Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_M15
(287 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29598|UROK_RAT Urokinase-type plasminogen activator pre... 50 1e-06
sp|P50343|MCPT6_RAT Mast cell protease 6 precursor (rMCP-6)... 49 4e-06
sp|O18783|PLMN_MACEU Plasminogen precursor [Contains: Plasm... 48 6e-06
sp|P06868|PLMN_BOVIN Plasminogen precursor [Contains: Plasm... 48 8e-06
sp|P00749|UROK_HUMAN Urokinase-type plasminogen activator p... 48 8e-06
sp|Q15661|TRYB1_HUMAN Tryptase beta-1 precursor (Tryptase 1... 47 1e-05
sp|P20231|TRYB2_HUMAN Tryptase beta-2 precursor (Tryptase 2... 47 1e-05
sp|P15157|TRYA_HUMAN Alpha-tryptase precursor (Tryptase 1) 47 1e-05
sp|P28293|CATG_MOUSE Cathepsin G precursor (Vimentin-specif... 47 1e-05
sp|P21845|MCPT6_MOUSE Mast cell protease 6 precursor (MMCP-... 47 1e-05
>sp|P29598|UROK_RAT Urokinase-type plasminogen activator precursor (uPA) (U-plasminogen
activator) [Contains: Urokinase-type plasminogen
activator long chain A; Urokinase-type plasminogen
activator short chain A; Urokinase-type plasminogen
activator chain B]
Length = 432
Score = 50.4 bits (119), Expect = 1e-06
Identities = 22/48 (45%), Positives = 31/48 (64%)
Frame = +2
Query: 41 NGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 184
+G+SGGPLIC+IDG ++G+VS A ++TRV Y L WI+
Sbjct: 374 SGDSGGPLICNIDGRPTLSGIVSWGSGCAEKNKPGVYTRVSYFLNWIQ 421
>sp|P50343|MCPT6_RAT Mast cell protease 6 precursor (rMCP-6) (Tryptase)
Length = 274
Score = 48.9 bits (115), Expect = 4e-06
Identities = 25/59 (42%), Positives = 33/59 (55%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWI 181
C+ N S G+SGGPL+C + G+ + AGVVS A A ++TRV Y L WI
Sbjct: 210 CAGNTRSDSC--QGDSGGPLVCKVKGTWLQAGVVSWGEGCAEANRPGIYTRVTYYLDWI 266
>sp|O18783|PLMN_MACEU Plasminogen precursor [Contains: Plasmin heavy chain A; Activation
peptide; Plasmin heavy chain A, short form; Plasmin
light chain B]
Length = 806
Score = 48.1 bits (113), Expect = 6e-06
Identities = 24/66 (36%), Positives = 34/66 (51%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 184
C+ + +G G+SGGPLIC D V+ GV S + AR ++ RV + WI+
Sbjct: 741 CAGHLVGRGDSCQGDSGGPLICFEDDKYVLQGVTSWGLGCARPNKPGVYVRVSRYISWIE 800
Query: 185 LTMNNN 202
M NN
Sbjct: 801 DVMKNN 806
>sp|P06868|PLMN_BOVIN Plasminogen precursor [Contains: Plasmin heavy chain A; Activation
peptide; Plasmin heavy chain A, short form; Plasmin
light chain B]
Length = 812
Score = 47.8 bits (112), Expect = 8e-06
Identities = 22/66 (33%), Positives = 35/66 (53%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 184
C+ + +G + G+SGGPL+C ++ GV S + AR ++ RV +PWI+
Sbjct: 747 CAGHLIGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSPYVPWIE 806
Query: 185 LTMNNN 202
TM N
Sbjct: 807 ETMRRN 812
>sp|P00749|UROK_HUMAN Urokinase-type plasminogen activator precursor (uPA) (U-plasminogen
activator) [Contains: Urokinase-type plasminogen
activator long chain A; Urokinase-type plasminogen
activator short chain A; Urokinase-type plasminogen
activator chain B]
Length = 431
Score = 47.8 bits (112), Expect = 8e-06
Identities = 20/47 (42%), Positives = 29/47 (61%)
Frame = +2
Query: 44 GESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 184
G+SGGPL+CS+ G + G+VS A ++TRV + LPWI+
Sbjct: 374 GDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR 420
>sp|Q15661|TRYB1_HUMAN Tryptase beta-1 precursor (Tryptase 1) (Tryptase I)
Length = 275
Score = 47.4 bits (111), Expect = 1e-05
Identities = 24/59 (40%), Positives = 34/59 (57%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWI 181
C+ N S G+SGGPL+C ++G+ + AGVVS A+ ++TRV Y L WI
Sbjct: 211 CAGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
>sp|P20231|TRYB2_HUMAN Tryptase beta-2 precursor (Tryptase 2) (Tryptase II)
Length = 275
Score = 47.4 bits (111), Expect = 1e-05
Identities = 24/59 (40%), Positives = 34/59 (57%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWI 181
C+ N S G+SGGPL+C ++G+ + AGVVS A+ ++TRV Y L WI
Sbjct: 211 CAGNTRRDSC--QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267
>sp|P15157|TRYA_HUMAN Alpha-tryptase precursor (Tryptase 1)
Length = 275
Score = 47.4 bits (111), Expect = 1e-05
Identities = 24/59 (40%), Positives = 34/59 (57%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWI 181
C+ N S G+SGGPL+C ++G+ + AGVVS A+ ++TRV Y L WI
Sbjct: 211 CAGNTRRDSC--KGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLDWI 267
>sp|P28293|CATG_MOUSE Cathepsin G precursor (Vimentin-specific protease) (VSP)
Length = 261
Score = 47.0 bits (110), Expect = 1e-05
Identities = 24/63 (38%), Positives = 34/63 (53%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWIK 184
C N + F G+SGGPL+C S V G+VS N+ ++ FT++ +PWIK
Sbjct: 186 CVGNpreRKSAFRGDSGGPLVC----SNVAQGIVSYGSNNGNPPAV--FTKIQSFMPWIK 239
Query: 185 LTM 193
TM
Sbjct: 240 RTM 242
>sp|P21845|MCPT6_MOUSE Mast cell protease 6 precursor (MMCP-6) (Tryptase)
Length = 276
Score = 47.0 bits (110), Expect = 1e-05
Identities = 24/59 (40%), Positives = 33/59 (55%)
Frame = +2
Query: 5 CSDNNMGSSAIFNGESGGPLICSIDGSKVIAGVVSKSINSARATSIRLFTRVDYMLPWI 181
C+ N S G+SGGPL+C + G+ + AGVVS A+ ++TRV Y L WI
Sbjct: 212 CAGNTRRDSC--QGDSGGPLVCKVKGTWLQAGVVSWGEGCAQPNKPGIYTRVTYYLDWI 268
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,578,926
Number of Sequences: 369166
Number of extensions: 568663
Number of successful extensions: 1801
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1666
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1703
length of database: 68,354,980
effective HSP length: 65
effective length of database: 56,347,205
effective search space used: 1690416150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)