Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_P04
(545 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P63331|P2AA_RAT Serine/threonine protein phosphatase 2A,... 283 2e-76
sp|P67775|P2AA_HUMAN Serine/threonine protein phosphatase 2... 283 2e-76
sp|P23696|P2A_DROME Serine/threonine protein phosphatase PP... 280 1e-75
sp|P48463|P2AA_CHICK Serine/threonine protein phosphatase 2... 280 2e-75
sp|P11611|P2AB_RABIT Serine/threonine protein phosphatase 2... 279 4e-75
sp|P62714|P2AB_HUMAN Serine/threonine protein phosphatase 2... 279 4e-75
sp|P48580|P2A1_NEUCR Serine/threonine protein phosphatase P... 266 3e-71
sp|O04951|P2A5_ARATH Serine/threonine protein phosphatase P... 261 8e-70
sp|P11493|P2AB_PIG Serine/threonine protein phosphatase 2A,... 261 8e-70
sp|Q07099|P2A2_ARATH Serine/threonine protein phosphatase P... 260 1e-69
>sp|P63331|P2AA_RAT Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P63330|P2AA_MOUSE Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 283 bits (724), Expect = 2e-76
Identities = 135/149 (90%), Positives = 142/149 (95%)
Frame = +2
Query: 98 KDLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLME 277
K+LDQWIEQL + KQLSESQVK LCE AKEIL KESNVQ V+CPVTVCGDVHGQFHDLME
Sbjct: 8 KELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLME 67
Query: 278 LFKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVY 457
LF+IGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVR+++RITILRGNHESRQITQVY
Sbjct: 68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVY 127
Query: 458 GFYDECLRKYTNANVWKYFTDLFDYLPLT 544
GFYDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 128 GFYDECLRKYGNANVWKYFTDLFDYLPLT 156
>sp|P67775|P2AA_HUMAN Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha) (Replication protein C) (RP-C)
sp|P67774|P2AA_BOVIN Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P67777|P2AA_RABIT Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
sp|P67776|P2AA_PIG Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 283 bits (724), Expect = 2e-76
Identities = 135/149 (90%), Positives = 142/149 (95%)
Frame = +2
Query: 98 KDLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLME 277
K+LDQWIEQL + KQLSESQVK LCE AKEIL KESNVQ V+CPVTVCGDVHGQFHDLME
Sbjct: 8 KELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLME 67
Query: 278 LFKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVY 457
LF+IGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVR+++RITILRGNHESRQITQVY
Sbjct: 68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVY 127
Query: 458 GFYDECLRKYTNANVWKYFTDLFDYLPLT 544
GFYDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 128 GFYDECLRKYGNANVWKYFTDLFDYLPLT 156
>sp|P23696|P2A_DROME Serine/threonine protein phosphatase PP2A (Microtubule star
protein)
Length = 309
Score = 280 bits (717), Expect = 1e-75
Identities = 132/149 (88%), Positives = 142/149 (95%)
Frame = +2
Query: 98 KDLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLME 277
KDLDQWIEQL + QL+E+QV+ LC+ AKEIL+KESNVQ VKCPVTVCGDVHGQFHDLME
Sbjct: 8 KDLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLME 67
Query: 278 LFKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVY 457
LF+IGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVR+++RITILRGNHESRQITQVY
Sbjct: 68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVY 127
Query: 458 GFYDECLRKYTNANVWKYFTDLFDYLPLT 544
GFYDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 128 GFYDECLRKYGNANVWKYFTDLFDYLPLT 156
>sp|P48463|P2AA_CHICK Serine/threonine protein phosphatase 2A, catalytic subunit, alpha
isoform (PP2A-alpha)
Length = 309
Score = 280 bits (715), Expect = 2e-75
Identities = 133/149 (89%), Positives = 141/149 (94%)
Frame = +2
Query: 98 KDLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLME 277
K+LDQWIEQL + +QLSESQV+ LCE AKEIL KESNVQ V+CPVTVCGDVHGQFHDLME
Sbjct: 8 KELDQWIEQLNECRQLSESQVRSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLME 67
Query: 278 LFKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVY 457
LF+IGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVR+ +RITILRGNHESRQITQVY
Sbjct: 68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVY 127
Query: 458 GFYDECLRKYTNANVWKYFTDLFDYLPLT 544
GFYDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 128 GFYDECLRKYGNANVWKYFTDLFDYLPLT 156
>sp|P11611|P2AB_RABIT Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 309
Score = 279 bits (713), Expect = 4e-75
Identities = 131/149 (87%), Positives = 141/149 (94%)
Frame = +2
Query: 98 KDLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLME 277
K+LDQW+EQL + KQL+E+QV+ LCE AKEIL KESNVQ V+CPVTVCGDVHGQFHDLME
Sbjct: 8 KELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLME 67
