Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_A24
(839 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP... 231 1e-60
sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP I... 226 8e-59
sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP... 219 7e-57
sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precur... 147 3e-35
sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precur... 147 4e-35
sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precur... 142 1e-33
sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor 123 6e-28
sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor 105 1e-22
sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor 58 4e-08
sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor 57 6e-08
>sp|Q9ET22|DPP2_MOUSE Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 506
Score = 231 bits (590), Expect = 1e-60
Identities = 119/258 (46%), Positives = 167/258 (64%)
Frame = +3
Query: 3 DGFGQMRYLATQGQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATN 182
D F Q++ L QG + IS+ TC+ L+S D+ + RN F +LAMMDYPY T+
Sbjct: 232 DAFQQIKDLFLQG--AYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTD 289
Query: 183 FMGNLPAHPVRVACQNILANKDNSIVALREAGAVYYNTSQTSTCFSPFDLYIECSDITGC 362
F+G LPA+PV+V CQ +L N+ I+ LR + YN+S T C+ + LY C+D TGC
Sbjct: 290 FLGPLPANPVKVGCQRLL-NEGQRIMGLRALAGLVYNSSGTEPCYDIYRLYQSCADPTGC 348
Query: 363 GLGPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKY 542
G G D+ AWD+QACTE+ L DSN + DMFP++P + + ++C+ + V + L+
Sbjct: 349 GTGSDARAWDYQACTEINLTFDSNNVT-DMFPEIPFSEELRQQYCLDTWGVWPRQDWLQT 407
Query: 543 LEWGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADP 722
WG ++ A+NIIFSNGDLDPW+ GGI N L +S +A+ I+GGAHHLDLR+SN DP
Sbjct: 408 SFWGGDLKAASNIIFSNGDLDPWAGGGIQSN--LSTSVIAVTIQGGAHHLDLRASNSEDP 465
Query: 723 PSVQQARQSEEFYIRKWL 776
PSV + R+ E IR+W+
Sbjct: 466 PSVVEVRKLESTLIREWV 483
>sp|Q9EPB1|DPP2_RAT Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 500
Score = 226 bits (575), Expect = 8e-59
Identities = 116/258 (44%), Positives = 166/258 (64%)
Frame = +3
Query: 3 DGFGQMRYLATQGQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATN 182
D F Q++ L QG + IS+ TC+ L+S D+ + RN F +LAMMDYPY TN
Sbjct: 232 DAFQQIKDLFLQG--AYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTN 289
Query: 183 FMGNLPAHPVRVACQNILANKDNSIVALREAGAVYYNTSQTSTCFSPFDLYIECSDITGC 362
F+G LPA+PV+V C+ +L ++ I+ LR + YN+S CF + +Y C+D TGC
Sbjct: 290 FLGPLPANPVKVGCERLL-SEGQRIMGLRALAGLVYNSSGMEPCFDIYQMYQSCADPTGC 348
Query: 363 GLGPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKY 542
G G ++ AWD+QACTE+ L DSN + DMFP++P + + ++C+ + V + L+
Sbjct: 349 GTGSNARAWDYQACTEINLTFDSNNVT-DMFPEIPFSDELRQQYCLDTWGVWPRPDWLQT 407
Query: 543 LEWGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADP 722
WG ++ A+NIIFSNGDLDPW+ GGI N L +S +A+ I+GGAHHLDLR+SN DP
Sbjct: 408 SFWGGDLKAASNIIFSNGDLDPWAGGGIQRN--LSTSIIAVTIQGGAHHLDLRASNSEDP 465
Query: 723 PSVQQARQSEEFYIRKWL 776
PSV + R+ E IR+W+
Sbjct: 466 PSVVEVRKLEATLIREWV 483
>sp|Q9UHL4|DPP2_HUMAN Dipeptidyl-peptidase II precursor (DPP II) (Dipeptidyl
aminopeptidase II) (Quiescent cell proline dipeptidase)
(Dipeptidyl peptidase 7)
Length = 492
Score = 219 bits (558), Expect = 7e-57
Identities = 115/258 (44%), Positives = 160/258 (62%)
Frame = +3
Query: 3 DGFGQMRYLATQGQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATN 182
+ F Q++ L QG + + TC+PL+ D+ + RN F +LAMMDYPY T+
Sbjct: 222 EAFRQIKDLFLQG--AYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTD 279
Query: 183 FMGNLPAHPVRVACQNILANKDNSIVALREAGAVYYNTSQTSTCFSPFDLYIECSDITGC 362
F+G LPA+PV+V C +L+ I LR + YN S + C+ + LY C+D TGC
Sbjct: 280 FLGPLPANPVKVGCDRLLSEAQR-ITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGC 338
Query: 363 GLGPDSLAWDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKY 542
G GPD+ AWD+QACTE+ L SN + DMFPDLP T + ++C+ + V + L
Sbjct: 339 GTGPDARAWDYQACTEINLTFASNNVT-DMFPDLPFTDELRQRYCLDTWGVWPRPDWLLT 397
