Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_K17
(848 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9R0M8|S35A2_MOUSE UDP-galactose translocator (UDP-galac... 180 5e-45
sp|P78381|S35A2_HUMAN UDP-galactose translocator (UDP-galac... 179 1e-44
sp|Q93890|SRF3_CAEEL UDP-galactose/UDP-N-acetylglucosamine ... 173 6e-43
sp|Q6YC49|S35A3_BOVIN UDP-N-acetylglucosamine transporter (... 171 2e-42
sp|O77592|S35A3_CANFA UDP-N-acetylglucosamine transporter (... 171 3e-42
sp|Q9Y2D2|S35A3_HUMAN UDP-N-acetylglucosamine transporter (... 169 7e-42
sp|Q8R1T4|S35A3_MOUSE UDP-N-acetylglucosamine transporter (... 169 9e-42
sp|P87041|GMS1_SCHPO UDP-galactose transporter (Golgi UDP-G... 166 6e-41
sp|Q6AXR5|S35A3_RAT UDP-N-acetylglucosamine transporter (Go... 166 6e-41
sp|Q61420|S35A1_MOUSE CMP-sialic acid transporter (CMP-Sia-... 166 8e-41
>sp|Q9R0M8|S35A2_MOUSE UDP-galactose translocator (UDP-galactose transporter) (UGT)
(UDP-Gal-Tr) (Solute carrier family 35 member A2)
(mUGT1)
Length = 390
Score = 180 bits (456), Expect = 5e-45
Identities = 98/236 (41%), Positives = 146/236 (61%), Gaps = 6/236 (2%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTELFFTSSVIIVTEIVK-LLISLVVFCYQNGIK 293
+K +SL +L +QNAS IL +RY RT + FF ++ +++ E++K L L++F + G
Sbjct: 35 LKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNV 94
Query: 294 K-----LYHETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTTAV 458
K L+ D++K+ VP++IY LQNNL YVA+SNL +A FQV+YQLK+LTTA+
Sbjct: 95 KHLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTAL 154
Query: 459 FSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSDSSKGVADGLVQNKVMGMAAVLTACV 638
FSV +L +++ ++QW SL LLF GV +VQ S D QN G+AAV+ +C+
Sbjct: 155 FSVLMLNRSLSRLQWASLLLLFTGVAIVQAQQAGGSGPRPLD---QNPGAGLAAVVASCL 211
Query: 639 MSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGF 806
SGFAG++FEK LK S S+W RN+ + E A++ +GFF+G+
Sbjct: 212 SSGFAGVYFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTAVASQGFFFGY 267
>sp|P78381|S35A2_HUMAN UDP-galactose translocator (UDP-galactose transporter) (UGT)
(UDP-Gal-Tr) (Solute carrier family 35 member A2)
Length = 396
Score = 179 bits (453), Expect = 1e-44
Identities = 98/236 (41%), Positives = 147/236 (62%), Gaps = 6/236 (2%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTELFFTSSVIIVTEIVK-LLISLVVFCYQNGIK 293
+K +SL +L +QNAS IL +RY RT + FF ++ +++ E++K L L++F + G
Sbjct: 35 LKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNV 94
Query: 294 K-----LYHETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTTAV 458
K L+ D++K+ VP++IY LQNNL YVA+SNL +A FQV+YQLK+LTTA+
Sbjct: 95 KHLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTAL 154
Query: 459 FSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSDSSKGVADGLVQNKVMGMAAVLTACV 638
FSV +L +++ ++QW SL LLF GV +VQ + G L QN G+AAV+ +C+
Sbjct: 155 FSVLMLNRSLSRLQWASLLLLFTGVAIVQ---AQQAGGGGPRPLDQNPGAGLAAVVASCL 211
Query: 639 MSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGF 806
SGFAG++FEK LK S S+W RN+ + E A++ +GFF+G+
Sbjct: 212 SSGFAGVYFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTAVATRGFFFGY 267
>sp|Q93890|SRF3_CAEEL UDP-galactose/UDP-N-acetylglucosamine transporter srf-3 (Surface