Query: 278 LFKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVY 457
LF+IGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVR+ +RITILRGNHESRQITQVY
Sbjct: 68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVY 127
Query: 458 GFYDECLRKYTNANVWKYFTDLFDYLPLT 544
GFYDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 128 GFYDECLRKYGNANVWKYFTDLFDYLPLT 156
>sp|P62714|P2AB_HUMAN Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
sp|P62716|P2AB_RAT Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
sp|P62715|P2AB_MOUSE Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 309
Score = 279 bits (713), Expect = 4e-75
Identities = 131/149 (87%), Positives = 141/149 (94%)
Frame = +2
Query: 98 KDLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLME 277
K+LDQW+EQL + KQL+E+QV+ LCE AKEIL KESNVQ V+CPVTVCGDVHGQFHDLME
Sbjct: 8 KELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLME 67
Query: 278 LFKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVY 457
LF+IGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVR+ +RITILRGNHESRQITQVY
Sbjct: 68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVY 127
Query: 458 GFYDECLRKYTNANVWKYFTDLFDYLPLT 544
GFYDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 128 GFYDECLRKYGNANVWKYFTDLFDYLPLT 156
>sp|P48580|P2A1_NEUCR Serine/threonine protein phosphatase PP2A catalytic subunit
Length = 327
Score = 266 bits (679), Expect = 3e-71
Identities = 125/147 (85%), Positives = 134/147 (91%)
Frame = +2
Query: 104 LDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLMELF 283
LD WIE L + KQL+ES V+ LCE A+E+L ESNVQPVKCPVTVCGD+HGQFHDLMELF
Sbjct: 28 LDGWIESLMNCKQLAESDVQRLCEKAREVLQDESNVQPVKCPVTVCGDIHGQFHDLMELF 87
Query: 284 KIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGF 463
KIGG PDTNYLFMGDYVDRGYYSVETVTLLVALK+R+ +RITILRGNHESRQITQVYGF
Sbjct: 88 KIGGSCPDTNYLFMGDYVDRGYYSVETVTLLVALKIRYPNRITILRGNHESRQITQVYGF 147
Query: 464 YDECLRKYTNANVWKYFTDLFDYLPLT 544
YDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 148 YDECLRKYGNANVWKYFTDLFDYLPLT 174
>sp|O04951|P2A5_ARATH Serine/threonine protein phosphatase PP2A-5 catalytic subunit
Length = 307
Score = 261 bits (667), Expect = 8e-70
Identities = 122/148 (82%), Positives = 138/148 (93%)
Frame = +2
Query: 101 DLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLMEL 280
D+D+ IEQL + K LSE++VK+LCE AK IL +E NVQPVKCPVTVCGD+HGQF+DL+EL
Sbjct: 7 DIDRQIEQLMECKALSETEVKMLCEHAKTILVEEYNVQPVKCPVTVCGDIHGQFYDLIEL 66
Query: 281 FKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYG 460
F+IGG SPDTNYLFMGDYVDRGYYSVETV+LLVALKVR++DR+TILRGNHESRQITQVYG
Sbjct: 67 FRIGGSSPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRDRLTILRGNHESRQITQVYG 126
Query: 461 FYDECLRKYTNANVWKYFTDLFDYLPLT 544
FYDECLRKY NANVWK+FTDLFDYLPLT
Sbjct: 127 FYDECLRKYGNANVWKHFTDLFDYLPLT 154
>sp|P11493|P2AB_PIG Serine/threonine protein phosphatase 2A, catalytic subunit, beta
isoform (PP2A-beta)
Length = 293
Score = 261 bits (667), Expect = 8e-70
Identities = 124/140 (88%), Positives = 132/140 (94%)
Frame = +2
Query: 125 LYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLMELFKIGGKSP 304
L + KQL+E+QV+ LCE AKEIL KESNVQ V+CPVTVCGDVHGQFHDLMELF+IGGKSP
Sbjct: 1 LNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSP 60
Query: 305 DTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYGFYDECLRK 484
DTNYLFMGDYVDRGYYSVETVTLLVALKVR+ +RITILRGNHESRQITQVYGFYDECLRK
Sbjct: 61 DTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRK 120
Query: 485 YTNANVWKYFTDLFDYLPLT 544
Y NANVWKYFTDLFDYLPLT
Sbjct: 121 YGNANVWKYFTDLFDYLPLT 140
>sp|Q07099|P2A2_ARATH Serine/threonine protein phosphatase PP2A-2 catalytic subunit
Length = 306
Score = 260 bits (665), Expect = 1e-69
Identities = 121/148 (81%), Positives = 136/148 (91%)
Frame = +2
Query: 101 DLDQWIEQLYDNKQLSESQVKVLCETAKEILAKESNVQPVKCPVTVCGDVHGQFHDLMEL 280
DLD+ IEQL + K L E+ VK+LC+ AK IL +E NVQPVKCPVTVCGD+HGQF+DL+EL
Sbjct: 6 DLDRQIEQLMECKPLGEADVKILCDQAKAILVEEYNVQPVKCPVTVCGDIHGQFYDLIEL 65
Query: 281 FKIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRFKDRITILRGNHESRQITQVYG 460
F+IGG +PDTNYLFMGDYVDRGYYSVETV+LLVALKVR++DR+TILRGNHESRQITQVYG
Sbjct: 66 FRIGGNAPDTNYLFMGDYVDRGYYSVETVSLLVALKVRYRDRLTILRGNHESRQITQVYG 125
Query: 461 FYDECLRKYTNANVWKYFTDLFDYLPLT 544
FYDECLRKY NANVWKYFTDLFDYLPLT
Sbjct: 126 FYDECLRKYGNANVWKYFTDLFDYLPLT 153
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,429,083
Number of Sequences: 369166
Number of extensions: 883270
Number of successful extensions: 2958
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2835
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2892
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3783975580
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)