Query: 543 LEWGDYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADP 722
WG +R A+NIIFSNG+LDPW+ GGI N L +S +A+ I+GGAHHLDLR+S+P DP
Sbjct: 398 SFWGGDLRAASNIIFSNGNLDPWAGGGIRRN--LSASVIAVTIQGGAHHLDLRASHPEDP 455
Query: 723 PSVQQARQSEEFYIRKWL 776
SV +AR+ E I +W+
Sbjct: 456 ASVVEARKLEATIIGEWV 473
>sp|Q5RBU7|PCP_PONPY Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase)
Length = 496
Score = 147 bits (372), Expect = 3e-35
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 3/248 (1%)
Frame = +3
Query: 48 GFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQ 227
G Q ++ L C PLTS D+ + W+ +V LAM+DYPYA+NF+ LPA P++V CQ
Sbjct: 253 GLQWLTGALHLCSPLTS-QDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQ 311
Query: 228 NIL-ANKDNSIVA--LREAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQ 398
+ N +S++ + +A VYYN S C + S+ LG +L W +Q
Sbjct: 312 YLKNPNVSDSLLLQNIFQALNVYYNYSGQVKC-------LNISETATSSLG--TLGWSYQ 362
Query: 399 ACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRTATN 578
ACTE+ + +N DMF +++ C +++ V + + + G + + TN
Sbjct: 363 ACTEVVMPFCTNGVD-DMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTN 421
Query: 579 IIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEF 758
I+FSNG+LDPWS GG+T++ + + VA+ I GAHHLDLR+ N DP SV AR E
Sbjct: 422 IVFSNGELDPWSGGGVTKD--ITDTLVAVTISEGAHHLDLRTKNALDPTSVLLARSLEVR 479
Query: 759 YIRKWLNE 782
+++ W+ +
Sbjct: 480 HMKNWIRD 487
>sp|P42785|PCP_HUMAN Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase) (Angiotensinase C)
(Lysosomal carboxypeptidase C)
Length = 496
Score = 147 bits (371), Expect = 4e-35
Identities = 89/248 (35%), Positives = 138/248 (55%), Gaps = 3/248 (1%)
Frame = +3
Query: 48 GFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQ 227
G Q ++ L C PLTS D+ + W+ +V LAM+DYPYA+NF+ LPA P++V CQ
Sbjct: 253 GLQWLTGALHLCSPLTS-QDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQ 311
Query: 228 NIL-ANKDNSIVA--LREAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQ 398
+ N +S++ + +A VYYN S C + S+ LG +L W +Q
Sbjct: 312 YLKNPNVSDSLLLQNIFQALNVYYNYSGQVKC-------LNISETATSSLG--TLGWSYQ 362
Query: 399 ACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRTATN 578
ACTE+ + +N DMF +++ C +++ V + + + G + + TN
Sbjct: 363 ACTEVVMPFCTNGVD-DMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTN 421
Query: 579 IIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEF 758
I+FSNG+LDPWS GG+T++ + + VA+ I GAHHLDLR+ N DP SV AR E
Sbjct: 422 IVFSNGELDPWSGGGVTKD--ITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVR 479
Query: 759 YIRKWLNE 782
+++ W+ +
Sbjct: 480 HMKNWIRD 487
>sp|Q7TMR0|PCP_MOUSE Lysosomal Pro-X carboxypeptidase precursor (Prolylcarboxypeptidase)
(PRCP) (Proline carboxypeptidase)
Length = 491
Score = 142 bits (358), Expect = 1e-33
Identities = 89/246 (36%), Positives = 131/246 (53%), Gaps = 3/246 (1%)
Frame = +3
Query: 48 GFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQ 227
G Q ++ L C PLTS + W+ +V LAM++YPYA NF+ LPA P++ CQ
Sbjct: 251 GLQSLTNILHLCSPLTS-EKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQ 309
Query: 228 NILANKDNSIVALR---EAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQ 398
+ + V L+ +A +VYYN S + C + S T LG S+ W FQ
Sbjct: 310 YLKNPNVSDTVLLQNIFQALSVYYNYSGQAAC-------LNISQTTTSSLG--SMGWSFQ 360
Query: 399 ACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRTATN 578
ACTEM + +N DMF ++ C ++ V + + + G + + +N
Sbjct: 361 ACTEMVMPFCTNGID-DMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSN 419
Query: 579 IIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEF 758
IIFSNG+LDPWS GG+T + + + VA+ I GAHHLDLR+ N DP SV +R E
Sbjct: 420 IIFSNGELDPWSGGGVTRD--ITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVK 477
Query: 759 YIRKWL 776
+++KW+
Sbjct: 478 HMKKWI 483
>sp|P34676|YO26_CAEEL Putative serine protease Z688.6 precursor
Length = 507
Score = 123 bits (309), Expect = 6e-28
Identities = 83/263 (31%), Positives = 132/263 (50%), Gaps = 15/263 (5%)
