYSMHIDTNFFPVKPGLFLLKDG 580
RDIF QRS VTN I+W+RRHLAP RVH I F MHID F + PG+ L
Sbjct: 263 RDIFAQRSQVTNYLGIEWMRRHLAP-DYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPD 321
Query: 581 LNCRTPNL 604
C +L
Sbjct: 322 RPCHQIDL 329
>sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 349
Score = 103 bits (257), Expect = 3e-22
Identities = 70/190 (36%), Positives = 94/190 (49%), Gaps = 1/190 (0%)
Frame = +2
Query: 5 EDEIXXXXXXXXXXXXXXXQPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIESP 184
EDE+ +P A D TP + S G PRD +LVVGD +IE+P
Sbjct: 63 EDELEELCEELRGLGVTVRRPGARDSAAPVRTPDWESDGYGDLCPRDGLLVVGDTVIEAP 122
Query: 185 MAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYDMKFDVSQDKPYVYVTTELE 364
MA R R+ E AY+ L+ +Y G+RW SAPK + EG+Y S P +LE
Sbjct: 123 MALRARFLESLAYKELLVEYLAAGSRWISAPKPRLAEGMY------SPSGPSGERLRDLE 176
Query: 365 PCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHLAPRGIRVHDIEFDSLY-SMHIDTNF 541
P FDAA+ R+G D+ S N+ +WL+ L VH LY S HID+
Sbjct: 177 PVFDAANVLRLGTDLLYLVSDSGNELGARWLQSALG-AAYTVHPCR--GLYSSTHIDSTL 233
Query: 542 FPVKPGLFLL 571
P++PGL L+
Sbjct: 234 VPLRPGLVLV 243
>sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 348
Score = 101 bits (251), Expect = 2e-21
Identities = 60/159 (37%), Positives = 86/159 (54%), Gaps = 1/159 (0%)
Frame = +2
Query: 98 TPKFSSTGLYAAMPRDFMLVVGDEIIESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAP 277
TP + + G + PRD +L VG +IESPMA R R+ E AY+ ++ +YF GARW SAP
Sbjct: 93 TPDWQTDGFHDYCPRDGLLAVGQTVIESPMALRARFLESLAYKDILLEYFASGARWLSAP 152
Query: 278 KCTMEEGLYDMKFDVSQDKPYVYVTTELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWL 457
K + + +Y+ Q T+LEP FDAA+ R G D+ S N+ +WL
Sbjct: 153 KPRLADEMYEPTAPAGQR------LTDLEPVFDAANVLRFGTDLLYLVSDSGNELGAKWL 206
Query: 458 RRHLAPRGIRVHDIEFDSLY-SMHIDTNFFPVKPGLFLL 571
+ L +VH LY S H+D+ P++PGL L+
Sbjct: 207 QSALGST-YKVHPCR--GLYASTHVDSTIVPLRPGLVLV 242
>sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 347
Score = 92.0 bits (227), Expect = 1e-18
Identities = 60/170 (35%), Positives = 86/170 (50%), Gaps = 1/170 (0%)
Frame = +2
Query: 62 QPEAIDYDHQWTTPKFSSTGLYAAMPRDFMLVVGDEIIESPMAWRCRYFEYEAYRPLIRK 241
+P D+ TP + + G + PRD +L VG IIE+PMA R R+ E AY+ L+ +
Sbjct: 81 RPGPRDHSALIKTPDWETDGFHDYCPRDGLLSVGQTIIETPMALRSRFLESLAYKDLLLE 140
Query: 242 YFNEGARWTSAPKCTMEEGLYDMKFDVSQDKPYVYVTTELEPCFDAADFTRVGRDIFGQR 421
YF G+RW SAPK + + Y + P T+ EP FDAA+ R G D+
Sbjct: 141 YFASGSRWLSAPKPRLTDDSY------APQAPAGERLTDEEPVFDAANVLRFGTDLLYLV 194
Query: 422 SHVTNKKAIQWLRRHLAPRGIRVHDIEFDSLY-SMHIDTNFFPVKPGLFL 568
S N+ +WL+ + VH LY S H+D+ P++PGL L
Sbjct: 195 SDSGNELGAKWLQSAVGDT-YTVHPCR--KLYASTHVDSTIVPLRPGLVL 241
>sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 319
Score = 66.6 bits (161), Expect = 5e-11
Identities = 49/148 (33%), Positives = 67/148 (45%)
Frame = +2
Query: 128 AAMPRDFMLVVGDEIIESPMAWRCRYFEYEAYRPLIRKYFNEGARWTSAPKCTMEEGLYD 307
A PRD +L VG+ +I++P + A R L+ +YF G+RW SAP + + +YD
Sbjct: 74 AYRPRDGLLTVGETVIQTPAVPGLPSLQSPACRMLLMEYFTSGSRWISAPPPVLTDVMYD 133
Query: 308 MKFDVSQDKPYVYVTTELEPCFDAADFTRVGRDIFGQRSHVTNKKAIQWLRRHLAPRGIR 487
P ELEP FDA R+G D+ S N +WL+ L R
Sbjct: 134 ------PTAPAGERLRELEPVFDADTVLRIGTDLLYLVSDSGNALGARWLQAALGER-YT 186
Query: 488 VHDIEFDSLYSMHIDTNFFPVKPGLFLL 571
VH S H D P+ PGL L+
Sbjct: 187 VHPCR-GPHGSPHGDFAVVPLGPGLILV 213
>sp|P56079|CDSA_DROME Phosphatidate cytidylyltransferase, photoreceptor-specific
(CDP-diglyceride synthetase) (CDP-diglyceride
pyrophosphorylase) (CDP-diacylglycerol synthase) (CDS)
(CTP:phosphatidate cytidylyltransferase) (CDP-DAG
synthase) (CDP-DG synthetase)
Length = 447
Score = 33.9 bits (76), Expect = 0.33
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Frame = -1
Query: 333 LSW---LTSNFISYKPSSIVHFGAEVHRAPSLKYFLINGRYASYSKYL 199
LSW LTSN+ Y + + +FG ++R LK+ + R+ S++ Y+
Sbjct: 142 LSWYFLLTSNYFFYGENLVDYFGVVINRVEYLKFLVTYHRFLSFALYI 189
>sp|Q9UQ07|MOK_HUMAN MAPK/MAK/MRK overlapping kinase (MOK protein kinase) (Renal tumor
antigen 1) (RAGE-1)
Length = 419
Score = 31.2 bits (69), Expect = 2.1
Identities = 13/38 (34%), Positives = 18/38 (47%)
Frame = +2
Query: 260 RWTSAPKCTMEEGLYDMKFDVSQDKPYVYVTTELEPCF 373
RW AP+C + +G Y K D+ Y L+P F
Sbjct: 165 RWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLF 202
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,972,117
Number of Sequences: 369166
Number of extensions: 1447632
Number of successful extensions: 3254
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3183
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3238
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4699949280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)