Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_P05
(290 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P09623|DLDH_PIG Dihydrolipoyl dehydrogenase, mitochondri... 105 4e-23
sp|Q60HG3|DLDH_MACFA Dihydrolipoyl dehydrogenase, mitochond... 102 2e-22
sp|P49819|DLDH_CANFA Dihydrolipoyl dehydrogenase, mitochond... 102 2e-22
sp|P09622|DLDH_HUMAN Dihydrolipoyl dehydrogenase, mitochond... 102 2e-22
sp|O08749|DLDH_MOUSE Dihydrolipoyl dehydrogenase, mitochond... 102 4e-22
sp|O18480|DLDH_MANSE Dihydrolipoyl dehydrogenase (Dihydroli... 98 7e-21
sp|O00087|DLDH_SCHPO Dihydrolipoyl dehydrogenase, mitochond... 93 2e-19
sp|P09624|DLDH_YEAST Dihydrolipoyl dehydrogenase, mitochond... 88 7e-18
sp|P90597|DLDH_TRYCR Dihydrolipoyl dehydrogenase (Dihydroli... 77 2e-14
sp|Q04933|DLDH_TRYBB Dihydrolipoyl dehydrogenase (Dihydroli... 75 4e-14
>sp|P09623|DLDH_PIG Dihydrolipoyl dehydrogenase, mitochondrial precursor
(Dihydrolipoamide dehydrogenase)
Length = 509
Score = 105 bits (261), Expect = 4e-23
Identities = 50/61 (81%), Positives = 57/61 (93%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LGA+I+G AGE+INEAALA+EYGASCEDIARVCHAHPT++EAFREANLAA GKAIN
Sbjct: 449 RVLGAHIIGPGAGEMINEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKAIN 508
Query: 181 F 183
F
Sbjct: 509 F 509
>sp|Q60HG3|DLDH_MACFA Dihydrolipoyl dehydrogenase, mitochondrial precursor
(Dihydrolipoamide dehydrogenase)
Length = 509
Score = 102 bits (255), Expect = 2e-22
Identities = 48/61 (78%), Positives = 57/61 (93%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LGA+I+G AGE++NEAALA+EYGASCEDIARVCHAHPT++EAFREANLAA GK+IN
Sbjct: 449 RVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSIN 508
Query: 181 F 183
F
Sbjct: 509 F 509
>sp|P49819|DLDH_CANFA Dihydrolipoyl dehydrogenase, mitochondrial precursor
(Dihydrolipoamide dehydrogenase)
Length = 509
Score = 102 bits (255), Expect = 2e-22
Identities = 48/61 (78%), Positives = 57/61 (93%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LGA+I+G AGE++NEAALA+EYGASCEDIARVCHAHPT++EAFREANLAA GK+IN
Sbjct: 449 RVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSIN 508
Query: 181 F 183
F
Sbjct: 509 F 509
>sp|P09622|DLDH_HUMAN Dihydrolipoyl dehydrogenase, mitochondrial precursor
(Dihydrolipoamide dehydrogenase) (Glycine cleavage
system L protein)
Length = 509
Score = 102 bits (255), Expect = 2e-22
Identities = 48/61 (78%), Positives = 57/61 (93%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LGA+I+G AGE++NEAALA+EYGASCEDIARVCHAHPT++EAFREANLAA GK+IN
Sbjct: 449 RVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSIN 508
Query: 181 F 183
F
Sbjct: 509 F 509
>sp|O08749|DLDH_MOUSE Dihydrolipoyl dehydrogenase, mitochondrial precursor
(Dihydrolipoamide dehydrogenase)
Length = 509
Score = 102 bits (253), Expect = 4e-22
Identities = 48/61 (78%), Positives = 56/61 (91%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LGA+I+G AGE++NEAALA+EYGASCEDIARVCHAHPT++EAFREANLAA GK IN
Sbjct: 449 RVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAAAFGKPIN 508
Query: 181 F 183
F
Sbjct: 509 F 509
>sp|O18480|DLDH_MANSE Dihydrolipoyl dehydrogenase (Dihydrolipoamide dehydrogenase) (E3)
Length = 497
Score = 97.8 bits (242), Expect = 7e-21
Identities = 45/60 (75%), Positives = 50/60 (83%)
Frame = +1
Query: 4 LLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAINF 183
+LG +I+G GELINEA LA EYGA+ ED+ARVCHAHPT AEA REANLAAYCGK INF
Sbjct: 438 ILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYCGKPINF 497
>sp|O00087|DLDH_SCHPO Dihydrolipoyl dehydrogenase, mitochondrial precursor (DLDH)
(Dihydrolipoamide dehydrogenase)
Length = 511
Score = 92.8 bits (229), Expect = 2e-19
Identities = 41/61 (67%), Positives = 54/61 (88%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
RLLG +++G +AGELI EA LA+EYGAS ED+ARVCHAHPT++EA +EA +AA+CGK+I+
Sbjct: 451 RLLGVHMIGPMAGELIGEATLALEYGASAEDVARVCHAHPTLSEATKEAMMAAWCGKSIH 510
Query: 181 F 183
F
Sbjct: 511 F 511
>sp|P09624|DLDH_YEAST Dihydrolipoyl dehydrogenase, mitochondrial precursor
(Dihydrolipoamide dehydrogenase)
Length = 499
Score = 87.8 bits (216), Expect = 7e-18
Identities = 42/60 (70%), Positives = 53/60 (88%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LGA+I+G AGE+I EA LA+EYGAS ED+ARVCHAHPT++EAF+EAN+AAY KAI+
Sbjct: 440 RILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAY-DKAIH 498
>sp|P90597|DLDH_TRYCR Dihydrolipoyl dehydrogenase (Dihydrolipoamide dehydrogenase)
Length = 477
Score = 76.6 bits (187), Expect = 2e-14
Identities = 38/61 (62%), Positives = 46/61 (75%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LG +IV + AGELI EA LAMEYGAS ED+ R CHAHPT++EA +EA + A K IN
Sbjct: 418 RILGVHIVCTTAGELIGEACLAMEYGASSEDVGRTCHAHPTMSEALKEACM-ALVAKTIN 476
Query: 181 F 183
F
Sbjct: 477 F 477
>sp|Q04933|DLDH_TRYBB Dihydrolipoyl dehydrogenase (Dihydrolipoamide dehydrogenase)
Length = 479
Score = 75.5 bits (184), Expect = 4e-14
Identities = 38/61 (62%), Positives = 46/61 (75%)
Frame = +1
Query: 1 RLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCGKAIN 180
R+LG +IV S AGELI A LAMEYGAS ED+ R CHAHPT++EA +EA +A + K IN
Sbjct: 420 RILGVHIVCSAAGELIAGALLAMEYGASSEDVGRTCHAHPTMSEAVKEACMACF-AKTIN 478
Query: 181 F 183
F
Sbjct: 479 F 479
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,655,546
Number of Sequences: 369166
Number of extensions: 379172
Number of successful extensions: 776
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 769
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 776
length of database: 68,354,980
effective HSP length: 66
effective length of database: 56,162,470
effective search space used: 1684874100
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)