Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_A10
(872 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:g... 233 7e-61
sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondr... 232 9e-61
sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondr... 230 3e-60
sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondria... 229 1e-59
sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferas... 108 3e-23
sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferas... 102 1e-21
sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinot... 102 1e-21
sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinot... 57 7e-08
sp|Q5HCR2|ARCA_STAAC Arginine deiminase (ADI) (Arginine dih... 33 1.4
sp|Q6GDG7|ARCA_STAAR Arginine deiminase (ADI) (Arginine dih... 33 1.4
>sp|P50441|GATM_PIG Glycine amidinotransferase (L-arginine:glycine amidinotransferase)
(Transamidinase) (AT)
Length = 386
Score = 233 bits (593), Expect = 7e-61
Identities = 126/262 (48%), Positives = 170/262 (64%), Gaps = 5/262 (1%)
Frame = +2
Query: 98 KNSPVWSWNEWDPLEEVIXXXXXXXXXXXXXXETAACFGERLTENFMKKYGGQYWSDIMP 277
K+ PV S+NEWDPLEEVI E A E+ F +KYGG Y+ P
Sbjct: 25 KDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWP-FYQKYGGHYF----P 79
Query: 278 KEVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILVVG 457
K+ + + E +E NILK EGV V P+P+D +Y+TP F+S GL A PRDI++VVG
Sbjct: 80 KDHLKKAVAEIEEMCNILKMEGVTVRRPDPIDWSVKYKTPDFESTGLYGAMPRDILIVVG 139
Query: 458 DEIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDI----SGN 625
+EI+E M WR+RF+EY YR ++ DY+RRGA + +APKP +++ + +++ I +
Sbjct: 140 NEIIEAPMAWRARFFEYRAYRSIIKDYFRRGAKWTTAPKPTMADELYDQDYPIYSVEDRH 199
Query: 626 KFDELG-YVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEKGIRLHLLN 802
K G +VTTEFEP FDAADF+RAGRDIF Q+S VTN GIEWMR+HLA R+H+++
Sbjct: 200 KLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYMGIEWMRKHLA-PDYRVHIIS 258
Query: 803 FHDPYAMHIDATFFTVKPGYLI 868
F DP MHIDATF + PG ++
Sbjct: 259 FKDPNPMHIDATFNIIGPGLVL 280
>sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 232 bits (592), Expect = 9e-61
Identities = 134/295 (45%), Positives = 179/295 (60%), Gaps = 8/295 (2%)
Frame = +2
Query: 8 VYKTSVSTNQIVLSNITHRNCCT---KTKVENKKNSPVWSWNEWDPLEEVIXXXXXXXXX 178
V +T ST S+ RN C K K+ PV S+NEWDPLEEVI
Sbjct: 32 VQRTFQSTQAATASS---RNSCAADDKATEPLPKDCPVSSYNEWDPLEEVIVGRAENACV 88
Query: 179 XXXXXETAACFGERLTENFMKKYGGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVH 358
E A E+ F +K GG Y+ PK+ + + E +E NILK EGV V
Sbjct: 89 PPFTIEVKANTYEKYWP-FYQKQGGHYF----PKDHLKKAVAEIEEMCNILKTEGVTVRR 143
Query: 359 PEPMDMKKEYETPYFKSVGLDCAFPRDIILVVGDEIMETTMTWRSRFWEYLCYRPLMLDY 538
P+P+D +Y+TP F+S GL A PRDI++VVG+EI+E M WRSRF+EY YR ++ DY
Sbjct: 144 PDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDY 203
Query: 539 WRRGANFQSAPKPVCSEQSFKKNFDISG----NKFDELG-YVTTEFEPMFDAADFMRAGR 703