Frame = +3
Query: 39 GQQGFQLISKYLKTCKPLTSISDVNYAMKWLRNGFVMLAMMDYPYATNFMGNLPAHPVRV 218
G+Q ++ K L L + D+ + +++R +AM++YPY T+F+ +LPA PV+
Sbjct: 246 GRQYLNVLYK-LDPKSKLENKDDIGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKE 304
Query: 219 ACQNILA---NKDNSIVALREAGAVYYN-TSQTSTCFSPFDLYIECSDITGC----GLGP 374
AC++ ++ S L + +YYN T ST C++ C G
Sbjct: 305 ACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKST---------HCANAAKCDSAYGSLG 355
Query: 375 DSLAWDFQACTEMKLYDDSNATSGDMF-PDLPLTRQQVDKHCIKKFE-VDRADNQLKYLE 548
D L W FQ CTEM + + D F D P T ++ + C++ F + L+ L
Sbjct: 356 DPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLA 415
Query: 549 WG-----DYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNP 713
G + +A+NI+FSNG LDPWS GG + + S +++ +K GAHH DLR ++P
Sbjct: 416 GGLAFGATSLPSASNIVFSNGYLDPWSGGGYDHSDKVQGSVISVILKQGAHHYDLRGAHP 475
Query: 714 ADPPSVQQARQSEEFYIRKWLNE 782
D V++ R E I+KW+ E
Sbjct: 476 QDTEEVKKVRAMETQAIKKWIKE 498
>sp|P34610|PCP1_CAEEL Putative serine protease pcp-1 precursor
Length = 565
Score = 105 bits (263), Expect = 1e-22
Identities = 77/233 (33%), Positives = 114/233 (48%), Gaps = 13/233 (5%)
Frame = +3
Query: 126 WLRNGFVMLAMMDYPYATNFMGNLPAHPVRVACQNILAN----KDNSIV-ALREAGAVYY 290
+LR +AM+DYPY T F+ LPA PV VAC + AN D +V A+ A +YY
Sbjct: 281 YLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACGYMNANGTSFSDKDLVKAVANAANIYY 340
Query: 291 NTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQACTEMKLYDDSNATSGDMF----- 455
N ++ D I C D GLG D L W +Q C+E+ + ++ S D+F
Sbjct: 341 NYNRDPNFTYCIDFSI-CGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECG 399
Query: 456 PDLPLTRQQVDKHCIKKFEVDRADNQLKYLE--WGDYVRTATNIIFSNGDLDPWSLGGIT 629
D+ T QQ K + + ++ +G + ++N+I + G LDPWS GG
Sbjct: 400 KDIYQTLQQGCVSIFKSMGWTPKNWNIDAVKTLYGYDLSGSSNLILTQGHLDPWSGGGYK 459
Query: 630 ENASLPSSSV-ALWIKGGAHHLDLRSSNPADPPSVQQARQSEEFYIRKWLNEN 785
+ + + + L I G AHHLDLR N DP +V AR ++ W++ N
Sbjct: 460 VDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNARFQIIQILKCWVDPN 512
>sp|Q9NQE7|TSSP_HUMAN Thymus-specific serine protease precursor
Length = 514
Score = 57.8 bits (138), Expect = 4e-08
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
Frame = +3
Query: 387 WDFQACTEMKLYDDSNATSGDMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLE----WG 554
W +Q CTE Y F LP Q+D C + F + + +G
Sbjct: 373 WLYQTCTEFGFYVTCENPRCP-FSQLPALPSQLDL-CEQVFGLSALSVAQAVAQTNSYYG 430
Query: 555 DYVRTATNIIFSNGDLDPWSLGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQ 734
A ++F NGD DPW + +T+ +L SS L I+ G+H LD+ P+D PS++
Sbjct: 431 GQTPGANKVLFVNGDTDPWHVLSVTQ--ALGSSESTLLIRTGSHCLDMAPERPSDSPSLR 488
Query: 735 QARQSEEFYIRKWL 776
RQ+ ++ WL
Sbjct: 489 LGRQNIFQQLQTWL 502
>sp|Q9QXE5|TSSP_MOUSE Thymus-specific serine protease precursor
Length = 509
Score = 57.0 bits (136), Expect = 6e-08
Identities = 46/176 (26%), Positives = 70/176 (39%), Gaps = 4/176 (2%)
Frame = +3
Query: 267 REAGAVYYNTSQTSTCFSPFDLYIECSDITGCGLGPDSLAWDFQACTEMKLYDDSNATSG 446
R V + Q FS + + S+ G W +Q CTE Y
Sbjct: 332 RAVQIVLRSMGQKCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQC 391
Query: 447 DMFPDLPLTRQQVDKHCIKKFEVDRADNQLKYLEWGDYVRT----ATNIIFSNGDLDPWS 614
F LP Q++ C + F + A + Y AT ++F NGD DPW
Sbjct: 392 P-FSQLPALPFQLEL-CEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWH 449
Query: 615 LGGITENASLPSSSVALWIKGGAHHLDLRSSNPADPPSVQQARQSEEFYIRKWLNE 782
+ +T++ L S AL I +H D+ P+D PS++ RQ ++ WL +
Sbjct: 450 VLSVTQDLGL--SEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKD 503
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,336,605
Number of Sequences: 369166
Number of extensions: 2024877
Number of successful extensions: 4743
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4564
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4714
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8197207050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)