antigenicity abnormal 3)
Length = 328
Score = 173 bits (438), Expect = 6e-43
Identities = 96/243 (39%), Positives = 147/243 (60%), Gaps = 7/243 (2%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTELFFTSSVII-VTEIVKLLISLVVFCYQNGIK 293
+K LI LT+QN+ H L++RY R R + F S+V + +TE++K I L + + +
Sbjct: 1 MKTAILIWLTLQNSIHTLLIRYSRAREVDAMFVSTVAVWLTEVIKCFICLFLVAQEETPR 60
Query: 294 KLYHETFNDIT----DSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTTAVF 461
+ H I D++KV +PA+IY++QNNL YVA S+LD+A F ++ QLK+ T A+F
Sbjct: 61 RFIHALRTQILEQPYDTLKVCIPAMIYIVQNNLFYVAASHLDAATFMITSQLKIFTAAIF 120
Query: 462 SVFLLKQNILKMQWLSLFLLFMGVGLVQLD-TTSDSSKGVADGLVQNKVMGMAAVLTACV 638
+V +L++++ + QW +L +LF+GV LVQL T + S G ++ +G AV+ AC
Sbjct: 121 TVIILRRSLNRTQWFALAVLFVGVSLVQLQGTKAKESSG------ESPFVGFVAVVVACC 174
Query: 639 MSGFAGIFFEKTLKSSV-ISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGFDIM 815
+SGFAGI+FEK LK S +SLW RNV MA + + +++ G YGFD +
Sbjct: 175 LSGFAGIYFEKILKGSAPVSLWMRNVQMAVFSIPASFSAIYMQDSKTVNEYGLLYGFDSI 234
Query: 816 VCL 824
V L
Sbjct: 235 VWL 237
>sp|Q6YC49|S35A3_BOVIN UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter)
(Solute carrier family 35 member A3)
Length = 326
Score = 171 bits (433), Expect = 2e-42
Identities = 97/241 (40%), Positives = 148/241 (61%), Gaps = 10/241 (4%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTE--LFFTSSVIIVTEIVKLLISLVVF-----C 275
+K LSL +L Q S +L MRY RT E + +S+ ++V E++K++ +++ C
Sbjct: 5 LKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKC 64
Query: 276 YQNGIKKLYH-ETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTT 452
+ ++ H E N +++K+ +P+ IY LQNNLLYVALSNLD+A +QV+YQLK+LTT
Sbjct: 65 SLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTT 124
Query: 453 AVFSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSD--SSKGVADGLVQNKVMGMAAVL 626
A+FSV +L + + QWLSL +L GV VQ + S +SK ++ G ++ +G+ AVL
Sbjct: 125 ALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPSDSQELNSKELSAG---SQFVGLMAVL 181
Query: 627 TACVMSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGF 806
TAC SGFAG++FEK LK + S+W RN+ + Y+ E +S GFF G+
Sbjct: 182 TACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGY 241
Query: 807 D 809
+
Sbjct: 242 N 242
>sp|O77592|S35A3_CANFA UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter)
(Solute carrier family 35 member A3)
Length = 326
Score = 171 bits (432), Expect = 3e-42
Identities = 97/241 (40%), Positives = 147/241 (60%), Gaps = 10/241 (4%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTE--LFFTSSVIIVTEIVKLLISLVVF-----C 275
+K LSL +L Q S +L MRY RT E + +S+ ++V E++K++ +++ C
Sbjct: 5 LKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKC 64
Query: 276 YQNGIKKLYH-ETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTT 452
+ ++ H E N +++K+ +P+ IY LQNNLLYVALSNLD+A +QV+YQLK+LTT
Sbjct: 65 SLRALNRILHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTT 124
Query: 453 AVFSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSD--SSKGVADGLVQNKVMGMAAVL 626
A+FSV +L + + QWLSL +L GV VQ + S SK ++ G ++ +G+ AVL
Sbjct: 125 ALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPSDSQELDSKELSAG---SQFVGLMAVL 181