+ RGA + +APKP +++ + +++ I +K G +VTTEFEP FDAADF+RAGR
Sbjct: 204 FHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGR 263
Query: 704 DIFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHDPYAMHIDATFFTVKPGYLI 868
DIF Q+S VTN GIEWMR+HLA R+H+++F DP MHIDATF + PG ++
Sbjct: 264 DIFAQRSQVTNYLGIEWMRRHLA-PDYRVHIISFKDPNPMHIDATFNIIGPGIVL 317
>sp|Q9D964|GATM_MOUSE Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 230 bits (587), Expect = 3e-60
Identities = 132/294 (44%), Positives = 179/294 (60%), Gaps = 7/294 (2%)
Frame = +2
Query: 8 VYKTSVSTNQIVLSNITHRNCCTKTKVENK--KNSPVWSWNEWDPLEEVIXXXXXXXXXX 181
V +T ST S+ +C + K + K+ PV S+NEWDPLEEVI
Sbjct: 32 VQRTFQSTQAATASS--RNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVP 89
Query: 182 XXXXETAACFGERLTENFMKKYGGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHP 361
E A E+ F +K GG Y+ PK+ + + E +E NIL EGV V P
Sbjct: 90 PFTVEVKANTYEKYWP-FYQKNGGLYF----PKDHLKKAVAEVEEMCNILSMEGVTVRRP 144
Query: 362 EPMDMKKEYETPYFKSVGLDCAFPRDIILVVGDEIMETTMTWRSRFWEYLCYRPLMLDYW 541
+P+D +Y+TP F+S GL A PRDI++VVG+EI+E M WRSRF+EY YR ++ DY+
Sbjct: 145 DPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYF 204
Query: 542 RRGANFQSAPKPVCSEQSFKKNFDISG----NKFDELG-YVTTEFEPMFDAADFMRAGRD 706
RGA + +APKP +++ + +N+ I +K G +VTTEFEP FDAADF+RAGRD
Sbjct: 205 HRGAKWTTAPKPTMADELYDQNYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRD 264
Query: 707 IFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHDPYAMHIDATFFTVKPGYLI 868
IF Q+S VTN GIEWMR+HLA R+H+++F DP MHIDATF + PG ++
Sbjct: 265 IFAQRSQVTNYLGIEWMRRHLA-PDYRVHIISFKDPNPMHIDATFNIIGPGLVL 317
>sp|P50442|GATM_RAT Glycine amidinotransferase, mitochondrial precursor
(L-arginine:glycine amidinotransferase) (Transamidinase)
(AT)
Length = 423
Score = 229 bits (583), Expect = 1e-59
Identities = 131/294 (44%), Positives = 179/294 (60%), Gaps = 7/294 (2%)
Frame = +2
Query: 8 VYKTSVSTNQIVLSNITHRNCCTKTKVENK--KNSPVWSWNEWDPLEEVIXXXXXXXXXX 181
V +T ST S+ +C + K + K+ PV S+NEWDPLEEVI
Sbjct: 32 VQRTFQSTQAATASS--QNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVP 89
Query: 182 XXXXETAACFGERLTENFMKKYGGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHP 361
E A E+ F +K GG Y+ PK+ + + E +E NIL EGV V P
Sbjct: 90 PFTVEVKANTYEKYWP-FYQKNGGLYF----PKDHLKKAVAEVEEMCNILSMEGVTVKRP 144
Query: 362 EPMDMKKEYETPYFKSVGLDCAFPRDIILVVGDEIMETTMTWRSRFWEYLCYRPLMLDYW 541
+P+D +Y+TP F+S GL A PRDI++VVG+EI+E M WRSRF+EY YR ++ DY+
Sbjct: 145 DPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYF 204
Query: 542 RRGANFQSAPKPVCSEQSFKKNFDISG----NKFDELG-YVTTEFEPMFDAADFMRAGRD 706
RGA + +APKP +++ + +++ I +K G +VTTEFEP FDAADF+RAGRD
Sbjct: 205 HRGAKWTTAPKPTMADELYDQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRD 264
Query: 707 IFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHDPYAMHIDATFFTVKPGYLI 868
