Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_K21
(766 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 105 1e-22
sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich... 104 3e-22
sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich... 103 5e-22
sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4 103 5e-22
sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5... 100 6e-21
sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich... 100 6e-21
sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/ser... 99 1e-20
sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/ser... 94 4e-19
sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich... 93 9e-19
sp|Q10021|RSP5_CAEEL Probable splicing factor, arginine/ser... 83 7e-16
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa
bracketing protein) (B52 protein)
Length = 376
Score = 105 bits (262), Expect = 1e-22
Identities = 55/131 (41%), Positives = 76/131 (58%)
Frame = +3
Query: 24 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 203
R+Y+G LP + ERD+++FF+ YGR R + +KNGYGFVE +D RDA+DA+++L+G +LLG
Sbjct: 5 RVYVGGLPYGVRERDLERFFKGYGRTRDILIKNGYGFVEFEDYRDADDAVYELNGKELLG 64
Query: 204 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 383
ERV VE AR A P+R+E+R+I
Sbjct: 65 ERVVVEPARGTA-RGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLI 123
Query: 384 VDGLSSRVSWQ 416
V+ LSSRVSWQ
Sbjct: 124 VENLSSRVSWQ 134
Score = 53.9 bits (128), Expect = 5e-07
Identities = 24/34 (70%), Positives = 30/34 (88%)
Frame = +3
Query: 663 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSD 764
DLKD MR+ GEVT+ADAHK R+N+GVVEF++ SD
Sbjct: 135 DLKDYMRQAGEVTYADAHKQRRNEGVVEFASLSD 168
>sp|Q13247|SFRS6_HUMAN Splicing factor, arginine/serine-rich 6 (Pre-mRNA splicing factor
SRP55)
Length = 344
Score = 104 bits (259), Expect = 3e-22
Identities = 56/133 (42%), Positives = 74/133 (55%)
Frame = +3
Query: 18 MPRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKL 197
MPR+YIG L + E+DI++FF YGR+ VDLKNGYGFVE +D RDA+DA+++L+G +L
Sbjct: 1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKEL 60
Query: 198 LGERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHR 377
GERV VE AR P+R+E+R
Sbjct: 61 CGERVIVEHARG---------PRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYR 111
Query: 378 IIVDGLSSRVSWQ 416
+IV+ LSSR SWQ
Sbjct: 112 LIVENLSSRCSWQ 124
Score = 52.0 bits (123), Expect = 2e-06
Identities = 23/34 (67%), Positives = 28/34 (82%)
Frame = +3
Query: 663 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSD 764
DLKD MR+ GEVT+ADAHK R N+GV+EF + SD
Sbjct: 125 DLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSD 158
>sp|Q08170|SFRS4_HUMAN Splicing factor, arginine/serine-rich 4 (Pre-mRNA splicing factor
SRP75) (SRP001LB)
Length = 494
Score = 103 bits (257), Expect = 5e-22
Identities = 57/133 (42%), Positives = 73/133 (54%)
Frame = +3
Query: 18 MPRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKL 197
MPR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L
Sbjct: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 60
Query: 198 LGERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHR 377
GERV VE AR P R+E+R
Sbjct: 61 CGERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYR 105
Query: 378 IIVDGLSSRVSWQ 416
+IV+ LSSR SWQ
Sbjct: 106 LIVENLSSRCSWQ 118
Score = 51.6 bits (122), Expect = 2e-06
Identities = 23/34 (67%), Positives = 29/34 (85%)
Frame = +3
Query: 663 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSD 764
DLKD MR+ GEVT+ADAHK R+N+GV+EF + SD
Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSD 152
>sp|Q8VE97|SFRS4_MOUSE Splicing factor, arginine/serine-rich 4
Length = 489
Score = 103 bits (257), Expect = 5e-22
Identities = 57/133 (42%), Positives = 73/133 (54%)
Frame = +3
Query: 18 MPRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKL 197
MPR+YIG L + ERD+++FF+ YG+I VDLKNGYGFVE DD RDA+DA+++L+G L
Sbjct: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 60
Query: 198 LGERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHR 377
GERV VE AR P R+E+R
Sbjct: 61 CGERVIVEHARG---------------PRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYR 105
Query: 378 IIVDGLSSRVSWQ 416
+IV+ LSSR SWQ
Sbjct: 106 LIVENLSSRCSWQ 118
Score = 51.6 bits (122), Expect = 2e-06
Identities = 23/34 (67%), Positives = 29/34 (85%)
Frame = +3
Query: 663 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSD 764
DLKD MR+ GEVT+ADAHK R+N+GV+EF + SD
Sbjct: 119 DLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSD 152
>sp|Q09167|SFRS5_RAT Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Insulin-induced growth response protein CL-4)
(Delayed-early protein HRS)
Length = 269
Score = 100 bits (248), Expect = 6e-21