Query: 627 TACVMSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGF 806
TAC SGFAG++FEK LK + S+W RN+ + Y+ E +S GFF G+
Sbjct: 182 TACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGY 241
Query: 807 D 809
+
Sbjct: 242 N 242
>sp|Q9Y2D2|S35A3_HUMAN UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter)
(Solute carrier family 35 member A3)
Length = 325
Score = 169 bits (429), Expect = 7e-42
Identities = 96/240 (40%), Positives = 147/240 (61%), Gaps = 9/240 (3%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTE--LFFTSSVIIVTEIVKLLISLVVF-----C 275
+K +SL +L Q S +L MRY RT E + +S+ ++V E++K++ +++ C
Sbjct: 5 LKYVSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKC 64
Query: 276 YQNGIKKLYH-ETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTT 452
+ ++ H E N +++K+ +P+ IY LQNNLLYVALSNLD+A +QV+YQLK+LTT
Sbjct: 65 SLRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTT 124
Query: 453 AVFSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSD-SSKGVADGLVQNKVMGMAAVLT 629
A+FSV +L + + QWLSL +L GV VQ + S SK ++ G ++ +G+ AVLT
Sbjct: 125 ALFSVSMLSKKLGVYQWLSLVILMTGVAFVQWPSDSQLDSKELSAG---SQFVGLMAVLT 181
Query: 630 ACVMSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGFD 809
AC SGFAG++FEK LK + S+W RN+ + Y+ E +S GFF G++
Sbjct: 182 ACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYN 241
>sp|Q8R1T4|S35A3_MOUSE UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter)
(Solute carrier family 35 member A3)
Length = 326
Score = 169 bits (428), Expect = 9e-42
Identities = 97/241 (40%), Positives = 146/241 (60%), Gaps = 10/241 (4%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTE--LFFTSSVIIVTEIVKLLISLVVF-----C 275
+K LSL +L Q S +L MRY RT E + +S+ ++V E +K++ + + C
Sbjct: 5 LKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAEFLKIMACIFLVYKDSKC 64
Query: 276 YQNGIKKLYH-ETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTT 452
+ ++ H E N +++K+ +P+ IY LQNNLLYVALSNLD+A +QV+YQLK+LTT
Sbjct: 65 SVRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTT 124
Query: 453 AVFSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSD--SSKGVADGLVQNKVMGMAAVL 626
A+FSV +L + + QWLSL +L GV VQ + S +SK ++ G ++ +G+ AVL
Sbjct: 125 ALFSVSMLGKKLGVYQWLSLVILMAGVAFVQWPSDSQELNSKDLSTG---SQFVGLMAVL 181
Query: 627 TACVMSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGF 806
TAC SGFAG++FEK LK + S+W RN+ + Y+ E +S GFF G+
Sbjct: 182 TACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGY 241
Query: 807 D 809
+
Sbjct: 242 N 242
>sp|P87041|GMS1_SCHPO UDP-galactose transporter (Golgi UDP-Gal transporter)
Length = 353
Score = 166 bits (421), Expect = 6e-41
Identities = 97/250 (38%), Positives = 148/250 (59%), Gaps = 11/250 (4%)
Frame = +3
Query: 108 MKYIKELSLILLTIQNASHILMMRYCRTRT---TELFFTSSVIIVTEIVKLLISLVVFCY 278
MKYI +L+LLT+QN++ IL + Y R + +FTS+ +++ E++KL++ V +
Sbjct: 15 MKYI---ALVLLTVQNSALILTLNYSRIMPGYDDKRYFTSTAVLLNELIKLVVCFSVGYH 71
Query: 279 Q--------NGIKKLYHETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQ 434
Q ++ + F DS K+ +PA +Y QNNL YVA NL +A FQV+YQ
Sbjct: 72 QFRKNVGKEAKLRAFLPQIFGG--DSWKLAIPAFLYTCQNNLQYVAAGNLTAASFQVTYQ 129