IF Q+S VTN GIEWMR+HLA R+H+++F DP MHIDATF + PG ++
Sbjct: 265 IFAQRSQVTNYLGIEWMRRHLA-PDYRVHIISFKDPNPMHIDATFNIIGPGLVL 317
>sp|P08078|STRB1_STRGR Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 347
Score = 108 bits (269), Expect = 3e-23
Identities = 81/259 (31%), Positives = 123/259 (47%), Gaps = 10/259 (3%)
Frame = +2
Query: 122 NEWDPLEEVIXXXXXXXXXXXXXXETAACFGERLTEN----FMKKYGGQYWS-DIMPKEV 286
NEWDPLEEVI G R+ F +Y G Y S + +P
Sbjct: 8 NEWDPLEEVI---------------VGTAVGARVPTADRSVFAVEYAGDYESQEQIPSGA 52
Query: 287 WQN-VLKEHQEFVNILKGE----GVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILV 451
+ + VLKE +E +++L E GV V P P D +TP +++ G PRD +L
Sbjct: 53 YPDRVLKETEEELHVLAAELTKLGVTVRRPGPRDHSALIKTPDWETDGFHDYCPRDGLLS 112
Query: 452 VGDEIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKF 631
VG I+ET M RSRF E L Y+ L+L+Y+ G+ + SAPKP ++ S+
Sbjct: 113 VGQTIIETPMALRSRFLESLAYKDLLLEYFASGSRWLSAPKPRLTDDSYAPQAPAGERLT 172
Query: 632 DELGYVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHD 811
DE EP+FDAA+ +R G D+ S N G +W++ + + +
Sbjct: 173 DE--------EPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSAVGDTYTVHPCRKLY- 223
Query: 812 PYAMHIDATFFTVKPGYLI 868
+ H+D+T ++PG ++
Sbjct: 224 -ASTHVDSTIVPLRPGLVL 241
>sp|Q54258|STRB1_STRGA Inosamine-phosphate amidinotransferase I (Aminocyclitol
amidinotransferase) (ADT)
Length = 348
Score = 102 bits (255), Expect = 1e-21
Identities = 79/260 (30%), Positives = 124/260 (47%), Gaps = 11/260 (4%)
Frame = +2
Query: 122 NEWDPLEEVIXXXXXXXXXXXXXXETAACFGERLTEN----FMKKYGGQYWS-DIMPKEV 286
NEWDPLEE+I G R+ F +Y +Y S D +P
Sbjct: 8 NEWDPLEEII---------------VGTAVGARVPRADRSVFAVEYADEYDSQDQVPAGP 52
Query: 287 WQN-VLKEHQEFVNILKGE----GVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILV 451
+ + VLKE +E +++L E GV V P D TP +++ G PRD +L
Sbjct: 53 YPDRVLKETEEELHVLSEELTKLGVTVRRPGQRDNSALVATPDWQTDGFHDYCPRDGLLA 112
Query: 452 VGDEIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKF 631
VG ++E+ M R+RF E L Y+ ++L+Y+ GA + SAPKP +++ ++
Sbjct: 113 VGQTVIESPMALRARFLESLAYKDILLEYFASGARWLSAPKPRLADEMYEPT-------- 164
Query: 632 DELGYVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHD 811
G T+ EP+FDAA+ +R G D+ S N G +W++ L G +
Sbjct: 165 APAGQRLTDLEPVFDAANVLRFGTDLLYLVSDSGNELGAKWLQSAL---GSTYKVHPCRG 221
Query: 812 PYA-MHIDATFFTVKPGYLI 868
YA H+D+T ++PG ++
Sbjct: 222 LYASTHVDSTIVPLRPGLVL 241
>sp|P29780|STRB2_STRGR Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 349
Score = 102 bits (254), Expect = 1e-21
Identities = 76/256 (29%), Positives = 114/256 (44%), Gaps = 7/256 (2%)
Frame = +2
Query: 122 NEWDPLEEVIXXXXXXXXXXXXXXETAACFG---ERLTENFMKKYGGQYWSDI----MPK 280
NEWDPLEEV+ C G L + + G W ++ P
Sbjct: 8 NEWDPLEEVVVGTARRP-----------CAGPDRSLLAVEYAEYAGPGRWQEVPTGPYPD 56
Query: 281 EVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYFKSVGLDCAFPRDIILVVGD 460