Identities = 52/131 (39%), Positives = 75/131 (57%)
Frame = +3
Query: 24 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 203
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 204 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 383
ERVT+E AR+ + P+R+E+R+I
Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLI 111
Query: 384 VDGLSSRVSWQ 416
V+ LSSRVSWQ
Sbjct: 112 VENLSSRVSWQ 122
Score = 50.1 bits (118), Expect = 7e-06
Identities = 22/34 (64%), Positives = 28/34 (82%)
Frame = +3
Query: 663 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSD 764
DLKD MR+ GEVTFADAH+ + N+GVVEF++ D
Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGD 156
>sp|Q13243|SFRS5_HUMAN Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 272
Score = 100 bits (248), Expect = 6e-21
Identities = 52/131 (39%), Positives = 75/131 (57%)
Frame = +3
Query: 24 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 203
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 204 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 383
ERVT+E AR+ + P+R+E+R+I
Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLI 111
Query: 384 VDGLSSRVSWQ 416
V+ LSSRVSWQ
Sbjct: 112 VENLSSRVSWQ 122
Score = 50.1 bits (118), Expect = 7e-06
Identities = 22/34 (64%), Positives = 28/34 (82%)
Frame = +3
Query: 663 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSD 764
DLKD MR+ GEVTFADAH+ + N+GVVEF++ D
Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGD 156
>sp|Q23121|RSP1_CAEEL Probable splicing factor, arginine/serine-rich 1 (RNA-binding
protein srp-5) (CeSRp75)
Length = 312
Score = 99.0 bits (245), Expect = 1e-20
Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 9/140 (6%)
Frame = +3
Query: 24 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 203
R+YIG L R+ E+DI+ FFR YG+IR V LKNG+GFVE DD+RDAEDA+HDL+G +L G
Sbjct: 4 RIYIGRLTSRVSEKDIEHFFRGYGQIRDVLLKNGFGFVEFDDKRDAEDAVHDLNGKELGG 63
Query: 204 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIR------ 365
ERV ++ ++ P R
Sbjct: 64 ERVILDYSKPRGGGGDRGGFGGGGRGGARVSSYSGGGGGGRDRFDRYDRGPPRRESRYGR 123
Query: 366 ---SEHRIIVDGLSSRVSWQ 416
+ HR++V+ LSSR+SWQ
Sbjct: 124 PYSTRHRVVVENLSSRISWQ 143
>sp|Q23120|RSP2_CAEEL Probable splicing factor, arginine/serine-rich 2 (RNA-binding
protein srp-4) (CeSRp40)
Length = 281
Score = 94.0 bits (232), Expect = 4e-19
Identities = 48/133 (36%), Positives = 69/133 (51%)
Frame = +3
Query: 18 MPRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKL 197
M R+YIG LP R +RD++ FFR YG++ V +KNG+GFV+ D+RDA+DA+HDL+G +L
Sbjct: 1 MVRVYIGRLPNRASDRDVEHFFRGYGKLSDVIMKNGFGFVDFQDQRDADDAVHDLNGKEL 60
Query: 198 LGERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHR 377
GERV +E R +P + R
Sbjct: 61 CGERVILEFPRRKV-------GYNEERSGSGFRGREPTFRKGGERQFSNRYSRPCSTRFR 113
Query: 378 IIVDGLSSRVSWQ 416
+++D LS+R SWQ
Sbjct: 114 LVIDNLSTRYSWQ 126
>sp|O35326|SFRS5_MOUSE Splicing factor, arginine/serine-rich 5 (Pre-mRNA splicing factor
SRP40) (Delayed-early protein HRS)
Length = 270
Score = 92.8 bits (229), Expect = 9e-19
Identities = 49/131 (37%), Positives = 72/131 (54%)
Frame = +3
Query: 24 RLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKLLG 203
R++IG L E+D+++FF+ YGRIR +DLK G+GFVE +D RDA+DA+++LDG +L
Sbjct: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
Query: 204 ERVTVEMARSNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKPIRSEHRII 383
ERVT+E AR+ + ++ +R+I
Sbjct: 65 ERVTIEHARARS-------------RGGRGRGRYSDRLAVADLGNDRRKCSTCKNRNRLI 111
Query: 384 VDGLSSRVSWQ 416
V+ LSSRVSWQ
Sbjct: 112 VENLSSRVSWQ 122
Score = 50.1 bits (118), Expect = 7e-06
Identities = 22/34 (64%), Positives = 28/34 (82%)
Frame = +3
Query: 663 DLKDLMRKVGEVTFADAHKLRQNQGVVEFSNSSD 764
DLKD MR+ GEVTFADAH+ + N+GVVEF++ D
Sbjct: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGD 156
>sp|Q10021|RSP5_CAEEL Probable splicing factor, arginine/serine-rich 5 (RNA-binding
protein srp-3) (CeSC35-2)
Length = 208
Score = 83.2 bits (204), Expect = 7e-16
Identities = 37/73 (50%), Positives = 52/73 (71%), Gaps = 2/73 (2%)
Frame = +3
Query: 18 MPRLYIGNLPRRIEERDIKKFFREYGRIRSVDLKNGYGFVEIDDRRDAEDAIHDLDGTKL 197
MPRLY+G +P ERD+++F + YG+I ++ +K G+ FV+ +D RDAEDA HDLDG +
Sbjct: 1 MPRLYLGKIPYNARERDVERFLKGYGKINNISMKYGFAFVDFEDSRDAEDACHDLDGKTM 60
Query: 198 LGE--RVTVEMAR 230
G R+ VEMAR
Sbjct: 61 EGSSMRLVVEMAR 73
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,422,276
Number of Sequences: 369166
Number of extensions: 1526507
Number of successful extensions: 3538
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3241
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3464
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7066925600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)