Query: 435 LKLLTTAVFSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSDSSKGVADGLVQNKVMGM 614
LK+LTTA+FS+ LL + + M+W SLFLL G+ +VQL + + A + N V G
Sbjct: 130 LKILTTAIFSILLLHRRLGPMKWFSLFLLTGGIAIVQLQNLNSDDQMSAGPM--NPVTGF 187
Query: 615 AAVLTACVMSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGF 794
+AVL AC++SG AG++FEK LK + SLW RNV ++ +Y I++ GF
Sbjct: 188 SAVLVACLISGLAGVYFEKVLKDTNPSLWVRNVQLSFFSLFPCLFTILMKDYHNIAENGF 247
Query: 795 FYGFDIMVCL 824
F+G++ +V L
Sbjct: 248 FFGYNSIVWL 257
>sp|Q6AXR5|S35A3_RAT UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter)
(Solute carrier family 35 member A3)
Length = 326
Score = 166 bits (421), Expect = 6e-41
Identities = 96/241 (39%), Positives = 145/241 (60%), Gaps = 10/241 (4%)
Frame = +3
Query: 117 IKELSLILLTIQNASHILMMRYCRTRTTE--LFFTSSVIIVTEIVKLLISLVVF-----C 275
+K LSL +L Q S +L MRY RT E + +S+ ++V E +K++ + + C
Sbjct: 5 LKYLSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAEFLKIMACIFLVYKDSKC 64
Query: 276 YQNGIKKLYH-ETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTT 452
+ ++ H E N +++K+ +P+ IY LQNNLLYVALSNLD+A +QV+YQLK+LTT
Sbjct: 65 SVRTLNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTT 124
Query: 453 AVFSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSD--SSKGVADGLVQNKVMGMAAVL 626
A+FSV +L + + QWLSL +L GV VQ + S +SK ++ G ++ +G+ AVL
Sbjct: 125 ALFSVSMLGKKLGMYQWLSLVILMAGVAFVQWPSDSQELNSKDLSTG---SQFVGLMAVL 181
Query: 627 TACVMSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGF 806
AC SGFAG++FEK LK + S+W RN+ + Y+ E +S GFF G+
Sbjct: 182 IACFSSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYVYDGELVSKNGFFQGY 241
Query: 807 D 809
+
Sbjct: 242 N 242
>sp|Q61420|S35A1_MOUSE CMP-sialic acid transporter (CMP-Sia-Tr) (CMP-SA-Tr) (Solute
carrier family 35 member A1)
Length = 336
Score = 166 bits (420), Expect = 8e-41
Identities = 91/245 (37%), Positives = 143/245 (58%), Gaps = 5/245 (2%)
Frame = +3
Query: 114 YIKELSLILLTIQNASHILMMRYCRTRTTELFFTSSVIIVTEIVKLLISLVVFCYQNGI- 290
+ K L ++T+ A++ + +RY RT EL+F+++ + +TE++KLLIS+ + + G
Sbjct: 11 FFKLYCLAVMTLVAAAYTVALRYTRTTAEELYFSTTAVCITEVIKLLISVGLLAKETGSL 70
Query: 291 ----KKLYHETFNDITDSIKVIVPAVIYVLQNNLLYVALSNLDSAVFQVSYQLKLLTTAV 458
L + K+ VP+++Y +QNN+ ++ALSNLD+AV+QV+YQLK+ TA+
Sbjct: 71 GRFKASLSENVLGSPKELAKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTAL 130
Query: 459 FSVFLLKQNILKMQWLSLFLLFMGVGLVQLDTTSDSSKGVADGLVQNKVMGMAAVLTACV 638
+V +L + + K+QW+S+F+L GV LVQ S VA QN ++G A+ A +
Sbjct: 131 CTVLMLNRTLSKLQWISVFMLCGGVTLVQWKPAQASKVVVA----QNPLLGFGAIAIAVL 186
Query: 639 MSGFAGIFFEKTLKSSVISLWARNVLMAXXXXXXXXXXXXXYEYEAISDKGFFYGFDIMV 818
SGFAG++FEK LKSS SLW RN+ M + I +KGFFYG+ V
Sbjct: 187 CSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIVVTLAGTYLSDGAEIQEKGFFYGYTYYV 246
Query: 819 CLLNF 833
+ F
Sbjct: 247 WFVIF 251
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,626,552
Number of Sequences: 369166
Number of extensions: 1549838
Number of successful extensions: 3748
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3614
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3716
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)