+ E +E L+G GV V P D TP ++S G PRD +LVVGD
Sbjct: 57 RALKETEDELEELCEELRGLGVTVRRPGARDSAAPVRTPDWESDGYGDLCPRDGLLVVGD 116
Query: 461 EIMETTMTWRSRFWEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKFDEL 640
++E M R+RF E L Y+ L+++Y G+ + SAPKP +E + + SG + +L
Sbjct: 117 TVIEAPMALRARFLESLAYKELLVEYLAAGSRWISAPKPRLAEGMYSPS-GPSGERLRDL 175
Query: 641 GYVTTEFEPMFDAADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEKGIRLHLLNFHDPYA 820
EP+FDAA+ +R G D+ S N G W++ L + +
Sbjct: 176 -------EPVFDAANVLRLGTDLLYLVSDSGNELGARWLQSALGAAYTVHPCRGLYS--S 226
Query: 821 MHIDATFFTVKPGYLI 868
HID+T ++PG ++
Sbjct: 227 THIDSTLVPLRPGLVL 242
>sp|Q54264|STRB2_STRGA Putative inosamine-phosphate amidinotransferase II (Aminocyclitol
amidinotransferase) (ADT)
Length = 319
Score = 57.0 bits (136), Expect = 7e-08
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 3/153 (1%)
Frame = +2
Query: 329 LKGEGVKVVHPEPMDMKKEYETPYFKSVGLDCAF---PRDIILVVGDEIMETTMTWRSRF 499
L+G GV V P D P G D A PRD +L VG+ +++T
Sbjct: 43 LRGLGVTVRRLPPQDPASPPAPP---DRGADTALAYRPRDGLLTVGETVIQTPAVPGLPS 99
Query: 500 WEYLCYRPLMLDYWRRGANFQSAPKPVCSEQSFKKNFDISGNKFDELGYVTTEFEPMFDA 679
+ R L+++Y+ G+ + SAP PV + D+ + G E EP+FDA
Sbjct: 100 LQSPACRMLLMEYFTSGSRWISAPPPVLT--------DVMYDPTAPAGERLRELEPVFDA 151
Query: 680 ADFMRAGRDIFVQQSHVTNASGIEWMRQHLAEK 778
+R G D+ S NA G W++ L E+
Sbjct: 152 DTVLRIGTDLLYLVSDSGNALGARWLQAALGER 184
>sp|Q5HCR2|ARCA_STAAC Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
sp|Q8NUK7|ARCA_STAAW Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
sp|Q6G639|ARCA_STAAS Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
Length = 411
Score = 32.7 bits (73), Expect = 1.4
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 227 ENFMKKY-GGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYF 403
EN + Y G + DI EV Q KEH F +L+ EGV+V++ E + + E P
Sbjct: 28 ENLVPDYLDGLLFDDIPYLEVAQ---KEHDHFAQVLREEGVEVLYLEKL-AAESIENPQV 83
Query: 404 KSVGLDCAFPRDIILVVGDE 463
+S +D ++G E
Sbjct: 84 RSEFIDDVLAESKKTILGHE 103
>sp|Q6GDG7|ARCA_STAAR Arginine deiminase (ADI) (Arginine dihydrolase) (AD)
Length = 411
Score = 32.7 bits (73), Expect = 1.4
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 227 ENFMKKY-GGQYWSDIMPKEVWQNVLKEHQEFVNILKGEGVKVVHPEPMDMKKEYETPYF 403
EN + Y G + DI EV Q KEH F +L+ EGV+V++ E + + E P
Sbjct: 28 ENLVPDYLDGLLFDDIPYLEVAQ---KEHDHFAQVLREEGVEVLYLEKL-AAESIENPQV 83
Query: 404 KSVGLDCAFPRDIILVVGDE 463
+S +D ++G E
Sbjct: 84 RSEFIDDVLAESKKTILGHE 103
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,494,088
Number of Sequences: 369166
Number of extensions: 2355548
Number of successful extensions: 5917
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5727
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5894
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)